HUE027990T2 - Karbosztiril-származék amin sója, amely alkalmas többek között gyomorfekély kezelésére - Google Patents
Karbosztiril-származék amin sója, amely alkalmas többek között gyomorfekély kezelésére Download PDFInfo
- Publication number
- HUE027990T2 HUE027990T2 HUE05704144A HUE05704144A HUE027990T2 HU E027990 T2 HUE027990 T2 HU E027990T2 HU E05704144 A HUE05704144 A HU E05704144A HU E05704144 A HUE05704144 A HU E05704144A HU E027990 T2 HUE027990 T2 HU E027990T2
- Authority
- HU
- Hungary
- Prior art keywords
- amine
- salt
- pharmaceutical composition
- amine salt
- derivative
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (4)
- Szabadalmi igénypoaioh1. Az (!) általáé« képieti vegyük szerinti karbosztin!-s#rmazék amin sójam ahol a képletben:: R jelentése isalogénatom, a kartaætàil vázon as oWalláec helyettesített pozíciója: a 3. vagy 4. pozíció, és a a. karboszílribváz 3. és 4. pozíciója. közötti kötés egyszeres vagy: kétszeres kötés, és egy eílléndiamin, tns^y'dmlajietijaátmometán, monoetanoiamin, dietanokmnn, d iizopropanokm in és megírna in köréből választott amin »
- 2, Az i. igénypont szerint! RÍtrbeszíirihszámmzék amin sója, ahol az (1). karboszttrlkszármazék 2-(4-klórbenzoiiannnn}--3-(2'-ki:mion-4-il}propionsav. 3, A 3. Igénypont szerinti karboszbtii-'Származék amin sósa, ahol az amin etlléttdiarmn. 4. A 2. igénypont szerinti: karöosztirii-szánpazék amin sója, ahol az amis trisz(kidrozimeti Ikminometán, 1A 2< igénypont szerinti: kas'bosztiríbszánnazék amin sója, aboi az amin monoeianolatom, 6. A 3.; igénypont szerinti karboszüril-szánnazék amin sója, almi az amin dietanolasnín. 7, A 2. Igénypont szedőt! karbosztlsik-szármnzék mm sója, ahol az amin diizópropanöiamm. 3. A 2:. Igénypont szerinti karimsztirll-származék amin sója, ahol az amin megírnom.
- 9. Az 1*8, igénypontok bármelyike szerinti k^rbosztirit-szarninzek ami«, sóját aktiv hatóanyagként tartalmazó gyógyászati kés/mnény. IÖ, Gyógyászati készítmény vizes oldat tormájában elkészítve, az (1) általános képleti vegyidet szerisál kazbosztiril-származéköt tartalmazó vizes oldószer hozzáadásávalIl jelentése Mfogénatom, a karbosztMl vázon: az oldaîlànc helyettesített pozíciója a 3, vagy 4. pozíció, és a karbösziinl-yáz 3. és 4, pozíciója közötti kotésogyszeres vagy kétszeres -kötés, is egv etlléndiamm, tász^í#o^imetil^mi«0£«eíá*i, nsonoeianolamin. djetanokmin, diízopropanokmin és meglnmm koréból választott ami«. IL A 1Ô. igénypont sprint elkészített gyógyászati.készítittéöy, ahol az (í) katböszíirik-származék 2-(4--kÍérbssízoila5«iö.ö}~3-(2-kií]oion~4---i!)pfopioasav; I2v A ! I. igénypont szerint elkészített gyógyászai! készítmény, ahol az amin eiiléndiaraia. 13. A 11. igénypont szerint elkészített gyógyászati készítmény, akoli az amin trisz(hidtt)ximeii1)aniittometán. 14. A. I I. igénypont szerint elkészített gyógyászati készítmény, ahol az mm monoetanotemiß.
