HUE031939T2 - Orális adagolásra alkalmas, triazol[4,5-d]pirimidin származékot tartalmazó készítmények - Google Patents

Orális adagolásra alkalmas, triazol[4,5-d]pirimidin származékot tartalmazó készítmények Download PDF

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Publication number
HUE031939T2
HUE031939T2 HUE07794121A HUE07794121A HUE031939T2 HU E031939 T2 HUE031939 T2 HU E031939T2 HU E07794121 A HUE07794121 A HU E07794121A HU E07794121 A HUE07794121 A HU E07794121A HU E031939 T2 HUE031939 T2 HU E031939T2
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HU
Hungary
Prior art keywords
pharmaceutical composition
mas
aal
weight
agent
Prior art date
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HUE07794121A
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English (en)
Inventor
Simon Banks
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39107049&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE031939(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HUE031939T2 publication Critical patent/HUE031939T2/hu

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Claims (4)

  1. ORÁLIS Ä»A£ÖLÄ<m ALKALMAS, T8Í \ZOL|4,S.ÜH*iRiMmtNT SZARMATA-KOI FAR Γ kt * t » H î'*î/ M MÎ ΓK Í*siM#p? i^vnj iKmíok L Gyógyászati készttmény, smegy a ItOvoífccwU'í tariakBasssstK: 5 '\(K- s\í tpvlk\ Κ*'*Ν »»"'i '>' iit N * s ' > ukkc smlb« mo s a V'! '' Ί< L ' k <* ο H -d|pírb«idb-KH)'-5'{2A!sLo>;iöíos!>-cík5o|;sx'íán'LA^sol;; t&amp;M&amp;ovageb amely mawil As k&amp;há?ts» kákm«»^í>sx5st*:Ua5Í^i k&amp;Öanyagok amely hkLosí-patpií-cdiHió?.; sgÉexesl eíosegiLl anyait amely 5sátAkm^kmériyi^|lskö;iS:yfe: egy vagy több keodai*yag«M. % &amp;£ t^ sglsypmkbsk maghaiiioesK gybgyferö kékaimény., sfeb 8:te^p|. ÄpMüii#«# ?s naRtum-utea* ko/ül vaktóatou. A Ai I. Vav.v 2. Igénypontban nvghsmfoacm gyoey&amp;sem; kcsakmêov, ahol a 1l‘H;«,é«, Jpí;S*;/b ) Sp1)-.; kí - Hí'* V+"4sbyorFemlKAloprs>pt?i"ant{!o}"5ApropHt«>j-OH' L^^-ânài'i'UH'LÎ-üjpÎnïîïi-iiî'i' <-íb-I UHK'os v ' u^i-i^UÍ A 's '!' '' 'CHS H''Ht ' ' ! ’ív«
  2. 4, As 1-3 igénypontok bármelyike szerű« megns-ározoö gyógyászait kuKzltmeïsy, ehoí a tAHbtmyag ·;ί-' -74 kVïÎiCg® « mennyiségben cais jeles.
  3. 5, Aï 1-4. Igénypernek bannelyik« sagiöi srsegbaKiro^üt· gyógyászai iömeg’A menny Aígker \,m jden.
  4. 6, Aï 1-1 igéssypuîbok ^ms?pte,'f^8k:5iö^bÄmÄMmimány, Mimi a s^RsFSl etoM&amp;itft anyag 2-ê ?ót«eg6á raensvvfsègie« mejßzu. ?. Aï 1-6. lg««ypontek bánvsely&amp;e seerim me;gha<:aröKeík gycígyáseet! kèmbmbny, almi a ke nyan va g 0Λ- - ; t<8neg*--> fnenayAsgbea vise je les. &amp; *\s \ 'gcrgfoesban snegînt«-v-m g\eg>^atj ke^crsneev, amely a kb veibe ,£ok;a teraaljmswk: ,0-45 UlmesH mem*\?φ&amp;* flS-H«. >m31XLS*2R .'{op*UioV-.>n- ',3 '>':-s\an|4 '-4jeemmbm Väb-m-gbsmbον tetőstt- ctKk>|xto^‘ ' 1"1:'!U-yy~4S tömegé menny «éghm masnitok ;0-3b iibseg'b mennyiségben belbiulsn kaKsomAbs:ao«vütl«i.inAoL 4-fi tí>m«g% m8noYKéglH'»litdí<txí|>f|S»Hceíhitó^,. '·$ tömatTA msftBvneghvm oúrnos«*pfetéayitö^tk<>l^töt5;.éS' A-áas iömeg'-A mentn ingben egy vagy tót<i> keaóasv&amp;giöt··· o g I w\ L íecnVixv'bm a c^ '< >o - ttu-A.s^ ' , ü\ '* 5 M a \o«oan^a^ ffi^pdbNt-' -sAïainb.
HUE07794121A 2006-08-21 2007-08-20 Orális adagolásra alkalmas, triazol[4,5-d]pirimidin származékot tartalmazó készítmények HUE031939T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82308306P 2006-08-21 2006-08-21

