HRP20161092T1 - Cdk inhibitori - Google Patents
Cdk inhibitori Download PDFInfo
- Publication number
- HRP20161092T1 HRP20161092T1 HRP20161092TT HRP20161092T HRP20161092T1 HR P20161092 T1 HRP20161092 T1 HR P20161092T1 HR P20161092T T HRP20161092T T HR P20161092TT HR P20161092 T HRP20161092 T HR P20161092T HR P20161092 T1 HRP20161092 T1 HR P20161092T1
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- Prior art keywords
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- formula
- compound according
- pharmaceutically acceptable
- acceptable salt
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/499—Spiro-condensed pyrazines or piperazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40649810P | 2010-10-25 | 2010-10-25 | |
| PCT/US2011/057749 WO2012061156A1 (en) | 2010-10-25 | 2011-10-25 | Cdk inhibitors |
| EP11838545.9A EP2632467B1 (en) | 2010-10-25 | 2011-10-25 | Cdk inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20161092T1 true HRP20161092T1 (hr) | 2016-10-21 |
Family
ID=46024778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20161092TT HRP20161092T1 (hr) | 2010-10-25 | 2011-10-25 | Cdk inhibitori |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8598197B2 (OSRAM) |
| EP (6) | EP3981770A1 (OSRAM) |
| JP (4) | JP5923509B2 (OSRAM) |
| KR (4) | KR102186969B1 (OSRAM) |
| CN (5) | CN103429243B (OSRAM) |
| AU (5) | AU2011323739B2 (OSRAM) |
| BR (1) | BR112013010018B1 (OSRAM) |
| CA (2) | CA2961937C (OSRAM) |
| CY (1) | CY1118004T1 (OSRAM) |
| DK (1) | DK2632467T3 (OSRAM) |
| ES (1) | ES2592515T3 (OSRAM) |
| HK (2) | HK1197067A1 (OSRAM) |
| HR (1) | HRP20161092T1 (OSRAM) |
| HU (1) | HUE030714T2 (OSRAM) |
| IL (5) | IL225940A0 (OSRAM) |
| LT (1) | LT2632467T (OSRAM) |
| MX (4) | MX367795B (OSRAM) |
| PL (1) | PL2632467T3 (OSRAM) |
| PT (1) | PT2632467T (OSRAM) |
| RS (1) | RS55135B1 (OSRAM) |
| RU (1) | RU2621674C2 (OSRAM) |
| SG (2) | SG10201508715YA (OSRAM) |
| SI (1) | SI2632467T1 (OSRAM) |
| SM (1) | SMT201600311B (OSRAM) |
| WO (1) | WO2012061156A1 (OSRAM) |
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| US8691830B2 (en) | 2010-10-25 | 2014-04-08 | G1 Therapeutics, Inc. | CDK inhibitors |
| CA2818046A1 (en) | 2010-11-17 | 2012-05-24 | The University Of North Carolina At Chapel Hill | Protection of renal tissues from ischemia through inhibition of the proliferative kinases cdk4 and cdk6 |
| WO2013148748A1 (en) | 2012-03-29 | 2013-10-03 | Francis Xavier Tavares | Lactam kinase inhibitors |
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