DE69105277D1 - Verfahren zur herstellung von albuterol, sowie von arylglyoxal-, acetal-, hemiacetal- und hydrat-zwischenprodukten. - Google Patents
Verfahren zur herstellung von albuterol, sowie von arylglyoxal-, acetal-, hemiacetal- und hydrat-zwischenprodukten.Info
- Publication number
- DE69105277D1 DE69105277D1 DE69105277T DE69105277T DE69105277D1 DE 69105277 D1 DE69105277 D1 DE 69105277D1 DE 69105277 T DE69105277 T DE 69105277T DE 69105277 T DE69105277 T DE 69105277T DE 69105277 D1 DE69105277 D1 DE 69105277D1
- Authority
- DE
- Germany
- Prior art keywords
- acetal
- intermediates
- albuterol
- arylglyoxal
- hemiacetal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
- C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58070590A | 1990-09-11 | 1990-09-11 | |
PCT/US1991/006248 WO1992004314A2 (en) | 1990-09-11 | 1991-09-06 | Process for preparing albuterol, acetal, hemi-acetal, and hydrates of arylglyoxal intermediates thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69105277D1 true DE69105277D1 (de) | 1995-01-05 |
DE69105277T2 DE69105277T2 (de) | 1995-04-06 |
Family
ID=24322195
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69105277T Expired - Fee Related DE69105277T2 (de) | 1990-09-11 | 1991-09-06 | Verfahren zur herstellung von albuterol, sowie von arylglyoxal-, acetal-, hemiacetal- und hydrat-zwischenprodukten. |
DE91916922T Pending DE548224T1 (de) | 1990-09-11 | 1991-09-06 | Verfahren zur herstellung von albutero, sowie von arylglyoxal-, acetal-, hemiacetal- und hydrat-zwischenprodukten. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE91916922T Pending DE548224T1 (de) | 1990-09-11 | 1991-09-06 | Verfahren zur herstellung von albutero, sowie von arylglyoxal-, acetal-, hemiacetal- und hydrat-zwischenprodukten. |
Country Status (24)
Country | Link |
---|---|
US (1) | US5283359A (de) |
EP (1) | EP0548224B1 (de) |
JP (2) | JP3055757B2 (de) |
KR (1) | KR960006670B1 (de) |
CN (1) | CN1051759C (de) |
AT (1) | ATE114300T1 (de) |
AU (2) | AU648114B2 (de) |
CA (2) | CA2091352C (de) |
DE (2) | DE69105277T2 (de) |
DK (1) | DK0548224T3 (de) |
ES (1) | ES2059288T3 (de) |
GR (1) | GR930300087T1 (de) |
HR (1) | HRP920384B1 (de) |
HU (1) | HUT65809A (de) |
IE (1) | IE66041B1 (de) |
IL (6) | IL119477A (de) |
MX (1) | MX9101019A (de) |
NZ (2) | NZ248939A (de) |
PT (1) | PT98906B (de) |
SI (1) | SI9111498A (de) |
TW (1) | TW363955B (de) |
WO (1) | WO1992004314A2 (de) |
YU (1) | YU48672B (de) |
ZA (1) | ZA917150B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5442118A (en) * | 1994-04-22 | 1995-08-15 | Sepracor, Inc. | Asymmetric synthesis of (R)- and (S)-arylethanolamines from iminoketones |
US5399765A (en) * | 1994-05-23 | 1995-03-21 | Sepracor, Inc. | Enantioselective preparation of optically pure albuterol |
US5545745A (en) * | 1994-05-23 | 1996-08-13 | Sepracor, Inc. | Enantioselective preparation of optically pure albuterol |
EP1641741A1 (de) | 2004-05-20 | 2006-04-05 | Teva Pharmaceutical Fine Chemicals S.R.L. | Levalbuterol hydrochlorid polymorph b |
US8070045B1 (en) * | 2010-12-02 | 2011-12-06 | Rohm And Haas Electronic Materials Llc | Curable amine flux composition and method of soldering |
US8070044B1 (en) * | 2010-12-02 | 2011-12-06 | Rohm And Haas Electronic Materials Llc | Polyamine flux composition and method of soldering |
AU2014412384A1 (en) | 2014-11-25 | 2017-06-22 | B Medical Systems S.à r.l. | Cooling device |
CN105001100A (zh) * | 2015-06-11 | 2015-10-28 | 山西云鹏制药有限公司 | 一种精制硫酸沙丁胺醇的方法 |
CN109072171A (zh) | 2016-05-12 | 2018-12-21 | 三得利控股株式会社 | 含有l-羟脯氨酸的解脂耶氏酵母的菌体或菌体培养物或者它们的提取物及其用途以及l-羟脯氨酸的制造方法 |
CN106748824A (zh) * | 2016-11-21 | 2017-05-31 | 河南工业大学 | 一种新的沙丁胺醇药物盐‑沙丁胺醇富马酸盐及其制备方法 |
CN108863819B (zh) * | 2018-06-26 | 2021-01-15 | 南京逐陆医药科技有限公司 | 一种游离的消旋沙丁胺醇的制备方法 |
CN110734382B (zh) * | 2019-10-09 | 2024-02-20 | 苏州弘森药业股份有限公司 | 一种合成特布他林的方法 |
CN112341373B (zh) * | 2020-11-30 | 2022-04-08 | 山东嘉成医药科技有限公司 | 一种酞丁安的制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
GB1214012A (en) * | 1967-12-21 | 1970-11-25 | Allen & Hanburys Ltd | Phenylethanolamines |
GB1247370A (en) * | 1968-12-31 | 1971-09-22 | Allen & Hanburys Ltd | Glyoxals and production thereof |
GB1266058A (de) * | 1969-07-08 | 1972-03-08 | ||
