HU189712B - Process for preparing new cef-3-em-carboxylic acid derivatives with antibiotic activity - Google Patents

Process for preparing new cef-3-em-carboxylic acid derivatives with antibiotic activity Download PDF

Info

Publication number
HU189712B
HU189712B HU832485A HU248583A HU189712B HU 189712 B HU189712 B HU 189712B HU 832485 A HU832485 A HU 832485A HU 248583 A HU248583 A HU 248583A HU 189712 B HU189712 B HU 189712B
Authority
HU
Hungary
Prior art keywords
ppm
formula
group
compound
carboxylic acid
Prior art date
Application number
HU832485A
Other languages
English (en)
Hungarian (hu)
Inventor
Bernard Labeeuw
Ali Salhi
Original Assignee
Sanofi,Fr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi,Fr filed Critical Sanofi,Fr
Publication of HU189712B publication Critical patent/HU189712B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HU832485A 1982-07-13 1983-07-12 Process for preparing new cef-3-em-carboxylic acid derivatives with antibiotic activity HU189712B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8212317A FR2530248A1 (fr) 1982-07-13 1982-07-13 Nouveaux derives des cephalosporines, leur procede de preparation et medicaments antibiotiques contenant lesdits derives

Publications (1)

Publication Number Publication Date
HU189712B true HU189712B (en) 1986-07-28

Family

ID=9275967

Family Applications (1)

Application Number Title Priority Date Filing Date
HU832485A HU189712B (en) 1982-07-13 1983-07-12 Process for preparing new cef-3-em-carboxylic acid derivatives with antibiotic activity

Country Status (28)

Country Link
US (1) US4578377A (xx)
EP (1) EP0099297B1 (xx)
JP (1) JPS5973590A (xx)
KR (1) KR840005455A (xx)
AT (1) ATE33392T1 (xx)
AU (1) AU555185B2 (xx)
CA (1) CA1209126A (xx)
CS (1) CS236797B2 (xx)
DD (1) DD210054A5 (xx)
DE (1) DE3376213D1 (xx)
DK (1) DK323183A (xx)
EG (1) EG15964A (xx)
ES (1) ES524040A0 (xx)
FI (1) FI74286C (xx)
FR (1) FR2530248A1 (xx)
GR (1) GR79285B (xx)
HU (1) HU189712B (xx)
IL (1) IL69210A (xx)
MA (1) MA19841A1 (xx)
NO (1) NO832515L (xx)
NZ (1) NZ204873A (xx)
OA (1) OA07495A (xx)
PH (1) PH19298A (xx)
PL (1) PL141582B1 (xx)
PT (1) PT77017B (xx)
SU (1) SU1194280A3 (xx)
YU (1) YU149683A (xx)
ZA (1) ZA835101B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855420A (en) * 1983-06-03 1989-08-08 Ici Pharma Cephalosporin derivatives
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
EP0333082A3 (en) * 1988-03-15 1991-05-02 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
JPH0320265A (ja) * 1989-02-10 1991-01-29 Meiji Seika Kaisha Ltd アミノチアゾール酢酸誘導体並びにその製造法
US9689021B2 (en) * 2011-10-14 2017-06-27 Université de Liège Method for measuring beta-lactam antibiotics

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK128611B (da) * 1961-05-16 1974-06-04 Glaxo Lab Ltd Fremgangsmåde til fremstilling af derivater af cephalosporin C eller salte deraf.
GB1012943A (en) * 1961-05-16 1965-12-15 Glaxo Lab Ltd Improvements in or relating to antibiotics
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
FR2442240A1 (fr) * 1978-11-27 1980-06-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique comportant un groupement eliminable sur le radical amino, leur procede de preparation et leur application a la synthese de produits actifs comme medicaments

