BR112016021739A2 - Método para preparar um poloxâmero para uso em um meio de cultura de célula - Google Patents

Método para preparar um poloxâmero para uso em um meio de cultura de célula

Info

Publication number
BR112016021739A2
BR112016021739A2 BR112016021739A BR112016021739A BR112016021739A2 BR 112016021739 A2 BR112016021739 A2 BR 112016021739A2 BR 112016021739 A BR112016021739 A BR 112016021739A BR 112016021739 A BR112016021739 A BR 112016021739A BR 112016021739 A2 BR112016021739 A2 BR 112016021739A2
Authority
BR
Brazil
Prior art keywords
cell culture
poloxamer
preparing
culture media
methods
Prior art date
Application number
BR112016021739A
Other languages
English (en)
Other versions
BR112016021739B1 (pt
Inventor
Prasadh Vissvesvaran Ganesh
David Kiss Robert
J Meier Steven
Kwon Inchan
Calhoun Kara
Winchester Kate
Adams Amelia
GLENN Marion
Koenig Stefan
DEESE Alan
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112016021739A2 publication Critical patent/BR112016021739A2/pt
Publication of BR112016021739B1 publication Critical patent/BR112016021739B1/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/30Post-polymerisation treatment, e.g. recovery, purification, drying
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C08G65/48Polymers modified by chemical after-treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/50Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing nitrogen, e.g. polyetheramines or Jeffamines(r)
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/58Ethylene oxide or propylene oxide copolymers, e.g. pluronics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/50Soluble polymers, e.g. polyethyleneglycol [PEG]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

MÉTODOS PARA PREPARAR UM POLOXÂMERO PARA USO EM MEIO DE CULTURA DE CÉLULA. A presente invenção proporciona métodos para preparar um poloxâmero para uso em um meio de cultura de célula. Também são fornecidos pela presente invenção meios de cultura de célula contendo o poloxâmero preparado pelos métodos deste documento, assim como métodos para usar os meios para cultura de células e produção de polipeptídeo de células.
BR112016021739-0A 2014-03-25 2015-03-25 Método para preparar um poloxâmero para uso em um meio de cultura de célula BR112016021739B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461970281P 2014-03-25 2014-03-25
US61/970,281 2014-03-25
PCT/US2015/022592 WO2015148736A1 (en) 2014-03-25 2015-03-25 Methods of preparing a poloxamer for use in cell culture medium

Publications (2)

Publication Number Publication Date
BR112016021739A2 true BR112016021739A2 (pt) 2017-08-15
BR112016021739B1 BR112016021739B1 (pt) 2021-11-03

Family

ID=52824596

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016021739-0A BR112016021739B1 (pt) 2014-03-25 2015-03-25 Método para preparar um poloxâmero para uso em um meio de cultura de célula

Country Status (19)

Country Link
US (2) US11034793B2 (pt)
EP (2) EP3122799B8 (pt)
JP (3) JP6655548B2 (pt)
KR (1) KR102352250B1 (pt)
CN (2) CN106414552B (pt)
AU (1) AU2015236008B2 (pt)
BR (1) BR112016021739B1 (pt)
CA (1) CA2943357C (pt)
ES (1) ES2778680T3 (pt)
HR (1) HRP20200372T1 (pt)
IL (2) IL247902B (pt)
MX (2) MX2016012288A (pt)
MY (1) MY178060A (pt)
PL (1) PL3122799T3 (pt)
RU (1) RU2710551C2 (pt)
SG (1) SG11201607929PA (pt)
SI (1) SI3122799T1 (pt)
WO (1) WO2015148736A1 (pt)
ZA (1) ZA201606711B (pt)

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EP3122799B8 (en) 2014-03-25 2020-03-11 F.Hoffmann-La Roche Ag Methods of preparing a poloxamer for use in cell culture medium
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EP3728471A1 (en) * 2017-12-21 2020-10-28 Sigma Aldrich Co. LLC Poloxamer compositions and methods of making and using same
RU2741710C1 (ru) * 2018-07-12 2021-01-28 Елена Валентиновна Аршинцева Термический способ стерилизации жидких лекарственных средств, содержащих в своем составе полоксамер
CA3107654A1 (en) * 2018-07-27 2020-01-30 Ajinomoto Co., Inc. Suspension culturing additive, suspension culturing medium and suspension culturing method for animal cells

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Also Published As

Publication number Publication date
IL247902A0 (en) 2016-11-30
KR20160138161A (ko) 2016-12-02
SG11201607929PA (en) 2016-10-28
WO2015148736A1 (en) 2015-10-01
IL279583B (en) 2022-03-01
IL247902B (en) 2021-01-31
BR112016021739B1 (pt) 2021-11-03
MX2021001981A (es) 2021-04-28
MX2016012288A (es) 2017-01-23
US20210371587A1 (en) 2021-12-02
CA2943357A1 (en) 2015-10-01
CN106414552A (zh) 2017-02-15
SI3122799T1 (sl) 2020-06-30
JP6655548B2 (ja) 2020-02-26
RU2016141568A3 (pt) 2018-09-26
JP2023011566A (ja) 2023-01-24
KR102352250B1 (ko) 2022-01-17
CN106414552B (zh) 2020-08-25
JP2017516459A (ja) 2017-06-22
EP3122799B8 (en) 2020-03-11
EP3122799A1 (en) 2017-02-01
IL279583A (en) 2021-03-01
WO2015148736A8 (en) 2016-08-18
US11034793B2 (en) 2021-06-15
JP7472222B2 (ja) 2024-04-22
AU2015236008B2 (en) 2018-12-20
NZ725151A (en) 2021-05-28
US11912823B2 (en) 2024-02-27
PL3122799T3 (pl) 2020-06-29
RU2016141568A (ru) 2018-04-28
HRP20200372T1 (hr) 2020-06-12
AU2015236008A1 (en) 2016-10-27
ZA201606711B (en) 2019-12-18
EP3778702A1 (en) 2021-02-17
EP3122799B1 (en) 2020-01-15
ES2778680T3 (es) 2020-08-11
CA2943357C (en) 2023-06-27
JP2020103290A (ja) 2020-07-09
US20170009015A1 (en) 2017-01-12
CN111808276A (zh) 2020-10-23
EP3778702B1 (en) 2023-06-28
MY178060A (en) 2020-09-30
RU2710551C2 (ru) 2019-12-27

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