LT2490986T - Nekompleksinio botulino neurotoksino gryninimo būdai ir sistemos - Google Patents

Nekompleksinio botulino neurotoksino gryninimo būdai ir sistemos

Info

Publication number
LT2490986T
LT2490986T LTEP10825598.5T LT10825598T LT2490986T LT 2490986 T LT2490986 T LT 2490986T LT 10825598 T LT10825598 T LT 10825598T LT 2490986 T LT2490986 T LT 2490986T
Authority
LT
Lithuania
Prior art keywords
systems
methods
botulinum neurotoxin
purifying non
complexed botulinum
Prior art date
Application number
LTEP10825598.5T
Other languages
English (en)
Inventor
Curtis L. Ruegg
Original Assignee
Revance Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43879799&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2490986(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Revance Therapeutics, Inc. filed Critical Revance Therapeutics, Inc.
Publication of LT2490986T publication Critical patent/LT2490986T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24069Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTEP10825598.5T 2009-10-21 2010-10-20 Nekompleksinio botulino neurotoksino gryninimo būdai ir sistemos LT2490986T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25381009P 2009-10-21 2009-10-21
PCT/US2010/053389 WO2011050072A1 (en) 2009-10-21 2010-10-20 Methods and systems for purifying non-complexed botulinum neurotoxin

Publications (1)

Publication Number Publication Date
LT2490986T true LT2490986T (lt) 2018-11-26

Family

ID=43879799

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP10825598.5T LT2490986T (lt) 2009-10-21 2010-10-20 Nekompleksinio botulino neurotoksino gryninimo būdai ir sistemos

Country Status (24)

Country Link
US (5) US20110092682A1 (lt)
EP (1) EP2490986B2 (lt)
JP (1) JP5951490B2 (lt)
KR (1) KR101819129B1 (lt)
CN (2) CN102666396B (lt)
AU (1) AU2010310749B2 (lt)
BR (1) BR112012009227A2 (lt)
CA (1) CA2773396C (lt)
CO (1) CO6551670A2 (lt)
CY (1) CY1120908T1 (lt)
DK (1) DK2490986T4 (lt)
ES (1) ES2688065T5 (lt)
HR (1) HRP20181869T1 (lt)
HU (1) HUE041599T2 (lt)
IL (2) IL218532A (lt)
LT (1) LT2490986T (lt)
MX (3) MX2012004703A (lt)
PH (1) PH12012500549A1 (lt)
PL (1) PL2490986T3 (lt)
PT (1) PT2490986T (lt)
RS (1) RS58006B1 (lt)
SI (1) SI2490986T1 (lt)
SM (1) SMT201800487T1 (lt)
WO (1) WO2011050072A1 (lt)

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CN114958887B (zh) * 2021-02-26 2024-10-25 重庆誉颜制药有限公司 一种经修饰的毒素多肽的制备方法
KR102724650B1 (ko) * 2021-07-05 2024-11-01 주식회사 파마리서치바이오 클로스트리디움 보툴리눔 독소 복합체 단백질의 정제방법
KR102724651B1 (ko) * 2021-07-08 2024-11-01 주식회사 파마리서치바이오 비-독소 단백질이 제거된 클로스트리디움 보툴리눔 신경독소 단백질의 정제방법
KR102512757B1 (ko) * 2021-07-22 2023-03-22 (주)이니바이오 정제 수율이 향상된 보툴리눔 독소 복합체 정제방법
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Also Published As

Publication number Publication date
HRP20181869T1 (hr) 2019-01-11
WO2011050072A1 (en) 2011-04-28
HK1215951A1 (zh) 2016-09-30
SI2490986T1 (sl) 2018-12-31
DK2490986T3 (en) 2018-11-05
KR101819129B1 (ko) 2018-02-28
US20150322419A1 (en) 2015-11-12
EP2490986B1 (en) 2018-08-08
MX2019006519A (es) 2019-09-18
JP2013508388A (ja) 2013-03-07
CN102666396A (zh) 2012-09-12
CN102666396B (zh) 2015-05-13
IL218532A0 (en) 2012-07-31
CN104961812B (zh) 2019-08-20
US20200277591A1 (en) 2020-09-03
PT2490986T (pt) 2018-11-13
CA2773396C (en) 2020-12-15
RS58006B1 (sr) 2019-02-28
US20110092682A1 (en) 2011-04-21
PL2490986T3 (pl) 2019-03-29
AU2010310749A1 (en) 2012-03-29
DK2490986T4 (da) 2024-06-17
BR112012009227A2 (pt) 2016-08-23
AU2010310749B2 (en) 2016-02-11
US9469849B2 (en) 2016-10-18
HUE041599T2 (hu) 2019-05-28
IL218532A (en) 2016-10-31
CY1120908T1 (el) 2019-12-11
EP2490986B2 (en) 2024-04-24
KR20120099431A (ko) 2012-09-10
EP2490986A4 (en) 2013-11-13
EP2490986A1 (en) 2012-08-29
MX365496B (es) 2019-06-05
US20120196349A1 (en) 2012-08-02
CA2773396A1 (en) 2011-04-28
SMT201800487T1 (it) 2019-01-11
MX2012004703A (es) 2012-06-08
CN104961812A (zh) 2015-10-07
CO6551670A2 (es) 2012-10-31
US20170029795A1 (en) 2017-02-02
PH12012500549A1 (en) 2017-08-23
HK1175453A1 (en) 2013-07-05
JP5951490B2 (ja) 2016-07-13
ES2688065T5 (es) 2024-10-04
US11466262B2 (en) 2022-10-11
ES2688065T3 (es) 2018-10-30
IL248486A0 (en) 2016-12-29

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