HU186385B - Process for preparing new pyrido-indoles and pharmaceutical compositions containing thereof - Google Patents
Process for preparing new pyrido-indoles and pharmaceutical compositions containing thereof Download PDFInfo
- Publication number
- HU186385B HU186385B HU81531A HU53181A HU186385B HU 186385 B HU186385 B HU 186385B HU 81531 A HU81531 A HU 81531A HU 53181 A HU53181 A HU 53181A HU 186385 B HU186385 B HU 186385B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- group
- salt
- alk
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Gasification And Melting Of Waste (AREA)
- Dental Preparations (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Carbon And Carbon Compounds (AREA)
Abstract
Neue Amidine, insbesondere N,N' -ueberbrueckte Carbonsaeureamidine der allgemeinen Formel I, worin R tief 1 einen aromatischen Rest bedeutet, R tief 2 gegebenenfalls verestertes oder amidiertes 1-Carboxyniederalkyl darstellt, Ph gegebenenfalls substituiertes 1,2-Phenylen bedeutet und alk fuer einen die Iminogruppe von der Methingruppe durch 1 bis 3 C-Atome trennenden aliphatischen Kohlenwasserstoffrest steht, und ihre Salze, haben u.a. antiinflammatorische Wirkung und koennen in pharmazeutischen Praeparaten als Arzneimittelwirkstoff verwendet werden. Sie werden nach an sich bekannten Methoden hergestellt.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH170380 | 1980-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU186385B true HU186385B (en) | 1985-07-29 |
Family
ID=4216625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU81531A HU186385B (en) | 1980-03-04 | 1981-03-03 | Process for preparing new pyrido-indoles and pharmaceutical compositions containing thereof |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0035474B1 (de) |
| JP (1) | JPS56138188A (de) |
| KR (5) | KR850000045B1 (de) |
| AT (1) | ATE13673T1 (de) |
| AU (1) | AU544236B2 (de) |
| CA (1) | CA1161433A (de) |
| CY (1) | CY1340A (de) |
| DD (1) | DD156599A5 (de) |
| DE (1) | DE3170801D1 (de) |
| DK (1) | DK157757C (de) |
| ES (3) | ES499973A0 (de) |
| FI (1) | FI74007C (de) |
| GB (1) | GB2070608B (de) |
| GR (1) | GR74470B (de) |
| HK (1) | HK80086A (de) |
| HU (1) | HU186385B (de) |
| IE (1) | IE50985B1 (de) |
| IL (1) | IL62249A (de) |
| KE (1) | KE3646A (de) |
| MY (1) | MY8600361A (de) |
| NO (1) | NO156012C (de) |
| NZ (1) | NZ196393A (de) |
| PT (1) | PT72597B (de) |
| ZA (1) | ZA811398B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444768A (en) * | 1980-03-04 | 1984-04-24 | Ciba-Geigy Corporation | Pyrimido[1,6-a]indoles, pharmaceutical preparations containing them, and methods of treating pain and inflammation with them |
| DE3270406D1 (en) * | 1981-08-03 | 1986-05-15 | Ciba Geigy Ag | Amidines, process for their preparation, pharmaceutical compounds containing them and their use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4307234A (en) * | 1978-09-11 | 1981-12-22 | American Home Products Corp. | Pyrimido[1,6-a]indole derivatives |
-
1981
- 1981-02-26 AT AT81810064T patent/ATE13673T1/de active
- 1981-02-26 DE DE8181810064T patent/DE3170801D1/de not_active Expired
- 1981-02-26 EP EP81810064A patent/EP0035474B1/de not_active Expired
- 1981-02-27 DD DD81227945A patent/DD156599A5/de not_active IP Right Cessation
- 1981-03-02 PT PT198172597A patent/PT72597B/pt unknown
- 1981-03-02 GR GR64268A patent/GR74470B/el unknown
- 1981-03-02 FI FI810647A patent/FI74007C/fi not_active IP Right Cessation
- 1981-03-02 IL IL62249A patent/IL62249A/xx unknown
- 1981-03-02 CA CA000372095A patent/CA1161433A/en not_active Expired
- 1981-03-02 ES ES499973A patent/ES499973A0/es active Granted
- 1981-03-03 ZA ZA00811398A patent/ZA811398B/xx unknown
- 1981-03-03 AU AU68016/81A patent/AU544236B2/en not_active Ceased
- 1981-03-03 NO NO810719A patent/NO156012C/no unknown
- 1981-03-03 DK DK095081A patent/DK157757C/da not_active IP Right Cessation
- 1981-03-03 IE IE455/81A patent/IE50985B1/en not_active IP Right Cessation
- 1981-03-03 CY CY1340A patent/CY1340A/xx unknown
- 1981-03-03 HU HU81531A patent/HU186385B/hu unknown
- 1981-03-03 NZ NZ96393A patent/NZ196393A/xx unknown
- 1981-03-04 KR KR1019810000711A patent/KR850000045B1/ko active
- 1981-03-04 JP JP3001481A patent/JPS56138188A/ja active Granted
- 1981-05-03 GB GB8106589A patent/GB2070608B/en not_active Expired
-
1982
- 1982-02-16 ES ES509645A patent/ES509645A0/es active Granted
- 1982-07-30 ES ES514590A patent/ES514590A0/es active Granted
-
1984
- 1984-08-27 KR KR1019840005217A patent/KR850000062B1/ko not_active IP Right Cessation
- 1984-08-27 KR KR1019840005218A patent/KR850000044B1/ko not_active IP Right Cessation
- 1984-08-27 KR KR1019840005216A patent/KR850000061B1/ko not_active IP Right Cessation
- 1984-08-27 KR KR1019840005215A patent/KR850000060B1/ko not_active IP Right Cessation
-
1986
- 1986-06-11 KE KE3646A patent/KE3646A/xx unknown
- 1986-10-23 HK HK800/86A patent/HK80086A/xx unknown
- 1986-12-30 MY MY361/86A patent/MY8600361A/xx unknown
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