- 15. A IL igénypont szerint elkészdett gyógyászati készítmény akoi az atamdisianolamin, l ó. A .11, Igénypont szerint elkészíteti gyógyászati készítmény,- ahol az amin- dlizopropanolarnln, 17, Ä 11. igénypont szerint elkészített gyógyászati készítmény ahol az amin meglumm
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004013402 | 2004-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE027990T2 true HUE027990T2 (hu) | 2016-11-28 |
Family
ID=34805383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE05704144A HUE027990T2 (hu) | 2004-01-21 | 2005-01-20 | Karbosztiril-származék amin sója, amely alkalmas többek között gyomorfekély kezelésére |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7732611B2 (hu) |
| EP (2) | EP2253619B1 (hu) |
| JP (1) | JP4516962B2 (hu) |
| KR (1) | KR100844762B1 (hu) |
| CN (1) | CN1934086B (hu) |
| AR (1) | AR047438A1 (hu) |
| AT (1) | ATE549318T1 (hu) |
| AU (1) | AU2005206430B2 (hu) |
| BR (1) | BRPI0506982A (hu) |
| CA (1) | CA2553231C (hu) |
| CY (2) | CY1112723T1 (hu) |
| DK (2) | DK2253619T3 (hu) |
| ES (2) | ES2544327T3 (hu) |
| HK (2) | HK1101327A1 (hu) |
| HU (1) | HUE027990T2 (hu) |
| MY (1) | MY148416A (hu) |
| PL (2) | PL2253619T3 (hu) |
| PT (2) | PT2253619E (hu) |
| RU (1) | RU2372336C2 (hu) |
| SG (1) | SG149854A1 (hu) |
| SI (2) | SI2253619T1 (hu) |
| TW (1) | TWI340650B (hu) |
| WO (1) | WO2005070892A1 (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187197B1 (en) * | 1998-10-28 | 2001-02-13 | Marvin Haddock | Multi-stage engine coolant recycling process |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| CN101778626B (zh) * | 2007-08-10 | 2014-05-07 | 大塚制药株式会社 | 含有瑞巴派特的药物组合物 |
| US9486418B2 (en) * | 2008-04-08 | 2016-11-08 | Dynamis Pharmaceuticals, Inc. | Method for treating or preventing dry eye disorders using alkylamino-polyhydroxyalkanes |
| CA2725487A1 (en) * | 2008-06-19 | 2009-12-23 | Otsuka Pharmaceutical Co., Ltd. | A pharmaceutical composition |
| US9248196B2 (en) | 2011-02-25 | 2016-02-02 | Nuformix Limited | Rebamipide complexes and cocrystals |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS517614Y2 (hu) | 1971-02-12 | 1976-03-01 | ||
| US4578381A (en) * | 1982-07-05 | 1986-03-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| JPS597168A (ja) | 1982-07-05 | 1984-01-14 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| EP0543018B1 (en) * | 1991-06-07 | 1996-01-10 | Otsuka Pharmaceutical Co., Ltd. | Antidiabetic agent |
| TW227558B (hu) * | 1992-05-14 | 1994-08-01 | Otsuka Pharma Co Ltd | |
| US5415872A (en) * | 1992-06-22 | 1995-05-16 | Digestive Care Inc. | Compositions of gastric acid-resistant microspheres containing salts of bile acids |
| JP2872546B2 (ja) * | 1992-11-26 | 1999-03-17 | 大塚製薬株式会社 | 腸粘膜障害保護剤 |
| DK0674515T3 (da) * | 1993-10-21 | 1999-12-20 | Otsuka Pharma Co Ltd | Anvendelse af carbostyrilderivater til fremstilling af et medikament til inhibering af interleukin-8 |
| AU8003194A (en) | 1993-11-05 | 1995-05-23 | Otsuka Pharmaceutical Co., Ltd. | Bismuth salt of carbostyril derivatives for the treatment of peptic ulcers |
