HU195668B - Process for producing 9-deoxo-4-comma above comma above-deoxy-4-comma above comma above-amino-9a-aza-9a-homoerythromycin derivatives - Google Patents
Process for producing 9-deoxo-4-comma above comma above-deoxy-4-comma above comma above-amino-9a-aza-9a-homoerythromycin derivatives Download PDFInfo
- Publication number
- HU195668B HU195668B HU851370A HU137085A HU195668B HU 195668 B HU195668 B HU 195668B HU 851370 A HU851370 A HU 851370A HU 137085 A HU137085 A HU 137085A HU 195668 B HU195668 B HU 195668B
- Authority
- HU
- Hungary
- Prior art keywords
- hydrogen
- formula
- amino
- compound
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/600,252 US4512982A (en) | 1984-04-13 | 1984-04-13 | 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method |
| US06/616,529 US4518590A (en) | 1984-04-13 | 1984-06-04 | 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT37629A HUT37629A (en) | 1986-01-23 |
| HU195668B true HU195668B (en) | 1988-06-28 |
Family
ID=27083554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU851370A HU195668B (en) | 1984-04-13 | 1985-04-12 | Process for producing 9-deoxo-4-comma above comma above-deoxy-4-comma above comma above-amino-9a-aza-9a-homoerythromycin derivatives |
Country Status (19)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075289A (en) * | 1988-06-07 | 1991-12-24 | Abbott Laboratories | 9-r-azacyclic erythromycin antibiotics |
| US4904644A (en) * | 1988-08-03 | 1990-02-27 | Schering Corporation | Antimicrobial compound isolated from Actinomadura fulva subsp indica |
| CA2062932A1 (en) | 1991-03-15 | 1992-09-16 | Robert R. Wilkening | 9-deoxo-9(z)-hydroxyiminoerythromycin a and o-derivatives thereof |
| US5912331A (en) * | 1991-03-15 | 1999-06-15 | Merck & Co., Inc. | Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A |
| US5985844A (en) * | 1992-03-26 | 1999-11-16 | Merck & Co., Inc. | Homoerythromycin A derivatives modified at the 4"-and 8A-positions |
| JPH06509326A (ja) * | 1991-04-09 | 1994-10-20 | アボツト・ラボラトリーズ | 大環式ラクタムプロキネティック剤 |
| US5189159A (en) * | 1992-04-02 | 1993-02-23 | Merck & Co., Inc. | 8a-AZA-8a-homoerythromycin cyclic iminoethers |
| US5523399A (en) * | 1991-12-27 | 1996-06-04 | Taisho Pharmaceutical Co., Ltd. | 5-O-desosaminylerythronolide derivatives |
| US5215980A (en) * | 1992-01-17 | 1993-06-01 | Merck & Co., Inc. | 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof |
| US5210235A (en) * | 1992-08-26 | 1993-05-11 | Merck & Co., Inc. | Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics |
| US5332807A (en) * | 1993-04-14 | 1994-07-26 | Merck & Co., Inc. | Process of producing 8A- and 9A-azalide antibiotics |
| DE69403963T2 (de) * | 1993-05-19 | 1997-11-20 | Pfizer | Zwischenprodukt für azithromycin |
| US5441939A (en) * | 1994-03-04 | 1995-08-15 | Pfizer Inc. | 3"-desmethoxy derivatives of erythromycin and azithromycin |
| FR2739620B1 (fr) * | 1995-10-09 | 1997-12-19 | Roussel Uclaf | Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs |
| USRE38426E1 (en) * | 1995-10-09 | 2004-02-10 | Aventis Pharma S.A. | 5-O-deosaminyl 6-O-methyl erythronolide A derivatives, preparation method therefor and use thereof for preparing biologically active materials |
| CA2419873A1 (en) | 2000-08-23 | 2002-02-28 | Wockhardt Limited | Process for preparation of anhydrous azithromycin |
| IL158059A0 (en) | 2001-04-27 | 2004-03-28 | Pfizer Prod Inc | Process for preparing 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives |
| NZ535355A (en) | 2002-02-15 | 2007-09-28 | Merckle Gmbh | Antibiotic conjugates |
| HRP20040849A2 (en) | 2002-02-15 | 2005-08-31 | Synovo Gmbh | Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof |
| NZ535354A (en) | 2002-02-15 | 2008-01-31 | Merckle Gmbh | Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof |
| GB0310992D0 (en) * | 2003-05-13 | 2003-06-18 | Glaxo Group Ltd | Novel compounds |
| US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
| US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4150220A (en) * | 1977-02-04 | 1979-04-17 | Pfizer Inc. | Semi-synthetic 4"-erythromycin A derivatives |
| SE445223B (sv) * | 1977-02-04 | 1986-06-09 | Pfizer | Sett att framstella 4"-amino-erytomylin-a-derivat |
| US4180654A (en) * | 1978-01-03 | 1979-12-25 | Pfizer Inc. | 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate |
| SI7910768A8 (en) * | 1979-04-02 | 1996-06-30 | Pliva Pharm & Chem Works | Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives |
| YU43006B (en) * | 1981-03-06 | 1989-02-28 | Pliva Pharm & Chem Works | Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof |
| US4474768A (en) * | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| US4465674A (en) * | 1983-09-06 | 1984-08-14 | Pfizer Inc. | Azahomoerythromycin D derivative and intermediates therefor |
-
1984
- 1984-06-04 US US06/616,529 patent/US4518590A/en not_active Expired - Lifetime
-
1985
- 1985-04-09 GR GR850900A patent/GR850900B/el not_active IP Right Cessation
- 1985-04-10 IL IL74865A patent/IL74865A/xx not_active IP Right Cessation
- 1985-04-10 DE DE8585302507T patent/DE3565267D1/de not_active Expired
- 1985-04-10 EP EP85302507A patent/EP0159856B1/en not_active Expired
- 1985-04-11 CA CA000478792A patent/CA1234805A/en not_active Expired
- 1985-04-11 IE IE912/85A patent/IE57739B1/en not_active IP Right Cessation
- 1985-04-11 PH PH32123A patent/PH21185A/en unknown
- 1985-04-11 ES ES542134A patent/ES8607335A1/es not_active Expired
- 1985-04-11 PT PT80270A patent/PT80270B/pt not_active IP Right Cessation
- 1985-04-11 EG EG239/85A patent/EG17459A/xx active
- 1985-04-11 FI FI851449A patent/FI851449L/fi not_active Application Discontinuation
- 1985-04-12 NO NO851466A patent/NO161497C/no not_active IP Right Cessation
- 1985-04-12 HU HU851370A patent/HU195668B/hu not_active IP Right Cessation
- 1985-04-12 DK DK164785A patent/DK164785A/da not_active IP Right Cessation
- 1985-04-12 NZ NZ211769A patent/NZ211769A/en unknown
- 1985-04-12 YU YU00623/85A patent/YU62385A/xx unknown
- 1985-04-12 AU AU41070/85A patent/AU549235B2/en not_active Ceased
- 1985-04-12 KR KR1019850002453A patent/KR860002111B1/ko not_active Expired
-
1986
- 1986-01-31 ES ES551502A patent/ES8705458A1/es not_active Expired
- 1986-01-31 ES ES551503A patent/ES8704965A1/es not_active Expired
-
1987
- 1987-07-06 YU YU01267/87A patent/YU126787A/xx unknown
- 1987-07-06 YU YU01268/87A patent/YU126887A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee | ||
| HRH9 | Withdrawal of annulment decision | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |