CY1116773T1 - Αλας αμινης καρβοστυριλ παραγωγου - Google Patents
Αλας αμινης καρβοστυριλ παραγωγουInfo
- Publication number
- CY1116773T1 CY1116773T1 CY20151100891T CY151100891T CY1116773T1 CY 1116773 T1 CY1116773 T1 CY 1116773T1 CY 20151100891 T CY20151100891 T CY 20151100891T CY 151100891 T CY151100891 T CY 151100891T CY 1116773 T1 CY1116773 T1 CY 1116773T1
- Authority
- CY
- Cyprus
- Prior art keywords
- carbostyril
- producer
- amine
- carbostyryl
- bond
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Η εφεύρεση παρέχει άλας αμίνης ενός καρβοστυρίλ παραγώγου που σχηματίζεται από καρβοστυρίλ παράγωγο που αντιπροσωπεύεται με τον τύπο (1) [όπου R είναι άτομο αλογόνου- η υποκατεστημένη θέση της πλευρικής αλύσου είναι η 3- ή 4-θέση στον καρβοστυρίλ σκελετό και ο δεσμός μεταξύ 3- και 4-θέσων του καρβοστυρίλ σκελετού είναι απλός δεσμός ή διπλός δεσμός] και μια αμίνη και η εφεύρεση είναι χρήσιμη ως φάρμακο για την θεραπεία διαφόρων ασθενειών, ειδικώς ως υδατική συνταγοποίηση, λόγω της ανώτερης διαλυτότητας στο νερό και των ανωτέρων φαρμακολογικών αποτελεσμάτων.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004013402 | 2004-01-21 | ||
| EP05704144.4A EP1706383B1 (en) | 2004-01-21 | 2005-01-20 | Amine salt of carbostyril derivative useful for the treatment of, inter alia, gastric ulcer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1116773T1 true CY1116773T1 (el) | 2017-03-15 |
Family
ID=34805383
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100442T CY1112723T1 (el) | 2004-01-21 | 2012-05-11 | Αλας αμινης καρβοστυριλ παραγωγου |
| CY20151100891T CY1116773T1 (el) | 2004-01-21 | 2015-10-06 | Αλας αμινης καρβοστυριλ παραγωγου |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100442T CY1112723T1 (el) | 2004-01-21 | 2012-05-11 | Αλας αμινης καρβοστυριλ παραγωγου |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7732611B2 (el) |
| EP (2) | EP1706383B1 (el) |
| JP (1) | JP4516962B2 (el) |
| KR (1) | KR100844762B1 (el) |
| CN (1) | CN1934086B (el) |
| AR (1) | AR047438A1 (el) |
| AT (1) | ATE549318T1 (el) |
| AU (1) | AU2005206430B2 (el) |
| BR (1) | BRPI0506982A (el) |
| CA (1) | CA2553231C (el) |
| CY (2) | CY1112723T1 (el) |
| DK (2) | DK2253619T3 (el) |
| ES (2) | ES2544327T3 (el) |
| HK (2) | HK1101327A1 (el) |
| HU (1) | HUE027990T2 (el) |
| MY (1) | MY148416A (el) |
| PL (2) | PL1706383T3 (el) |
| PT (2) | PT1706383E (el) |
| RU (1) | RU2372336C2 (el) |
| SG (1) | SG149854A1 (el) |
| SI (2) | SI2253619T1 (el) |
| TW (1) | TWI340650B (el) |
| WO (1) | WO2005070892A1 (el) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187197B1 (en) * | 1998-10-28 | 2001-02-13 | Marvin Haddock | Multi-stage engine coolant recycling process |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| MY157582A (en) * | 2007-08-10 | 2016-06-30 | Otsuka Pharma Co Ltd | Medical composition containing rebamipipe |
| WO2009126695A2 (en) | 2008-04-08 | 2009-10-15 | Dynamis Therapeutics, Inc. | Method for treating or preventing dry eye disorders using alkylamino-polyhydroxyalkanes |
| AU2009261101B2 (en) * | 2008-06-19 | 2013-11-07 | Otsuka Pharmaceutical Co., Ltd. | A pharmaceutical composition comprising rebamipide |