| JP3621463B2 (ja) | 1995-04-26 | 2005-02-16 | 大塚製薬株式会社 | カルボスチリル誘導体ビスマス塩 |
| AR004214A1 (es) | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
| GB9613455D0 (en) | 1996-06-27 | 1996-08-28 | Aston Molecules Ltd | Analogues or derivatives of quercetin |
| TW200304813A (en) | 2002-03-11 | 2003-10-16 | Novartis Ag | Salts of organic acid |
| KR20040104020A (ko) | 2003-06-02 | 2004-12-10 | 진양제약주식회사 | 신규 레바미피드 리지네이트와 레바미피드 아르기니네이트및 이 신규 레바미피드 리지네이트와 레바미피드아르기니네이트를 유효성분으로 함유하는 약학적 제제 |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| JP4719917B2 (ja) | 2007-03-30 | 2011-07-06 | 国立大学法人 岡山大学 | アズキ加工食品のアズキ原料品種判定方法 |
-
2005
- 2005-01-18 TW TW094101386A patent/TWI340650B/zh not_active IP Right Cessation
- 2005-01-19 MY MYPI20050200A patent/MY148416A/en unknown
- 2005-01-20 KR KR1020067016600A patent/KR100844762B1/ko active IP Right Grant
- 2005-01-20 JP JP2006520510A patent/JP4516962B2/ja active Active
- 2005-01-20 HU HUE05704144A patent/HUE027990T2/hu unknown
- 2005-01-20 WO PCT/JP2005/001034 patent/WO2005070892A1/en active Application Filing
- 2005-01-20 EP EP10174397A patent/EP2253619B1/en not_active Not-in-force
- 2005-01-20 DK DK10174397.9T patent/DK2253619T3/da active
- 2005-01-20 SI SI200531494T patent/SI2253619T1/sl unknown
- 2005-01-20 AR ARP050100199A patent/AR047438A1/es not_active Application Discontinuation
- 2005-01-20 ES ES05704144.4T patent/ES2544327T3/es active Active
- 2005-01-20 US US10/586,453 patent/US7732611B2/en not_active Expired - Fee Related
- 2005-01-20 PT PT10174397T patent/PT2253619E/pt unknown
- 2005-01-20 RU RU2006129945/04A patent/RU2372336C2/ru not_active IP Right Cessation
- 2005-01-20 AU AU2005206430A patent/AU2005206430B2/en not_active Ceased
- 2005-01-20 BR BRPI0506982-3A patent/BRPI0506982A/pt not_active IP Right Cessation
- 2005-01-20 CN CN2005800086478A patent/CN1934086B/zh not_active Expired - Fee Related
- 2005-01-20 AT AT10174397T patent/ATE549318T1/de active
- 2005-01-20 CA CA2553231A patent/CA2553231C/en not_active Expired - Fee Related
- 2005-01-20 PL PL10174397T patent/PL2253619T3/pl unknown
- 2005-01-20 PT PT57041444T patent/PT1706383E/pt unknown
- 2005-01-20 SG SG200900369-0A patent/SG149854A1/en unknown
- 2005-01-20 DK DK05704144.4T patent/DK1706383T3/en active
- 2005-01-20 ES ES10174397T patent/ES2382133T3/es active Active
- 2005-01-20 EP EP05704144.4A patent/EP1706383B1/en not_active Not-in-force
- 2005-01-20 PL PL05704144T patent/PL1706383T3/pl unknown
- 2005-01-20 SI SI200531992T patent/SI1706383T1/sl unknown
-
2007
- 2007-08-24 HK HK07109247.5A patent/HK1101327A1/xx not_active IP Right Cessation
-
2010
- 2010-04-26 US US12/662,610 patent/US8222276B2/en not_active Expired - Fee Related
-
2011
- 2011-03-17 HK HK11102692.4A patent/HK1148527A1/xx not_active IP Right Cessation
-
2012
- 2012-05-11 CY CY20121100442T patent/CY1112723T1/el unknown
-
2015
- 2015-10-06 CY CY20151100891T patent/CY1116773T1/el unknown
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