ATE219684T1 - Anti gram positive bakterielle verfahren und mittel - Google Patents

Anti gram positive bakterielle verfahren und mittel

Info

Publication number
ATE219684T1
ATE219684T1 AT95908545T AT95908545T ATE219684T1 AT E219684 T1 ATE219684 T1 AT E219684T1 AT 95908545 T AT95908545 T AT 95908545T AT 95908545 T AT95908545 T AT 95908545T AT E219684 T1 ATE219684 T1 AT E219684T1
Authority
AT
Austria
Prior art keywords
gram
agent
positive bacterial
gram positive
protein product
Prior art date
Application number
AT95908545T
Other languages
English (en)
Inventor
Arnold Horowitz
Lewis H Lambert Jr
Roger G Ii Little
Original Assignee
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/209,762 external-priority patent/US5733872A/en
Application filed by Xoma Technology Ltd filed Critical Xoma Technology Ltd
Application granted granted Critical
Publication of ATE219684T1 publication Critical patent/ATE219684T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4742—Bactericidal/Permeability-increasing protein [BPI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT95908545T 1994-01-14 1995-01-13 Anti gram positive bakterielle verfahren und mittel ATE219684T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18322294A 1994-01-14 1994-01-14
US08/209,762 US5733872A (en) 1993-03-12 1994-03-11 Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
US27429994A 1994-07-11 1994-07-11
PCT/US1994/010427 WO1995019372A1 (en) 1994-01-14 1994-09-15 Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
PCT/US1995/000656 WO1995019180A1 (en) 1994-01-14 1995-01-13 Anti-gram-positive bacterial methods and materials

Publications (1)

Publication Number Publication Date
ATE219684T1 true ATE219684T1 (de) 2002-07-15

Family

ID=27391655

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95908545T ATE219684T1 (de) 1994-01-14 1995-01-13 Anti gram positive bakterielle verfahren und mittel

Country Status (11)

Country Link
US (3) US5578572A (de)
EP (1) EP0754050B1 (de)
JP (1) JPH09508359A (de)
AT (1) ATE219684T1 (de)
AU (1) AU703192B2 (de)
CA (1) CA2181164C (de)
DE (1) DE69527195T2 (de)
DK (1) DK0754050T3 (de)
ES (1) ES2179095T3 (de)
PT (1) PT754050E (de)
WO (1) WO1995019180A1 (de)

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US5652332A (en) * 1993-03-12 1997-07-29 Xoma Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
PT754050E (pt) * 1994-01-14 2002-11-29 Xoma Technology Ltd Metodos e materiais contra bacterias gram-positivas
US5447913A (en) 1994-03-11 1995-09-05 Xoma Corporation Therapeutic uses of bactericidal/permeability-increasing protein dimer products
US5912228A (en) * 1995-01-13 1999-06-15 Xoma Corporation Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
JP2000510845A (ja) * 1996-05-10 2000-08-22 ゾーマ コーポレイション ヒト髄膜炎菌血症のためのｂｐｉタンパク質産物の治療用途
US5741779A (en) 1996-05-10 1998-04-21 Xoma Corporation Antithrombotic materials and methods
JP2000511190A (ja) * 1996-05-23 2000-08-29 ゾーマ コーポレイション 外傷に起因する出血に見舞われたヒトにおけるｂｐｉタンパク質産物の治療用途
US5888973A (en) 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
US6503881B2 (en) * 1996-08-21 2003-01-07 Micrologix Biotech Inc. Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
US6180604B1 (en) 1996-08-21 2001-01-30 Micrologix Biotech Inc. Compositions and methods for treating infections using analogues of indolicidin
US6482796B2 (en) 1996-11-01 2002-11-19 Xoma Corporation Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients
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US6013631A (en) * 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
AU6163099A (en) * 1998-09-25 2000-04-17 Xoma Technology Ltd. Antifungal and antibacterial peptide
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US7056893B2 (en) * 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
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US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US20040037895A1 (en) * 2002-08-23 2004-02-26 Alex Zhu Methods of treating involuntary facial spasms and facial wrinkles
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US7655646B2 (en) * 2003-01-21 2010-02-02 Thallion Pharmaceuticals, Inc. Dibenzodiazepinone analogues, processes for their production and their use as pharmaceuticals
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US20050005101A1 (en) * 2003-07-03 2005-01-06 Yenduri Bhargava K. Kernel cryptographic module signature verification system and method
US7300921B2 (en) * 2003-09-11 2007-11-27 Ecopia Biosciences, Inc. Polyene polyketides and methods of production
US7455840B2 (en) * 2003-11-19 2008-11-25 The Scripps Research Institute Compositions and methods to reduce mutagenesis
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US20060106028A1 (en) * 2004-11-08 2006-05-18 Ecopia Biosciences, Inc. Polycyclic aromatics and derivatives thereof and processes for their preparation
US20060286574A1 (en) * 2005-04-05 2006-12-21 The Scripps Research Institute & Achaogen, Inc. Compositions and methods for enhancing drug sensitivity and treating drug resistant infections and diseases
US20060241040A1 (en) * 2005-04-06 2006-10-26 Alberto Visintin Methods of treating disorders associated with toll-like receptor 4 (TLR4) signalling
EP2974718A1 (de) * 2005-04-29 2016-01-20 Cubist Pharmaceuticals, Inc. Therapeutische zusammensetzungen
EP1741440A1 (de) 2005-07-08 2007-01-10 Mellitus S.L. Verwendung von BPI-proteine zur Behandlung von stoffwechselbedingten Erkrankungen und Herzkreislaufstörungen
WO2007008904A2 (en) 2005-07-08 2007-01-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Targeting poly-gamma-glutamic acid to treat staphylococcus epidermidis and related infections
EP2193369A1 (de) * 2007-09-20 2010-06-09 Dow Global Technologies Inc. Hochdurchsatz-testverfahren zur beurteilung von bioziden gegen anaerobe mikroorganismen
US9446227B2 (en) * 2008-09-12 2016-09-20 Sonescence, Inc. Ultrasonic dispersion of compositions in tissue
US20100069827A1 (en) 2008-09-12 2010-03-18 Barry Neil Silberg Pre-Surgical Prophylactic Administration of Antibiotics and Therapeutic Agents
EP2601194B1 (de) 2010-08-03 2016-05-25 Merck Sharp & Dohme Corp. Als antimikrobielle wirkstoffe geeignete fusionierte imidazoylverbindungen
US8182842B1 (en) 2010-11-10 2012-05-22 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Physico-chemical-managed killing of penicillin-resistant static and growing gram-positive and gram-negative vegetative bacteria
TWI546298B (zh) 2011-01-14 2016-08-21 維泰克斯製藥公司 旋轉酶及拓樸異構酶ｉｖ抑制劑
EP2721026B1 (de) 2011-06-20 2016-03-02 Vertex Pharmaceuticals Incorporated Phosphatester von gyrase und topoisomeraseinhibitoren
US9018216B2 (en) 2012-07-18 2015-04-28 Vertex Pharmaceuticals Incorporated Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
SG11201607929PA (en) 2014-03-25 2016-10-28 Genentech Inc Methods of preparing a poloxamer for use in cell culture medium
WO2015187968A1 (en) 2014-06-04 2015-12-10 Sonescence, Inc. Systems and methods for therapeutic agent delivery
WO2017075189A1 (en) 2015-10-27 2017-05-04 University Of Massachusetts Factor h-fc immunotherapy
RU2678447C2 (ru) * 2017-02-01 2019-01-29 Александр Николаевич Швыдков Способ исследования повышения антибиотикочувствительности условно-патогенной микрофлоры in vitro молочнокислой кормовой добавкой, содержащей культуру микроорганизмов streptococcus termophilus th-4
JP2019174077A (ja) * 2018-03-29 2019-10-10 ダイキン工業株式会社 薬剤入りカプセルおよび空気処理装置の部品

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Also Published As

Publication number Publication date
CA2181164A1 (en) 1995-07-20
US6054431A (en) 2000-04-25
JPH09508359A (ja) 1997-08-26
CA2181164C (en) 2008-01-08
PT754050E (pt) 2002-11-29
DE69527195D1 (de) 2002-08-01
US5578572A (en) 1996-11-26
DK0754050T3 (da) 2002-10-21
DE69527195T2 (de) 2003-03-06
HK1014160A1 (en) 1999-09-24
WO1995019180A1 (en) 1995-07-20
AU1682295A (en) 1995-08-01
US5783561A (en) 1998-07-21
EP0754050A1 (de) 1997-01-22
ES2179095T3 (es) 2003-01-16
EP0754050B1 (de) 2002-06-26
AU703192B2 (en) 1999-03-18

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee