HRP20110084T2 - Promotori mutantne aox1 - Google Patents
Promotori mutantne aox1 Download PDFInfo
- Publication number
- HRP20110084T2 HRP20110084T2 HR20110084T HRP20110084T HRP20110084T2 HR P20110084 T2 HRP20110084 T2 HR P20110084T2 HR 20110084 T HR20110084 T HR 20110084T HR P20110084 T HRP20110084 T HR P20110084T HR P20110084 T2 HRP20110084 T2 HR P20110084T2
- Authority
- HR
- Croatia
- Prior art keywords
- nucleotides
- nucleic acid
- cell
- promoter
- seq
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 claims abstract 49
- 125000003729 nucleotide group Chemical group 0.000 claims abstract 49
- 101710194180 Alcohol oxidase 1 Proteins 0.000 claims abstract 15
- 241000235058 Komagataella pastoris Species 0.000 claims abstract 9
- 102000040945 Transcription factor Human genes 0.000 claims abstract 8
- 108091023040 Transcription factor Proteins 0.000 claims abstract 8
- 230000035772 mutation Effects 0.000 claims abstract 6
- 210000004027 cell Anatomy 0.000 claims 25
- 150000007523 nucleic acids Chemical class 0.000 claims 22
- 102000039446 nucleic acids Human genes 0.000 claims 21
- 108020004707 nucleic acids Proteins 0.000 claims 21
- 241000235648 Pichia Species 0.000 claims 11
- 108090000623 proteins and genes Proteins 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 210000005253 yeast cell Anatomy 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 6
- 235000018102 proteins Nutrition 0.000 claims 6
- 239000003550 marker Substances 0.000 claims 5
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 101100523604 Mus musculus Rassf5 gene Proteins 0.000 claims 2
- 108010084455 Zeocin Proteins 0.000 claims 2
- 101150067149 abaA gene Proteins 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- BRZYSWJRSDMWLG-CAXSIQPQSA-N geneticin Chemical compound O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](C(C)O)O2)N)[C@@H](N)C[C@H]1N BRZYSWJRSDMWLG-CAXSIQPQSA-N 0.000 claims 2
- 238000002955 isolation Methods 0.000 claims 2
- CWCMIVBLVUHDHK-ZSNHEYEWSA-N phleomycin D1 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC[C@@H](N=1)C=1SC=C(N=1)C(=O)NCCCCNC(N)=N)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C CWCMIVBLVUHDHK-ZSNHEYEWSA-N 0.000 claims 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- -1 Stre Proteins 0.000 claims 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 101150038738 ble gene Proteins 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000004520 electroporation Methods 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 238000011534 incubation Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 235000010356 sorbitol Nutrition 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 230000009466 transformation Effects 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
- C12Y101/03013—Alcohol oxidase (1.1.3.13)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0030405A AT501955B1 (de) | 2005-02-23 | 2005-02-23 | Mutierte aox1-promotoren |
| PCT/AT2006/000079 WO2006089329A2 (en) | 2005-02-23 | 2006-02-23 | Mutant aox 1 promoters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20110084T1 HRP20110084T1 (en) | 2011-03-31 |
| HRP20110084T2 true HRP20110084T2 (hr) | 2011-10-31 |
Family
ID=36927772
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110084T HRP20110084T2 (hr) | 2005-02-23 | 2011-02-03 | Promotori mutantne aox1 |
| HR20110254T HRP20110254T1 (hr) | 2005-02-23 | 2011-04-08 | Promotori mutantne aox1 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110254T HRP20110254T1 (hr) | 2005-02-23 | 2011-04-08 | Promotori mutantne aox1 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US9012175B2 (de) |
| EP (2) | EP1851312B9 (de) |
| JP (2) | JP5497986B2 (de) |
| KR (2) | KR101358663B1 (de) |
| CN (2) | CN101128581B (de) |
| AT (3) | AT501955B1 (de) |
| AU (2) | AU2006216094B2 (de) |
| BR (1) | BRPI0606179B1 (de) |
| CA (2) | CA2785161C (de) |
| DE (2) | DE602006019789D1 (de) |
| DK (2) | DK2199389T3 (de) |
| ES (2) | ES2358086T3 (de) |
| HK (2) | HK1148313A1 (de) |
| HR (2) | HRP20110084T2 (de) |
| IN (1) | IN2012DN06694A (de) |
| NZ (2) | NZ585821A (de) |
| PL (2) | PL2199389T3 (de) |
| PT (1) | PT1851312E (de) |
| SI (2) | SI1851312T1 (de) |
| UA (2) | UA94399C2 (de) |
| WO (1) | WO2006089329A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7989206B2 (en) * | 2008-03-27 | 2011-08-02 | E.I. du Pont de Nemours and Company Alliance for Sustainable Energy LLC | High expression Zymomonas promoters |
| EP2300615A2 (de) * | 2008-07-11 | 2011-03-30 | Novozymes A/S | Das-promotervarianten aus pichia pastoris |
| EP2258855A1 (de) | 2009-05-28 | 2010-12-08 | Universität für Bodenkultur Wien | Expressionssequenzen |
| US20140011236A1 (en) * | 2011-03-22 | 2014-01-09 | Merch Sharp & Dohme Corp. | Promoters for high level recombinant expression in fungal host cells |
| GB201113419D0 (en) * | 2011-08-04 | 2011-09-21 | Fujifilm Diosynth Biotechnologies Uk Ltd | Yeast vector |
| EP2565262A1 (de) | 2011-08-31 | 2013-03-06 | VTU Holding GmbH | Protein-Expression |
| EP3508494B1 (de) * | 2011-10-07 | 2022-02-23 | Lonza Ltd | Regulierbarer promoter |
| WO2014088563A1 (en) * | 2012-12-05 | 2014-06-12 | Exxonmobil Research And Engineering Company | Nannochloropsis kozak consensus sequence |
| EP3839055B1 (de) * | 2013-03-08 | 2023-08-23 | Biogrammatics, Inc. | Hefepromotoren zur proteinexpression |
| DK3594351T3 (da) | 2013-03-08 | 2022-01-03 | Keck Graduate Inst Of Applied Life Sciences | Gærpromotorer fra pichia pastoris |
| ES2751336T3 (es) | 2013-03-15 | 2020-03-31 | Lonza Ag | Promotor constitutivo |
| US9150870B2 (en) | 2013-03-15 | 2015-10-06 | Lonza Ltd. | Constitutive promoter |
| US11518797B2 (en) | 2014-11-11 | 2022-12-06 | Clara Foods Co. | Methods and compositions for egg white protein production |
| JP6833812B2 (ja) | 2015-08-05 | 2021-02-24 | ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ | プロモーター変異体 |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
| AU2018291000B2 (en) * | 2017-06-30 | 2022-10-27 | Dow Global Technologies Llc | Coating for aldehyde remediation and method of making |
| EP3802832A1 (de) * | 2018-06-07 | 2021-04-14 | Basf Se | Promoter für hefe |
| JP2022501028A (ja) * | 2018-09-24 | 2022-01-06 | オルタ ドグ テクニク ユニヴェルシテシ | プロモータ工学によるアルコールデヒドロゲナーゼ２（ａｄｈ２）プロモータ変異体の設計 |
| WO2020068018A1 (en) * | 2018-09-24 | 2020-04-02 | Orta Dogu Teknik Universitesi | Modified aox1 promoter variants |
| CN110029120B (zh) * | 2019-03-19 | 2022-03-01 | 青岛蔚蓝生物集团有限公司 | 一种植酸酶高产菌株及其应用 |
| CN109735547B (zh) * | 2019-03-19 | 2022-05-31 | 青岛蔚蓝生物集团有限公司 | 一种提高毕赤酵母外源蛋白表达量的启动子及其应用 |
| CN110029122B (zh) * | 2019-03-19 | 2022-03-01 | 青岛蔚蓝生物集团有限公司 | 一种甘露聚糖酶高产菌株及其应用 |
| US11427932B2 (en) * | 2019-04-17 | 2022-08-30 | Impossible Foods Inc. | Materials and methods for protein production |
| CN110106168B (zh) * | 2019-05-27 | 2021-07-13 | 西南大学 | 基于转录因子间的互作关系构建双激素响应启动子的方法 |
| EP3997118A4 (de) | 2019-07-11 | 2023-07-19 | Clara Foods Co. | Proteinzusammensetzungen und verbrauchbare produkte daraus |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| CN110724720A (zh) * | 2019-11-01 | 2020-01-24 | 山东仙普爱瑞科技股份有限公司 | 一种猪α-干扰素的发酵工艺 |
| WO2022171827A1 (en) | 2021-02-12 | 2022-08-18 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Signal peptides for increased protein secretion |
| CA3131181C (en) * | 2021-06-24 | 2023-03-07 | BioBoost Synbio Consulting Inc. | Method for methanol free culturing of methylotrophic yeast for the biosynthesis of added value products |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2063890C (en) * | 1991-03-27 | 2007-03-13 | Masami Miura | Mutant aox2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism |
| CA2058820C (en) * | 1991-04-25 | 2003-07-15 | Kotikanyad Sreekrishna | Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells |
| JPH06209763A (ja) * | 1993-01-13 | 1994-08-02 | Green Cross Corp:The | 変異株 |
| WO1994021802A1 (en) * | 1993-03-25 | 1994-09-29 | Biosource Genetics Corporation | PICHIA PASTORIS ALCOHOL OXIDASE ZZA1 and $i(ZZA2) |
| JP3290108B2 (ja) * | 1997-08-29 | 2002-06-10 | 麒麟麦酒株式会社 | プロモーター活性を増大させるｄｎａ配列 |
| CN1192103C (zh) * | 1998-01-27 | 2005-03-09 | 三井化学株式会社 | 生产植酸酶的方法 |
| WO2000056903A2 (en) * | 1999-03-22 | 2000-09-28 | Zymogenetics, Inc. | IMPROVED METHODS FOR PRODUCING PROTEINS IN TRANSFORMED $i(PICHIA) |
| CN1188524C (zh) * | 2001-02-28 | 2005-02-09 | 珠江医院 | 人SP－A1在pichia pastoris中的表达 |
| CA2442935A1 (en) * | 2001-04-05 | 2002-10-17 | The Board Of Regents Of The University Of Nebraska | Alcohol oxidase 1 regulatory nucleotide sequences for heterologous gene expression in yeast |
| EP1431387B1 (de) * | 2002-12-20 | 2008-02-27 | Roche Diagnostics GmbH | Hitzelabile Desoxyribonuklease I-Varianten |
-
2005
- 2005-02-23 AT AT0030405A patent/AT501955B1/de not_active IP Right Cessation
-
2006
- 2006-02-23 EP EP06704721A patent/EP1851312B9/de active Active
- 2006-02-23 EP EP10155180A patent/EP2199389B1/de active Active
- 2006-02-23 CN CN2006800058881A patent/CN101128581B/zh active Active
- 2006-02-23 ES ES10155180T patent/ES2358086T3/es active Active
- 2006-02-23 WO PCT/AT2006/000079 patent/WO2006089329A2/en active Application Filing
- 2006-02-23 CA CA2785161A patent/CA2785161C/en active Active
- 2006-02-23 NZ NZ585821A patent/NZ585821A/en unknown
- 2006-02-23 KR KR1020127018581A patent/KR101358663B1/ko active IP Right Grant
- 2006-02-23 DE DE602006019789T patent/DE602006019789D1/de active Active
- 2006-02-23 AU AU2006216094A patent/AU2006216094B2/en active Active
- 2006-02-23 NZ NZ560542A patent/NZ560542A/en unknown
- 2006-02-23 DK DK10155180.2T patent/DK2199389T3/da active
- 2006-02-23 BR BRPI0606179-6A patent/BRPI0606179B1/pt active IP Right Grant
- 2006-02-23 KR KR1020077021821A patent/KR101352399B1/ko active IP Right Grant
- 2006-02-23 CA CA2598514A patent/CA2598514C/en active Active
- 2006-02-23 PL PL10155180T patent/PL2199389T3/pl unknown
- 2006-02-23 ES ES06704721T patent/ES2356127T3/es active Active
- 2006-02-23 SI SI200630919T patent/SI1851312T1/sl unknown
- 2006-02-23 UA UAA200710436A patent/UA94399C2/ru unknown
- 2006-02-23 PT PT06704721T patent/PT1851312E/pt unknown
- 2006-02-23 PL PL06704721T patent/PL1851312T3/pl unknown
- 2006-02-23 DK DK06704721.7T patent/DK1851312T5/da active
- 2006-02-23 JP JP2007556461A patent/JP5497986B2/ja active Active
- 2006-02-23 DE DE602006018113T patent/DE602006018113D1/de active Active
- 2006-02-23 US US11/817,005 patent/US9012175B2/en active Active
- 2006-02-23 SI SI200630962T patent/SI2199389T1/sl unknown
- 2006-02-23 UA UAA201012563A patent/UA98604C2/ru unknown
- 2006-02-23 AT AT06704721T patent/ATE487788T1/de active
- 2006-02-23 IN IN6694DEN2012 patent/IN2012DN06694A/en unknown
- 2006-02-23 CN CN2010101738787A patent/CN101935657B/zh active Active
- 2006-02-23 AT AT10155180T patent/ATE496125T1/de active
-
2008
- 2008-08-08 HK HK11102457.9A patent/HK1148313A1/xx not_active IP Right Cessation
- 2008-08-08 HK HK08108778.3A patent/HK1113172A1/xx not_active IP Right Cessation
-
2010
- 2010-04-14 US US12/759,763 patent/US9279129B2/en active Active
-
2011
- 2011-01-18 AU AU2011200187A patent/AU2011200187B2/en active Active
- 2011-02-03 HR HR20110084T patent/HRP20110084T2/hr unknown
- 2011-04-08 HR HR20110254T patent/HRP20110254T1/hr unknown
- 2011-11-09 JP JP2011245688A patent/JP5552107B2/ja active Active
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