| CN103476753B (zh) * | 2011-02-25 | 2015-12-09 | 诺弗米克斯有限公司 | 新的瑞巴派特复合物和共晶体 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS517614Y2 (el) | 1971-02-12 | 1976-03-01 | ||
| JPS597168A (ja) | 1982-07-05 | 1984-01-14 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| FI80022C (fi) * | 1982-07-05 | 1990-04-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat. |
| DE69207560T2 (de) * | 1991-06-07 | 1996-06-27 | Otsuka Pharma Co Ltd | Antidiabetikum |
| TW227558B (el) * | 1992-05-14 | 1994-08-01 | Otsuka Pharma Co Ltd | |
| US5415872A (en) * | 1992-06-22 | 1995-05-16 | Digestive Care Inc. | Compositions of gastric acid-resistant microspheres containing salts of bile acids |
| JP2872546B2 (ja) * | 1992-11-26 | 1999-03-17 | 大塚製薬株式会社 | 腸粘膜障害保護剤 |
| WO1995011026A1 (en) * | 1993-10-21 | 1995-04-27 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative for inhibiting production of interleukin-8 |
| WO1995012579A1 (en) | 1993-11-05 | 1995-05-11 | Otsuka Pharmaceutical Company, Limited | Bismuth salt of carbostyril derivatives for the treatment of peptic ulcers |
| JP3621463B2 (ja) | 1995-04-26 | 2005-02-16 | 大塚製薬株式会社 | カルボスチリル誘導体ビスマス塩 |
| AR004214A1 (es) * | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
| GB9613455D0 (en) | 1996-06-27 | 1996-08-28 | Aston Molecules Ltd | Analogues or derivatives of quercetin |
| EP1483232A1 (en) | 2002-03-11 | 2004-12-08 | Novartis AG | Salts of nateglinide |
| KR20040104020A (ko) | 2003-06-02 | 2004-12-10 | 진양제약주식회사 | 신규 레바미피드 리지네이트와 레바미피드 아르기니네이트및 이 신규 레바미피드 리지네이트와 레바미피드아르기니네이트를 유효성분으로 함유하는 약학적 제제 |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| JP4719917B2 (ja) | 2007-03-30 | 2011-07-06 | 国立大学法人 岡山大学 | アズキ加工食品のアズキ原料品種判定方法 |
-
2005
- 2005-01-18 TW TW094101386A patent/TWI340650B/zh not_active IP Right Cessation
- 2005-01-19 MY MYPI20050200A patent/MY148416A/en unknown
- 2005-01-20 JP JP2006520510A patent/JP4516962B2/ja active Active
- 2005-01-20 CN CN2005800086478A patent/CN1934086B/zh not_active Expired - Fee Related
- 2005-01-20 PL PL05704144T patent/PL1706383T3/pl unknown
- 2005-01-20 KR KR1020067016600A patent/KR100844762B1/ko active IP Right Grant
- 2005-01-20 PT PT57041444T patent/PT1706383E/pt unknown
- 2005-01-20 PL PL10174397T patent/PL2253619T3/pl unknown
- 2005-01-20 EP EP05704144.4A patent/EP1706383B1/en not_active Not-in-force
- 2005-01-20 ES ES05704144.4T patent/ES2544327T3/es active Active
- 2005-01-20 AU AU2005206430A patent/AU2005206430B2/en not_active Ceased
- 2005-01-20 HU HUE05704144A patent/HUE027990T2/en unknown
- 2005-01-20 EP EP10174397A patent/EP2253619B1/en not_active Not-in-force
- 2005-01-20 BR BRPI0506982-3A patent/BRPI0506982A/pt not_active IP Right Cessation
- 2005-01-20 RU RU2006129945/04A patent/RU2372336C2/ru not_active IP Right Cessation
- 2005-01-20 US US10/586,453 patent/US7732611B2/en not_active Expired - Fee Related
- 2005-01-20 SI SI200531494T patent/SI2253619T1/sl unknown
- 2005-01-20 SG SG200900369-0A patent/SG149854A1/en unknown
- 2005-01-20 SI SI200531992T patent/SI1706383T1/sl unknown
- 2005-01-20 PT PT10174397T patent/PT2253619E/pt unknown
- 2005-01-20 AT AT10174397T patent/ATE549318T1/de active
- 2005-01-20 DK DK10174397.9T patent/DK2253619T3/da active
- 2005-01-20 DK DK05704144.4T patent/DK1706383T3/en active
- 2005-01-20 ES ES10174397T patent/ES2382133T3/es active Active
