HU196368B - Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid - Google Patents

Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid Download PDF

Info

Publication number
HU196368B
HU196368B HU862811A HU281186A HU196368B HU 196368 B HU196368 B HU 196368B HU 862811 A HU862811 A HU 862811A HU 281186 A HU281186 A HU 281186A HU 196368 B HU196368 B HU 196368B
Authority
HU
Hungary
Prior art keywords
bromo
methyl
acid
benzyl ester
pyrrolidine
Prior art date
Application number
HU862811A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT44491A (en
Inventor
Janos Toempe
Laszlo Dobay
Janos Fischer
Mihaly Majos
Endrene Petenyi
Laszlone Koncz
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU862811A priority Critical patent/HU196368B/hu
Priority to YU01180/87A priority patent/YU118087A/xx
Priority to CH2523/87A priority patent/CH672786A5/de
Priority to NO872796A priority patent/NO872796L/no
Priority to ES8701951A priority patent/ES2004443A6/es
Priority to SE8702753A priority patent/SE8702753L/xx
Priority to DD87304596A priority patent/DD263984A5/de
Priority to DK343587A priority patent/DK343587A/da
Priority to GR871051A priority patent/GR871051B/el
Priority to CS875051A priority patent/CS262693B2/cs
Priority to CN198787104582A priority patent/CN87104582A/zh
Priority to JP62166755A priority patent/JPS6322557A/ja
Priority to PL1987266620A priority patent/PL150350B1/pl
Priority to AT0168087A priority patent/AT387382B/de
Priority to FI872966A priority patent/FI872966A/fi
Priority to PT85256A priority patent/PT85256B/pt
Priority to IT21179/87A priority patent/IT1221952B/it
Priority to KR1019870007155A priority patent/KR880001589A/ko
Priority to DE19873722278 priority patent/DE3722278A1/de
Publication of HUT44491A publication Critical patent/HUT44491A/hu
Publication of HU196368B publication Critical patent/HU196368B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B9/00—General processes of refining or remelting of metals; Apparatus for electroslag or arc remelting of metals
    • C22B9/02—Refining by liquating, filtering, centrifuging, distilling, or supersonic wave action including acoustic waves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Acoustics & Sound (AREA)
  • Manufacturing & Machinery (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU862811A 1986-07-04 1986-07-04 Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid HU196368B (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
HU862811A HU196368B (en) 1986-07-04 1986-07-04 Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid
YU01180/87A YU118087A (en) 1986-07-04 1987-06-24 Process for obtaining acylated heterocyclic substance
CH2523/87A CH672786A5 (ko) 1986-07-04 1987-07-02
NO872796A NO872796L (no) 1986-07-04 1987-07-03 FremgangsmŸte for fremstilling av en acylert heterocyklisk forbindelse.
ES8701951A ES2004443A6 (es) 1986-07-04 1987-07-03 Procedimiento de preparacion del acido 1-(3-bromo-(2s)-metilpropionil)-pirrolidin-(2s)-carboxilico
SE8702753A SE8702753L (sv) 1986-07-04 1987-07-03 Forfarande for framstellning av en acylerad heterocyklisk forening
DD87304596A DD263984A5 (de) 1986-07-04 1987-07-03 Verfahren zur herstellung von 1-[3-brom-(2s)-methylpropionyl]-pyrrolidin-(2s)-carbonsaeure
DK343587A DK343587A (da) 1986-07-04 1987-07-03 Acylerede heterocycliske forbindelser
GR871051A GR871051B (en) 1986-07-04 1987-07-03 A process for preparing an acylated heterocyclic compound
CS875051A CS262693B2 (en) 1986-07-04 1987-07-03 Process for preparing 1-/3-brom-/2s/-methylpropionyl/pyrrolidin-/2s/-carboxylic acid
CN198787104582A CN87104582A (zh) 1986-07-04 1987-07-03 制备酰化的杂环化合物的方法
JP62166755A JPS6322557A (ja) 1986-07-04 1987-07-03 アシル化複素環化合物の製造方法
PL1987266620A PL150350B1 (en) 1986-07-04 1987-07-03 Method of obtaining 1-3-bromo-/2s/-methylpropionyl -pyrrolidine-/2s/-carboxylic acid of formula 1 and its monohydride
AT0168087A AT387382B (de) 1986-07-04 1987-07-03 Verfahren zur herstellung eines bromacylprolins
FI872966A FI872966A (fi) 1986-07-04 1987-07-03 Foerfarande foer framstaellning av en acylerad heterocyklisk foerening.
PT85256A PT85256B (pt) 1986-07-04 1987-07-03 Processo para a preparacao de acido 1-(3-bromo-{2s}-metilpropionil)-pirrolidino-{2s}-carboxilico
IT21179/87A IT1221952B (it) 1986-07-04 1987-07-03 Procedimento per preparare un composto eterociclico acilato
KR1019870007155A KR880001589A (ko) 1986-07-04 1987-07-04 아실화된 헤테르고리 화합물의 제조방법
DE19873722278 DE3722278A1 (de) 1986-07-04 1987-07-06 Verfahren zur herstellung von 1-(3'-(brom)-(2's)-(methyl)-propionyl) -pyrrolidin-(2s)-carbonsaeure oder ihres monohydrates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU862811A HU196368B (en) 1986-07-04 1986-07-04 Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid

Publications (2)

Publication Number Publication Date
HUT44491A HUT44491A (en) 1988-03-28
HU196368B true HU196368B (en) 1988-11-28

Family

ID=10961203

Family Applications (1)

