ATE495159T1 - Diaminocyclohexan- und diaminocyclopentanderivate - Google Patents

Diaminocyclohexan- und diaminocyclopentanderivate

Info

Publication number
ATE495159T1
ATE495159T1 AT07847222T AT07847222T ATE495159T1 AT E495159 T1 ATE495159 T1 AT E495159T1 AT 07847222 T AT07847222 T AT 07847222T AT 07847222 T AT07847222 T AT 07847222T AT E495159 T1 ATE495159 T1 AT E495159T1
Authority
AT
Austria
Prior art keywords
diaminocyclopenete
diaminocyclohexane
derivatives
compounds
hyperphagia
Prior art date
Application number
AT07847222T
Other languages
English (en)
Inventor
Shawn David Erickson
Yimin Qian
Jefferson Wright Tilley
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE495159T1 publication Critical patent/ATE495159T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT07847222T 2006-11-30 2007-11-20 Diaminocyclohexan- und diaminocyclopentanderivate ATE495159T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86186706P 2006-11-30 2006-11-30
PCT/EP2007/062535 WO2008065021A1 (en) 2006-11-30 2007-11-20 Diaminocyclohexane and diaminocyclopentane derivatives

Publications (1)

Publication Number Publication Date
ATE495159T1 true ATE495159T1 (de) 2011-01-15

Family

ID=39048006

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07847222T ATE495159T1 (de) 2006-11-30 2007-11-20 Diaminocyclohexan- und diaminocyclopentanderivate

Country Status (9)

Country Link
US (1) US7652053B2 (de)
EP (1) EP2089368B1 (de)
JP (1) JP5122579B2 (de)
CN (1) CN101541760B (de)
AT (1) ATE495159T1 (de)
CA (1) CA2670573A1 (de)
DE (1) DE602007011971D1 (de)
ES (1) ES2357454T3 (de)
WO (1) WO2008065021A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2006088246A1 (ja) * 2005-02-18 2008-07-10 武田薬品工業株式会社 Ｇｐｒ３４受容体機能調節剤
WO2011086053A1 (en) 2010-01-12 2011-07-21 F. Hoffmann-La Roche Ag Tricyclic heterocyclic compounds, compositions and methods of use thereof
WO2013007768A1 (en) 2011-07-13 2013-01-17 F. Hoffmann-La Roche Ag Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
US20140249105A1 (en) 2011-07-25 2014-09-04 Diverchim Novel ceramide analogues, processes for preparing same and uses thereof
GB201308236D0 (en) * 2013-05-08 2013-06-12 Givaudan Sa Improvements in or relating to organic compounds
WO2014205782A1 (en) 2013-06-28 2014-12-31 Givaudan Sa Organic compounds
JP6491748B2 (ja) 2014-11-10 2019-03-27 ジボダン エス エー 有機化合物におけるまたは関連する改善
CN117486758B (zh) * 2023-10-30 2025-12-26 南京正济医药研究有限公司 一种(1s,3s)-3-氨基环戊基氨基甲酸叔丁酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT807101E (pt) * 1995-02-01 2001-12-28 Upjohn Co 2-aminoindanos comoligandos selectivos de dopamina d3
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
EP1465635A4 (de) 2002-01-10 2005-04-13 Neurogen Corp Melanin-konzentrierende hormonrezeptor-liganden: substituierte 2-(4-benzyl-piperazin-1-ylmethyl)- und 2-(4-benzyl-diazepan-1-ylmethyl)-1h-benzoimidazol-analoga
AU2003266668A1 (en) 2002-09-30 2004-04-23 Banyu Pharmaceutical Co., Ltd. 2-aminobenzimidazole derivative
WO2007039462A2 (en) 2005-09-30 2007-04-12 F. Hoffmann-La Roche Ag Indane derivatives as mch receptor antagonists

Also Published As

Publication number Publication date
JP2010511007A (ja) 2010-04-08
US7652053B2 (en) 2010-01-26
CN101541760A (zh) 2009-09-23
CN101541760B (zh) 2012-02-08
EP2089368A1 (de) 2009-08-19
US20080146636A1 (en) 2008-06-19
DE602007011971D1 (de) 2011-02-24
WO2008065021A1 (en) 2008-06-05
CA2670573A1 (en) 2008-06-05
EP2089368B1 (de) 2011-01-12
ES2357454T3 (es) 2011-04-26
JP5122579B2 (ja) 2013-01-16

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Legal Events

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