- 2005-01-20 CA CA2553231A patent/CA2553231C/en not_active Expired - Fee Related
- 2005-01-20 AR ARP050100199A patent/AR047438A1/es not_active Application Discontinuation
- 2005-01-20 WO PCT/JP2005/001034 patent/WO2005070892A1/en active Application Filing
-
2007
- 2007-08-24 HK HK07109247.5A patent/HK1101327A1/xx not_active IP Right Cessation
-
2010
- 2010-04-26 US US12/662,610 patent/US8222276B2/en not_active Expired - Fee Related
-
2011
- 2011-03-17 HK HK11102692.4A patent/HK1148527A1/xx not_active IP Right Cessation
-
2012
- 2012-05-11 CY CY20121100442T patent/CY1112723T1/el unknown
-
2015
- 2015-10-06 CY CY20151100891T patent/CY1116773T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1116773T1 (el) | Αλας αμινης καρβοστυριλ παραγωγου | |
| CY1120081T1 (el) | Παραγωγα hydroxybenzamide σαν παραγοντες καταστολης της hsp90 | |
| CY1109677T1 (el) | Παραγωγα κινολινης και χρηση αυτων ως μυκοβακτηριακων αναστολεων | |
| CY1119971T1 (el) | Αναστολεις gsk-3 | |
| CY1117157T1 (el) | Υποκατεστημενο παραγωγο ισοκινολινης | |
| CY1121543T1 (el) | Ενωση πυριδυλαμινοοξεικου οξεος | |
| CY1107426T1 (el) | Νεα παραγωγα φθοριογλυκοσιδιων απο πυραζολες, φαρμακευτικα προϊοντα που περιεχουν τις εν λογω ενωσεις και η χρηση αυτων | |
| CY1118390T1 (el) | Θεραπευτικος παραγων για τη φλεγμονωδη νοσο του εντερου | |
| CY1117319T1 (el) | Τρικυκλικα παραγωγα αμινης ως αναστολεις πρωτεϊνικης τυροσινης κινασης | |
| CY1113257T1 (el) | Παραγωγα βενζυλοπιπεραζινης τα οποια ειναι χρησιμα στη θεραπεια γαστρεντερικων διαταραχων | |
| CY1117078T1 (el) | Παραγωγα 1-((5-ετεροαρυλθειαζολ-2-υλ) αμινοκαρβονυλ) πυρρολιδινο-2-καρβοξαμιδης ως αναστολεις φωσφατιδυλινοσιτολ 3-κινασης (ρι3κ) χρησιμα στη θεραπεια πολλαπλασιαστικων νοσων | |
| CY1114452T1 (el) | Ενωσεις πυρρολιου | |
| CY1111425T1 (el) | ΠΑΡΑΓΩΓΑ ΤΗΣ ΠΥΡΙΔΟ[2,1-a]-ΙΣΟΚΙΝΟΛΙΝΗΣ ΩΣ DPP-IV ΑΝΑΣΤΟΛΕΙΣ | |
| CY1113324T1 (el) | Υποκατεστημενα αμιδικα παραγωγα ως αναστολεις πρωτεϊνικων κινασων | |
| ATE478044T1 (de) | Biphenylderivate und ihre verwendung bei der behandlung von hepatitis c | |
| CY1113029T1 (el) | Παραγωγα αζαδικυκλο [3.1.0] εξανιου χρησιμα ως ρυθμιστες υποδοχεων d3 ντοπαμινης | |
| CY1111876T1 (el) | Νεες πυρρολες με υπολiπiδaiμiκες και υποχοληστερολαιμικες δραστικοτητες, μεθοδος για την παρασκευη αυτων και φαρμακευτικες συνθεσεις που τις περιεχουν και η χρηση αυτων στην ιατρικη | |
| CY1109227T1 (el) | Παραγωγα της 5-φαινυλο-4-μεθυλο-θειαζολ-2-υλ-αμινης ως αναστολεις των ενζυμων κινασης της φωσφατιδυλινοσιτολης 3 (p13) για την θεραπεια των φλεγμονωδων ασθενειων των αεραγωγων | |
| CY1113504T1 (el) | Παραγωγο προπανο-1,3-διονης ή αλας αυτου | |
| CY1105621T1 (el) | Νεα ετεροκυκλικα παραγωγα φθορογλυκοζιτου, φαρμακα που περιεχουν τις ενωσεις αυτες και η χρηση τους | |
| CY1110520T1 (el) | Παραγωγα 5-υποκατεστημενης κινολινης και ισοκινολινης· μεθοδος για την παραγωγη τους και η χρηση τους ως αντιφλεγμονωδη | |
| ATE449776T1 (de) | Pyrroloä2,3-cüpyridinderivate | |
| CY1108246T1 (el) | ΠΑΡΑΓΩΓΑ 1Η-ΘΕΙΕΝΟ[2,3-c] ΠΥΡΑΖΟΛΗΣ ΧΡΗΣΙΜΑ ΩΣ ΑΝΑΣΤΟΛΕΙΣ ΚΙΝΑΣΗΣ | |
| EA200600621A1 (ru) | Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств | |
| MXPA05013474A (es) | Derivados de quinolilamida como antagonistas de ccr-5. |