HUE027076T2 - Combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases - Google Patents

Combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases Download PDF

Info

Publication number
HUE027076T2
HUE027076T2 HUE06723360A HUE06723360A HUE027076T2 HU E027076 T2 HUE027076 T2 HU E027076T2 HU E06723360 A HUE06723360 A HU E06723360A HU E06723360 A HUE06723360 A HU E06723360A HU E027076 T2 HUE027076 T2 HU E027076T2
Authority
HU
Hungary
Prior art keywords
medicament
copd
treatment
glycopyrrolate
combination
Prior art date
Application number
HUE06723360A
Other languages
English (en)
Hungarian (hu)
Inventor
Joachim Maus
Beatrix Fyrnys
Torsten Hoffmann
Mario Weingart
Istvan Szelenyi
Peter Juergen Cnota
Ullrich Munzel
Ursula Petzold
Original Assignee
Meda Pharma Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meda Pharma Gmbh & Co Kg filed Critical Meda Pharma Gmbh & Co Kg
Publication of HUE027076T2 publication Critical patent/HUE027076T2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HUE06723360A 2005-03-16 2006-03-10 Combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases HUE027076T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66191805P 2005-03-16 2005-03-16

Publications (1)

Publication Number Publication Date
HUE027076T2 true HUE027076T2 (en) 2016-08-29

Family

ID=36570797

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE06723360A HUE027076T2 (en) 2005-03-16 2006-03-10 Combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases

Country Status (18)

