ES2179095T3 - Metodos y materiales anti bacterias gram positivas. - Google Patents

Metodos y materiales anti bacterias gram positivas.

Info

Publication number
ES2179095T3
ES2179095T3 ES95908545T ES95908545T ES2179095T3 ES 2179095 T3 ES2179095 T3 ES 2179095T3 ES 95908545 T ES95908545 T ES 95908545T ES 95908545 T ES95908545 T ES 95908545T ES 2179095 T3 ES2179095 T3 ES 2179095T3
Authority
ES
Spain
Prior art keywords
positive
gram
methods
materials
protein product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95908545T
Other languages
English (en)
Inventor
Arnold Horowitz
Lewis H Lambert Jr
Roger G Ii Little
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xoma Technology Ltd USA
Original Assignee
Xoma Technology Ltd USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/209,762 external-priority patent/US5733872A/en
Application filed by Xoma Technology Ltd USA filed Critical Xoma Technology Ltd USA
Application granted granted Critical
Publication of ES2179095T3 publication Critical patent/ES2179095T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4742—Bactericidal/Permeability-increasing protein [BPI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

SE HACE REFERENCIA A METODOS PARA TRATAR LAS INFECCIONES BACTERIANAS CAUSADAS POR BACTERIAS GRAM-POSITIVAS MEDIANTE LA ADMINISTRACION DE UN PRODUCTO PROTEINICO BPI SOLO, O EN COMBINACION CON UN ANTIBIOTICO. EL PRODUCTO PROTEINICO BPI SOLO TIENE UN EFECTO INHIBIDOR EN EL CRECIMIENTO O BACTERICIDA DE LOS ORGANISMOS GRAM-POSITIVOS SELECCIONADOS, ASIMISMO TIENE LA CAPACIDAD DE INCREMENTAR LA SUCEPTIBILIDAD DE LOS ORGANISMOS GRAM-POSITIVOS A LOS ANTIBIOTICOS PUDIENDO INCLUSO SUPERAR LA RESISTENCIA DE AQUELLOS ORGANISMOS AL ANTIBIOTICO.
ES95908545T 1994-01-14 1995-01-13 Metodos y materiales anti bacterias gram positivas. Expired - Lifetime ES2179095T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18322294A 1994-01-14 1994-01-14
US08/209,762 US5733872A (en) 1993-03-12 1994-03-11 Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
US27429994A 1994-07-11 1994-07-11
PCT/US1994/010427 WO1995019372A1 (en) 1994-01-14 1994-09-15 Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof

Publications (1)

Publication Number Publication Date
ES2179095T3 true ES2179095T3 (es) 2003-01-16

Family

ID=27391655

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95908545T Expired - Lifetime ES2179095T3 (es) 1994-01-14 1995-01-13 Metodos y materiales anti bacterias gram positivas.

Country Status (12)

Country Link
US (3) US5578572A (es)
EP (1) EP0754050B1 (es)
JP (1) JPH09508359A (es)
AT (1) ATE219684T1 (es)
AU (1) AU703192B2 (es)
CA (1) CA2181164C (es)
DE (1) DE69527195T2 (es)
DK (1) DK0754050T3 (es)
ES (1) ES2179095T3 (es)
HK (1) HK1014160A1 (es)
PT (1) PT754050E (es)
WO (1) WO1995019180A1 (es)

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DK0754050T3 (da) * 1994-01-14 2002-10-21 Xoma Technology Ltd Anti-gram-positive bakterielle fremgangsmåder og materialer
US5447913A (en) * 1994-03-11 1995-09-05 Xoma Corporation Therapeutic uses of bactericidal/permeability-increasing protein dimer products
US5912228A (en) * 1995-01-13 1999-06-15 Xoma Corporation Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
CA2227292A1 (en) * 1995-07-20 1997-02-06 Xoma Corporation Anti-fungal peptides
PT914144E (pt) * 1996-05-10 2001-05-31 Univ Texas Utilizacoes terapeuticas de produtos de proteinas bip contra a meningococcemia humana
US5741779A (en) 1996-05-10 1998-04-21 Xoma Corporation Antithrombotic materials and methods
DE69719754D1 (de) * 1996-05-23 2003-04-17 Xoma Technology Ltd Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung
US5888973A (en) * 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
US6180604B1 (en) * 1996-08-21 2001-01-30 Micrologix Biotech Inc. Compositions and methods for treating infections using analogues of indolicidin
US6503881B2 (en) 1996-08-21 2003-01-07 Micrologix Biotech Inc. Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
US6482796B2 (en) * 1996-11-01 2002-11-19 Xoma Corporation Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients
US6093573A (en) * 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US6013631A (en) 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
WO2000018798A1 (en) * 1998-09-25 2000-04-06 Xoma Technology Ltd. Antifungal and antibacterial peptide
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
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US6284517B1 (en) * 1999-05-28 2001-09-04 Lawrence Restaino Plating media for the presumptive identification of Bacillus cereus and Bacillus thuringiensis
EP1280772A2 (en) * 2000-04-26 2003-02-05 Wisconsin Alumni Research Foundation Triaryl cation antibiotics from environmental dna
US7527807B2 (en) * 2000-06-21 2009-05-05 Cubist Pharmaceuticals, Inc. Compositions and methods for increasing the oral absorption of antimicrobials
CA2430588A1 (en) * 2000-12-01 2002-07-18 Xoma Technology Ltd. Modulation of pericyte proliferation using bpi protein products or bpi inhibitors
PT1341769E (pt) 2000-12-15 2007-12-31 Vertex Pharma Inibidores de girase bacteriana e suas utilizações
US7214364B2 (en) 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
IL156596A0 (en) 2000-12-27 2004-01-04 Salus Pharma Inc Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections
US7138419B2 (en) * 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
US7490625B1 (en) 2001-04-23 2009-02-17 John Leslie Johnson Pilot valve manifold
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US20040037895A1 (en) * 2002-08-23 2004-02-26 Alex Zhu Methods of treating involuntary facial spasms and facial wrinkles
GB0230221D0 (en) * 2002-12-24 2003-02-05 South Tyneside Healthcare Antibiotic resistance testing
NZ561169A (en) * 2003-01-21 2008-06-30 Thallion Pharmaceuticals Inc Farnesyl dibenzodiazepinones, processes for their production and their use as pharmaceuticals
US7655646B2 (en) * 2003-01-21 2010-02-02 Thallion Pharmaceuticals, Inc. Dibenzodiazepinone analogues, processes for their production and their use as pharmaceuticals
US20050005101A1 (en) * 2003-07-03 2005-01-06 Yenduri Bhargava K. Kernel cryptographic module signature verification system and method
WO2005024025A1 (en) * 2003-09-11 2005-03-17 Ecopia Biosciences Inc. Polyene polyketides and methods of production
US7455840B2 (en) * 2003-11-19 2008-11-25 The Scripps Research Institute Compositions and methods to reduce mutagenesis
WO2007001332A2 (en) * 2004-08-04 2007-01-04 University Of Massachusetts Anti-pathogen immunoadhesins
WO2006047891A1 (en) * 2004-11-08 2006-05-11 Ecopia Biosciences Inc. Polycyclic aromatics and derivatives thereof and processes for their preparation
US20060286574A1 (en) * 2005-04-05 2006-12-21 The Scripps Research Institute & Achaogen, Inc. Compositions and methods for enhancing drug sensitivity and treating drug resistant infections and diseases
US20060241040A1 (en) * 2005-04-06 2006-10-26 Alberto Visintin Methods of treating disorders associated with toll-like receptor 4 (TLR4) signalling
AU2006242535B2 (en) * 2005-04-29 2012-08-09 Merck Sharp & Dohme Corp. Therapeutic compositions
US20080206276A1 (en) * 2005-07-08 2008-08-28 Michael Otto Targeting Poly-Gamma-Glutamic Acid to Treat Staphylococcus Epidermidis and Related Infections
EP1741440A1 (en) 2005-07-08 2007-01-10 Mellitus S.L. Use of BPI protein for the treatment of disorders of the metabolism and cardiovascular disorders
WO2009039004A1 (en) * 2007-09-20 2009-03-26 Dow Global Technologies Inc. A high throughput test method for evaluation of biocides against anaerobic microorganisms
US20100069827A1 (en) 2008-09-12 2010-03-18 Barry Neil Silberg Pre-Surgical Prophylactic Administration of Antibiotics and Therapeutic Agents
US9446227B2 (en) 2008-09-12 2016-09-20 Sonescence, Inc. Ultrasonic dispersion of compositions in tissue
EP2601194B1 (en) 2010-08-03 2016-05-25 Merck Sharp & Dohme Corp. Fused-imidazoyl compounds useful as antimicrobial agents
US8182842B1 (en) 2010-11-10 2012-05-22 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Physico-chemical-managed killing of penicillin-resistant static and growing gram-positive and gram-negative vegetative bacteria
AU2012205415B2 (en) 2011-01-14 2017-02-02 Spero Therapeutics, Inc. Pyrimidine gyrase and topoisomerase IV inhibitors
TWI554515B (zh) 2011-06-20 2016-10-21 維泰克斯製藥公司 旋轉酶（ｇｙｒａｓｅ）及拓樸異構酶抑制劑之磷酸酯
US9018216B2 (en) 2012-07-18 2015-04-28 Vertex Pharmaceuticals Incorporated Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
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CN106414552B (zh) 2014-03-25 2020-08-25 豪夫迈·罗氏有限公司 制备用于细胞培养基中的泊洛沙姆的方法
WO2015187968A1 (en) 2014-06-04 2015-12-10 Sonescence, Inc. Systems and methods for therapeutic agent delivery
WO2017075189A1 (en) 2015-10-27 2017-05-04 University Of Massachusetts Factor h-fc immunotherapy
RU2678447C2 (ru) * 2017-02-01 2019-01-29 Александр Николаевич Швыдков Способ исследования повышения антибиотикочувствительности условно-патогенной микрофлоры in vitro молочнокислой кормовой добавкой, содержащей культуру микроорганизмов streptococcus termophilus th-4
JP2019174077A (ja) * 2018-03-29 2019-10-10 ダイキン工業株式会社 薬剤入りカプセルおよび空気処理装置の部品

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US5198541A (en) * 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
EP0375724B1 (en) * 1987-08-11 1995-05-31 New York University Biologically active bactericidal/permeability-increasing protein fragments
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US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
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Also Published As

Publication number Publication date
WO1995019180A1 (en) 1995-07-20
DE69527195D1 (de) 2002-08-01
DE69527195T2 (de) 2003-03-06
AU1682295A (en) 1995-08-01
JPH09508359A (ja) 1997-08-26
CA2181164C (en) 2008-01-08
EP0754050B1 (en) 2002-06-26
PT754050E (pt) 2002-11-29
DK0754050T3 (da) 2002-10-21
US5783561A (en) 1998-07-21
EP0754050A1 (en) 1997-01-22
US6054431A (en) 2000-04-25
ATE219684T1 (de) 2002-07-15
US5578572A (en) 1996-11-26
HK1014160A1 (en) 1999-09-24
AU703192B2 (en) 1999-03-18
CA2181164A1 (en) 1995-07-20

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