HU192461B - Process for preparing bbm-2478 antibiotic complex and components thereof, namely bbm-2478a and bbm-2478b antibiotics, further pharmaceutical compositions containing thereof - Google Patents

Process for preparing bbm-2478 antibiotic complex and components thereof, namely bbm-2478a and bbm-2478b antibiotics, further pharmaceutical compositions containing thereof Download PDF

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Publication number
HU192461B
HU192461B HU843724A HU372484A HU192461B HU 192461 B HU192461 B HU 192461B HU 843724 A HU843724 A HU 843724A HU 372484 A HU372484 A HU 372484A HU 192461 B HU192461 B HU 192461B
Authority
HU
Hungary
Prior art keywords
bbm
formula
antibiotic
strain
agar
Prior art date
Application number
HU843724A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT37170A (en
Inventor
Masataka Konishi
Koko Sugawara
Takeo Miyaki
Hiroshi Kawaguchi
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of HUT37170A publication Critical patent/HUT37170A/hu
Publication of HU192461B publication Critical patent/HU192461B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HU843724A 1983-10-03 1984-10-02 Process for preparing bbm-2478 antibiotic complex and components thereof, namely bbm-2478a and bbm-2478b antibiotics, further pharmaceutical compositions containing thereof HU192461B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/538,453 US4518589A (en) 1983-10-03 1983-10-03 BBM-2478 Antibiotic complex

Publications (2)

Publication Number Publication Date
HUT37170A HUT37170A (en) 1985-11-28
HU192461B true HU192461B (en) 1987-06-29

Family

ID=24146999

Family Applications (1)

Application Number Title Priority Date Filing Date
HU843724A HU192461B (en) 1983-10-03 1984-10-02 Process for preparing bbm-2478 antibiotic complex and components thereof, namely bbm-2478a and bbm-2478b antibiotics, further pharmaceutical compositions containing thereof

Country Status (29)

Country Link
US (1) US4518589A (enExample)
JP (2) JPS60115599A (enExample)
AT (1) AT381507B (enExample)
AU (1) AU570271B2 (enExample)
BE (1) BE900735A (enExample)
CA (1) CA1242159A (enExample)
CH (1) CH666043A5 (enExample)
CY (1) CY1534A (enExample)
DE (1) DE3436137C2 (enExample)
DK (1) DK473484A (enExample)
ES (1) ES8602135A1 (enExample)
FI (1) FI79141C (enExample)
FR (1) FR2555586B1 (enExample)
GB (1) GB2147582B (enExample)
GR (1) GR80551B (enExample)
HK (1) HK82790A (enExample)
HU (1) HU192461B (enExample)
IE (1) IE57825B1 (enExample)
IL (1) IL73126A (enExample)
IT (1) IT1176854B (enExample)
LU (1) LU85572A1 (enExample)
MX (1) MX9202848A (enExample)
MY (1) MY101664A (enExample)
NL (1) NL8403002A (enExample)
OA (1) OA07827A (enExample)
PT (1) PT79310B (enExample)
SE (1) SE460481B (enExample)
SU (1) SU1423001A3 (enExample)
ZA (1) ZA847723B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859598A (en) * 1984-03-26 1989-08-22 American Cyanamid Company Antibiotic LL-D42067β
US4626503A (en) * 1984-04-04 1986-12-02 American Cyanamid Company Antitumor agents LL-D49194α1, LL-D49194β1, LL-D49194β2, LL-D49194β3, LL-D49194γ, LL-D49194δ, LL-D49194ε, LL-D49194ξ, LL-D49194η, LL-D49194ω1, LL-D49194ω2, and LL-D49194ω3
CA1263645A (en) * 1984-04-27 1989-12-05 Hideo Sugi Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for producing the same
ATE72447T1 (de) * 1985-10-23 1992-02-15 Ishihara Sangyo Kaisha Chartreusinderivate und salze, diese enthaltende antitumorzusammensetzungen und verfahren zu ihrer herstellung.
DK0381114T3 (da) * 1989-01-30 1994-10-24 Ishihara Sangyo Kaisha Exo-3,4-O-benzyliden-3"-demethylchartreusin og salte deraf
IN172911B (enExample) * 1991-02-26 1994-01-01 Hoechst India
US5237055A (en) * 1991-05-30 1993-08-17 Bristol-Myers Squibb Company Chemical modification of 2"-amino group in elsamicin A
US5229371A (en) * 1991-05-30 1993-07-20 Bristol-Myers Squibb Company Chemical modification of elsamicin A at the 3' and/or 4' OH groups
HU210499B (en) * 1991-05-30 1995-04-28 Bristol Myers Squibb Co Process for preparing 6-o-alkylelsamicin a deriv.s and pharmaceutical compn.s contg. them
HU210162B (en) * 1991-05-30 1995-02-28 Bristol Myers Squibb Co Process for preparing 3',4'-o-substituted elsamicin a deriv.s and pharmaceutical compn.s contg. them
HU210492B (en) * 1991-05-30 1995-04-28 Bristol Myers Squibb Co Process for preparing novel 6-0-acyl deriv.s of elsamicin a and pharmaceutical copn.s contg. them
ZA923818B (en) * 1991-05-30 1993-11-25 Bristol Myers Squibb Co Chemical modification of 2"-amino group in elsamicin A
US5508268A (en) * 1993-08-12 1996-04-16 Bristol-Myers Squibb Parenteral elsamitrucin formulations
US20080181971A1 (en) * 2007-01-25 2008-07-31 Guru Reddy Combination Cancer Treatments Comprising Elsamitrucin and Other Agents
CN101472938A (zh) * 2007-05-24 2009-07-01 癌症治疗公司 适用于药物配制品的稳定的依沙芦星盐
KR20100101655A (ko) * 2007-12-19 2010-09-17 스펙트럼 파마슈티컬즈 인크 안정한 엘사미트루신 염 제제
JP2009207970A (ja) * 2008-03-03 2009-09-17 Marsima Aqua System Corp 空気揚水装置
CN111751469B (zh) * 2020-07-06 2022-06-14 江苏省中医院 一种液相色谱串联质谱测定血浆中教酒菌素浓度的方法

Also Published As

Publication number Publication date
CH666043A5 (de) 1988-06-30
SE8404929D0 (sv) 1984-10-02
PT79310B (en) 1986-11-14
JPH0689017B2 (ja) 1994-11-09
SE8404929L (sv) 1985-04-04
FI843823L (fi) 1985-04-04
FI79141B (fi) 1989-07-31
NL8403002A (nl) 1985-05-01
JPH0566394B2 (enExample) 1993-09-21
MX9202848A (es) 1992-06-30
AU570271B2 (en) 1988-03-10
JPS60115599A (ja) 1985-06-22
PT79310A (en) 1984-11-01
GB2147582A (en) 1985-05-15
HUT37170A (en) 1985-11-28
ES536455A0 (es) 1985-11-16
ATA313184A (de) 1986-03-15
OA07827A (fr) 1986-11-20
DE3436137A1 (de) 1985-05-15
JPH0641182A (ja) 1994-02-15
ZA847723B (en) 1985-05-29
BE900735A (fr) 1985-04-02
IT8422961A0 (it) 1984-10-03
GB8424810D0 (en) 1984-11-07
GR80551B (en) 1985-02-06
ES8602135A1 (es) 1985-11-16
AT381507B (de) 1986-10-27
US4518589A (en) 1985-05-21
IL73126A (en) 1989-05-15
SE460481B (sv) 1989-10-16
DE3436137C2 (de) 1993-12-02
IL73126A0 (en) 1984-12-31
LU85572A1 (fr) 1985-06-19
HK82790A (en) 1990-10-19
FR2555586A1 (fr) 1985-05-31
DK473484A (da) 1985-04-04
CY1534A (en) 1990-11-16
FI79141C (fi) 1989-11-10
DK473484D0 (da) 1984-10-02
FR2555586B1 (fr) 1988-10-07
IE842511L (en) 1985-04-03
IT8422961A1 (it) 1986-04-03
MY101664A (en) 1991-12-31
GB2147582B (en) 1987-04-15
IT1176854B (it) 1987-08-18
IE57825B1 (en) 1993-04-21
SU1423001A3 (ru) 1988-09-07
AU3354884A (en) 1986-09-11
CA1242159A (en) 1988-09-20
FI843823A0 (fi) 1984-09-28

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee