HU191095B - Process for the production of 3,5 diamino-1,2,4-triazole-derivatives - Google Patents

Process for the production of 3,5 diamino-1,2,4-triazole-derivatives Download PDF

Info

Publication number
HU191095B
HU191095B HU833145A HU314583A HU191095B HU 191095 B HU191095 B HU 191095B HU 833145 A HU833145 A HU 833145A HU 314583 A HU314583 A HU 314583A HU 191095 B HU191095 B HU 191095B
Authority
HU
Hungary
Prior art keywords
formula
compound
defined above
product
solvent
Prior art date
Application number
HU833145A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT34963A (en
Inventor
Jozsef Reiter
Peter Krajcsi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar,Hu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar,Hu filed Critical Egyt Gyogyszervegyeszeti Gyar,Hu
Priority to HU833145A priority Critical patent/HU191095B/hu
Priority to YU154784A priority patent/YU45654B/sh
Priority to CS846774A priority patent/CS244830B2/cs
Priority to ES535998A priority patent/ES535998A0/es
Priority to GB08422620A priority patent/GB2146331B/en
Priority to JP59186612A priority patent/JPS60100543A/ja
Priority to AT0287084A priority patent/AT389109B/de
Priority to IT22568/84A priority patent/IT1180224B/it
Priority to FI843527A priority patent/FI80685C/fi
Priority to DD84267111A priority patent/DD219767A5/de
Priority to FR8413763A priority patent/FR2551752B1/fr
Priority to SU843787351A priority patent/SU1480767A3/ru
Priority to DE19843433143 priority patent/DE3433143A1/de
Publication of HUT34963A publication Critical patent/HUT34963A/hu
Publication of HU191095B publication Critical patent/HU191095B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Herstellung von Dihydroaryloxyalkylamino-1,2,4-triazol-Derivaten der allgemeinen Formel I, worin R1 und R2 identisch oder verschieden sind und unabhaengig voneinander fuer Wasserstoff, C1-5 Alkyl, C2-5 Alkenyl, Aralkyl oder C3-7 Cycloalkyl stehen oder zusammen mit dem Stickstoffatom, an welches sie gebunden sind, einen 5-10-gliedrigen, gesaettigten oder mindestens eine Doppelbindung enthaltenden heterocyclischen Ring bilden und R3 C1-4 Alkyl oder C1-4 Hydroxyalkyl ist, und pharmazeutisch geeigneten Saeureadditionssalzen davon. Formel I
HU833145A 1983-09-09 1983-09-09 Process for the production of 3,5 diamino-1,2,4-triazole-derivatives HU191095B (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
HU833145A HU191095B (en) 1983-09-09 1983-09-09 Process for the production of 3,5 diamino-1,2,4-triazole-derivatives
YU154784A YU45654B (sh) 1983-09-09 1984-09-07 Postupak za dobivanje derivata dihidroariloksialkilamino-1,2,4-triazola
CS846774A CS244830B2 (en) 1983-09-09 1984-09-07 Production method of dihydroaryloxyalkylamine-1,2,4-triazole derivatives
ES535998A ES535998A0 (es) 1983-09-09 1984-09-07 Procedimiento de preparar derivados triazolicos
GB08422620A GB2146331B (en) 1983-09-09 1984-09-07 Process for the preparation of dihydroaryloxy-alkylamino-1,2,4-triazole derivatives
JP59186612A JPS60100543A (ja) 1983-09-09 1984-09-07 ジヒドロアリ−ルオキシアルキルアミノ−１，２，４−トリアゾ−ル誘導体の製法
AT0287084A AT389109B (de) 1983-09-09 1984-09-07 Verfahren zur herstellung von dihydroaryloxyalkylamino-1,2,4-triazol-derivate
IT22568/84A IT1180224B (it) 1983-09-09 1984-09-07 Procedimento per la preparazione di derivati di diidroarilossialchilammino-1,2,4-triazolo
FI843527A FI80685C (fi) 1983-09-09 1984-09-07 Foerfarande foer framstaellning av dihydroaryloxialkylamino-1,2,4-triazolderivat.
DD84267111A DD219767A5 (de) 1983-09-09 1984-09-07 Verfahren zur herstellung von dihydroaryloxyalkylamino-1,2,4-triazol-derivaten
FR8413763A FR2551752B1 (fr) 1983-09-09 1984-09-07 Procede de preparation de derives de dihydroaryloxyalcoylamino-1,2,4-triazole
SU843787351A SU1480767A3 (ru) 1983-09-09 1984-09-07 Способ получени производных дигидроарилокси алкиламино-1,2,4-триазола или их фармацевтически пригодных солей присоединени кислот
DE19843433143 DE3433143A1 (de) 1983-09-09 1984-09-10 Verfahren zur herstellung von 3-(amino)-5-(5'-(aminomethyl)-cyclohexa-1',4'-dien-1'-(yloxypropylamino))-1h-1,2,4-triazolderivaten sowie 5-(aminomethyl)-cyclohexa-1,4-dien-1-(yloxypropylamine) und ((5-(aminomethyl)-cyclohexa-1,4-dien-1-(yloxypropylamino))-(n-(cyan)-imino)-methyl)-(methyl)-thioaether

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU833145A HU191095B (en) 1983-09-09 1983-09-09 Process for the production of 3,5 diamino-1,2,4-triazole-derivatives

Publications (2)

Publication Number Publication Date
HUT34963A HUT34963A (en) 1985-05-28
HU191095B true HU191095B (en) 1987-01-28

Family

ID=10962781

Family Applications (1)

Application Number Title Priority Date Filing Date
HU833145A HU191095B (en) 1983-09-09 1983-09-09 Process for the production of 3,5 diamino-1,2,4-triazole-derivatives

Country Status (13)

Country Link
JP (1) JPS60100543A (de)
AT (1) AT389109B (de)
CS (1) CS244830B2 (de)
DD (1) DD219767A5 (de)
DE (1) DE3433143A1 (de)
ES (1) ES535998A0 (de)
FI (1) FI80685C (de)
FR (1) FR2551752B1 (de)
GB (1) GB2146331B (de)
HU (1) HU191095B (de)
IT (1) IT1180224B (de)
SU (1) SU1480767A3 (de)
YU (1) YU45654B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19848649C5 (de) 1998-10-22 2008-11-27 Peter Greiner Kohlenstoffkolben für eine Brennkraftmaschine
EP4196793A1 (de) 2020-08-11 2023-06-21 Université de Strasbourg Auf lebermakrophagen abzielende h2-blocker zur prävention und behandlung von lebererkrankungen und krebs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU538818B2 (en) * 1979-10-22 1984-08-30 Glaxo Group Limited 1-h-1,2,4-triazole compounds
DK558181A (da) * 1981-01-30 1982-07-31 Smithkline Corp Fremgangsmaade til fremstilling af 3,5-diamino-1,2,4-triazoler

Also Published As

Publication number Publication date
DE3433143A1 (de) 1985-03-28
FI80685B (fi) 1990-03-30
IT1180224B (it) 1987-09-23
YU154784A (en) 1986-12-31
IT8422568A0 (it) 1984-09-07
AT389109B (de) 1989-10-25
HUT34963A (en) 1985-05-28
ES8600258A1 (es) 1985-10-16
ES535998A0 (es) 1985-10-16
ATA287084A (de) 1989-03-15
GB2146331B (en) 1987-05-13
GB8422620D0 (en) 1984-10-10
GB2146331A (en) 1985-04-17
CS244830B2 (en) 1986-08-14
FI843527L (fi) 1985-03-10
FI843527A0 (fi) 1984-09-07
JPS60100543A (ja) 1985-06-04
YU45654B (sh) 1992-07-20
SU1480767A3 (ru) 1989-05-15
DD219767A5 (de) 1985-03-13
FI80685C (fi) 1990-07-10
FR2551752B1 (fr) 1987-04-24
FR2551752A1 (fr) 1985-03-15

Similar Documents

Publication Publication Date Title
EP0329397B1 (de) Verfahren zur Herstellung von Azolylmethyl-cyclopentanol-Derivaten
US3254093A (en) Process for preparing pyrazoles
KR19990036174A (ko) 케톤에 유기 금속을 첨가함에 의한 트리아졸의 제조 방법 및 그를 위한 중간체
US4668786A (en) P-fluorobenzoyl-piperidino alkyl theophylline derivatives
HU191095B (en) Process for the production of 3,5 diamino-1,2,4-triazole-derivatives
US4574155A (en) Process for preparing 2-hydrazino-1,3-diazacycloalk-2-ene hydrohalides
HU195773B (en) Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid
US3139455A (en) Phenoxyacetamidoximes
KR830002837B1 (ko) 아실-1h-1, 2, 4-트리아졸 유도체의 제조방법
EP0500952B1 (de) Verfahren zur herstellung eines stickstoffhaltigen heterozyklus
JP2578797B2 (ja) Ｎ−（スルホニルメチル）ホルムアミド類の製造法
US2436685A (en) Substituted piperazines
EP0033214A2 (de) Verfahren zur Herstellung therapeutisch aktiver Triazole
EP0329691B1 (de) Cardiotonische imidazolylphenylpyrrol-2-one
US3119832A (en) Certain z-aryl-x-isoxazoline
SU927113A3 (ru) Способ получени производных пиридиламина
JPH062747B2 (ja) ２‐アルキル‐４，５‐ジヒドロキシメチルイミダゾールの製法
CA1119179A (en) Process for preparing n-tritylimidazole compounds
SU922108A1 (ru) Способ получени производных 6-метил-8 @ -гидразинометилэрголина или их солей
JPS63196569A (ja) 光学活性２−ヒドロキシエチル−アゾール誘導体の製造方法
US4892956A (en) 5-cyano-4,5-dihydro-3,4-dicarboxypyrazole derivatives
US2785173A (en) Dialkylaminoalkylphenetidinopyridine quaternary ammonium salts
KR810000234B1 (ko) 벤조 아제핀계 유도체의 제조방법
JPS59205365A (ja) ４―アセチル―２―置換―イミダゾール化合物の製造方法
US4924001A (en) Process for preparing 5-cyano-4, 5-dihydro-3,4-dicarboxypyrazole derivatives

Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee