HRP20200065T1 - Upotreba etilnog estera ikozapentaenske kiseline u liječenju hipertrigliceridemije - Google Patents

Upotreba etilnog estera ikozapentaenske kiseline u liječenju hipertrigliceridemije Download PDF

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Publication number
HRP20200065T1
HRP20200065T1 HRP20200065TT HRP20200065T HRP20200065T1 HR P20200065 T1 HRP20200065 T1 HR P20200065T1 HR P20200065T T HRP20200065T T HR P20200065TT HR P20200065 T HRP20200065 T HR P20200065T HR P20200065 T1 HRP20200065 T1 HR P20200065T1
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HR
Croatia
Prior art keywords
ethyl ester
acid ethyl
eicosapentaenoic acid
composition
acid
Prior art date
Application number
HRP20200065TT
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English (en)
Inventor
Mehar Manku
Ian Osterloh
Pierre Wicker
Rene Braeckman
Soni Paresh
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Amarin Pharmaceuticals Ireland Limited
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42102041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20200065(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amarin Pharmaceuticals Ireland Limited filed Critical Amarin Pharmaceuticals Ireland Limited
Publication of HRP20200065T1 publication Critical patent/HRP20200065T1/hr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (1)

1. Pripravak, naznačen time što je namijenjen upotrebi u liječenju umjerene do teške hipertrigliceridmije kod subjekta koji ima osnovnu razinu triglicerida u gladovanju od otprilike 500 mg/dl do otprilike 1500 mg/dl, gdje pripravak sadrži etilni ester ikozapentaenske kiseline, gdje etilni ester ikozapentaenske kiseline sadrži najmanje 96%, težinski, od svih masnih kiselina prisutnih u pripravku, gdje pripravak sadrži najviše 4% težinski, od ukupnih masnih kiselina koje nisu etilni ester ikozapentaenske kiseline, a pripravak sadrži otprilike 0,1% do otprilike 0,6% najmanje jedne masne kiseline koja nije etilni ester ikozapentaenske kiseline i dokozaheksaenska kiselina, i gdje se 4 kapsule, od kojih svaka sadrži 1 g pripravka, primjenjuju svakodnevno na subjektu.
HRP20200065TT 2009-02-10 2020-01-16 Upotreba etilnog estera ikozapentaenske kiseline u liječenju hipertrigliceridemije HRP20200065T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15129109P 2009-02-10 2009-02-10
US17375509P 2009-04-29 2009-04-29
EP13156122.7A EP2596786B1 (en) 2009-02-10 2010-02-09 Use of eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia

Publications (1)

Publication Number Publication Date
HRP20200065T1 true HRP20200065T1 (hr) 2020-04-03

Family

ID=42102041

Family Applications (3)

Application Number Title Priority Date Filing Date
HRP20130811AT HRP20130811T1 (en) 2009-02-10 2013-08-29 Use of eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia
HRP20200068TT HRP20200068T1 (hr) 2009-02-10 2020-01-16 Etilni ester ikozapentaenske kiseline, namijenjen liječenju hipertrigliceridemije
HRP20200065TT HRP20200065T1 (hr) 2009-02-10 2020-01-16 Upotreba etilnog estera ikozapentaenske kiseline u liječenju hipertrigliceridemije

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HRP20130811AT HRP20130811T1 (en) 2009-02-10 2013-08-29 Use of eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia
HRP20200068TT HRP20200068T1 (hr) 2009-02-10 2020-01-16 Etilni ester ikozapentaenske kiseline, namijenjen liječenju hipertrigliceridemije

Country Status (24)

Country Link
US (29) US8293727B2 (hr)
EP (5) EP2395991B1 (hr)
KR (2) KR101383006B1 (hr)
AU (1) AU2010213899B2 (hr)
BR (1) BRPI1007518A2 (hr)
CA (3) CA3089847C (hr)
CY (2) CY1122628T1 (hr)
DK (3) DK3037089T3 (hr)
ES (3) ES2768091T3 (hr)
HK (2) HK1165698A1 (hr)
HR (3) HRP20130811T1 (hr)
HU (1) HUE048299T2 (hr)
LT (2) LT2596786T (hr)
MX (1) MX2011008448A (hr)
NZ (1) NZ594395A (hr)
PH (1) PH12015500407B1 (hr)
PL (3) PL2395991T3 (hr)
PT (3) PT3037089T (hr)
RU (2) RU2505292C2 (hr)
SG (3) SG173612A1 (hr)
SI (3) SI3037089T1 (hr)
SM (1) SMT201300095B (hr)
WO (1) WO2010093634A1 (hr)
ZA (1) ZA201105612B (hr)

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