ATE467632T1 - Pyrroloä2,3-büpyridinderivate als modulatoren des h3-rezeptors - Google Patents
Pyrroloä2,3-büpyridinderivate als modulatoren des h3-rezeptorsInfo
- Publication number
- ATE467632T1 ATE467632T1 AT06830424T AT06830424T ATE467632T1 AT E467632 T1 ATE467632 T1 AT E467632T1 AT 06830424 T AT06830424 T AT 06830424T AT 06830424 T AT06830424 T AT 06830424T AT E467632 T1 ATE467632 T1 AT E467632T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrroloä2
- büpyridine
- modulators
- receptor
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05112317 | 2005-12-16 | ||
PCT/EP2006/069390 WO2007068641A1 (en) | 2005-12-16 | 2006-12-06 | Pyrrolo [2 , 3-b] pyridine derivatives as h3 receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE467632T1 true ATE467632T1 (de) | 2010-05-15 |
Family
ID=37698129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06830424T ATE467632T1 (de) | 2005-12-16 | 2006-12-06 | Pyrroloä2,3-büpyridinderivate als modulatoren des h3-rezeptors |
Country Status (13)
Country | Link |
---|---|
US (1) | US7351708B2 (de) |
EP (1) | EP1971605B1 (de) |
JP (1) | JP2009519293A (de) |
KR (1) | KR101015666B1 (de) |
CN (1) | CN101331131A (de) |
AT (1) | ATE467632T1 (de) |
AU (1) | AU2006326067A1 (de) |
BR (1) | BRPI0619985A2 (de) |
CA (1) | CA2631695A1 (de) |
DE (1) | DE602006014305D1 (de) |
ES (1) | ES2344077T3 (de) |
IL (1) | IL191763A0 (de) |
WO (1) | WO2007068641A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
AR074466A1 (es) | 2008-12-05 | 2011-01-19 | Sanofi Aventis | Piperidina espiro pirrolidinona y piperidinona sustituidas y su uso terapeutico en enfermedades mediadas por la modulacion de los receptores h3. |
AR074467A1 (es) | 2008-12-05 | 2011-01-19 | Sanofi Aventis | Tetrahidropiran espiro pirrolidinonas y piperidinonas sustituidas, composiciones farmaceuticas que las contienen y uso de las mismas en el tratamiento y/o prevencion de enfermedades del snc ,tales como alzheimer y parkinson, entre otras. |
US8222416B2 (en) * | 2009-12-14 | 2012-07-17 | Hoffmann-La Roche Inc. | Azaindole glucokinase activators |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
CN102952139B (zh) * | 2011-08-30 | 2016-08-10 | 上海药明康德新药开发有限公司 | 反式-3a-氟吡咯烷[3,4-C]并环化合物及其制备方法 |
CN105492008B (zh) | 2013-03-13 | 2020-11-27 | 福马治疗股份有限公司 | 用于抑制fasn的化合物及组合物 |
KR102161787B1 (ko) * | 2018-07-02 | 2020-10-06 | 한국기초과학지원연구원 | 수면 장애의 예방 또는 치료용 약학적 조성물 |
TWI767148B (zh) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | 抑制脂肪酸合成酶(fasn) |
US10793554B2 (en) | 2018-10-29 | 2020-10-06 | Forma Therapeutics, Inc. | Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1247547A (en) | 1983-06-22 | 1988-12-28 | Paul Hadvary | Leucine derivatives |
CA1328881C (en) | 1984-12-21 | 1994-04-26 | Pierre Barbier | Process for the manufacture of oxetanones |
US5246960A (en) | 1984-12-21 | 1993-09-21 | Hoffmann-La Roche Inc. | Oxetanones |
CA1270837A (en) | 1984-12-21 | 1990-06-26 | Hoffmann-La Roche Limited | Oxetanones |
CA2035972C (en) | 1990-02-23 | 2006-07-11 | Martin Karpf | Process for the preparation of oxetanones |
US5274143A (en) | 1991-07-23 | 1993-12-28 | Hoffmann-La Roche Inc. | Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione |
US6004996A (en) | 1997-02-05 | 1999-12-21 | Hoffman-La Roche Inc. | Tetrahydrolipstatin containing compositions |
US6267952B1 (en) | 1998-01-09 | 2001-07-31 | Geltex Pharmaceuticals, Inc. | Lipase inhibiting polymers |
PT1105122E (pt) | 1998-08-14 | 2005-08-31 | Hoffmann La Roche | Composicoes farmaceuticas que contem inibidores de lipase |
AU759388B2 (en) | 1998-08-14 | 2003-04-10 | Cheplapharm Arzneimittel Gmbh | Pharmaceutical compositions containing lipase inhibitors and chitosan |
GB9902047D0 (en) | 1999-01-29 | 1999-03-17 | Cerebrus Ltd | Chemical compounds XI |
GB0202015D0 (en) | 2002-01-29 | 2002-03-13 | Hoffmann La Roche | Piperazine Derivatives |
CN1713910A (zh) | 2002-10-09 | 2005-12-28 | 西奥斯股份有限公司 | 作为p38激酶抑制剂的氮杂吲哚衍生物 |
GB0224084D0 (en) * | 2002-10-16 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
MXPA05012547A (es) | 2003-05-21 | 2006-05-25 | Prosidion Ltd | Inhibidores de amida de acido pirrolopiridina-2-carboxilico de fosforilasa de glucogeno. |
DE602005018758D1 (de) | 2004-04-01 | 2010-02-25 | Lilly Co Eli | Am histamin-h3-rezeptor wirksame mittel, herstellung und therapeutische anwendungen |
-
2006
- 2006-12-06 AT AT06830424T patent/ATE467632T1/de active
- 2006-12-06 KR KR1020087014335A patent/KR101015666B1/ko not_active IP Right Cessation
- 2006-12-06 JP JP2008544966A patent/JP2009519293A/ja active Pending
- 2006-12-06 WO PCT/EP2006/069390 patent/WO2007068641A1/en active Application Filing
- 2006-12-06 CN CNA2006800474567A patent/CN101331131A/zh active Pending
- 2006-12-06 BR BRPI0619985-2A patent/BRPI0619985A2/pt not_active IP Right Cessation
- 2006-12-06 ES ES06830424T patent/ES2344077T3/es active Active
- 2006-12-06 US US11/634,563 patent/US7351708B2/en not_active Expired - Fee Related
- 2006-12-06 EP EP06830424A patent/EP1971605B1/de not_active Not-in-force
- 2006-12-06 CA CA002631695A patent/CA2631695A1/en not_active Abandoned
- 2006-12-06 AU AU2006326067A patent/AU2006326067A1/en not_active Abandoned
- 2006-12-06 DE DE602006014305T patent/DE602006014305D1/de active Active
-
2008
- 2008-05-27 IL IL191763A patent/IL191763A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0619985A2 (pt) | 2011-10-25 |
JP2009519293A (ja) | 2009-05-14 |
KR101015666B1 (ko) | 2011-02-22 |
US20070142358A1 (en) | 2007-06-21 |
CN101331131A (zh) | 2008-12-24 |
ES2344077T3 (es) | 2010-08-17 |
IL191763A0 (en) | 2008-12-29 |
CA2631695A1 (en) | 2007-06-21 |
US7351708B2 (en) | 2008-04-01 |
KR20080068132A (ko) | 2008-07-22 |
EP1971605A1 (de) | 2008-09-24 |
AU2006326067A1 (en) | 2007-06-21 |
WO2007068641A1 (en) | 2007-06-21 |
EP1971605B1 (de) | 2010-05-12 |
DE602006014305D1 (de) | 2010-06-24 |
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UEP | Publication of translation of european patent specification |
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