US3928293A (en) * | 1974-04-01 | 1975-12-23 | Dynapol Corp | Polymeric reagent |
US4029706A (en) * | 1974-04-01 | 1977-06-14 | Dynapol | Reduction with polymeric reagent |
DE2730462A1 (de) * | 1976-07-15 | 1978-01-19 | Ciba Geigy Ag | Photoinitiatoren fuer uv-haertbare massen |
EP0114389A3 (de) * | 1983-01-20 | 1985-12-18 | American Cyanamid Company | Substituierte Arylglyoxal-Derivate |
KR970005911B1 (ko) * | 1987-06-24 | 1997-04-22 | 치노인 교기스져 에스 베게스제티 테르메케크 기야라 알티 | 퀴놀린 카복실산 유도체를 제조하는 제조방법 |
-
1991
- 1991-09-06 WO PCT/US1991/006248 patent/WO1992004314A2/en active IP Right Grant
- 1991-09-06 JP JP6303806A patent/JP3055757B2/ja not_active Expired - Lifetime
- 1991-09-06 DE DE69105277T patent/DE69105277T2/de not_active Expired - Fee Related
- 1991-09-06 IL IL11947791A patent/IL119477A/xx not_active IP Right Cessation
- 1991-09-06 HU HU9300684A patent/HUT65809A/hu unknown
- 1991-09-06 EP EP91916922A patent/EP0548224B1/de not_active Expired - Lifetime
- 1991-09-06 ES ES91916922T patent/ES2059288T3/es not_active Expired - Lifetime
- 1991-09-06 US US08/030,185 patent/US5283359A/en not_active Expired - Fee Related
- 1991-09-06 IL IL9943691A patent/IL99436A/en not_active IP Right Cessation
- 1991-09-06 AU AU86170/91A patent/AU648114B2/en not_active Ceased
- 1991-09-06 CA CA002091352A patent/CA2091352C/en not_active Expired - Fee Related
- 1991-09-06 CA CA002121914A patent/CA2121914C/en not_active Expired - Fee Related
- 1991-09-06 AT AT91916922T patent/ATE114300T1/de not_active IP Right Cessation
- 1991-09-06 DE DE91916922T patent/DE548224T1/de active Pending
- 1991-09-06 JP JP3515879A patent/JPH07113006B2/ja not_active Expired - Lifetime
- 1991-09-06 IL IL11947691A patent/IL119476A/xx not_active IP Right Cessation
- 1991-09-06 KR KR1019930700720A patent/KR960006670B1/ko not_active IP Right Cessation
- 1991-09-06 DK DK91916922.7T patent/DK0548224T3/da active
- 1991-09-09 SI SI9111498A patent/SI9111498A/sl unknown
- 1991-09-09 PT PT98906A patent/PT98906B/pt not_active IP Right Cessation
- 1991-09-09 YU YU149891A patent/YU48672B/sh unknown
- 1991-09-09 TW TW080107103A patent/TW363955B/zh active
- 1991-09-09 ZA ZA917150A patent/ZA917150B/xx unknown
- 1991-09-10 MX MX9101019A patent/MX9101019A/es not_active IP Right Cessation
- 1991-09-10 CN CN91108911A patent/CN1051759C/zh not_active Expired - Fee Related
- 1991-09-10 NZ NZ248939A patent/NZ248939A/en unknown
- 1991-09-10 IE IE317491A patent/IE66041B1/en not_active IP Right Cessation
- 1991-09-10 NZ NZ239732A patent/NZ239732A/en unknown
-
1992
- 1992-09-21 HR HRP-1498/91A patent/HRP920384B1/xx not_active IP Right Cessation
-
1993
- 1993-09-30 GR GR930300087T patent/GR930300087T1/el unknown
-
1994
- 1994-02-10 AU AU55086/94A patent/AU656287B2/en not_active Ceased
-
1995
- 1995-10-19 IL IL115678A patent/IL115678A/en not_active IP Right Cessation
-
1996
- 1996-10-23 IL IL11947696A patent/IL119476A0/xx unknown
- 1996-10-23 IL IL11947796A patent/IL119477A0/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE209168T1 (de) | Verfahren zur herstellung eines mineralwollerzeugnis | |
DE69105277D1 (de) | Verfahren zur herstellung von albuterol, sowie von arylglyoxal-, acetal-, hemiacetal- und hydrat-zwischenprodukten. | |
DE69125035D1 (de) | Verfahren zur herstellung von interferon-alpha-2 kristallen | |
ATE131843T1 (de) | Verfahren zur herstellung von organopolysiloxanharz | |
DE69104365T2 (de) | Vaterit und verfahren zu dessen herstellung. | |
ATE422900T1 (de) | Verfahren zur herstellung eines azellulären impfstoffes der bordetella pertussis antigene enthält | |
DE69403087T2 (de) | Verfahren zur herstellung von 9-(2-hydroxy)-ethoxy-guanin | |
DE68913394D1 (de) | Verfahren zur Herstellung von substituierten Phenoxyethylaminen sowie Zwischenverbindungen. | |
ATE148694T1 (de) | Verfahren zur herstellung von 3(5)- methylpyrazolen | |
ATE106853T1 (de) | Verfahren zur herstellung von metallhydroxiden mit geringer spezifischer oberfläche. | |
ATE189677T1 (de) | Verfahren zur herstellung von furosemide | |
ATE169912T1 (de) | Verfahren zur herstellung von 5-amino-1,3- dioxanen | |
DE58900748D1 (de) | Verfahren zur herstellung eines addukts aus 2-hydroxy-naphthalin-6-carbonsaeure und 1,4-dioxan und dessen verwendung. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |