HRP20100544T1 - Novi kristal 3-[5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzizoksazol-6-il)metoksi]fenil]propionske kiseline - Google Patents

Novi kristal 3-[5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzizoksazol-6-il)metoksi]fenil]propionske kiseline Download PDF

Info

Publication number
HRP20100544T1
HRP20100544T1 HR20100544T HRP20100544T HRP20100544T1 HR P20100544 T1 HRP20100544 T1 HR P20100544T1 HR 20100544 T HR20100544 T HR 20100544T HR P20100544 T HRP20100544 T HR P20100544T HR P20100544 T1 HRP20100544 T1 HR P20100544T1
Authority
HR
Croatia
Prior art keywords
benzisoxazol
hydroxybenzoyl
cyclopentyloxy
methoxy
hydroxy
Prior art date
Application number
HR20100544T
Other languages
English (en)
Inventor
Yonezawa Kenji
Kotsubo Hironori
Baba Yasutaka
Tada Yukie
Original Assignee
Toyama Chemical Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co. filed Critical Toyama Chemical Co.
Publication of HRP20100544T1 publication Critical patent/HRP20100544T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Kristal 3-{5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzisoksazol-6-il)metoksi]fenil}propionske kiseline, karakteriziran vršnim vrijednostima od 14.0, 16.0, 23.3, 23.7 i 26.3° na 2θ difrakcijskom kutu u uzorku rentgenske difrakcije u prahu. Patent sadrži još 1 patentni zahtjev.

Claims (2)

1. Kristal 3-{5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzisoksazol-6-il)metoksi]fenil}propionske kiseline, karakteriziran vršnim vrijednostima od 14.0, 16.0, 23.3, 23.7 i 26.3° na 2θ difrakcijskom kutu u uzorku rentgenske difrakcije u prahu.
2. Kristal 3-{5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzisoksazol-6-il)metoksi]fenil}propionske kiseline, karakteriziran vršnim vrijednostima od 14.6, 23.1, 24.7, 25.6 i 26.0 na 2θ difrakcijskom kutu u uzorku rentgenske difrakcije u prahu.
HR20100544T 2006-05-26 2010-10-05 Novi kristal 3-[5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzizoksazol-6-il)metoksi]fenil]propionske kiseline HRP20100544T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006146220 2006-05-26
PCT/JP2007/060670 WO2007138996A1 (ja) 2006-05-26 2007-05-25 ３－｛５－［４－（シクロペンチルオキシ）－２－ヒドロキシベンゾイル］－２－［（３－ヒドロキシ－１，２－ベンズイソオキサゾール－６－イル）メトキシ］フェニル｝プロピオン酸の新規な結晶

Publications (1)

Publication Number Publication Date
HRP20100544T1 true HRP20100544T1 (hr) 2010-11-30

Family

ID=38778516

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100544T HRP20100544T1 (hr) 2006-05-26 2010-10-05 Novi kristal 3-[5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzizoksazol-6-il)metoksi]fenil]propionske kiseline

Country Status (27)

Country Link
US (1) US7977492B2 (hr)
EP (1) EP2022788B1 (hr)
JP (1) JP5117381B2 (hr)
KR (1) KR101389038B1 (hr)
CN (1) CN101454298B (hr)
AT (1) ATE479666T1 (hr)
AU (1) AU2007268771B2 (hr)
BR (1) BRPI0712909A2 (hr)
CA (1) CA2652939C (hr)
CY (1) CY1111398T1 (hr)
DE (1) DE602007008882D1 (hr)
DK (1) DK2022788T3 (hr)
EC (1) ECSP089000A (hr)
ES (1) ES2351065T3 (hr)
HR (1) HRP20100544T1 (hr)
IL (1) IL195416A (hr)
MA (1) MA30510B1 (hr)
MX (1) MX2008014906A (hr)
NO (1) NO20084632L (hr)
NZ (1) NZ573034A (hr)
PL (1) PL2022788T3 (hr)
PT (1) PT2022788E (hr)
RS (1) RS51517B (hr)
RU (1) RU2429233C2 (hr)
SI (1) SI2022788T1 (hr)
WO (1) WO2007138996A1 (hr)
ZA (1) ZA200809922B (hr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ593062A (en) * 2006-02-21 2012-04-27 Toyama Chemical Co Ltd Process for production of 3-[5-[4-cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate for the process
DK2258361T3 (da) * 2008-03-27 2014-10-27 Toyama Chemical Co Ltd ANVENDELSE AF ET BENZOPHENONDERIVAT ELLER ET SALT DERAF I KOMBINATION MED EN TNFalfa-INHIBITOR OG FARMACEUTISK SAMMENSÆTNING INDEHOLDENDE DERIVATET ELLER SALTET DERAF OG INHIBITOREN
WO2009131098A1 (ja) 2008-04-22 2009-10-29 富山化学工業株式会社 ベンゾフェノン誘導体またはその塩および免疫抑制剤を組み合わせて使用する方法ならびにこれらを含有する医薬組成物
CN103183647B (zh) * 2011-12-28 2017-06-09 天津市国际生物医药联合研究院有限公司 3‑{[2‑[3‑氧‑(1,2‑苯并异噻唑‑6‑基)甲氧基‑5‑(2‑羟基‑4‑环戊氧基苯甲酰基)]苯基}丙酸的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042150A (en) 1960-01-26 1962-07-03 Lukawsky Michael Emergency brake and anti-skid device
AU7083894A (en) * 1993-07-06 1995-02-06 Yamanouchi Pharmaceutical Co., Ltd. Novel crystal of benzodiazepine derivative
EP1127869A4 (en) 1998-11-05 2007-05-02 Toyama Chemical Co Ltd NOVEL COMPOUNDS AND THEIR MEDICAL USE
JP4976617B2 (ja) 2000-03-17 2012-07-18 富山化学工業株式会社 新規なベンゾフェノン誘導体およびその塩
BR0214177A (pt) 2001-11-16 2004-09-14 Toyama Chemical Co Ltd Derivado de benzofenona, agente preventivo ou terapêutico para uma doença em que está envolvida expressão excessiva de ap-1, e, inibidor de ap-1

Also Published As

Publication number Publication date
KR20090014194A (ko) 2009-02-06
NO20084632L (no) 2008-12-12
CN101454298A (zh) 2009-06-10
WO2007138996A1 (ja) 2007-12-06
EP2022788B1 (en) 2010-09-01
ZA200809922B (en) 2010-02-24
ATE479666T1 (de) 2010-09-15
SI2022788T1 (sl) 2011-01-31
ECSP089000A (es) 2009-02-27
CA2652939A1 (en) 2007-12-06
JP5117381B2 (ja) 2013-01-16
PL2022788T3 (pl) 2011-03-31
RS51517B (en) 2011-06-30
MX2008014906A (es) 2008-12-09
MA30510B1 (fr) 2009-06-01
JPWO2007138996A1 (ja) 2009-10-08
RU2008151778A (ru) 2010-07-10
EP2022788A1 (en) 2009-02-11
US7977492B2 (en) 2011-07-12
RU2429233C2 (ru) 2011-09-20
CN101454298B (zh) 2011-11-16
AU2007268771B2 (en) 2011-12-01
EP2022788A4 (en) 2009-06-24
PT2022788E (pt) 2010-10-04
IL195416A (en) 2012-07-31
CA2652939C (en) 2014-12-02
CY1111398T1 (el) 2015-08-05
DK2022788T3 (da) 2010-12-13
KR101389038B1 (ko) 2014-04-28
NZ573034A (en) 2010-08-27
US20090275757A1 (en) 2009-11-05
BRPI0712909A2 (pt) 2012-10-02
AU2007268771A1 (en) 2007-12-06
IL195416A0 (en) 2009-08-03
ES2351065T3 (es) 2011-01-31
DE602007008882D1 (de) 2010-10-14

Similar Documents

Publication Publication Date Title
MX2010001773A (es) Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxasol .
ZA200802636B (en) Amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compounds as inhibitors of the beta-secretase (BACE)
NZ592603A (en) Aryl gpr120 receptor agonists and uses thereof
RS52112B (en) POLYMORPHIC FORMS 4- [3- (4-CYCLOPROPANECARBONYL-PIPERAZINE-1-CARBONYL) -4-FLUORO-BENZYL] -2H-FTALAZINE-1-ON
RS52900B (en) Benzoylpyrazole Compound, Process for Production and Production of Herbicides Containing Them
PL1981858T4 (pl) 3,5-di(arylo albo heteroarylo) izoksazole oraz 1,2,4-oksadiazole jako agoniści receptora S1P1, środki immunosupresyjne i przeciwzapalne
GB0428514D0 (en) Compounds
NZ581698A (en) Polycyclic indazole derivatives and their use as erk inhibitors for the treatment of cancer
TR201904655T4 (tr) Piridilaminoasetik asit bileşiği.
AR081226A1 (es) Polimorfo cristalino de 4-[5-[3-cloro-5-(trifluorometil)fenil]-4,5-dihidro-5-(trifluorometil)-3-isoxazolil]-n-[2-oxo-2-[(2,2,2-trifluoroetil)amino]etil]-1-naftalenocarboxamida
HRP20100544T1 (hr) Novi kristal 3-[5-[4-(ciklopentiloksi)-2-hidroksibenzoil]-2-[(3-hidroksi-1,2-benzizoksazol-6-il)metoksi]fenil]propionske kiseline
RS52795B (en) VINYL INDAZOLIL UNITS
RS52042B (en) FUNGICID MIXTURES
CY1111671T1 (el) Ετεροκυκλικη ενωση
NO20064288L (no) Tetraazabenzo(E)azulen-derivater og angaloger derav
NZ601786A (en) Novel compounds and compositions and methods of use
NO330968B1 (no) Ny fremgangsmate for syntesen av (1S)-4,5-dimetoksy-1-(metylaminometyl)-benzocyklobutan og addisjonssalter derav, og anvendelse i syntesen av ivabradin og addisjonssalter derav med en farmasoytisk akseptabel syre
AU2008229327A8 (en) Amino-5-[substituted-4-(difluoromethoxy)phenyl]-5- phenylimidazolone compounds as beta-secretase inhibitors
DK1874762T3 (da) Fremgangsmåde til fremstilling af 5-(4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamid
WO2007062308A3 (en) Homo- and heterocyclic compounds suitable as cetp inhibitors
EP2388000A3 (en) Neuroprotectant containing heterocyclic compound having specific structure
NO20084634L (no) Oral sammensetnig omfattende 3-(5-(4-(cyklopentyloksy)-2-hydroksybenzoyl)-2-((3-hydrolsy-1,2-benzisoksazol-6-yl) metoksy) fenyl) propionsyre eller salt derav
NO20075618L (no) Novel compounds as GLP-1 Agonists
BRPI0814989A2 (pt) Triazolilpiridina cetonas herbicidas.
BRPI0607085A2 (pt) derivados de oximas heterocìclicos, o respectivo processo de preparação e a respectiva utilização como agentes hipoglicemiantes e hipolipemiantes