HRP920384B1 - A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof - Google Patents

A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof

Info

Publication number
HRP920384B1
HRP920384B1 HRP-1498/91A HRP920384A HRP920384B1 HR P920384 B1 HRP920384 B1 HR P920384B1 HR P920384 A HRP920384 A HR P920384A HR P920384 B1 HRP920384 B1 HR P920384B1
Authority
HR
Croatia
Prior art keywords
acetal
hemi
preparation
intermediates
albuterol
Prior art date
Application number
HRP-1498/91A
Other languages
English (en)
Inventor
Junning Lee
Original Assignee
Junning Lee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Junning Lee filed Critical Junning Lee
Publication of HRP920384A2 publication Critical patent/HRP920384A2/hr
Publication of HRP920384B1 publication Critical patent/HRP920384B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
    • C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/022—Boron compounds without C-boron linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/04—Esters of boric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP-1498/91A 1990-09-11 1992-09-21 A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof HRP920384B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58070590A 1990-09-11 1990-09-11
YU149891A YU48672B (sh) 1990-09-11 1991-09-09 Bor-ariletanolamin kompleks, acetali i hemi acetali i postupak za dobivanje ariletanolamina, acetala, hemiacetala i hidrata arilglioksal intermedijera

Publications (2)

Publication Number Publication Date
HRP920384A2 HRP920384A2 (en) 1995-10-31
HRP920384B1 true HRP920384B1 (en) 1998-10-31

Family

ID=24322195

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-1498/91A HRP920384B1 (en) 1990-09-11 1992-09-21 A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof

Country Status (24)

Country Link
US (1) US5283359A (xx)
EP (1) EP0548224B1 (xx)
JP (2) JPH07113006B2 (xx)
KR (1) KR960006670B1 (xx)
CN (1) CN1051759C (xx)
AT (1) ATE114300T1 (xx)
AU (2) AU648114B2 (xx)
CA (2) CA2121914C (xx)
DE (2) DE69105277T2 (xx)
DK (1) DK0548224T3 (xx)
ES (1) ES2059288T3 (xx)
GR (1) GR930300087T1 (xx)
HR (1) HRP920384B1 (xx)
HU (1) HUT65809A (xx)
IE (1) IE66041B1 (xx)
IL (6) IL119476A (xx)
MX (1) MX9101019A (xx)
NZ (2) NZ239732A (xx)
PT (1) PT98906B (xx)
SI (1) SI9111498A (xx)
TW (1) TW363955B (xx)
WO (1) WO1992004314A2 (xx)
YU (1) YU48672B (xx)
ZA (1) ZA917150B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5442118A (en) * 1994-04-22 1995-08-15 Sepracor, Inc. Asymmetric synthesis of (R)- and (S)-arylethanolamines from iminoketones
US5399765A (en) * 1994-05-23 1995-03-21 Sepracor, Inc. Enantioselective preparation of optically pure albuterol
US5545745A (en) * 1994-05-23 1996-08-13 Sepracor, Inc. Enantioselective preparation of optically pure albuterol
CA2556904A1 (en) 2004-05-20 2005-12-01 Teva Harmaceutical Fine Chemicals S.R.L. Preparation of levalbuterol hydrochloride
US8070044B1 (en) * 2010-12-02 2011-12-06 Rohm And Haas Electronic Materials Llc Polyamine flux composition and method of soldering
US8070045B1 (en) * 2010-12-02 2011-12-06 Rohm And Haas Electronic Materials Llc Curable amine flux composition and method of soldering
KR102311735B1 (ko) 2014-11-25 2021-10-13 비 메디컬 시스템즈 에스.에이.알.엘. 냉각 장치
CN105001100A (zh) * 2015-06-11 2015-10-28 山西云鹏制药有限公司 一种精制硫酸沙丁胺醇的方法
WO2017195873A1 (ja) 2016-05-12 2017-11-16 サントリーホールディングス株式会社 Ｌ－ヒドロキシプロリンを含有する酵母ヤロウィア・リポリティカの菌体もしくは菌体培養物又はこれらの抽出物及びその用途並びにｌ－ヒドロキシプロリンの製造方法
CN106748824A (zh) * 2016-11-21 2017-05-31 河南工业大学 一种新的沙丁胺醇药物盐‑沙丁胺醇富马酸盐及其制备方法
CN108863819B (zh) * 2018-06-26 2021-01-15 南京逐陆医药科技有限公司 一种游离的消旋沙丁胺醇的制备方法
CN110734382B (zh) * 2019-10-09 2024-02-20 苏州弘森药业股份有限公司 一种合成特布他林的方法
CN112341373B (zh) * 2020-11-30 2022-04-08 山东嘉成医药科技有限公司 一种酞丁安的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
GB1214012A (en) * 1967-12-21 1970-11-25 Allen & Hanburys Ltd Phenylethanolamines
GB1247370A (en) * 1968-12-31 1971-09-22 Allen & Hanburys Ltd Glyoxals and production thereof
GB1266058A (xx) * 1969-07-08 1972-03-08
US3928293A (en) * 1974-04-01 1975-12-23 Dynapol Corp Polymeric reagent
US4029706A (en) * 1974-04-01 1977-06-14 Dynapol Reduction with polymeric reagent
DE2730462A1 (de) * 1976-07-15 1978-01-19 Ciba Geigy Ag Photoinitiatoren fuer uv-haertbare massen
EP0114389A3 (en) * 1983-01-20 1985-12-18 American Cyanamid Company Substituted arylglyoxal derivatives
JP2693988B2 (ja) * 1987-06-24 1997-12-24 キノイン ギオギスゼル エス ベギエスゼチ テルメケク ギヤラ アールティー． キノリンカルボン酸誘導体の製造方法

Also Published As

Publication number Publication date
US5283359A (en) 1994-02-01
CA2121914A1 (en) 1992-03-12
ZA917150B (en) 1992-05-27
PT98906B (pt) 1999-02-26
EP0548224A1 (en) 1993-06-30
HRP920384A2 (en) 1995-10-31
CA2121914C (en) 1998-09-29
DK0548224T3 (da) 1995-01-09
YU149891A (sh) 1994-01-20
CN1051759C (zh) 2000-04-26
GR930300087T1 (en) 1993-09-30
EP0548224B1 (en) 1994-11-23
TW363955B (en) 1999-07-11
CN1059904A (zh) 1992-04-01
JPH07113006B2 (ja) 1995-12-06
DE69105277T2 (de) 1995-04-06
IL99436A (en) 1999-03-12
NZ239732A (en) 1995-03-28
KR960006670B1 (ko) 1996-05-22
AU656287B2 (en) 1995-01-27
CA2091352C (en) 1996-12-03
IL119477A0 (en) 1997-01-10
CA2091352A1 (en) 1992-03-12
DE548224T1 (de) 1993-10-14
IL119476A (en) 1999-10-28
WO1992004314A2 (en) 1992-03-19
JPH07233115A (ja) 1995-09-05
HUT65809A (en) 1994-07-28
IL119477A (en) 1999-10-28
PT98906A (pt) 1992-09-30
HU9300684D0 (en) 1993-06-28
NZ248939A (en) 1995-03-28
YU48672B (sh) 1999-06-15
IL99436A0 (en) 1992-08-18
ATE114300T1 (de) 1994-12-15
JP3055757B2 (ja) 2000-06-26
IL115678A0 (en) 1996-01-19
MX9101019A (es) 1992-05-04
AU8617091A (en) 1992-03-30
IL115678A (en) 1998-01-04
AU648114B2 (en) 1994-04-14
SI9111498A (en) 1997-12-31
JPH05506668A (ja) 1993-09-30
AU5508694A (en) 1994-04-28
DE69105277D1 (de) 1995-01-05
ES2059288T3 (es) 1995-01-16
IE66041B1 (en) 1995-12-13
IL119476A0 (en) 1997-01-10
IE913174A1 (en) 1992-03-11
ES2059288T1 (es) 1994-11-16
WO1992004314A3 (en) 1992-05-29

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