BR112016021739A2 - Método para preparar um poloxâmero para uso em um meio de cultura de célula - Google Patents
Método para preparar um poloxâmero para uso em um meio de cultura de célulaInfo
- Publication number
- BR112016021739A2 BR112016021739A2 BR112016021739A BR112016021739A BR112016021739A2 BR 112016021739 A2 BR112016021739 A2 BR 112016021739A2 BR 112016021739 A BR112016021739 A BR 112016021739A BR 112016021739 A BR112016021739 A BR 112016021739A BR 112016021739 A2 BR112016021739 A2 BR 112016021739A2
- Authority
- BR
- Brazil
- Prior art keywords
- cell culture
- poloxamer
- preparing
- culture media
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 title abstract 4
- 239000006143 cell culture medium Substances 0.000 title abstract 4
- 229960000502 poloxamer Drugs 0.000 title abstract 4
- 229920001983 poloxamer Polymers 0.000 title abstract 4
- 238000004113 cell culture Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
- C08G65/48—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/50—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing nitrogen, e.g. polyetheramines or Jeffamines(r)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/58—Ethylene oxide or propylene oxide copolymers, e.g. pluronics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Polyesters Or Polycarbonates (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
MÉTODOS PARA PREPARAR UM POLOXÂMERO PARA USO EM MEIO DE CULTURA DE CÉLULA. A presente invenção proporciona métodos para preparar um poloxâmero para uso em um meio de cultura de célula. Também são fornecidos pela presente invenção meios de cultura de célula contendo o poloxâmero preparado pelos métodos deste documento, assim como métodos para usar os meios para cultura de células e produção de polipeptídeo de células.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461970281P | 2014-03-25 | 2014-03-25 | |
US61/970,281 | 2014-03-25 | ||
PCT/US2015/022592 WO2015148736A1 (en) | 2014-03-25 | 2015-03-25 | Methods of preparing a poloxamer for use in cell culture medium |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016021739A2 true BR112016021739A2 (pt) | 2017-08-15 |
BR112016021739B1 BR112016021739B1 (pt) | 2021-11-03 |
Family
ID=52824596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016021739-0A BR112016021739B1 (pt) | 2014-03-25 | 2015-03-25 | Método para preparar um poloxâmero para uso em um meio de cultura de célula |
Country Status (19)
Country | Link |
---|---|
US (2) | US11034793B2 (pt) |
EP (2) | EP3122799B8 (pt) |
JP (3) | JP6655548B2 (pt) |
KR (1) | KR102352250B1 (pt) |
CN (2) | CN106414552B (pt) |
AU (1) | AU2015236008B2 (pt) |
BR (1) | BR112016021739B1 (pt) |
CA (1) | CA2943357C (pt) |
ES (1) | ES2778680T3 (pt) |
HR (1) | HRP20200372T1 (pt) |
IL (2) | IL247902B (pt) |
MX (2) | MX2016012288A (pt) |
MY (1) | MY178060A (pt) |
PL (1) | PL3122799T3 (pt) |
RU (1) | RU2710551C2 (pt) |
SG (1) | SG11201607929PA (pt) |
SI (1) | SI3122799T1 (pt) |
WO (1) | WO2015148736A1 (pt) |
ZA (1) | ZA201606711B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3122799B8 (en) | 2014-03-25 | 2020-03-11 | F.Hoffmann-La Roche Ag | Methods of preparing a poloxamer for use in cell culture medium |
US11180610B2 (en) | 2016-03-17 | 2021-11-23 | Merck Patent Gmbh | Method for purifying poloxamers |
EP3728471A1 (en) * | 2017-12-21 | 2020-10-28 | Sigma Aldrich Co. LLC | Poloxamer compositions and methods of making and using same |
RU2741710C1 (ru) * | 2018-07-12 | 2021-01-28 | Елена Валентиновна Аршинцева | Термический способ стерилизации жидких лекарственных средств, содержащих в своем составе полоксамер |
CA3107654A1 (en) * | 2018-07-27 | 2020-01-30 | Ajinomoto Co., Inc. | Suspension culturing additive, suspension culturing medium and suspension culturing method for animal cells |
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ES2612530T3 (es) * | 2012-03-30 | 2017-05-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Composición de microesferas, método de preparación y aplicaciones de la misma |
EP3122799B8 (en) | 2014-03-25 | 2020-03-11 | F.Hoffmann-La Roche Ag | Methods of preparing a poloxamer for use in cell culture medium |
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2015
- 2015-03-25 EP EP15715932.8A patent/EP3122799B8/en active Active
- 2015-03-25 MX MX2016012288A patent/MX2016012288A/es unknown
- 2015-03-25 ES ES15715932T patent/ES2778680T3/es active Active
- 2015-03-25 BR BR112016021739-0A patent/BR112016021739B1/pt active IP Right Grant
- 2015-03-25 SG SG11201607929PA patent/SG11201607929PA/en unknown
- 2015-03-25 SI SI201531128T patent/SI3122799T1/sl unknown
- 2015-03-25 MY MYPI2016001715A patent/MY178060A/en unknown
- 2015-03-25 PL PL15715932T patent/PL3122799T3/pl unknown
- 2015-03-25 KR KR1020167029244A patent/KR102352250B1/ko active IP Right Grant
- 2015-03-25 AU AU2015236008A patent/AU2015236008B2/en active Active
- 2015-03-25 RU RU2016141568A patent/RU2710551C2/ru active
- 2015-03-25 WO PCT/US2015/022592 patent/WO2015148736A1/en active Application Filing
- 2015-03-25 EP EP20151556.6A patent/EP3778702B1/en active Active
- 2015-03-25 CN CN201580026701.5A patent/CN106414552B/zh active Active
- 2015-03-25 CA CA2943357A patent/CA2943357C/en active Active
- 2015-03-25 CN CN202010723304.6A patent/CN111808276A/zh active Pending
- 2015-03-25 JP JP2016558605A patent/JP6655548B2/ja active Active
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2016
- 2016-09-19 IL IL247902A patent/IL247902B/en active IP Right Grant
- 2016-09-22 US US15/273,155 patent/US11034793B2/en active Active
- 2016-09-22 MX MX2021001981A patent/MX2021001981A/es unknown
- 2016-09-28 ZA ZA2016/06711A patent/ZA201606711B/en unknown
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2020
- 2020-02-04 JP JP2020017136A patent/JP2020103290A/ja not_active Withdrawn
- 2020-03-04 HR HRP20200372TT patent/HRP20200372T1/hr unknown
- 2020-12-20 IL IL279583A patent/IL279583B/en unknown
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2021
- 2021-05-13 US US17/319,886 patent/US11912823B2/en active Active
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2022
- 2022-09-30 JP JP2022157928A patent/JP7472222B2/ja active Active
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/03/2015, OBSERVADAS AS CONDICOES LEGAIS. |