HUE027546T2 - Hydantoin derivatives as cell necrosis inhibitors - Google Patents

Info

Publication number

HUE027546T2

HUE027546T2 HUE10011481A HUE10011481A HUE027546T2 HU E027546 T2 HUE027546 T2 HU E027546T2 HU E10011481 A HUE10011481 A HU E10011481A HU E10011481 A HUE10011481 A HU E10011481A HU E027546 T2 HUE027546 T2 HU E027546T2

Authority

HU

Hungary

Prior art keywords

alkyl

carbon atoms

carbons

virus

compound

Prior art date

2003-08-29

Links

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• 239000003112 inhibitor Substances 0.000 title claims description 40
• 230000017074 necrotic cell death Effects 0.000 title abstract description 36
• 150000001469 hydantoins Chemical class 0.000 title description 5
• 229940053195 antiepileptics hydantoin derivative Drugs 0.000 title description 2
• 150000001875 compounds Chemical class 0.000 claims abstract description 237
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• 229910052731 fluorine Inorganic materials 0.000 claims description 51
• 239000003795 chemical substances by application Substances 0.000 claims description 50
• 208000015181 infectious disease Diseases 0.000 claims description 50
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• 241000282414 Homo sapiens Species 0.000 claims description 40
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• 125000004432 carbon atom Chemical group C* 0.000 claims description 31
• 229910052757 nitrogen Inorganic materials 0.000 claims description 31
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• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
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