MX2016012288A - Metodos para preparar un poloxamero para usar en medio de cultivo celular. - Google Patents

Metodos para preparar un poloxamero para usar en medio de cultivo celular.

Info

Publication number
MX2016012288A
MX2016012288A MX2016012288A MX2016012288A MX2016012288A MX 2016012288 A MX2016012288 A MX 2016012288A MX 2016012288 A MX2016012288 A MX 2016012288A MX 2016012288 A MX2016012288 A MX 2016012288A MX 2016012288 A MX2016012288 A MX 2016012288A
Authority
MX
Mexico
Prior art keywords
methods
poloxamer
cell culture
preparing
culture medium
Prior art date
Application number
MX2016012288A
Other languages
English (en)
Spanish (es)
Inventor
J Meier Steven
David Kiss Robert
Prasadh Vissvesvaran Ganesh
Kwon Inchan
Calhoun Kara
Adams Amelia
GLENN Marion
Koenig Stefan
DEESE Alan
Winchester Kate
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2016012288A publication Critical patent/MX2016012288A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C08G65/48—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/50—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing nitrogen, e.g. polyetheramines or Jeffamines(r)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/58—Ethylene oxide or propylene oxide copolymers, e.g. pluronics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
MX2016012288A 2014-03-25 2015-03-25 Metodos para preparar un poloxamero para usar en medio de cultivo celular. MX2016012288A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461970281P 2014-03-25 2014-03-25
PCT/US2015/022592 WO2015148736A1 (en) 2014-03-25 2015-03-25 Methods of preparing a poloxamer for use in cell culture medium

Publications (1)

Publication Number Publication Date
MX2016012288A true MX2016012288A (es) 2017-01-23

Family

ID=52824596

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016012288A MX2016012288A (es) 2014-03-25 2015-03-25 Metodos para preparar un poloxamero para usar en medio de cultivo celular.
MX2021001981A MX2021001981A (es) 2014-03-25 2016-09-22 Metodos para preparar un poloxamero para usar en medio de cultivo celular.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021001981A MX2021001981A (es) 2014-03-25 2016-09-22 Metodos para preparar un poloxamero para usar en medio de cultivo celular.

Country Status (19)

Country Link
US (2) US11034793B2 (https=)
EP (2) EP3778702B1 (https=)
JP (3) JP6655548B2 (https=)
KR (1) KR102352250B1 (https=)
CN (2) CN106414552B (https=)
AU (1) AU2015236008B2 (https=)
BR (1) BR112016021739B1 (https=)
CA (1) CA2943357C (https=)
ES (1) ES2778680T3 (https=)
HR (1) HRP20200372T1 (https=)
IL (2) IL247902B (https=)
MX (2) MX2016012288A (https=)
MY (1) MY178060A (https=)
PL (1) PL3122799T3 (https=)
RU (1) RU2710551C2 (https=)
SG (1) SG11201607929PA (https=)
SI (1) SI3122799T1 (https=)
WO (1) WO2015148736A1 (https=)
ZA (1) ZA201606711B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016021739B1 (pt) 2014-03-25 2021-11-03 Genentech, Inc Método para preparar um poloxâmero para uso em um meio de cultura de célula
EP3430072B1 (en) * 2016-03-17 2020-07-01 Merck Patent GmbH Method for purifying poloxamers
JP7135096B2 (ja) * 2017-12-21 2022-09-12 シグマ－アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニー ポロキサマー組成物ならびにその製造方法およびその使用
EP3790597A4 (en) * 2018-07-12 2022-03-09 Arshintseva, Elena Valentinovna THERMAL PROCESS FOR THE STERILIZATION OF POLOXAMER WITH LIQUID PHARMACEUTICALS
CN112469814A (zh) * 2018-07-27 2021-03-09 味之素株式会社 动物细胞的悬浮培养用添加物、悬浮培养用培养基和悬浮培养方法

