HRP20200372T1 - Postupci proizvodnje poloksamera za upotrebu u mediju za staničnu kulturu - Google Patents
Postupci proizvodnje poloksamera za upotrebu u mediju za staničnu kulturu Download PDFInfo
- Publication number
- HRP20200372T1 HRP20200372T1 HRP20200372TT HRP20200372T HRP20200372T1 HR P20200372 T1 HRP20200372 T1 HR P20200372T1 HR P20200372T T HRP20200372T T HR P20200372TT HR P20200372 T HRP20200372 T HR P20200372T HR P20200372 T1 HRP20200372 T1 HR P20200372T1
- Authority
- HR
- Croatia
- Prior art keywords
- poloxamer
- minutes
- heated
- cell
- culture medium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
- C08G65/48—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/50—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing nitrogen, e.g. polyetheramines or Jeffamines(r)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/58—Ethylene oxide or propylene oxide copolymers, e.g. pluronics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Polyesters Or Polycarbonates (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461970281P | 2014-03-25 | 2014-03-25 | |
| EP15715932.8A EP3122799B8 (en) | 2014-03-25 | 2015-03-25 | Methods of preparing a poloxamer for use in cell culture medium |
| PCT/US2015/022592 WO2015148736A1 (en) | 2014-03-25 | 2015-03-25 | Methods of preparing a poloxamer for use in cell culture medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20200372T1 true HRP20200372T1 (hr) | 2020-06-12 |
Family
ID=52824596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20200372TT HRP20200372T1 (hr) | 2014-03-25 | 2015-03-25 | Postupci proizvodnje poloksamera za upotrebu u mediju za staničnu kulturu |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11034793B2 (https=) |
| EP (2) | EP3778702B1 (https=) |
| JP (3) | JP6655548B2 (https=) |
| KR (1) | KR102352250B1 (https=) |
| CN (2) | CN106414552B (https=) |
| AU (1) | AU2015236008B2 (https=) |
| BR (1) | BR112016021739B1 (https=) |
| CA (1) | CA2943357C (https=) |
| ES (1) | ES2778680T3 (https=) |
| HR (1) | HRP20200372T1 (https=) |
| IL (2) | IL247902B (https=) |
| MX (2) | MX2016012288A (https=) |
| MY (1) | MY178060A (https=) |
| PL (1) | PL3122799T3 (https=) |
| RU (1) | RU2710551C2 (https=) |
| SG (1) | SG11201607929PA (https=) |
| SI (1) | SI3122799T1 (https=) |
| WO (1) | WO2015148736A1 (https=) |
| ZA (1) | ZA201606711B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112016021739B1 (pt) | 2014-03-25 | 2021-11-03 | Genentech, Inc | Método para preparar um poloxâmero para uso em um meio de cultura de célula |
| EP3430072B1 (en) * | 2016-03-17 | 2020-07-01 | Merck Patent GmbH | Method for purifying poloxamers |
| JP7135096B2 (ja) * | 2017-12-21 | 2022-09-12 | シグマ－アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニー | ポロキサマー組成物ならびにその製造方法およびその使用 |
| EP3790597A4 (en) * | 2018-07-12 | 2022-03-09 | Arshintseva, Elena Valentinovna | THERMAL PROCESS FOR THE STERILIZATION OF POLOXAMER WITH LIQUID PHARMACEUTICALS |
| CN112469814A (zh) * | 2018-07-27 | 2021-03-09 | 味之素株式会社 | 动物细胞的悬浮培养用添加物、悬浮培养用培养基和悬浮培养方法 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE266710C (https=) | ||||
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| AU632065B2 (en) | 1988-09-23 | 1992-12-17 | Novartis Vaccines And Diagnostics, Inc. | Cell culture medium for enhanced cell growth, culture longevity and product expression |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
| EP1690934A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| US5531925A (en) | 1991-10-04 | 1996-07-02 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
| EP0754050B1 (en) | 1994-01-14 | 2002-06-26 | XOMA Technology Ltd. | Anti gram positive bacterial methods and materials |
| US5912228A (en) * | 1995-01-13 | 1999-06-15 | Xoma Corporation | Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products |
| CA2219361C (en) | 1995-04-27 | 2012-02-28 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
| EP1500329B1 (en) | 1996-12-03 | 2012-03-21 | Amgen Fremont Inc. | Human antibodies that specifically bind human TNF alpha |
