HRP20130691T1 - Prolyl hydroxylase inhibitors - Google Patents

Prolyl hydroxylase inhibitors

Info

Publication number
HRP20130691T1
HRP20130691T1 HRP20130691AT HRP20130691T HRP20130691T1 HR P20130691 T1 HRP20130691 T1 HR P20130691T1 HR P20130691A T HRP20130691A T HR P20130691AT HR P20130691 T HRP20130691 T HR P20130691T HR P20130691 T1 HRP20130691 T1 HR P20130691T1
Authority
HR
Croatia
Prior art keywords
prolyl hydroxylase
hydroxylase inhibitors
inhibitors
prolyl
hydroxylase
Prior art date
Application number
HRP20130691AT
Other languages
English (en)
Inventor
Joseph H. Gardner
Robert Shalwitz
Original Assignee
Aerpio Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aerpio Therapeutics Inc. filed Critical Aerpio Therapeutics Inc.
Publication of HRP20130691T1 publication Critical patent/HRP20130691T1/hr

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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    • C07—ORGANIC CHEMISTRY
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    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
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EP2496236A4 (en) 2012-09-12
JP5865411B2 (ja) 2016-02-17
ES2782999T3 (es) 2020-09-16
AU2010314973B2 (en) 2014-08-28
MX2012005274A (es) 2012-06-19
IL219610A (en) 2015-07-30
EP2649998B1 (en) 2015-03-04
EP2496082B1 (en) 2016-10-12
KR20120079846A (ko) 2012-07-13
JP2013508462A (ja) 2013-03-07
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HRP20150473T1 (hr) 2015-06-05
BR112012010762B1 (pt) 2021-08-03
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AU2010314976A1 (en) 2012-06-21
WO2011057112A1 (en) 2011-05-12
RU2521251C2 (ru) 2014-06-27
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JP5627040B2 (ja) 2014-11-19
IN2012DN04940A (hr) 2015-09-25
EP2496084B1 (en) 2015-06-10
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US8309537B2 (en) 2012-11-13
SI2496084T1 (sl) 2015-08-31
JP2013508464A (ja) 2013-03-07
HK1208806A1 (en) 2016-03-18
SMT201300096B (it) 2013-11-08
CN102595896A (zh) 2012-07-18
US20140364419A1 (en) 2014-12-11
PT2853265T (pt) 2017-11-07
AU2010314973B9 (en) 2015-03-19
CN102612367B (zh) 2014-02-19
EP3698794A1 (en) 2020-08-26
EP2952192A1 (en) 2015-12-09
CA2774043C (en) 2015-04-14
US9540326B2 (en) 2017-01-10
IL219611A (en) 2017-03-30
KR20150116464A (ko) 2015-10-15
EP2496236B1 (en) 2013-05-01
KR101591701B1 (ko) 2016-02-05
IL219612A0 (en) 2012-07-31
MX365138B (es) 2019-05-24
DK2496236T3 (da) 2013-07-08
ES2541613T3 (es) 2015-07-22
AU2010314976B2 (en) 2014-03-06
US20130158010A1 (en) 2013-06-20
BR112012010759B1 (pt) 2021-12-28
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JP2014159427A (ja) 2014-09-04
EP2496084A4 (en) 2012-11-21
JP2013508463A (ja) 2013-03-07
MX2012005273A (es) 2012-06-19
KR20150016414A (ko) 2015-02-11
ES2644998T3 (es) 2017-12-01
US20110110961A1 (en) 2011-05-12
KR20140095105A (ko) 2014-07-31
CA2774046A1 (en) 2011-05-12
BR112012010762A2 (pt) 2018-03-20
ZA201204104B (en) 2013-02-27
US20150218098A1 (en) 2015-08-06
CA2774043A1 (en) 2011-05-12
BR112012010759A2 (pt) 2015-10-06
IN2012DN04950A (hr) 2015-09-25
JP5961665B2 (ja) 2016-08-02
RS54010B1 (en) 2015-10-30
RU2012123387A (ru) 2013-12-20
US9278930B2 (en) 2016-03-08
KR101445946B1 (ko) 2014-09-29
HK1169313A1 (en) 2013-01-25
NZ629733A (en) 2016-02-26
CA2774039A1 (en) 2011-05-12
CN102595896B (zh) 2016-02-17
AU2010314982A1 (en) 2012-06-21
EP2853265B1 (en) 2017-07-26
US20190055198A1 (en) 2019-02-21
US20150157617A1 (en) 2015-06-11
DK2853265T3 (da) 2017-11-06
RU2012123386A (ru) 2013-12-20
PT2649998E (pt) 2015-04-21
JP2014221826A (ja) 2014-11-27
EP2496236A1 (en) 2012-09-12
IL219611A0 (en) 2012-07-31
RU2012123388A (ru) 2013-12-20
US9045495B2 (en) 2015-06-02
PL2496236T3 (pl) 2013-10-31
HK1190334A1 (en) 2014-07-04
CA2774046C (en) 2014-01-21
KR20120088833A (ko) 2012-08-08
MX2012005275A (es) 2012-06-19

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