KR880001589A - 아실화된 헤테르고리 화합물의 제조방법 - Google Patents

아실화된 헤테르고리 화합물의 제조방법 Download PDF

Info

Publication number
KR880001589A
KR880001589A KR1019870007155A KR870007155A KR880001589A KR 880001589 A KR880001589 A KR 880001589A KR 1019870007155 A KR1019870007155 A KR 1019870007155A KR 870007155 A KR870007155 A KR 870007155A KR 880001589 A KR880001589 A KR 880001589A
Authority
KR
South Korea
Prior art keywords
heterocyclic compound
general formula
formula
preparing acylated
carbodiimide
Prior art date
Application number
KR1019870007155A
Other languages
English (en)
Inventor
툄페 야노스
피셔 야노스
도베이 라즈로
콘쯔 라즈로
메조르 미할리
페테니 에바
Original Assignee
이스트반 시모니, 아틸라 만디
에기스 교지스제르기아르
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이스트반 시모니, 아틸라 만디, 에기스 교지스제르기아르 filed Critical 이스트반 시모니, 아틸라 만디
Publication of KR880001589A publication Critical patent/KR880001589A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B9/00—General processes of refining or remelting of metals; Apparatus for electroslag or arc remelting of metals
    • C22B9/02—Refining by liquating, filtering, centrifuging, distilling, or supersonic wave action including acoustic waves

Abstract

내용 없음

Description

아실화된 헤테르고리 화합물의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 하기 일반식(Ⅲ)의 염을 불활성 유기용매에서 축합제와 반응시켜 수득한 하기 일반식(Ⅱ)의 벤질1-[3-브로모-(2S)-메닐프포피오닐]-피롤리딘-(2S)-카르복실레이트를 접촉 수소화 반응으로 탈벤질화시켜 하기 일반식(I)의 생성물로 제조하고, 하기 일반식(I)의 생성물을 물에서 재결정하여 그의 1수화물을 제조함을 특징으로 하는 하기 일반식(I)의 1-[3-브로모-(2S)-메틸프로피오닐]-피롤리딘-(2S)-카르복실산 및 그의 1수화물의 제조방법.
  2. 제 1항에 있어서, 축합제가 카아보디이미드임을 특징으로 하는 제조방법.
  3. 제 2항에 있어서, 카아보디이미드가 N,N'-디시클로헥실카아보디이미드임을 특징으로 하는 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870007155A 1986-07-04 1987-07-04 아실화된 헤테르고리 화합물의 제조방법 KR880001589A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU862811A HU196368B (en) 1986-07-04 1986-07-04 Process for production of 1-/3-brom-/25/-methil-prophionil/-pirrolidin-/25/-carbonic acid
HU2811/86 1986-07-04

Publications (1)

Publication Number Publication Date
KR880001589A true KR880001589A (ko) 1988-04-25

Family

ID=10961203

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870007155A KR880001589A (ko) 1986-07-04 1987-07-04 아실화된 헤테르고리 화합물의 제조방법

Country Status (19)

Country Link
JP (1) JPS6322557A (ko)
KR (1) KR880001589A (ko)
CN (1) CN87104582A (ko)
AT (1) AT387382B (ko)
CH (1) CH672786A5 (ko)
CS (1) CS262693B2 (ko)
DD (1) DD263984A5 (ko)
DE (1) DE3722278A1 (ko)
DK (1) DK343587A (ko)
ES (1) ES2004443A6 (ko)
FI (1) FI872966A (ko)
GR (1) GR871051B (ko)
HU (1) HU196368B (ko)
IT (1) IT1221952B (ko)
NO (1) NO872796L (ko)
PL (1) PL150350B1 (ko)
PT (1) PT85256B (ko)
SE (1) SE8702753L (ko)
YU (1) YU118087A (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8802849A (nl) * 1988-11-18 1990-06-18 Stamicarbon Werkwijze voor de enantioselectieve bereiding van d-(-)-3-hal-methylpropionzuur of derivaten daarvan en de bereiding van captopril daaruit.
CN103086939A (zh) * 2011-10-28 2013-05-08 华中药业股份有限公司 1-(3-溴-2-d-甲基丙酰基)吡咯烷-2-羧酸的重结晶方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
IE50839B1 (en) * 1980-02-26 1986-07-23 Wyeth John & Brother Ltd Novel processes for preparing proline derivatives and analogous compounds

Also Published As

Publication number Publication date
CH672786A5 (ko) 1989-12-29
PL266620A1 (en) 1988-07-07
CS505187A2 (en) 1988-08-16
FI872966A0 (fi) 1987-07-03
PT85256B (pt) 1990-03-30
YU118087A (en) 1988-06-30
GR871051B (en) 1987-11-09
PT85256A (en) 1987-08-01
AT387382B (de) 1989-01-10
NO872796L (no) 1988-01-05
CN87104582A (zh) 1988-01-20
IT1221952B (it) 1990-08-31
DK343587A (da) 1988-01-05
ATA168087A (de) 1988-06-15
JPS6322557A (ja) 1988-01-30
FI872966A (fi) 1988-01-05
DK343587D0 (da) 1987-07-03
SE8702753D0 (sv) 1987-07-03
PL150350B1 (en) 1990-05-31
NO872796D0 (no) 1987-07-03
DE3722278A1 (de) 1988-01-07
DD263984A5 (de) 1989-01-18
HUT44491A (en) 1988-03-28
HU196368B (en) 1988-11-28
IT8721179A0 (it) 1987-07-03
CS262693B2 (en) 1989-03-14
SE8702753L (sv) 1988-01-05
ES2004443A6 (es) 1989-01-01

Similar Documents

Publication Publication Date Title
KR850006939A (ko) 아실트리펩타이드의 제조방법
KR870003998A (ko) 퀴나졸린 유도체류의 제조방법
KR920008018A (ko) 피페라진 유도체의 제조방법
KR850004754A (ko) 3-인돌 카르복사미드 화합물류의 제조방법
KR850007601A (ko) 페남 유도체의 제조방법
KR910011771A (ko) 아미노부탄올 유도체 및 그로부터 3-피롤리디놀의 제조방법
KR880001589A (ko) 아실화된 헤테르고리 화합물의 제조방법
KR910002865A (ko) 피라노벤즈옥사디아졸 화합물 및 그 광학적 분할방법
KR850007257A (ko) 테트라 하이드로 퀴놀린-1-알카보닐 이미다졸 유도체의 제조방법
KR860001102A (ko) 디히드로오로트산 유도체의 제조방법
Basha et al. N-Methylation of Amides and Related Compounds by Reduction of Methylols
IT1197800B (it) Processo per la sintesi di acidi carbossilici
DE3750117D1 (de) Verfahren zur Herstellung von Indolinon-2-Derivaten.
ATE62235T1 (de) Verfahren zur herstellung von 6-amino-3-hydrazino-pyridazinderivaten.
KR870004974A (ko) 퀴놀론 카복실산 유도체의 제조방법
KR890005050A (ko) 테트라히드로프탈이미드 화합물 제조
KR920019742A (ko) L-프롤린 유도체의 제조방법
KR910006223A (ko) 2-알킬아미노-4-아미노벤젤술폰산의 제조방법
KR860001066A (ko) 피롤리딘 유도체의 제조방법
KR840005089A (ko) N-치환된 이미노-에스테르의 제조방법
KR850002462A (ko) 아미디노 우레아 유도체의 제조방법
ES514117A0 (es) "procedimiento para la preparacion de l-prolina".
KR910011892A (ko) 디펩타이드유도체의 제조방법
KR860003254A (ko) 옥타히드로인돌로〔 2,3-a〕퀴놀리진-1-일-알칸 카르복실산 아미드 및 그의 산부가염의 제조방법
KR880000384A (ko) 안식향산 유도체의 제조방법

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid