HRP20181869T1 - Metode i sustavi za pročišćavanje nekompleksiranog botulinskog neurotoksina - Google Patents

Metode i sustavi za pročišćavanje nekompleksiranog botulinskog neurotoksina

Info

Publication number
HRP20181869T1
HRP20181869T1 HRP20181869TT HRP20181869T HRP20181869T1 HR P20181869 T1 HRP20181869 T1 HR P20181869T1 HR P20181869T T HRP20181869T T HR P20181869TT HR P20181869 T HRP20181869 T HR P20181869T HR P20181869 T1 HRP20181869 T1 HR P20181869T1
Authority
HR
Croatia
Prior art keywords
uncomplexed
purification
systems
methods
botulinum neurotoxin
Prior art date
Application number
HRP20181869TT
Other languages
English (en)
Croatian (hr)
Inventor
Curtis L. Ruegg
Original Assignee
Revance Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43879799&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20181869(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Revance Therapeutics, Inc. filed Critical Revance Therapeutics, Inc.
Publication of HRP20181869T1 publication Critical patent/HRP20181869T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HRP20181869TT 2009-10-21 2010-10-20 Metode i sustavi za pročišćavanje nekompleksiranog botulinskog neurotoksina HRP20181869T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25381009P 2009-10-21 2009-10-21
EP10825598.5A EP2490986B2 (en) 2009-10-21 2010-10-20 Methods and systems for purifying non-complexed botulinum neurotoxin
PCT/US2010/053389 WO2011050072A1 (en) 2009-10-21 2010-10-20 Methods and systems for purifying non-complexed botulinum neurotoxin

Publications (1)

Publication Number Publication Date
HRP20181869T1 true HRP20181869T1 (hr) 2019-01-11

Family

ID=43879799

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20181869TT HRP20181869T1 (hr) 2009-10-21 2010-10-20 Metode i sustavi za pročišćavanje nekompleksiranog botulinskog neurotoksina

Country Status (24)

Country Link
US (5) US20120196349A1 (enExample)
EP (1) EP2490986B2 (enExample)
JP (1) JP5951490B2 (enExample)
KR (1) KR101819129B1 (enExample)
CN (2) CN104961812B (enExample)
AU (1) AU2010310749B2 (enExample)
BR (1) BR112012009227A2 (enExample)
CA (1) CA2773396C (enExample)
CO (1) CO6551670A2 (enExample)
CY (1) CY1120908T1 (enExample)
DK (1) DK2490986T4 (enExample)
ES (1) ES2688065T5 (enExample)
HR (1) HRP20181869T1 (enExample)
HU (1) HUE041599T2 (enExample)
IL (2) IL218532A (enExample)
LT (1) LT2490986T (enExample)
MX (3) MX2012004703A (enExample)
PH (1) PH12012500549A1 (enExample)
PL (1) PL2490986T3 (enExample)
PT (1) PT2490986T (enExample)
RS (1) RS58006B1 (enExample)
SI (1) SI2490986T1 (enExample)
SM (1) SMT201800487T1 (enExample)
WO (1) WO2011050072A1 (enExample)

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KR102463881B1 (ko) 2016-10-04 2022-11-07 (주)메디톡스 보툴리눔 독소 함유 용액으로부터 보툴리눔 독소를 분리하는 방법
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KR20230146049A (ko) * 2021-02-26 2023-10-18 충칭 클라루비스 파마슈티컬 컴퍼니 리미티드 폴리펩티드를 제조하기 위한 세포 용해 버퍼 분리 장비, 시스템 및 이의 용도
CN114958887B (zh) * 2021-02-26 2024-10-25 重庆誉颜制药有限公司 一种经修饰的毒素多肽的制备方法
KR102724650B1 (ko) * 2021-07-05 2024-11-01 주식회사 파마리서치바이오 클로스트리디움 보툴리눔 독소 복합체 단백질의 정제방법
KR102724651B1 (ko) * 2021-07-08 2024-11-01 주식회사 파마리서치바이오 비-독소 단백질이 제거된 클로스트리디움 보툴리눔 신경독소 단백질의 정제방법
KR102512757B1 (ko) * 2021-07-22 2023-03-22 (주)이니바이오 정제 수율이 향상된 보툴리눔 독소 복합체 정제방법
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Also Published As

Publication number Publication date
US20170029795A1 (en) 2017-02-02
US20110092682A1 (en) 2011-04-21
CO6551670A2 (es) 2012-10-31
DK2490986T3 (en) 2018-11-05
CA2773396C (en) 2020-12-15
PT2490986T (pt) 2018-11-13
PL2490986T3 (pl) 2019-03-29
IL218532A (en) 2016-10-31
EP2490986B2 (en) 2024-04-24
US20200277591A1 (en) 2020-09-03
CY1120908T1 (el) 2019-12-11
EP2490986A1 (en) 2012-08-29
HUE041599T2 (hu) 2019-05-28
IL248486A0 (en) 2016-12-29
US20150322419A1 (en) 2015-11-12
US20120196349A1 (en) 2012-08-02
PH12012500549A1 (en) 2017-08-23
LT2490986T (lt) 2018-11-26
RS58006B1 (sr) 2019-02-28
MX2019006519A (es) 2019-09-18
KR101819129B1 (ko) 2018-02-28
US11466262B2 (en) 2022-10-11
JP5951490B2 (ja) 2016-07-13
HK1215951A1 (zh) 2016-09-30
ES2688065T3 (es) 2018-10-30
KR20120099431A (ko) 2012-09-10
EP2490986A4 (en) 2013-11-13
JP2013508388A (ja) 2013-03-07
CN104961812A (zh) 2015-10-07
SI2490986T1 (sl) 2018-12-31
ES2688065T5 (es) 2024-10-04
SMT201800487T1 (it) 2019-01-11
AU2010310749A1 (en) 2012-03-29
CN102666396A (zh) 2012-09-12
BR112012009227A2 (pt) 2016-08-23
EP2490986B1 (en) 2018-08-08
HK1175453A1 (en) 2013-07-05
CN104961812B (zh) 2019-08-20
CN102666396B (zh) 2015-05-13
MX365496B (es) 2019-06-05
CA2773396A1 (en) 2011-04-28
IL218532A0 (en) 2012-07-31
MX2012004703A (es) 2012-06-08
WO2011050072A1 (en) 2011-04-28
US9469849B2 (en) 2016-10-18
AU2010310749B2 (en) 2016-02-11
DK2490986T4 (da) 2024-06-17

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