Publications (1)

Publication Number Publication Date
HUE031939T2 true HUE031939T2 (hu) 2017-08-28

Family

ID=39107049

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE07794121A HUE031939T2 (hu) 2006-08-21 2007-08-20 Orális adagolásra alkalmas, triazol[4,5-d]pirimidin származékot tartalmazó készítmények

Country Status (35)

Country Link
US (2) US8425934B2 (hu)
EP (1) EP2056832B1 (hu)
JP (2) JP5385139B2 (hu)
KR (1) KR101539467B1 (hu)
CN (1) CN101505754A (hu)
AR (1) AR062451A1 (hu)
AU (2) AU2007288541B9 (hu)
BR (1) BRPI0715712B8 (hu)
CA (1) CA2659328C (hu)
CL (1) CL2007002421A1 (hu)
CO (1) CO6150163A2 (hu)
CY (1) CY1119380T1 (hu)
DK (1) DK2056832T3 (hu)
ES (1) ES2625930T3 (hu)
HR (1) HRP20170694T1 (hu)
HU (1) HUE031939T2 (hu)
IL (2) IL196700A (hu)
LT (1) LT2056832T (hu)
MX (1) MX340403B (hu)
MY (2) MY175009A (hu)
NO (1) NO341787B1 (hu)
NZ (2) NZ574514A (hu)
PH (1) PH12013501627A1 (hu)
PL (1) PL2056832T3 (hu)
PT (1) PT2056832T (hu)
RS (1) RS55884B1 (hu)
RU (2) RU2476223C2 (hu)
SA (1) SA07280442B1 (hu)
SG (1) SG177162A1 (hu)
SI (1) SI2056832T1 (hu)
TW (1) TWI482772B (hu)
UA (1) UA99105C2 (hu)
UY (1) UY30551A1 (hu)
WO (1) WO2008024045A1 (hu)
ZA (1) ZA200900991B (hu)

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JP2019510785A (ja) 2016-04-08 2019-04-18 エックス4 ファーマシューティカルズ, インコーポレイテッド 癌を処置する方法
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CN101505754A (zh) 2009-08-12
KR20090055561A (ko) 2009-06-02
NZ596700A (en) 2013-05-31
WO2008024045A1 (en) 2008-02-28
MX2009001853A (es) 2009-03-02
KR101539467B1 (ko) 2015-07-24
IL229130A0 (en) 2013-12-31
MY147966A (en) 2013-02-28
SG177162A1 (en) 2012-01-30
DK2056832T3 (en) 2017-05-22
AU2007288541B9 (en) 2011-10-06
SA07280442B1 (ar) 2012-04-07
EP2056832B1 (en) 2017-03-22
MY175009A (en) 2020-06-02
US8425934B2 (en) 2013-04-23
PT2056832T (pt) 2017-05-22
CA2659328A1 (en) 2008-02-28
IL196700A (en) 2014-08-31
ES2625930T3 (es) 2017-07-21
NZ574514A (en) 2012-01-12
EP2056832A4 (en) 2012-12-26
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