JO1521B1 - Substituted aminopropionamides,a process for their preparation,agents containing them,and their use,and new intermediates produced in the preparation - Google Patents

Substituted aminopropionamides,a process for their preparation,agents containing them,and their use,and new intermediates produced in the preparation

Info

Publication number
JO1521B1
JO1521B1 JO19871521A JOP19871521A JO1521B1 JO 1521 B1 JO1521 B1 JO 1521B1 JO 19871521 A JO19871521 A JO 19871521A JO P19871521 A JOP19871521 A JO P19871521A JO 1521 B1 JO1521 B1 JO 1521B1
Authority
JO
Jordan
Prior art keywords
preparation
aminopropionamides
substituted
agents containing
new intermediates
Prior art date
Application number
JO19871521A
Other languages
Arabic (ar)
Inventor
كونستمان رودلف
هوك فرانز
ويمير جابريل
Original Assignee
هوكست اكتينجسلشافت
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by هوكست اكتينجسلشافت filed Critical هوكست اكتينجسلشافت
Application granted granted Critical
Publication of JO1521B1 publication Critical patent/JO1521B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Abstract

SUBSTITUTED AMINOPROPIONAMIDES,A PROCESS FOR THEIR PREPARATION,AGENTS CONTAINING THEM,AND THEIR USE,AND NEW INTERMEDIATES PRODUCED IN THE PREPARATION
JO19871521A 1986-12-12 1987-11-17 Substituted aminopropionamides,a process for their preparation,agents containing them,and their use,and new intermediates produced in the preparation JO1521B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863642497 DE3642497A1 (en) 1986-12-12 1986-12-12 SUBSTITUTED AMINOPROPIONIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR SUBSTANCES AND THEIR USE AND THE NEW INTERMEDIATES PRODUCED IN THE PRODUCTION

Publications (1)

Publication Number Publication Date
JO1521B1 true JO1521B1 (en) 1989-01-25

Family

ID=6316060

Family Applications (1)

Application Number Title Priority Date Filing Date
JO19871521A JO1521B1 (en) 1986-12-12 1987-11-17 Substituted aminopropionamides,a process for their preparation,agents containing them,and their use,and new intermediates produced in the preparation

Country Status (17)

Country Link
EP (1) EP0271099A3 (en)
JP (1) JPS63185948A (en)
KR (1) KR880007490A (en)
AU (1) AU8246087A (en)
DE (1) DE3642497A1 (en)
DK (1) DK651987A (en)
FI (1) FI875432A (en)
HU (1) HUT45486A (en)
IL (1) IL84791A0 (en)
JO (1) JO1521B1 (en)
MA (1) MA21130A1 (en)
MT (1) MTP1014B (en)
NO (1) NO875181D0 (en)
OA (1) OA08699A (en)
PT (1) PT86344B (en)
TN (1) TNSN87138A1 (en)
ZA (1) ZA879330B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039805A (en) * 1988-12-08 1991-08-13 Hoffmann-La Roche Inc. Novel benzoic and phenylacetic acid derivatives
US5149817A (en) * 1990-03-05 1992-09-22 Shionogi & Co., Ltd. Teirahydropyridine derivatives
US5189179A (en) 1990-08-29 1993-02-23 Merrell Dow Pharmaceuticals Inc. Serotonin 5ht1a agonists
AU3241093A (en) * 1992-01-07 1993-08-03 Merrell Dow Pharmaceuticals Inc. Treatment of involuntary movements with 5HT-1A receptor agonists
EP1118612A1 (en) * 2000-01-21 2001-07-25 Universita Degli Studi di Firenze Piperazine derivatives possesing nootropic activity
FR2976942B1 (en) * 2011-06-23 2013-07-12 Metabolys PIPERAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN THE TREATMENT OF INSULIN RESISTANCE
CN111116451A (en) * 2020-01-16 2020-05-08 宁波大学 Polysubstituted tryptophane benzamide compound and preparation method and application thereof
CN115322131B (en) * 2022-04-21 2023-08-22 温州大学 Synthesis method of beta-fluoroindole acrylamide compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8303946D0 (en) * 1983-02-12 1983-03-16 Recordati Chem Pharm Antihypertensive n-piperazinylalkanoylanilides
DE3500898A1 (en) * 1985-01-12 1986-07-17 Hoechst Ag, 6230 Frankfurt Novel propionamides having acid-secretion-inhibiting action, process for their preparation, compositions containing them, and their use

Also Published As

Publication number Publication date
AU8246087A (en) 1988-08-18
PT86344A (en) 1988-01-01
DK651987A (en) 1988-06-13
FI875432A (en) 1988-06-13
MA21130A1 (en) 1988-07-01
ZA879330B (en) 1988-07-27
EP0271099A3 (en) 1989-05-03
IL84791A0 (en) 1988-05-31
KR880007490A (en) 1988-08-27
FI875432A0 (en) 1987-12-10
NO875181D0 (en) 1987-12-11
HUT45486A (en) 1988-07-28
MTP1014B (en) 1989-07-18
TNSN87138A1 (en) 1990-01-01
PT86344B (en) 1990-11-07
DE3642497A1 (en) 1988-06-23
OA08699A (en) 1989-03-31
EP0271099A2 (en) 1988-06-15
JPS63185948A (en) 1988-08-01
DK651987D0 (en) 1987-12-11

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