HUE035043T2 - Gyógyászati készítmény károsodott szövet funkcionális regenerációjának elõsegítésére - Google Patents

Gyógyászati készítmény károsodott szövet funkcionális regenerációjának elõsegítésére Download PDF

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Publication number
HUE035043T2
HUE035043T2 HUE07830867A HUE07830867A HUE035043T2 HU E035043 T2 HUE035043 T2 HU E035043T2 HU E07830867 A HUE07830867 A HU E07830867A HU E07830867 A HUE07830867 A HU E07830867A HU E035043 T2 HUE035043 T2 HU E035043T2
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lys
cells
protein
bone marrow
glu
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HUE07830867A
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Katsuto Tamai
Takehiko Yamazaki
Yasufumi Kaneda
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Genomix Co Ltd
Univ Osaka
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Publication of HUE035043T2 publication Critical patent/HUE035043T2/hu

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

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  • Life Sciences & Earth Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Tropical Medicine & Parasitology (AREA)
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Claims (2)

  1. GYÓGYÁSZATI KÉSZÍTMÉNY KÁROSODOTT SZÖVET FUNKCIONÁLIS REGENERÁCIÓJÁNAK ELŐSEGÍTÉSÉRE Szabadalmi igénypertto k
    1. Szövetregenerációs promóter, amely tartalmazza a következő (a) - fi) összetevők bármelyikét, epite-liális szövet vagy idegszövet regeneratív gyógyászatában való alkalmazásra: (a) UM« EB-fehérje (hí BMGB1 'fehérjét szekretáló sejt; (ej HM« EH-fehérjét kódoló DNS-t mszertálva tartalmazó vektor; (dí EÍMGBT-fehérje; (e) HMGEHí-fehérjét szekretáló sejt; (f) H.MCíB2-fehérjéf. kódoló DNS-t insz.ertálva tartalmazó: vektor: (g) ! IMGB.Tíeítéfjt;; (h) HM GfEMehéxjót szskreíátó sejt ; (I) WMGB3~fehórjét kódoló .DNS-t mszertálva tartalmazó vektor,
  2. 2. Készlet, amely tartalmazza a következő (a) - íij összetevők bármelyikét, epüebális szövet vagy Idegszövet regeneratív gyógyászatában való alkalmazásra: (a ) HM« B1 -fehérje; (b) HMGB I -fehérjét szekretáló sejt; (c) . HMO1B-fehérjét kódoló DNS-t tnszenálva tartalmazó vektor : td ) 11M« 132- fehérje: (e) TlMGUT-fehérjét szekretáló sejt: (f) HM«B2-fehérjéí kódoló DNS-t kisxertáíva tartalmazó vektor; ( g) 11M« B3 - fehérje : (It) HMGBo-fehétjét szekretáló sejt; (t) HMöHo-febétjét kódoló f.)NS-t inszertálva tartalmazó vöktor.
HUE07830867A 2006-10-30 2007-10-30 Gyógyászati készítmény károsodott szövet funkcionális regenerációjának elõsegítésére HUE035043T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006293582 2006-10-30

Publications (1)

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HUE035043T2 true HUE035043T2 (hu) 2018-05-02

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HUE07830867A HUE035043T2 (hu) 2006-10-30 2007-10-30 Gyógyászati készítmény károsodott szövet funkcionális regenerációjának elõsegítésére

Country Status (13)

Country Link
US (2) US20090202500A1 (hu)
EP (1) EP2055308B1 (hu)
JP (2) JP5308161B2 (hu)
KR (2) KR20140115373A (hu)
CN (1) CN101374538A (hu)
AU (1) AU2007315073A1 (hu)
CA (1) CA2636788A1 (hu)
DK (1) DK2055308T3 (hu)
ES (1) ES2629086T3 (hu)
HU (1) HUE035043T2 (hu)
PL (1) PL2055308T3 (hu)
PT (1) PT2055308T (hu)
WO (1) WO2008053892A1 (hu)

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JP2013227330A (ja) 2013-11-07
JP5308161B2 (ja) 2013-10-09
AU2007315073A1 (en) 2008-05-08
WO2008053892A1 (fr) 2008-05-08
KR20090078304A (ko) 2009-07-17
EP2055308B1 (en) 2017-05-10
CA2636788A1 (en) 2008-05-08
US20240050460A1 (en) 2024-02-15
PT2055308T (pt) 2017-07-05
US20090202500A1 (en) 2009-08-13
EP2055308A1 (en) 2009-05-06
EP2055308A4 (en) 2010-10-27
CN101374538A (zh) 2009-02-25
DK2055308T3 (en) 2017-07-17
KR20140115373A (ko) 2014-09-30
JPWO2008053892A1 (ja) 2010-02-25
ES2629086T3 (es) 2017-08-07
PL2055308T3 (pl) 2017-11-30

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