| GB9625175D0 (en) * | 1996-12-04 | 1997-01-22 | Medi Cult As | Serum-free cell culture media |
| US5804420A (en) | 1997-04-18 | 1998-09-08 | Bayer Corporation | Preparation of recombinant Factor VIII in a protein free medium |
| US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
| CN100427603C (zh) | 1999-10-04 | 2008-10-22 | 麦迪卡格公司 | 调控外源基因转录的方法 |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| JP5508661B2 (ja) * | 2003-02-12 | 2014-06-04 | シンセラ インコーポレイテッド | ランダムおよび非ランダムアルキレンオキシドポリマーアロイ組成物 |
| AU2003900887A0 (en) * | 2003-02-27 | 2003-03-13 | Novasel Australia Pty Ltd | Poloxamer emulsion preparations |
| US8802116B2 (en) * | 2003-02-27 | 2014-08-12 | Novasel Australia Pty. Ltd. | Poloxamer emulsion preparations |
| WO2005014162A1 (en) | 2003-08-04 | 2005-02-17 | Camurus Ab | Method for improving the properties of amphiphile particles |
| WO2005053652A1 (en) | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride |
| EP1809272A4 (en) | 2004-10-18 | 2008-01-02 | Maroon Biotech Corp | METHOD AND COMPOSITIONS FOR TREATING DAMAGES THROUGH FREE RADICALS |
| US9149433B2 (en) * | 2004-11-30 | 2015-10-06 | Basf Corporation | Method for formation of micro-prilled polymers |
| CN1939534B (zh) * | 2005-09-27 | 2010-12-01 | 长春金赛药业股份有限公司 | 含有人生长激素或人粒细胞巨噬细胞刺激因子的用于治疗损伤和溃疡的外用制剂 |
| RU2454220C2 (ru) * | 2006-08-16 | 2012-06-27 | Новартис Аг | Способ получения твердых дисперсий высококристаллических терапевтических соединений |
| KR100932613B1 (ko) | 2007-04-27 | 2009-12-17 | 한남대학교 산학협력단 | 고분자 용융공정을 이용한 약물전달용 생체적합성 고분자나노 미립구의 제조방법 및 그 나노 미립구 |
| WO2009055312A1 (en) * | 2007-10-22 | 2009-04-30 | Dfb Pharmaceuticals, Inc. | Process for producing a poloxamer gel |
| PL2235197T3 (pl) | 2007-12-27 | 2018-01-31 | Baxalta GmbH | Sposoby hodowli komórek |
| RU2612154C2 (ru) * | 2009-12-23 | 2017-03-02 | Санофи Пастер | Способ культивирования адгезионных клеток |
| JP6177873B2 (ja) * | 2012-03-30 | 2017-08-09 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | ミクロスフィア組成物、その調製方法及び用途 |
| BR112016021739B1 (pt) | 2014-03-25 | 2021-11-03 | Genentech, Inc | Método para preparar um poloxâmero para uso em um meio de cultura de célula |
-
2015
- 2015-03-25 BR BR112016021739-0A patent/BR112016021739B1/pt active IP Right Grant
- 2015-03-25 EP EP20151556.6A patent/EP3778702B1/en active Active
- 2015-03-25 CN CN201580026701.5A patent/CN106414552B/zh active Active
- 2015-03-25 CN CN202010723304.6A patent/CN111808276A/zh active Pending
- 2015-03-25 PL PL15715932T patent/PL3122799T3/pl unknown
- 2015-03-25 RU RU2016141568A patent/RU2710551C2/ru active
- 2015-03-25 JP JP2016558605A patent/JP6655548B2/ja active Active
- 2015-03-25 AU AU2015236008A patent/AU2015236008B2/en active Active
- 2015-03-25 HR HRP20200372TT patent/HRP20200372T1/hr unknown
- 2015-03-25 SG SG11201607929PA patent/SG11201607929PA/en unknown
- 2015-03-25 EP EP15715932.8A patent/EP3122799B8/en active Active
- 2015-03-25 MY MYPI2016001715A patent/MY178060A/en unknown
- 2015-03-25 CA CA2943357A patent/CA2943357C/en active Active
- 2015-03-25 ES ES15715932T patent/ES2778680T3/es active Active
- 2015-03-25 KR KR1020167029244A patent/KR102352250B1/ko active Active
- 2015-03-25 SI SI201531128T patent/SI3122799T1/sl unknown
- 2015-03-25 MX MX2016012288A patent/MX2016012288A/es unknown
- 2015-03-25 WO PCT/US2015/022592 patent/WO2015148736A1/en not_active Ceased
-
2016
- 2016-09-19 IL IL247902A patent/IL247902B/en active IP Right Grant
- 2016-09-22 US US15/273,155 patent/US11034793B2/en active Active
- 2016-09-22 MX MX2021001981A patent/MX2021001981A/es unknown
- 2016-09-28 ZA ZA2016/06711A patent/ZA201606711B/en unknown
-
2020
- 2020-02-04 JP JP2020017136A patent/JP2020103290A/ja not_active Withdrawn
- 2020-12-20 IL IL279583A patent/IL279583B/en unknown
-
2021
- 2021-05-13 US US17/319,886 patent/US11912823B2/en active Active
-
2022
- 2022-09-30 JP JP2022157928A patent/JP7472222B2/ja active Active
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