Application Number Title Priority Date Filing Date
HU862811A HU196368B (en) 1986-07-04 1986-07-04 Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid

Country Status (19)

Country Link
JP (1) JPS6322557A (ko)
KR (1) KR880001589A (ko)
CN (1) CN87104582A (ko)
AT (1) AT387382B (ko)
CH (1) CH672786A5 (ko)
CS (1) CS262693B2 (ko)
DD (1) DD263984A5 (ko)
DE (1) DE3722278A1 (ko)
DK (1) DK343587A (ko)
ES (1) ES2004443A6 (ko)
FI (1) FI872966A (ko)
GR (1) GR871051B (ko)
HU (1) HU196368B (ko)
IT (1) IT1221952B (ko)
NO (1) NO872796L (ko)
PL (1) PL150350B1 (ko)
PT (1) PT85256B (ko)
SE (1) SE8702753L (ko)
YU (1) YU118087A (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8802849A (nl) * 1988-11-18 1990-06-18 Stamicarbon Werkwijze voor de enantioselectieve bereiding van d-(-)-3-hal-methylpropionzuur of derivaten daarvan en de bereiding van captopril daaruit.
CN103086939A (zh) * 2011-10-28 2013-05-08 华中药业股份有限公司 1-(3-溴-2-d-甲基丙酰基)吡咯烷-2-羧酸的重结晶方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
IE50839B1 (en) * 1980-02-26 1986-07-23 Wyeth John & Brother Ltd Novel processes for preparing proline derivatives and analogous compounds

Also Published As

Publication number Publication date
DK343587D0 (da) 1987-07-03
DE3722278A1 (de) 1988-01-07
DD263984A5 (de) 1989-01-18
AT387382B (de) 1989-01-10
CS262693B2 (en) 1989-03-14
NO872796L (no) 1988-01-05
PL266620A1 (en) 1988-07-07
JPS6322557A (ja) 1988-01-30
KR880001589A (ko) 1988-04-25
HUT44491A (en) 1988-03-28
SE8702753D0 (sv) 1987-07-03
ATA168087A (de) 1988-06-15
CH672786A5 (ko) 1989-12-29
ES2004443A6 (es) 1989-01-01
FI872966A (fi) 1988-01-05
GR871051B (en) 1987-11-09
IT1221952B (it) 1990-08-31
FI872966A0 (fi) 1987-07-03
IT8721179A0 (it) 1987-07-03
YU118087A (en) 1988-06-30
PT85256B (pt) 1990-03-30
CS505187A2 (en) 1988-08-16
PL150350B1 (en) 1990-05-31
CN87104582A (zh) 1988-01-20
DK343587A (da) 1988-01-05
PT85256A (en) 1987-08-01
SE8702753L (sv) 1988-01-05
NO872796D0 (no) 1987-07-03

Similar Documents

Publication Publication Date Title
US4562263A (en) Process for producing 3-(3,4-dihydroxyphenyl) serine
JP2691442B2 (ja) 新規なプロリン誘導体
NO313095B1 (no) Fremgangsmåte ved fremstilling av perhydroisoindol
HU201523B (en) Process for producing retinoyl chlorides
KR100498869B1 (ko) Ｎ-[(ｓ）-１-카르복시부틸]-（ｓ）-알라닌 에스테르 및페린도프릴의 합성에서의 용도
US6197998B1 (en) Process for producing N-glycyltyrosine and its crystal structure
KR100722079B1 (ko) Ｓ-인돌린-2-카르복실산의 합성 방법 및 페린도프릴 합성시이의 적용 방법
KR100447072B1 (ko) 에난티오머적으로순수한아제티딘-2-카르복실산의개선된제조방법
HU196368B (en) Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid
EP0481118A1 (en) A method for producing butyl 3'-(1H-tetrazol-5-yl) oxanilate
US4508657A (en) Peptide synthesis and amino acid blocking agents
JPH11349567A (ja) ３―アミノ―２―オキソ―ピロリジンの製造方法、新規中間体およびその使用
US4581167A (en) Peptide synthesis and amino acid blocking agents
CA2236117C (en) Process for producing optically active cyanohydrins
CA1273932A (en) Process for production of dihydropyridine compound or salts thereof
JP3663643B2 (ja) 光学活性１−（２，４−ジクロロフェニル）エチルアミンの製造法
EP0219651B1 (en) Inorganic acid salt of N-[1(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanylchloride and process for preparing the same
JPH069553A (ja) １−［｜２ｓ｜−メチル−３−メルカプトプロピオニル−ピロリジン−｜２ｓ｜−カルボン酸の製法
JP2000178253A (ja) 光学活性ピペコリン酸の製造法
HU214581B (hu) N2-(1S)-(1-/Etoxi-karbonil/-3-fenil-propil)-N6-(trifluor-acetil)-(L)-lizil-(L)-prolin-benzil-észter és eljárás előállítására
HU208954B (en) Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
KR100262285B1 (ko) 1.1'-비-2-나프톨의 순수한 광학 이성체의 제조방법
KR100486320B1 (ko) 5,11-디히드로-6에이치-디벤즈[비,이]아제핀-6-온의제조방법
JP2005263748A (ja) 反応性ジアジリン基を有するホモフェニルアラニン誘導体
JPH09241227A (ja) 新規光学分割剤

Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HC9A Change of name, address

Owner name: EGIS GYOGYSZERGYAR NYRT., HU

Free format text: FORMER OWNER(S): EGIS GYOGYSZERGYAR, HU