HUE037312T2 - Hiszton demetiláz inhibitorok - Google Patents
Hiszton demetiláz inhibitorokInfo
- Publication number
- HUE037312T2 HUE037312T2 HUE13866465A HUE13866465A HUE037312T2 HU E037312 T2 HUE037312 T2 HU E037312T2 HU E13866465 A HUE13866465 A HU E13866465A HU E13866465 A HUE13866465 A HU E13866465A HU E037312 T2 HUE037312 T2 HU E037312T2
- Authority
- HU
- Hungary
- Prior art keywords
- histone demethylase
- demethylase inhibitors
- inhibitors
- histone
- demethylase
- Prior art date
Links
- 102000008157 Histone Demethylases Human genes 0.000 title 1
- 108010074870 Histone Demethylases Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261739521P | 2012-12-19 | 2012-12-19 | |
| US201361792930P | 2013-03-15 | 2013-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE037312T2 true HUE037312T2 (hu) | 2018-08-28 |
Family
ID=50931614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE13866465A HUE037312T2 (hu) | 2012-12-19 | 2013-12-19 | Hiszton demetiláz inhibitorok |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US8969343B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2934145B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6256772B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2013361255B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2895355A1 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1119901T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2934145T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2658597T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20180067T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE037312T2 (cg-RX-API-DMAC7.html) |
| LT (1) | LT2934145T (cg-RX-API-DMAC7.html) |
| PL (1) | PL2934145T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2934145T (cg-RX-API-DMAC7.html) |
| RS (1) | RS56821B1 (cg-RX-API-DMAC7.html) |
| SI (1) | SI2934145T1 (cg-RX-API-DMAC7.html) |
| SM (1) | SMT201800070T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014100463A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (68)
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| CN113679717A (zh) | 2012-08-22 | 2021-11-23 | 康奈尔大学 | 用于抑制肌成束蛋白的方法 |
| RS55764B1 (sr) | 2012-10-02 | 2017-07-31 | Gilead Sciences | Inhibitori histonskih demetilaza |
| AU2013361255B2 (en) | 2012-12-19 | 2017-01-05 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| AU2013363957B2 (en) | 2012-12-21 | 2018-03-22 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| JP6514117B2 (ja) | 2013-02-27 | 2019-05-15 | エピセラピューティクス アーペーエス | ヒストン脱メチル化酵素の阻害剤 |
| JP6320506B2 (ja) | 2013-03-12 | 2018-05-09 | セルジーン クオンティセル リサーチ，インク． | ヒストンデメチラーゼ阻害剤 |
| CN105980386B (zh) | 2013-03-13 | 2021-08-13 | 基因泰克公司 | 吡唑并化合物及其用途 |
| US9573946B2 (en) | 2014-02-20 | 2017-02-21 | Novita Pharmaceuticals, Inc. | Compounds and methods for inhibiting fascin |
| EP3738960A1 (en) | 2014-06-25 | 2020-11-18 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| JP2017526675A (ja) | 2014-08-27 | 2017-09-14 | ギリアード サイエンシーズ， インコーポレイテッド | ヒストンデメチラーゼを阻害するための化合物および方法 |
| US10030017B2 (en) | 2014-09-17 | 2018-07-24 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| JP6552608B2 (ja) | 2014-09-17 | 2019-07-31 | セルジーン クオンティセル リサーチ，インク． | ヒストンデメチラーゼ阻害剤 |
| MX2017003463A (es) | 2014-09-17 | 2017-07-13 | Celgene Quanticel Res Inc | Inhibidores de histona desmetilasa. |
| WO2017117154A1 (en) * | 2015-12-28 | 2017-07-06 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| CN105601555B (zh) * | 2016-03-14 | 2018-07-31 | 苏州大学 | 一种制备硝基吲哚衍生物的方法 |
| WO2017161012A1 (en) * | 2016-03-15 | 2017-09-21 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| US10150754B2 (en) | 2016-04-19 | 2018-12-11 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| BR102017010009A2 (pt) | 2016-05-27 | 2017-12-12 | Gilead Sciences, Inc. | Compounds for the treatment of hepatitis b virus infection |
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| US7442698B2 (en) * | 2003-07-24 | 2008-10-28 | Amgen Inc. | Substituted heterocyclic compounds and methods of use |
| FR2882361A1 (fr) | 2005-02-22 | 2006-08-25 | Aventis Pharma Sa | Nouveaux derives de 3-aryl-1,2-benzisoxazole, compositions les contenant et leur utilisation |
| EP2069020B1 (en) * | 2006-07-20 | 2010-01-27 | Amgen Inc. | Benzo[d]isoxazole derivatives as c-kit tyrosine kinase inhibitors for the treatment of disorders associated with the over production of histamine |
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| AU2013361255B2 (en) | 2012-12-19 | 2017-01-05 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
-
2013
- 2013-12-19 AU AU2013361255A patent/AU2013361255B2/en not_active Ceased
- 2013-12-19 DK DK13866465.1T patent/DK2934145T3/en active
- 2013-12-19 PL PL13866465T patent/PL2934145T3/pl unknown
- 2013-12-19 HR HRP20180067TT patent/HRP20180067T1/hr unknown
- 2013-12-19 PT PT138664651T patent/PT2934145T/pt unknown
- 2013-12-19 CA CA2895355A patent/CA2895355A1/en not_active Abandoned
- 2013-12-19 US US14/134,989 patent/US8969343B2/en active Active
- 2013-12-19 SI SI201330913T patent/SI2934145T1/en unknown
- 2013-12-19 WO PCT/US2013/076666 patent/WO2014100463A1/en not_active Ceased
- 2013-12-19 SM SM20180070T patent/SMT201800070T1/it unknown
- 2013-12-19 US US14/653,818 patent/US9617242B2/en active Active
- 2013-12-19 EP EP13866465.1A patent/EP2934145B1/en active Active
- 2013-12-19 HU HUE13866465A patent/HUE037312T2/hu unknown
- 2013-12-19 LT LTEP13866465.1T patent/LT2934145T/lt unknown
- 2013-12-19 ES ES13866465.1T patent/ES2658597T3/es active Active
- 2013-12-19 JP JP2015549728A patent/JP6256772B2/ja not_active Expired - Fee Related
- 2013-12-19 RS RS20180071A patent/RS56821B1/sr unknown
-
2017
- 2017-03-01 US US15/446,996 patent/US10040779B2/en active Active
-
2018
- 2018-02-09 CY CY20181100164T patent/CY1119901T1/el unknown
- 2018-06-29 US US16/024,452 patent/US10336727B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| LT2934145T (lt) | 2018-02-26 |
| CY1119901T1 (el) | 2018-06-27 |
| JP6256772B2 (ja) | 2018-01-10 |
| US20140171432A1 (en) | 2014-06-19 |
| US20160060247A1 (en) | 2016-03-03 |
| EP2934145B1 (en) | 2017-11-15 |
| EP2934145A1 (en) | 2015-10-28 |
| SI2934145T1 (en) | 2018-03-30 |
| US8969343B2 (en) | 2015-03-03 |
| US10336727B2 (en) | 2019-07-02 |
| EP2934145A4 (en) | 2016-06-29 |
| AU2013361255A1 (en) | 2015-07-09 |
| PT2934145T (pt) | 2018-02-13 |
| DK2934145T3 (en) | 2018-02-05 |
| CA2895355A1 (en) | 2014-06-26 |
| HRP20180067T1 (hr) | 2018-02-23 |
| JP2016503799A (ja) | 2016-02-08 |
| RS56821B1 (sr) | 2018-04-30 |
| AU2013361255B2 (en) | 2017-01-05 |
| US20180305336A1 (en) | 2018-10-25 |
| SMT201800070T1 (it) | 2018-03-08 |
| US10040779B2 (en) | 2018-08-07 |
| PL2934145T3 (pl) | 2018-04-30 |
| US9617242B2 (en) | 2017-04-11 |
| US20170174656A1 (en) | 2017-06-22 |
| ES2658597T3 (es) | 2018-03-12 |
| WO2014100463A1 (en) | 2014-06-26 |
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