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE266710C (https=)
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
AU632065B2 (en) 1988-09-23 1992-12-17 Novartis Vaccines And Diagnostics, Inc. Cell culture medium for enhanced cell growth, culture longevity and product expression
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
FR2646437B1 (fr) 1989-04-28 1991-08-30 Transgene Sa Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
EP1690934A3 (en) 1990-01-12 2008-07-30 Abgenix, Inc. Generation of xenogeneic antibodies
ATE300615T1 (de) 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
US5531925A (en) 1991-10-04 1996-07-02 Gs Biochem Ab Particles, method of preparing said particles and uses thereof
EP0754050B1 (en) 1994-01-14 2002-06-26 XOMA Technology Ltd. Anti gram positive bacterial methods and materials
US5912228A (en) * 1995-01-13 1999-06-15 Xoma Corporation Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
CA2219361C (en) 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0823941A4 (en) 1995-04-28 2001-09-19 Abgenix Inc HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
EP1500329B1 (en) 1996-12-03 2012-03-21 Amgen Fremont Inc. Human antibodies that specifically bind human TNF alpha
GB9625175D0 (en) * 1996-12-04 1997-01-22 Medi Cult As Serum-free cell culture media
US5804420A (en) 1997-04-18 1998-09-08 Bayer Corporation Preparation of recombinant Factor VIII in a protein free medium
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
CN100427603C (zh) 1999-10-04 2008-10-22 麦迪卡格公司 调控外源基因转录的方法
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
JP5508661B2 (ja) * 2003-02-12 2014-06-04 シンセラ インコーポレイテッド ランダムおよび非ランダムアルキレンオキシドポリマーアロイ組成物
AU2003900887A0 (en) * 2003-02-27 2003-03-13 Novasel Australia Pty Ltd Poloxamer emulsion preparations
US8802116B2 (en) * 2003-02-27 2014-08-12 Novasel Australia Pty. Ltd. Poloxamer emulsion preparations
WO2005014162A1 (en) 2003-08-04 2005-02-17 Camurus Ab Method for improving the properties of amphiphile particles
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
EP1809272A4 (en) 2004-10-18 2008-01-02 Maroon Biotech Corp METHOD AND COMPOSITIONS FOR TREATING DAMAGES THROUGH FREE RADICALS
US9149433B2 (en) * 2004-11-30 2015-10-06 Basf Corporation Method for formation of micro-prilled polymers
CN1939534B (zh) * 2005-09-27 2010-12-01 长春金赛药业股份有限公司 含有人生长激素或人粒细胞巨噬细胞刺激因子的用于治疗损伤和溃疡的外用制剂
RU2454220C2 (ru) * 2006-08-16 2012-06-27 Новартис Аг Способ получения твердых дисперсий высококристаллических терапевтических соединений
KR100932613B1 (ko) 2007-04-27 2009-12-17 한남대학교 산학협력단 고분자 용융공정을 이용한 약물전달용 생체적합성 고분자나노 미립구의 제조방법 및 그 나노 미립구
WO2009055312A1 (en) * 2007-10-22 2009-04-30 Dfb Pharmaceuticals, Inc. Process for producing a poloxamer gel
PL2235197T3 (pl) 2007-12-27 2018-01-31 Baxalta GmbH Sposoby hodowli komórek
RU2612154C2 (ru) * 2009-12-23 2017-03-02 Санофи Пастер Способ культивирования адгезионных клеток
JP6177873B2 (ja) * 2012-03-30 2017-08-09 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル ミクロスフィア組成物、その調製方法及び用途
BR112016021739B1 (pt) 2014-03-25 2021-11-03 Genentech, Inc Método para preparar um poloxâmero para uso em um meio de cultura de célula

Also Published As

Publication number Publication date
RU2710551C2 (ru) 2019-12-27
JP2023011566A (ja) 2023-01-24
BR112016021739A2 (pt) 2017-08-15
RU2016141568A (ru) 2018-04-28
US11912823B2 (en) 2024-02-27
KR20160138161A (ko) 2016-12-02
US11034793B2 (en) 2021-06-15
MX2021001981A (es) 2021-04-28
EP3122799B1 (en) 2020-01-15
JP2017516459A (ja) 2017-06-22
AU2015236008A1 (en) 2016-10-27
SI3122799T1 (sl) 2020-06-30
JP7472222B2 (ja) 2024-04-22
WO2015148736A8 (en) 2016-08-18
EP3778702B1 (en) 2023-06-28
CN106414552B (zh) 2020-08-25
SG11201607929PA (en) 2016-10-28
EP3122799B8 (en) 2020-03-11
PL3122799T3 (pl) 2020-06-29
RU2016141568A3 (https=) 2018-09-26
WO2015148736A1 (en) 2015-10-01
BR112016021739B1 (pt) 2021-11-03
CA2943357C (en) 2023-06-27
IL279583B (en) 2022-03-01
IL247902A0 (en) 2016-11-30
JP6655548B2 (ja) 2020-02-26
CA2943357A1 (en) 2015-10-01
ZA201606711B (en) 2019-12-18
MY178060A (en) 2020-09-30
EP3122799A1 (en) 2017-02-01
IL279583A (en) 2021-03-01
EP3778702A1 (en) 2021-02-17
IL247902B (en) 2021-01-31
ES2778680T3 (es) 2020-08-11
KR102352250B1 (ko) 2022-01-17
CN111808276A (zh) 2020-10-23
NZ725151A (en) 2021-05-28
US20210371587A1 (en) 2021-12-02
AU2015236008B2 (en) 2018-12-20
US20170009015A1 (en) 2017-01-12
CN106414552A (zh) 2017-02-15
HRP20200372T1 (hr) 2020-06-12
JP2020103290A (ja) 2020-07-09

Similar Documents

Publication Publication Date Title
MX2019003427A (es) Composiciones para cultivo celular y metodos para la produccion de polipeptidos.
SG10201809452RA (en) Cell culture compositions with antioxidants and methods for polypeptide production
MX2020009670A (es) Metodos de cultivo por perfusion y usos de los mismos.
EP3161127A4 (en) Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof
MX2021008142A (es) Metodos para cosechar cultivos de celulas de mamifero.
GB2548740A (en) Methods for generation of podocytes from pluripotent stem cells and cells produced by the same
TR201904270T4 (tr) Tanımlı koşullar altında insan pluripotent kök hücrelerinin hematoendotelyal farklılaşması için yöntemler ve materyaller.
EP3633029A4 (en) METHOD OF DEVELOPING A NATURAL KILLER CELL USING A T-CELL
EP3263697A4 (en) Culture medium for culturing mesenchymal stem cell, method for culturing mesenchymal stem cell, and mesenchymal stem cell
MX366112B (es) Medio de cultivo celular y metodos de produccion de anticuerpos.
EP3495467A4 (en) METHOD AND DEVICE FOR PRODUCING A CONTAINER, CELL CULTURE VESSEL, METHOD FOR CULTIVATING CELLS, METHOD FOR PRODUCING A CELL CULTURE VESSEL AND DEVICE FOR PRODUCING A CELL CULTURE VESSEL
EP3184627A4 (en) Culture medium for mesenchymal stem cells
HK1220404A1 (zh) 用於细胞培养的细胞外基质组合物珠粒
EP3124602A4 (en) Culture medium for pluripotent stem cells
MX2021007433A (es) Metodos de cultivo de una celula de mamifero.
MX2021001981A (es) Metodos para preparar un poloxamero para usar en medio de cultivo celular.
EA201791233A1 (ru) Материал стволовых клеток и способ его получения
EP3162892A4 (en) Method for culturing adhesive cells, culture vessel, and method for producing protein
EP3181686A4 (en) Culture medium and method for enriching and maintaining cancer stem cells (cscs) using said medium
EP3252146A4 (en) Medium composition for culturing stem cells
MX2022000516A (es) Metodos relacionados con celulas pluripotentes.
EP3144382A4 (en) Method for producing lactic acid bacteria medium, method for culturing lactic acid bacteria using same, and lactic acid bacteria powder using lactic acid bacteria obtained by said culture method
WO2015117033A3 (en) Methods of increasing protein production in mammalian cells
EP3194573A4 (en) Mammalian pluripotent stem cells, methods for their production, and uses thereof
MX2017008289A (es) Metodos para aumentar la estabilidad de la produccion de compuestos en celulas huesped microbianas.