HRP970274A2 - Fluorinated vitamin d3 analogs - Google Patents

Fluorinated vitamin d3 analogs

Info

Publication number
HRP970274A2
HRP970274A2 HR60/018,187A HRP970274A HRP970274A2 HR P970274 A2 HRP970274 A2 HR P970274A2 HR P970274 A HRP970274 A HR P970274A HR P970274 A2 HRP970274 A2 HR P970274A2
Authority
HR
Croatia
Prior art keywords
analogs
fluorinated vitamin
fluorinated
vitamin
Prior art date
Application number
HR60/018,187A
Other languages
English (en)
Inventor
Bernard Michael Hennessy
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HRP970274A2 publication Critical patent/HRP970274A2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR60/018,187A 1996-05-23 1997-05-20 Fluorinated vitamin d3 analogs HRP970274A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1818796P 1996-05-23 1996-05-23

Publications (1)

Publication Number Publication Date
HRP970274A2 true HRP970274A2 (en) 1998-04-30

Family

ID=21786696

Family Applications (1)

Application Number Title Priority Date Filing Date
HR60/018,187A HRP970274A2 (en) 1996-05-23 1997-05-20 Fluorinated vitamin d3 analogs

Country Status (30)

Country Link
US (1) US5888994A (fr)
EP (1) EP0808831B1 (fr)
JP (1) JP2858571B2 (fr)
KR (1) KR100237523B1 (fr)
CN (1) CN1081184C (fr)
AR (1) AR007240A1 (fr)
AT (1) ATE195514T1 (fr)
AU (1) AU720098B2 (fr)
BR (1) BR9703373A (fr)
CA (1) CA2204478C (fr)
CO (1) CO4840512A1 (fr)
CZ (1) CZ157997A3 (fr)
DE (1) DE69702812T2 (fr)
DK (1) DK0808831T3 (fr)
ES (1) ES2150719T3 (fr)
GR (1) GR3034832T3 (fr)
HR (1) HRP970274A2 (fr)
HU (1) HUP9700927A3 (fr)
IL (1) IL120842A0 (fr)
MA (1) MA24345A1 (fr)
NO (1) NO971934L (fr)
NZ (1) NZ314838A (fr)
PL (1) PL320131A1 (fr)
PT (1) PT808831E (fr)
SG (1) SG50831A1 (fr)
TR (1) TR199700418A2 (fr)
TW (1) TW374762B (fr)
UY (1) UY24563A1 (fr)
YU (1) YU19997A (fr)
ZA (1) ZA974334B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
US6100294A (en) 1997-05-16 2000-08-08 Women And Infants Hospital Cyclic ether vitamin D3 compounds, 1α(OH) 3-epi-vitamin D3 compounds and uses thereof
EP0981514B1 (fr) * 1997-05-16 2006-04-05 Woman & Infants Hospital Composes de 3-epi-vitamine d2 et utilisations desdits composes
JP4219553B2 (ja) * 1997-09-08 2009-02-04 エフ.ホフマン−ラ ロシュ アーゲー 1,3−ジヒドロキシ−20,20−ジアルキル−ビタミンd3類似体
WO2000051554A2 (fr) * 1999-03-05 2000-09-08 Johns Hopkins University Regulation de l'aspect de la peau et composition contenant un compose d'analogue de vitamine d3 fluore
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
AU2005303773A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer
DK1993559T3 (en) 2006-02-03 2016-10-03 Opko Renal Llc Treatment of vitamin D deficiency and MALFUNCTION with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 d 부족 및 결핍의 치료 방법
DK2481400T3 (da) 2007-04-25 2014-09-29 Opko Ip Holdings Ii Inc Orale præparater med kontrolleret frigivelse omfattende en vitamin D-forbindelse og en voksagtig bærer
CN105796530A (zh) 2010-03-29 2016-07-27 赛特克罗公司 用于降低甲状旁腺水平的方法和组合物
WO2012065050A1 (fr) 2010-11-12 2012-05-18 Wisconsin Alumni Research Foundation Analogues 22-haloacétoxy-homoprégnacalciférol et leurs utilisations
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
IL290855B2 (en) 2016-03-28 2024-06-01 Eirgen Pharma Ltd Treatment methods using vitamin D

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039671A (en) * 1984-12-19 1991-08-13 Hoffmann-La Roche Inc. Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
US5210237A (en) * 1991-08-27 1993-05-11 Daikin Industries, Ltd. Vitamin d3 analogues
US5200536A (en) * 1992-02-10 1993-04-06 Daikin Industries Ltd. Fluorine-containing vitamin D3 analogues
GB9206648D0 (en) * 1992-03-26 1992-05-06 Leo Pharm Prod Ltd Chemical compounds
ATE141914T1 (de) * 1992-05-20 1996-09-15 Hoffmann La Roche Fluorierte analoge vitamins d3
CA2096105A1 (fr) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Analogues fluores de vitamine d3
TW267161B (fr) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger

Also Published As

Publication number Publication date
DK0808831T3 (da) 2001-01-02
EP0808831A3 (fr) 1999-02-03
GR3034832T3 (en) 2001-02-28
ATE195514T1 (de) 2000-09-15
ZA974334B (en) 1997-11-24
YU19997A (sh) 1999-07-28
HUP9700927A3 (en) 1999-07-28
TR199700418A3 (tr) 1997-12-21
CN1081184C (zh) 2002-03-20
UY24563A1 (es) 2000-12-29
TR199700418A2 (xx) 1997-12-21
DE69702812D1 (de) 2000-09-21
CN1169425A (zh) 1998-01-07
CA2204478C (fr) 2006-11-21
SG50831A1 (en) 1998-07-20
AU2357297A (en) 1997-11-27
ES2150719T3 (es) 2000-12-01
JPH1045712A (ja) 1998-02-17
MA24345A1 (fr) 1998-07-01
JP2858571B2 (ja) 1999-02-17
BR9703373A (pt) 1998-09-15
HUP9700927A2 (hu) 1998-01-28
CO4840512A1 (es) 1999-09-27
IL120842A0 (en) 1997-09-30
CZ157997A3 (en) 1997-12-17
DE69702812T2 (de) 2001-01-25
PL320131A1 (en) 1997-11-24
HU9700927D0 (en) 1997-07-28
KR970074763A (ko) 1997-12-10
NZ314838A (en) 1998-01-26
KR100237523B1 (ko) 2000-01-15
TW374762B (en) 1999-11-21
PT808831E (pt) 2000-12-29
US5888994A (en) 1999-03-30
NO971934L (no) 1997-11-24
MX9703776A (es) 1998-06-30
AU720098B2 (en) 2000-05-25
NO971934D0 (no) 1997-04-25
EP0808831A2 (fr) 1997-11-26
AR007240A1 (es) 1999-10-27
EP0808831B1 (fr) 2000-08-16
CA2204478A1 (fr) 1997-11-23

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Legal Events

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A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
OBST Application withdrawn