BRPI0506982A - sal de amina de derivado de carboestirila - Google Patents
sal de amina de derivado de carboestirilaInfo
- Publication number
- BRPI0506982A BRPI0506982A BRPI0506982-3A BRPI0506982A BRPI0506982A BR PI0506982 A BRPI0506982 A BR PI0506982A BR PI0506982 A BRPI0506982 A BR PI0506982A BR PI0506982 A BRPI0506982 A BR PI0506982A
- Authority
- BR
- Brazil
- Prior art keywords
- carbostyril
- amine salt
- carbostyril derivative
- bond
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SAL DE AMINA DE DERIVADO DE CARBOESTIRILA. A invenção refere-se a um sal de amina de um derivado de carboestirila formado a partir de um derivado de carboestirila representado pela fórmula (1) ¢onde R é um átomo de halogênio: a posição substituída da cadeia lateral é a posição 3- ou 4- no esqueleto carboestirila; e a ligação entre as posições 3- e 4- do esqueleto carboestirila é uma ligação simples ou uma ligação dupla! e uma amina; e a invenção é útil como fármacos para tratamento de várias doenças, especialmente como formulações aquosas devido à solubilidade em água superior e aos efeitos farmacológicos superiores.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004013402 | 2004-01-21 | ||
| PCT/JP2005/001034 WO2005070892A1 (en) | 2004-01-21 | 2005-01-20 | Amine salt of carbostyril derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0506982A true BRPI0506982A (pt) | 2007-07-03 |
Family
ID=34805383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0506982-3A BRPI0506982A (pt) | 2004-01-21 | 2005-01-20 | sal de amina de derivado de carboestirila |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7732611B2 (pt) |
| EP (2) | EP1706383B1 (pt) |
| JP (1) | JP4516962B2 (pt) |
| KR (1) | KR100844762B1 (pt) |
| CN (1) | CN1934086B (pt) |
| AR (1) | AR047438A1 (pt) |
| AT (1) | ATE549318T1 (pt) |
| AU (1) | AU2005206430B2 (pt) |
| BR (1) | BRPI0506982A (pt) |
| CA (1) | CA2553231C (pt) |
| CY (2) | CY1112723T1 (pt) |
| DK (2) | DK2253619T3 (pt) |
| ES (2) | ES2544327T3 (pt) |
| HK (2) | HK1101327A1 (pt) |
| HU (1) | HUE027990T2 (pt) |
| MY (1) | MY148416A (pt) |
| PL (2) | PL2253619T3 (pt) |
| PT (2) | PT1706383E (pt) |
| RU (1) | RU2372336C2 (pt) |
| SG (1) | SG149854A1 (pt) |
| SI (2) | SI1706383T1 (pt) |
| TW (1) | TWI340650B (pt) |
| WO (1) | WO2005070892A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187197B1 (en) * | 1998-10-28 | 2001-02-13 | Marvin Haddock | Multi-stage engine coolant recycling process |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| WO2009022674A1 (en) * | 2007-08-10 | 2009-02-19 | Otsuka Pharmaceutical Co., Ltd. | Medical composition containing rebamipide |
| US9486418B2 (en) | 2008-04-08 | 2016-11-08 | Dynamis Pharmaceuticals, Inc. | Method for treating or preventing dry eye disorders using alkylamino-polyhydroxyalkanes |
| SI2285413T1 (sl) * | 2008-06-19 | 2012-09-28 | Otsuka Pharma Co Ltd | Farmacevtski sestavek |
| WO2012114317A1 (en) * | 2011-02-25 | 2012-08-30 | Nuformix Limited | Novel rebamipide complexes and cocrystals |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS517614Y2 (pt) | 1971-02-12 | 1976-03-01 | ||
| JPS597168A (ja) | 1982-07-05 | 1984-01-14 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| US4578381A (en) * | 1982-07-05 | 1986-03-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| DE69207560T2 (de) * | 1991-06-07 | 1996-06-27 | Otsuka Pharma Co Ltd | Antidiabetikum |
| TW227558B (pt) * | 1992-05-14 | 1994-08-01 | Otsuka Pharma Co Ltd | |
| US5415872A (en) * | 1992-06-22 | 1995-05-16 | Digestive Care Inc. | Compositions of gastric acid-resistant microspheres containing salts of bile acids |
| JP2872546B2 (ja) * | 1992-11-26 | 1999-03-17 | 大塚製薬株式会社 | 腸粘膜障害保護剤 |
| CN1073418C (zh) * | 1993-10-21 | 2001-10-24 | 大塚制药株式会社 | 白细胞介素－8生成抑制剂 |
| AU8003194A (en) | 1993-11-05 | 1995-05-23 | Otsuka Pharmaceutical Co., Ltd. | Bismuth salt of carbostyril derivatives for the treatment of peptic ulcers |
| JP3621463B2 (ja) * | 1995-04-26 | 2005-02-16 | 大塚製薬株式会社 | カルボスチリル誘導体ビスマス塩 |
| AR004214A1 (es) | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
| GB9613455D0 (en) | 1996-06-27 | 1996-08-28 | Aston Molecules Ltd | Analogues or derivatives of quercetin |
| CA2478599A1 (en) | 2002-03-11 | 2003-09-18 | Novartis Ag | Salts of nateglinide |
| KR20040104020A (ko) | 2003-06-02 | 2004-12-10 | 진양제약주식회사 | 신규 레바미피드 리지네이트와 레바미피드 아르기니네이트및 이 신규 레바미피드 리지네이트와 레바미피드아르기니네이트를 유효성분으로 함유하는 약학적 제제 |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| JP4719917B2 (ja) | 2007-03-30 | 2011-07-06 | 国立大学法人 岡山大学 | アズキ加工食品のアズキ原料品種判定方法 |
-
2005
- 2005-01-18 TW TW094101386A patent/TWI340650B/zh not_active IP Right Cessation
- 2005-01-19 MY MYPI20050200A patent/MY148416A/en unknown
- 2005-01-20 DK DK10174397.9T patent/DK2253619T3/da active
- 2005-01-20 PL PL10174397T patent/PL2253619T3/pl unknown
- 2005-01-20 CN CN2005800086478A patent/CN1934086B/zh not_active Expired - Fee Related
- 2005-01-20 JP JP2006520510A patent/JP4516962B2/ja active Active
- 2005-01-20 SG SG200900369-0A patent/SG149854A1/en unknown
- 2005-01-20 AU AU2005206430A patent/AU2005206430B2/en not_active Ceased
- 2005-01-20 HU HUE05704144A patent/HUE027990T2/en unknown
- 2005-01-20 PT PT57041444T patent/PT1706383E/pt unknown
- 2005-01-20 RU RU2006129945/04A patent/RU2372336C2/ru not_active IP Right Cessation
- 2005-01-20 US US10/586,453 patent/US7732611B2/en not_active Expired - Fee Related
- 2005-01-20 WO PCT/JP2005/001034 patent/WO2005070892A1/en active Application Filing
- 2005-01-20 AR ARP050100199A patent/AR047438A1/es not_active Application Discontinuation
- 2005-01-20 ES ES05704144.4T patent/ES2544327T3/es active Active
- 2005-01-20 BR BRPI0506982-3A patent/BRPI0506982A/pt not_active IP Right Cessation
- 2005-01-20 AT AT10174397T patent/ATE549318T1/de active
- 2005-01-20 PT PT10174397T patent/PT2253619E/pt unknown
- 2005-01-20 PL PL05704144T patent/PL1706383T3/pl unknown
- 2005-01-20 SI SI200531992T patent/SI1706383T1/sl unknown
- 2005-01-20 EP EP05704144.4A patent/EP1706383B1/en not_active Not-in-force
- 2005-01-20 CA CA2553231A patent/CA2553231C/en not_active Expired - Fee Related
- 2005-01-20 KR KR1020067016600A patent/KR100844762B1/ko active IP Right Grant
- 2005-01-20 SI SI200531494T patent/SI2253619T1/sl unknown
- 2005-01-20 DK DK05704144.4T patent/DK1706383T3/en active
- 2005-01-20 EP EP10174397A patent/EP2253619B1/en not_active Not-in-force
- 2005-01-20 ES ES10174397T patent/ES2382133T3/es active Active
-
2007
- 2007-08-24 HK HK07109247.5A patent/HK1101327A1/xx not_active IP Right Cessation
-
2010
- 2010-04-26 US US12/662,610 patent/US8222276B2/en not_active Expired - Fee Related
-
2011
- 2011-03-17 HK HK11102692.4A patent/HK1148527A1/xx not_active IP Right Cessation
-
2012
- 2012-05-11 CY CY20121100442T patent/CY1112723T1/el unknown
-
2015
- 2015-10-06 CY CY20151100891T patent/CY1116773T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |