ATE495159T1 - Diaminocyclohexan- und diaminocyclopentanderivate - Google Patents

Diaminocyclohexan- und diaminocyclopentanderivate

Info

Publication number
ATE495159T1
ATE495159T1 AT07847222T AT07847222T ATE495159T1 AT E495159 T1 ATE495159 T1 AT E495159T1 AT 07847222 T AT07847222 T AT 07847222T AT 07847222 T AT07847222 T AT 07847222T AT E495159 T1 ATE495159 T1 AT E495159T1
Authority
AT
Austria
Prior art keywords
diaminocyclopenete
diaminocyclohexane
derivatives
compounds
hyperphagia
Prior art date
Application number
AT07847222T
Other languages
English (en)
Inventor
Shawn David Erickson
Yimin Qian
Jefferson Wright Tilley
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE495159T1 publication Critical patent/ATE495159T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyamides (AREA)
AT07847222T 2006-11-30 2007-11-20 Diaminocyclohexan- und diaminocyclopentanderivate ATE495159T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86186706P 2006-11-30 2006-11-30
PCT/EP2007/062535 WO2008065021A1 (en) 2006-11-30 2007-11-20 Diaminocyclohexane and diaminocyclopentane derivatives

Publications (1)

Publication Number Publication Date
ATE495159T1 true ATE495159T1 (de) 2011-01-15

Family

ID=39048006

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07847222T ATE495159T1 (de) 2006-11-30 2007-11-20 Diaminocyclohexan- und diaminocyclopentanderivate

Country Status (9)

Country Link
US (1) US7652053B2 (de)
EP (1) EP2089368B1 (de)
JP (1) JP5122579B2 (de)
CN (1) CN101541760B (de)
AT (1) ATE495159T1 (de)
CA (1) CA2670573A1 (de)
DE (1) DE602007011971D1 (de)
ES (1) ES2357454T3 (de)
WO (1) WO2008065021A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100130737A1 (en) * 2005-02-18 2010-05-27 Takeda Pharmaceutical Company Limited Regulating Agent of GPR34 Receptor Function
US8461328B2 (en) 2010-01-12 2013-06-11 Genentech, Inc. Tricyclic heterocyclic compounds, compositions and methods of use thereof
WO2013007768A1 (en) 2011-07-13 2013-01-17 F. Hoffmann-La Roche Ag Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
US20140249105A1 (en) 2011-07-25 2014-09-04 Diverchim Novel ceramide analogues, processes for preparing same and uses thereof
GB201308236D0 (en) 2013-05-08 2013-06-12 Givaudan Sa Improvements in or relating to organic compounds
WO2014205782A1 (en) 2013-06-28 2014-12-31 Givaudan Sa Organic compounds
JP6491748B2 (ja) 2014-11-10 2019-03-27 ジボダン エス エー 有機化合物におけるまたは関連する改善
CN117486758B (zh) * 2023-10-30 2025-12-26 南京正济医药研究有限公司 一种(1s,3s)-3-氨基环戊基氨基甲酸叔丁酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI973176L (fi) * 1995-02-01 1997-07-31 Upjohn Co Selektiivisinä dopamiini-D3-ligandeina toimivia 2-aminoindaaneja
US6291499B1 (en) * 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US7160879B2 (en) 2002-01-10 2007-01-09 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 2-(4-benzyl-piperazin-1-ylmethyl)- and 2-(4-benzyl-diazepan-1-ylmethyl)-1H-benzoimidazole analogues
WO2004031177A1 (ja) 2002-09-30 2004-04-15 Banyu Pharmaceutical Co., Ltd. 2−アミノベンズイミダゾール誘導体
AU2006298852A1 (en) 2005-09-30 2007-04-12 F. Hoffmann-La Roche Ag Indane derivatives as MCH receptor antagonists

Also Published As

Publication number Publication date
ES2357454T3 (es) 2011-04-26
US7652053B2 (en) 2010-01-26
JP2010511007A (ja) 2010-04-08
CA2670573A1 (en) 2008-06-05
EP2089368A1 (de) 2009-08-19
CN101541760B (zh) 2012-02-08
EP2089368B1 (de) 2011-01-12
JP5122579B2 (ja) 2013-01-16
DE602007011971D1 (de) 2011-02-24
WO2008065021A1 (en) 2008-06-05
CN101541760A (zh) 2009-09-23
US20080146636A1 (en) 2008-06-19

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties