HU190716B - Process for preparing antibiotics containing carbapenemic skeleton - Google Patents

Process for preparing antibiotics containing carbapenemic skeleton Download PDF

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Publication number
HU190716B
HU190716B HU831201A HU120183A HU190716B HU 190716 B HU190716 B HU 190716B HU 831201 A HU831201 A HU 831201A HU 120183 A HU120183 A HU 120183A HU 190716 B HU190716 B HU 190716B
Authority
HU
Hungary
Prior art keywords
formula
compounds
group
alkyl
compound
Prior art date
Application number
HU831201A
Other languages
English (en)
Hungarian (hu)
Inventor
Uen K Choung
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of HU190716B publication Critical patent/HU190716B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU831201A 1982-04-08 1983-04-07 Process for preparing antibiotics containing carbapenemic skeleton HU190716B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36662782A 1982-04-08 1982-04-08

Publications (1)

Publication Number Publication Date
HU190716B true HU190716B (en) 1986-10-28

Family

ID=23443823

Family Applications (1)

Application Number Title Priority Date Filing Date
HU831201A HU190716B (en) 1982-04-08 1983-04-07 Process for preparing antibiotics containing carbapenemic skeleton

Country Status (25)

Country Link
JP (1) JPS58188887A (fr)
KR (1) KR880001055B1 (fr)
AT (1) AT383126B (fr)
AU (1) AU567092B2 (fr)
BE (1) BE896407A (fr)
CA (1) CA1198440A (fr)
CH (1) CH661927A5 (fr)
DE (1) DE3312517A1 (fr)
DK (1) DK155983A (fr)
ES (1) ES521224A0 (fr)
FI (1) FI74009C (fr)
FR (1) FR2524888B1 (fr)
GB (1) GB2118183B (fr)
GR (1) GR78822B (fr)
HU (1) HU190716B (fr)
IE (1) IE55225B1 (fr)
IL (1) IL68295A0 (fr)
IT (1) IT1168854B (fr)
LU (1) LU84739A1 (fr)
MY (1) MY8700945A (fr)
NL (1) NL8301193A (fr)
OA (1) OA07395A (fr)
PT (1) PT76518B (fr)
SE (1) SE460197B (fr)
ZA (1) ZA832411B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683301A (en) * 1982-04-08 1987-07-28 Bristol-Myers Company Carbapenem antibiotics
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
AT396473B (de) * 1984-10-02 1993-09-27 Bristol Myers Squibb Co Verfahren zur herstellung von neuen carbapenemderivaten
US4665169A (en) * 1985-09-11 1987-05-12 Bristol-Myers Company Carbapenem antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0017992A1 (fr) * 1979-04-19 1980-10-29 Merck & Co. Inc. Acides 1-carbadéthiapén-2-èm-carboxyliques substitués en position 2 et 6, procédés pour les préparer, compositions pharmaceutiques antibiotiques les contenant et procédé pour préparer des intermédiaires
EP0038869A1 (fr) * 1980-04-30 1981-11-04 Merck & Co. Inc. Procédé de préparation de 1-carbapénèmes et intermédiaires pour leur préparation
HU185493B (en) * 1981-12-30 1985-02-28 Richter Gedeon Vegyeszet Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics

Also Published As

Publication number Publication date
ZA832411B (en) 1983-12-28
PT76518B (en) 1986-02-06
AU1319883A (en) 1983-10-13
SE8301928L (sv) 1983-12-02
MY8700945A (en) 1987-12-31
IL68295A0 (en) 1983-07-31
CA1198440A (fr) 1985-12-24
IT8348061A0 (it) 1983-04-07
IE830800L (en) 1983-10-08
AT383126B (de) 1987-05-25
GB2118183A (en) 1983-10-26
IE55225B1 (en) 1990-07-04
KR880001055B1 (ko) 1988-06-18
DK155983D0 (da) 1983-04-07
SE460197B (sv) 1989-09-18
GB2118183B (en) 1985-11-27
FI74009B (fi) 1987-08-31
DE3312517C2 (fr) 1991-10-31
PT76518A (en) 1983-05-01
CH661927A5 (de) 1987-08-31
FI74009C (fi) 1987-12-10
JPS58188887A (ja) 1983-11-04
BE896407A (fr) 1983-10-07
GR78822B (fr) 1984-10-02
OA07395A (fr) 1984-06-30
FR2524888B1 (fr) 1985-12-13
JPH0524156B2 (fr) 1993-04-06
SE8301928D0 (sv) 1983-04-07
FI831135A0 (fi) 1983-04-05
ES8405399A1 (es) 1984-06-01
ES521224A0 (es) 1984-06-01
FI831135L (fi) 1983-10-09
DE3312517A1 (de) 1983-10-20
FR2524888A1 (fr) 1983-10-14
NL8301193A (nl) 1983-11-01
ATA125583A (de) 1986-10-15
DK155983A (da) 1983-10-09
LU84739A1 (fr) 1983-12-05
GB8309505D0 (en) 1983-05-11
AU567092B2 (en) 1987-11-12
KR840004429A (ko) 1984-10-15
IT1168854B (it) 1987-05-20

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628