Country Link
US (1) US8268864B2 (enExample)
EP (1) EP1863476B1 (enExample)
JP (1) JP4991693B2 (enExample)
CN (1) CN101128196B (enExample)
AU (1) AU2006224842B2 (enExample)
CA (1) CA2595791C (enExample)
CY (1) CY1117571T1 (enExample)
DK (1) DK1863476T3 (enExample)
ES (1) ES2570332T3 (enExample)
HR (1) HRP20160373T1 (enExample)
HU (1) HUE027076T2 (enExample)
MX (1) MX2007011273A (enExample)
NO (1) NO340405B1 (enExample)
NZ (1) NZ560206A (enExample)
PL (1) PL1863476T3 (enExample)
RU (1) RU2420285C2 (enExample)
SI (1) SI1863476T1 (enExample)
WO (1) WO2006097250A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050048614A1 (en) * 2000-06-13 2005-03-03 Children's Medical Center Corporation Biosynthetic oncolytic molecules and uses therefor
DE602004016002D1 (de) * 2003-07-28 2008-10-02 Janssen Pharmaceutica Nv Benzimidazol-, benzothiazol- und benzoxazolderivate und deren verwendung als lta4h-modulatoren
ES2614090T3 (es) 2005-12-29 2017-05-29 Celtaxsys, Inc. Derivados de diamina como inhibidores de leucotrieno A4 hidrolasa
TW200906396A (en) * 2007-02-14 2009-02-16 Janssen Pharmaceutica Nv LTA4H modulators and uses thereof
EP2200550B1 (en) 2007-10-18 2018-04-18 Rose U, LLC Topical glycopyrrolate formulations
AU2008316283A1 (en) * 2007-10-25 2009-04-30 Merck Frosst Canada Ltd Inhalation compositions comprising montelukast acid and a PDE-4 inhibitor or an inhaled corticosteroid
CA2764867C (en) * 2009-06-09 2016-05-17 Elevation Pharmaceuticals, Inc. Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration
US9378456B2 (en) * 2012-11-19 2016-06-28 Microsoft Technology Licensing, Llc Task completion
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
EP2961734B1 (en) 2013-02-28 2018-09-26 Dermira, Inc. Glycopyrrolate salts
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
WO2014164658A1 (en) * 2013-03-12 2014-10-09 Celtaxsys, Inc. Methods of inhibiting leukotriene a4 hydrolase
KR20150127245A (ko) 2013-03-14 2015-11-16 켈탁시스, 인코퍼레이티드 류코트라이엔 a4 가수분해효소의 저해제
SG10202000496XA (en) * 2014-01-10 2020-03-30 Afimmune Ltd Pharmaceutical compositions comprising 15-hepe and methods of treating asthma and lung disorders using same
CA3102077A1 (en) 2018-05-31 2019-12-05 Sanjeev AHUJA Method of reducing pulmonary exacerbations in respiratory disease patients
TW202042813A (zh) * 2019-01-10 2020-12-01 大陸商江陰貝瑞森製藥有限公司 含有白三烯受體拮抗劑的新穎調配物
AU2021215849B2 (en) * 2020-02-03 2023-08-03 Taro Pharmaceutical Industries Ltd. Topical montelukast formulations
CN115792229B (zh) * 2022-01-28 2024-06-18 华中科技大学同济医学院附属同济医院 鼻分泌物中tPA在制备鼻息肉及其预后检测剂中的应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0435038A (ja) * 1990-05-31 1992-02-05 Oki Electric Ind Co Ltd 半導体素子及びその製造方法
CZ290266B6 (cs) * 1993-07-02 2002-06-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituované benzamidy, způsob jejich výroby a farmaceutické prostředky s jejich obsahem
EP0932401A1 (en) 1996-07-01 1999-08-04 Sepracor, Inc. Methods and compositions for treating urinary incontinence using enantiomerically enriched (r,r)-glycopyrrolate
DK0937041T3 (da) * 1996-11-11 2003-08-11 Christian R Noe Anvendelse af et farmaceutisk egnet salt af (3R,2'R)-3-[(cyclopentil-hydroxyphenylacetyl)oxyl]-1,1-dimethyl-pyrrolidinium til fremstilling af et lægemiddel
EP0979105A1 (en) * 1997-04-30 2000-02-16 Warner-Lambert Company Topical nasal antiinflammatory compositions
US6384038B1 (en) * 1998-04-14 2002-05-07 Sepracor Inc. Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants
AU7455498A (en) * 1998-05-29 1999-12-20 Citizen Watch Co. Ltd. Method of subjecting ink jet printer to preuse treatment
DK1102579T3 (da) * 1998-08-04 2003-07-14 Jago Res Ag Medicinske aerosolformuleringer
NZ511527A (en) * 1998-11-13 2002-10-25 Jago Res A Dry powder for inhalation
DE19921693A1 (de) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
US6086914A (en) * 1999-03-12 2000-07-11 Weinstein; Robert E. Nonsedating formulations for allergic rhinitis which possess antihistaminic and anticholinergic activity
US20040002548A1 (en) * 1999-05-12 2004-01-01 Boehringer Ingelheim Pharma Kg Medicament compositions containing anticholinergically-effective compounds and betamimetics
SE9903995D0 (sv) * 1999-11-03 1999-11-03 Astra Ab New combination
DE19961300A1 (de) * 1999-12-18 2001-06-21 Asta Medica Ag Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
GB0008660D0 (en) 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
GB0009583D0 (en) 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
AU2002221741B2 (en) * 2000-10-31 2007-04-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative solution formulation containing a tiotropium salt
DE10110772A1 (de) 2001-03-07 2002-09-12 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und PDE-IV-Inhibitoren
GB0029903D0 (en) * 2000-12-07 2001-01-24 Arakis Ltd Use of anti-muscarinic agents
DE50211045D1 (de) 2001-03-30 2007-11-22 Jagotec Ag Medizinische aerosolformulierungen
US6667344B2 (en) * 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
JP2004530705A (ja) 2001-05-25 2004-10-07 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 閉塞性気道疾患及びその他の炎症性疾患を治療するためのpde4インヒビター及びチオトロピウム又はその誘導体の組み合わせ
OA12610A (en) 2001-05-25 2006-06-09 Pfizer A PDE 4 inhbitor and an anti-cholinergic agent in combination for treating obstructive airways diseases.
GB0118373D0 (en) 2001-07-27 2001-09-19 Glaxo Group Ltd Novel therapeutic method
MY148466A (en) * 2001-10-26 2013-04-30 Merck Frosst Canada Ltd Granule formulation
US7258118B2 (en) * 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
ES2275778T3 (es) * 2002-06-06 2007-06-16 Chiesi Farmaceutici S.P.A. Solubilizacion de farmacos en propulsores de hfa mediante emulsiones.
US20040038958A1 (en) * 2002-07-11 2004-02-26 Chris Rundfeldt Topical treatment of skin diseases
UA82323C2 (uk) 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
AU2003272450A1 (en) * 2002-09-13 2004-04-30 C. Steven Smith Novel composition and method for treatment of upper respiratory conditions
WO2004054556A1 (en) * 2002-12-13 2004-07-01 Adagit Pharmaceutical porous particles
EP1452179A1 (en) * 2003-02-27 2004-09-01 CHIESI FARMACEUTICI S.p.A. Novel medicament combination of a highly potent long-lasting beta2-agonist and a corticosteroid
PT1610787E (pt) * 2003-03-28 2008-04-23 Nycomed Gmbh Associação sinérgica compreendendo roflumilast e um agente anticolinérgico seleccionado de sais de tiotrópio para o tratamento de doenças respiratórias
WO2005055999A1 (ja) 2003-12-08 2005-06-23 Nippon Shinyaku Co., Ltd. 抗コリン作用剤
GB0411056D0 (en) * 2004-05-18 2004-06-23 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
CY1117571T1 (el) 2017-04-26
MX2007011273A (es) 2007-11-08
JP4991693B2 (ja) 2012-08-01
CN101128196A (zh) 2008-02-20
US8268864B2 (en) 2012-09-18
ES2570332T3 (es) 2016-05-17
CA2595791A1 (en) 2006-09-21
WO2006097250A1 (en) 2006-09-21
EP1863476B1 (en) 2016-02-03
CA2595791C (en) 2013-10-08
DK1863476T3 (en) 2016-05-17
US20060211729A1 (en) 2006-09-21
SI1863476T1 (sl) 2016-05-31
RU2007138270A (ru) 2009-04-27
HRP20160373T1 (hr) 2016-05-06
NO340405B1 (no) 2017-04-18
AU2006224842A1 (en) 2006-09-21
NO20075287L (no) 2007-12-05
RU2420285C2 (ru) 2011-06-10
JP2008533072A (ja) 2008-08-21
HK1114013A1 (en) 2008-10-24
CN101128196B (zh) 2013-01-02
EP1863476A1 (en) 2007-12-12
AU2006224842B2 (en) 2011-09-29
PL1863476T3 (pl) 2016-07-29
NZ560206A (en) 2009-09-25

Similar Documents

Publication Publication Date Title
EP1863476B1 (en) The combination of anticholinergics and leukotriene receptor antagonists for the treatment of respiratory diseases
TWI404530B (zh) 包含抗蕈毒鹼劑及β-腎上腺素激動劑之組合
US20080300226A1 (en) Combination of Anticholinergics and Glucocorticoids for the Long-Term Treatment of Asthma and COPD
CN100512813C (zh) 用于呼吸道疾病治疗的抗胆碱能药和4型磷酸二酯酶抑制剂的组合
EP1819329A2 (en) Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
RS50786B (sr) Kombinacije koje sadrže antimuskarinska sredstva i beta-adrenergične agoniste
UA119773C2 (uk) Комбінації тіотропію броміду, формотеролу і будесоніду для лікування хронічної обструктивної хвороби легень (хохл)
US11571412B2 (en) Thromboxane receptor antagonists in AERD/asthma
HK1114013B (en) The combination of anticholinergics and leukotriene receptor antagonists for the treatment of repiratory diseases
HK40066392A (zh) Aerd/哮喘中的血栓烷受体拮抗剂
KR20230116048A (ko) 펙소페나딘을 포함하는 조성물
KR20070018104A (ko) 항무스카린제 및 베타-아드레날린 작용제를 포함하는조합물