HUE027350T2 - Expressziós rendszer - Google Patents
Expressziós rendszer Download PDFInfo
- Publication number
- HUE027350T2 HUE027350T2 HUE13191424A HUE13191424A HUE027350T2 HU E027350 T2 HUE027350 T2 HU E027350T2 HU E13191424 A HUE13191424 A HU E13191424A HU E13191424 A HUE13191424 A HU E13191424A HU E027350 T2 HUE027350 T2 HU E027350T2
- Authority
- HU
- Hungary
- Prior art keywords
- vector
- expression
- host cell
- promoter
- expression system
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0602173.7A GB0602173D0 (en) | 2006-02-03 | 2006-02-03 | Expression system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE027350T2 true HUE027350T2 (hu) | 2016-09-28 |
Family
ID=36100973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE13191424A HUE027350T2 (hu) | 2006-02-03 | 2007-02-01 | Expressziós rendszer |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8530188B2 (https=) |
| EP (6) | EP1984506B1 (https=) |
| JP (5) | JP5221385B2 (https=) |
| KR (3) | KR101624345B1 (https=) |
| CN (3) | CN102690834B (https=) |
| CA (2) | CA2959915C (https=) |
| DK (4) | DK2695943T3 (https=) |
| ES (3) | ES2569075T3 (https=) |
| GB (1) | GB0602173D0 (https=) |
| HU (1) | HUE027350T2 (https=) |
| PL (3) | PL2695943T3 (https=) |
| PT (2) | PT1984506E (https=) |
| SG (3) | SG169390A1 (https=) |
| WO (1) | WO2007088371A2 (https=) |
| ZA (2) | ZA200806238B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0602173D0 (en) * | 2006-02-03 | 2006-03-15 | Avecia Ltd | Expression system |
| GB0709061D0 (en) * | 2007-05-11 | 2007-06-20 | Avecia Biolog Ltd | Expression system |
| GB0810154D0 (en) | 2008-06-04 | 2008-07-09 | Avecia Biolog Ltd | Expression vector |
| GB0905331D0 (en) * | 2009-03-27 | 2009-05-13 | Avecia Biolog Ltd | Expression process |
| GB201018664D0 (en) | 2010-11-05 | 2010-12-22 | Msd Biolog Uk Ltd | Expression process |
| GB201021795D0 (en) * | 2010-12-21 | 2011-02-02 | Msd Biolog Uk Ltd | Expression Process |
| GB201209896D0 (en) | 2012-06-01 | 2012-07-18 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process |
| TW201514193A (zh) | 2013-01-31 | 2015-04-16 | Glaxo Group Ltd | 製備蛋白質之方法 |
| US9873891B2 (en) * | 2013-05-03 | 2018-01-23 | Fujifilm Diosynth Biotechnologies Uk Limited | Expression process |
| GB201311837D0 (en) | 2013-07-01 | 2013-08-14 | Fujifilm Diosynth Biotechnologies Uk Ltd | Expression Process |
| GB201319930D0 (en) | 2013-11-12 | 2013-12-25 | Fujifilm Diosynth Biotechnologies Uk Ltd | Expression process |
| JP6803328B2 (ja) * | 2014-08-28 | 2021-01-06 | シンセティック バイオロジクス，インコーポレイテッド | 大腸菌ベースでのベータラクタマーゼ生産 |
| US9791697B2 (en) | 2015-12-11 | 2017-10-17 | Panasonic Intellectual Property Management Co., Ltd. | Screen |
| EP3436610A1 (en) * | 2016-03-29 | 2019-02-06 | Geltor, Inc. | Expression of proteins in gram-negative bacteria wherein the ratio of periplasmic volume to cytoplasmic volume is between 0.5:1 and 10:1 |
| BR112018072043A2 (pt) | 2016-05-06 | 2019-02-12 | Glaxosmithkline Intellectual Property Development Limited | sequências de sinal e de ácido nucleico recombinantes, proteína de fusão recombinante, vetor de expressão recombinante, e, métodos para produzir uma proteína recombinante e controlar a viscosidade de um caldo de célula hospedeira e a expressão de uma proteína recombinante |
| GB201704659D0 (en) * | 2017-03-24 | 2017-05-10 | Fujifilm Diosynth Biotechnologies Uk Ltd | Expression system |
| US20230151071A1 (en) * | 2020-04-09 | 2023-05-18 | United States Government As Represented By The Department Of Veterans Affairs | Compositions comprising recombinant epo and methods of use thereof |
| US20230167467A1 (en) * | 2020-04-15 | 2023-06-01 | University of Alaska Anchorage | Methods and compositions for the production of isobutene |
| CN118488963A (zh) | 2021-12-17 | 2024-08-13 | 肯特大学 | 囊泡中生产重组生物分子的序列和方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8517071D0 (en) * | 1985-07-05 | 1985-08-14 | Hoffmann La Roche | Gram-positive expression control sequence |
| US5059530A (en) * | 1985-09-30 | 1991-10-22 | Suntory Ltd. | Expression vector for human TNF |
| JPS63267288A (ja) | 1986-12-26 | 1988-11-04 | Hoechst Japan Kk | 増幅された遺伝子によつて蛋白質を生産する方法およびそのための遺伝子 |
| US5510099A (en) * | 1987-05-01 | 1996-04-23 | Stratagene | Mutagenesis testing using transgenic non-human animals carrying test DNA sequences |
| US5223407A (en) * | 1988-08-31 | 1993-06-29 | Allelix Inc. | Excretion of heterologous proteins from e. coli |
| WO1991013979A1 (en) | 1990-03-05 | 1991-09-19 | President And Fellows Of Harvard College | Transgenic mouse overexpressing il-4 and method of use |
| DE4029844A1 (de) * | 1990-09-20 | 1992-03-26 | Boehringer Mannheim Gmbh | Carbamoylsarcosinhydrolase, kloniert |
| US5589392A (en) | 1991-01-14 | 1996-12-31 | Stratagene | Nucleic acid construct encoding a nuclear transport peptide operatively linked to an inducible promoter |
| GB2253210B (en) * | 1991-02-26 | 1995-06-07 | Ici Plc | Soluble heterologous polypeptide produced by culture of recombinant microorganisms |
| GB2253852B (en) | 1991-02-26 | 1995-03-22 | Ici Plc | Vector for expression of heterologous polypeptide comprising inducible selection system |
| CA2130081A1 (en) | 1992-02-14 | 1993-08-19 | Jay M. Short | Mutagenesis testing using transgenic non-human animals carrying test dna sequences |
| WO1998022578A1 (fr) | 1996-11-15 | 1998-05-28 | Institute Of Cytosignal Research, Inc. | Procedes servant a detecter et a isoler des genes |
| WO1998022581A1 (fr) | 1996-11-15 | 1998-05-28 | Institute Of Cytosignal Research, Inc. | Represseur de transcription |
| WO1999005279A1 (en) | 1997-07-25 | 1999-02-04 | Zeneca Limited | Mcp-1 analogs |
| GB9715660D0 (en) * | 1997-07-25 | 1997-10-01 | Zeneca Ltd | Proteins |
| EP1183357A2 (en) * | 1999-05-20 | 2002-03-06 | Scios Inc. | Vascular endothelial growth factor dimers |
| EP1373297A4 (en) | 2001-03-05 | 2005-09-21 | Univ Virginia | A LAC OPERATOR REPRESSOR SYSTEM |
| GB0113318D0 (en) | 2001-06-01 | 2001-07-25 | Lonza Biologics Plc | Method for production of a protein |
| GB0227346D0 (en) * | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| AU2003299732A1 (en) | 2002-12-18 | 2004-07-14 | Genpath Pharmaceuticals, Incorporated | Vectors for inducible rna interference |
| WO2005052151A1 (en) | 2003-11-19 | 2005-06-09 | Dow Global Technologies Inc. | Improved protein expression systems |
| US20060177895A1 (en) * | 2003-12-12 | 2006-08-10 | Chung Chan | Methods for enhancing expression of recombinant proteins |
| WO2005071089A2 (en) | 2004-01-12 | 2005-08-04 | Vertex Pharmaceuticals Incorporated | Dual host expression vector system and screening methods |
| JP4854202B2 (ja) * | 2004-03-31 | 2012-01-18 | 株式会社日本触媒 | 新規改変型ｓ−ヒドロキシニトリルリアーゼ |
| JP2005314252A (ja) * | 2004-04-27 | 2005-11-10 | Okayama Univ | 糖尿病性腎症の予防・治療剤 |
| JP2005341803A (ja) * | 2004-05-31 | 2005-12-15 | Institute Of Physical & Chemical Research | 非対称な塩基配列を認識して切断する酵素Ｉ−ＣｓｍＩ及びその製造方法 |
| GB0602173D0 (en) * | 2006-02-03 | 2006-03-15 | Avecia Ltd | Expression system |
| RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
| US9388425B2 (en) | 2006-10-20 | 2016-07-12 | Trustees Of Boston University | Tunable genetic switch for regulating gene expression |
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2006
- 2006-02-03 GB GBGB0602173.7A patent/GB0602173D0/en not_active Ceased
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2007
- 2007-02-01 EP EP07712658.9A patent/EP1984506B1/en active Active
- 2007-02-01 PT PT77126589T patent/PT1984506E/pt unknown
- 2007-02-01 DK DK13191424.4T patent/DK2695943T3/en active
- 2007-02-01 PL PL13191424T patent/PL2695943T3/pl unknown
- 2007-02-01 CN CN201210056815.2A patent/CN102690834B/zh active Active
- 2007-02-01 EP EP11172434.0A patent/EP2390334B1/en not_active Not-in-force
- 2007-02-01 SG SG201100858-8A patent/SG169390A1/en unknown
- 2007-02-01 ES ES13191424.4T patent/ES2569075T3/es active Active
- 2007-02-01 DK DK07712658.9T patent/DK1984506T3/da active
- 2007-02-01 HU HUE13191424A patent/HUE027350T2/hu unknown
- 2007-02-01 ES ES11171994.4T patent/ES2445173T3/es active Active
- 2007-02-01 PL PL07712658T patent/PL1984506T3/pl unknown
- 2007-02-01 PL PL11171994T patent/PL2386642T3/pl unknown
- 2007-02-01 US US12/223,527 patent/US8530188B2/en active Active
- 2007-02-01 ES ES07712658.9T patent/ES2436883T3/es active Active
- 2007-02-01 SG SG201100857-0A patent/SG169389A1/en unknown
- 2007-02-01 CN CN2007800112768A patent/CN101410523B/zh active Active
- 2007-02-01 JP JP2008552885A patent/JP5221385B2/ja active Active
- 2007-02-01 CA CA2959915A patent/CA2959915C/en active Active
- 2007-02-01 KR KR1020147026047A patent/KR101624345B1/ko active Active
- 2007-02-01 EP EP13191424.4A patent/EP2695943B1/en active Active
- 2007-02-01 DK DK11172432.4T patent/DK2386644T3/en active
- 2007-02-01 EP EP11172432.4A patent/EP2386644B1/en active Active
- 2007-02-01 WO PCT/GB2007/000351 patent/WO2007088371A2/en not_active Ceased
- 2007-02-01 CA CA2637818A patent/CA2637818C/en active Active
- 2007-02-01 KR KR1020087018552A patent/KR101492844B1/ko active Active
- 2007-02-01 KR KR1020147017744A patent/KR101512776B1/ko active Active
- 2007-02-01 CN CN201810774783.7A patent/CN108841848B/zh active Active
- 2007-02-01 EP EP11172429.0A patent/EP2386643B1/en active Active
- 2007-02-01 PT PT111719944T patent/PT2386642E/pt unknown
- 2007-02-01 EP EP11171994.4A patent/EP2386642B1/en active Active
- 2007-02-01 SG SG201100856-2A patent/SG169388A1/en unknown
- 2007-02-01 DK DK11171994.4T patent/DK2386642T3/en active
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2008
- 2008-07-17 ZA ZA200806238A patent/ZA200806238B/xx unknown
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2010
- 2010-07-12 ZA ZA2010/04904A patent/ZA201004904B/en unknown
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2012
- 2012-11-21 JP JP2012255098A patent/JP5713984B2/ja active Active
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2013
- 2013-08-14 US US13/966,600 patent/US9677103B2/en active Active
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2014
- 2014-08-21 JP JP2014168362A patent/JP2015006193A/ja active Pending
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2016
- 2016-02-23 JP JP2016031742A patent/JP6298481B2/ja active Active
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2017
- 2017-03-06 JP JP2017041457A patent/JP6571707B2/ja active Active
- 2017-05-08 US US15/588,851 patent/US11098335B2/en active Active
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2021
- 2021-07-16 US US17/377,805 patent/US20210348205A1/en not_active Abandoned
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