HUE045300T2 - Imidazopiridin származékok, mint receptor tirozin kinázok inhibitorai - Google Patents

Imidazopiridin származékok, mint receptor tirozin kinázok inhibitorai

Info

Publication number
HUE045300T2
HUE045300T2 HUE09761801A HUE09761801A HUE045300T2 HU E045300 T2 HUE045300 T2 HU E045300T2 HU E09761801 A HUE09761801 A HU E09761801A HU E09761801 A HUE09761801 A HU E09761801A HU E045300 T2 HUE045300 T2 HU E045300T2
Authority
HU
Hungary
Prior art keywords
inhibitors
receptor tyrosine
tyrosine kinases
imidazopyridine derivatives
imidazopyridine
Prior art date
Application number
HUE09761801A
Other languages
English (en)
Hungarian (hu)
Inventor
Valerio Berdini
Maria Carr
Miles Congreve
Martyn Frederickson
Charlotte Griffiths-Jones
Christopher Hamlett
Andrew Madin
Christopher Murray
Rajdeep Kaur Benning
Gordon Saxty
Emma Vickerstaffe
Andrew Woodhead
Steven Woodhead
Eddy Freyne
Tom Govaerts
Patrick Angibaud
Brian Williams
Original Assignee
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astex Therapeutics Ltd filed Critical Astex Therapeutics Ltd
Publication of HUE045300T2 publication Critical patent/HUE045300T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HUE09761801A 2008-06-13 2009-06-12 Imidazopiridin származékok, mint receptor tirozin kinázok inhibitorai HUE045300T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6118408P 2008-06-13 2008-06-13
GBGB0810902.7A GB0810902D0 (en) 2008-06-13 2008-06-13 New compounds

Publications (1)

Publication Number Publication Date
HUE045300T2 true HUE045300T2 (hu) 2019-12-30

Family

ID=39672279

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE09761801A HUE045300T2 (hu) 2008-06-13 2009-06-12 Imidazopiridin származékok, mint receptor tirozin kinázok inhibitorai

Country Status (21)

Country Link
US (1) US8796244B2 (https=)
EP (1) EP2300465B1 (https=)
JP (1) JP5596023B2 (https=)
KR (1) KR101745730B1 (https=)
CN (1) CN102137859B (https=)
AU (1) AU2009256584B2 (https=)
BR (1) BRPI0915084B8 (https=)
CA (1) CA2727062A1 (https=)
DK (1) DK2300465T3 (https=)
ES (1) ES2735979T3 (https=)
GB (1) GB0810902D0 (https=)
HR (1) HRP20191027T1 (https=)
HU (1) HUE045300T2 (https=)
IL (1) IL209864A (https=)
LT (1) LT2300465T (https=)
MX (1) MX2010013743A (https=)
NZ (1) NZ589781A (https=)
RU (1) RU2518089C2 (https=)
SI (1) SI2300465T1 (https=)
WO (1) WO2009150240A1 (https=)
ZA (1) ZA201008961B (https=)

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US20120208791A1 (en) 2012-08-16
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ES2735979T3 (es) 2019-12-23
BRPI0915084B8 (pt) 2021-05-25
EP2300465B1 (en) 2019-04-17
AU2009256584B2 (en) 2014-06-12
IL209864A (en) 2015-10-29
KR101745730B1 (ko) 2017-06-12
CN102137859B (zh) 2015-07-01
AU2009256584A1 (en) 2009-12-17
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BRPI0915084A2 (pt) 2015-10-27
ZA201008961B (en) 2015-05-27
BRPI0915084B1 (pt) 2020-02-11
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SI2300465T1 (sl) 2019-08-30
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