Also Published As

Publication number Publication date
DK323183D0 (da) 1983-07-13
PL141582B1 (en) 1987-08-31
PT77017A (fr) 1983-08-01
YU149683A (en) 1985-10-31
CA1209126A (en) 1986-08-05
ATE33392T1 (de) 1988-04-15
DK323183A (da) 1984-01-14
FR2530248A1 (fr) 1984-01-20
JPS5973590A (ja) 1984-04-25
FI74286B (fi) 1987-09-30
PL242988A1 (en) 1984-08-13
IL69210A (en) 1986-12-31
EP0099297B1 (fr) 1988-04-06
FI832522L (fi) 1984-01-14
EP0099297A1 (fr) 1984-01-25
CS236797B2 (en) 1985-05-15
ZA835101B (en) 1984-03-28
ES8405412A1 (es) 1984-06-16
ES524040A0 (es) 1984-06-16
EG15964A (en) 1986-06-30
FR2530248B1 (xx) 1985-02-15
FI74286C (fi) 1988-01-11
DD210054A5 (de) 1984-05-30
SU1194280A3 (ru) 1985-11-23
IL69210A0 (en) 1983-11-30
OA07495A (fr) 1985-03-31
US4578377A (en) 1986-03-25
AU555185B2 (en) 1986-09-18
NO832515L (no) 1984-01-16
MA19841A1 (fr) 1984-04-01
AU1679583A (en) 1984-01-19
KR840005455A (ko) 1984-11-12
PT77017B (fr) 1986-01-24
FI832522A0 (fi) 1983-07-11
PH19298A (en) 1986-03-05
DE3376213D1 (en) 1988-05-11
GR79285B (xx) 1984-10-22
NZ204873A (en) 1985-12-13

Similar Documents

Publication Publication Date Title
HU182567B (en) Prcess for preparing new oxime derivatives of 3-acetoxymethyl-7-amino-thiazolyl-acetamido-cef-3-em-4-carboxylic acid
RU2183212C2 (ru) Антибактериальные цефалоспорины, фармацевтическая композиция на их основе и способ лечения
HU190541B (en) Process for preparing disubstituted proline derivatives
SU845789A3 (ru) Способ получени -7- -(4-окси-6-метил-НиКОТиНАМидО)- -(4-ОКСифЕНил)АцЕТАМидО -3- (1-МЕТилТЕТРАзОл-5-ил)ТиОМЕТил-3-цЕфЕМ-4-КАРбО-НОВОй КиСлОТы
HU189712B (en) Process for preparing new cef-3-em-carboxylic acid derivatives with antibiotic activity
US4263302A (en) Quinolinecarboxylic acid substituted penicillins and pharmaceutical compositions containing the same
CZ286394A3 (en) Salts of clavulanic acid with diamines, process of their preparation, and pharmaceutical compositions based thereon, use of such salts for preparing clavulanic acid or their pharmaceutically acceptable salts or esters and purification method of the latter compounds
HU191658B (en) Process for producing cepheme-carboxylic acid derivatives
US3655658A (en) 7(alpha-amino-alpha-phenylacetamido)-cephalosporanate esters
US4089963A (en) Esters of amidinopenicillanic acids, pharmaceutical preparations and method for treating infectious diseases
KR0178957B1 (ko) 페넴 화합물
JPS58103392A (ja) ３位においてチオメチルヘテロ環基により置換されたセフアロスポリンの新規な誘導体、これら化合物の製造方法およびこれらを含有する薬学的組成物
ES2203955T3 (es) 7-acilamino-3-(metilhidrazono)metil-cefalosporinas sustituidas antibacterianas y productos intermedios.
IE51358B1 (en) 1,2,4-triazinylthiomethyl-3-cephem sulfoxides,process for their preparation and pharmaceutical compositions containing them
US4301161A (en) Cephalosporin derivatives
US3847913A (en) Cephalosporanic acid esters
US4103011A (en) Novel penicillin compounds and process for preparation thereof
EP0122157A2 (en) Improvements in or relating to indolylglycyl cephalosporin derivatives
KR0177844B1 (ko) 항균성 페넴화합물
AU605635B2 (en) Monohydrate and solvates of a new beta-lactam antibiotic
AU597748B2 (en) Novel cephalosporin derivatives with improved pharmacokinetics, process for their preparation and pharmaceutical compositions in which they are present
US3296250A (en) 4-thiazolylmethylpenicillins
ES2268429T3 (es) Cefalosporinas.
ISAKA et al. Lactol esters of ampicillin
HU184788B (en) Process for the preparation of 7alfa-methoxy-ceph-3-em-4-carboxylic acid derivatives