RU2008151778A - Новые кристаллы 3-[5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил)метокси]фенил]пропиновой кислоты - Google Patents

Новые кристаллы 3-[5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил)метокси]фенил]пропиновой кислоты Download PDF

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Publication number
RU2008151778A
RU2008151778A RU2008151778/04A RU2008151778A RU2008151778A RU 2008151778 A RU2008151778 A RU 2008151778A RU 2008151778/04 A RU2008151778/04 A RU 2008151778/04A RU 2008151778 A RU2008151778 A RU 2008151778A RU 2008151778 A RU2008151778 A RU 2008151778A
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RU
Russia
Prior art keywords
hydroxybenzoyl
cyclopentyloxy
methoxy
hydroxy
phenyl
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RU2008151778/04A
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English (en)
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RU2429233C2 (ru
Inventor
Кендзи ЙОНЕЗАВА (JP)
Кендзи ЙОНЕЗАВА
Хиронори КОЦУБО (JP)
Хиронори КОЦУБО
Ясутака БАБА (JP)
Ясутака БАБА
Юкие ТАДА (JP)
Юкие ТАДА
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Тояма Кемикал Ко., Лтд. (Jp)
Тояма Кемикал Ко., Лтд.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1. Кристаллы 3-{5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил)метокси]фенил}пропионовой кислоты, характеризующиеся пиками в положениях 14,0, 16,0, 23,3, 23,7 и 26,3° по оси угла дифракции 2θ на порошковой рентгенограмме. ! 2. Кристаллы 3-{5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил)метокси]фенил}пропионовой кислоты, характеризующиеся пиками в положениях 14,6, 23,1, 24,7, 25,6 и 26,0° по оси угла дифракции 2θ на порошковой рентгенограмме.

Claims (2)

1. Кристаллы 3-{5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил)метокси]фенил}пропионовой кислоты, характеризующиеся пиками в положениях 14,0, 16,0, 23,3, 23,7 и 26,3° по оси угла дифракции 2θ на порошковой рентгенограмме.
2. Кристаллы 3-{5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил)метокси]фенил}пропионовой кислоты, характеризующиеся пиками в положениях 14,6, 23,1, 24,7, 25,6 и 26,0° по оси угла дифракции 2θ на порошковой рентгенограмме.
RU2008151778/04A 2006-05-26 2007-05-25 Новые кристаллы 3-[5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил) метокси]фенил]пропионовой кислоты RU2429233C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006-146220 2006-05-26
JP2006146220 2006-05-26

Publications (2)

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RU2008151778A true RU2008151778A (ru) 2010-07-10
RU2429233C2 RU2429233C2 (ru) 2011-09-20

Family

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RU2008151778/04A RU2429233C2 (ru) 2006-05-26 2007-05-25 Новые кристаллы 3-[5-[4-(циклопентилокси)-2-гидроксибензоил]-2-[(3-гидрокси-1,2-бензизоксазол-6-ил) метокси]фенил]пропионовой кислоты

Country Status (27)

Country Link
US (1) US7977492B2 (ru)
EP (1) EP2022788B1 (ru)
JP (1) JP5117381B2 (ru)
KR (1) KR101389038B1 (ru)
CN (1) CN101454298B (ru)
AT (1) ATE479666T1 (ru)
AU (1) AU2007268771B2 (ru)
BR (1) BRPI0712909A2 (ru)
CA (1) CA2652939C (ru)
CY (1) CY1111398T1 (ru)
DE (1) DE602007008882D1 (ru)
DK (1) DK2022788T3 (ru)
EC (1) ECSP089000A (ru)
ES (1) ES2351065T3 (ru)
HR (1) HRP20100544T1 (ru)
IL (1) IL195416A (ru)
MA (1) MA30510B1 (ru)
MX (1) MX2008014906A (ru)
NO (1) NO20084632L (ru)
NZ (1) NZ573034A (ru)
PL (1) PL2022788T3 (ru)
PT (1) PT2022788E (ru)
RS (1) RS51517B (ru)
RU (1) RU2429233C2 (ru)
SI (1) SI2022788T1 (ru)
WO (1) WO2007138996A1 (ru)
ZA (1) ZA200809922B (ru)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
PL2562170T3 (pl) * 2006-02-21 2015-03-31 Toyama Chemical Co Ltd Sposób wytwarzania estru kwasu 3-{5-[4-(cyklopentyloksy)- 2-hydroksybenzoilo]-2-[(3-okso-2-podstawionego-2,3-dihydro-1,2-benzizoksazol-6-ilo)metoksy]fenylo}- propionowego i związku pośredniego dla sposobu
NZ588128A (en) * 2008-03-27 2012-12-21 Toyama Chemical Co Ltd USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF alpha INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR
CN102014889A (zh) 2008-04-22 2011-04-13 富山化学工业株式会社 组合使用二苯甲酮衍生物或其盐和免疫抑制剂的方法以及包含这些组分的药物组合物
CN103183647B (zh) * 2011-12-28 2017-06-09 天津市国际生物医药联合研究院有限公司 3‑{[2‑[3‑氧‑(1,2‑苯并异噻唑‑6‑基)甲氧基‑5‑(2‑羟基‑4‑环戊氧基苯甲酰基)]苯基}丙酸的制备方法
CN118255728B (zh) * 2024-01-25 2024-07-30 中国医学科学院阜外医院 化合物的盐型晶型用于治疗射血分数保留的心衰的用途
CN118252824B (zh) * 2024-01-25 2024-09-17 中国医学科学院阜外医院 化合物用于治疗射血分数保留的心衰的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042150A (en) 1960-01-26 1962-07-03 Lukawsky Michael Emergency brake and anti-skid device
WO1995001964A1 (fr) * 1993-07-06 1995-01-19 Yamanouchi Pharmaceutical Co., Ltd. Nouveau cristal de derive de benzodiazepine
AU769778B2 (en) * 1998-11-05 2004-02-05 Toyama Chemical Co. Ltd. Novel compounds and pharmaceutical use thereof
JP4976617B2 (ja) * 2000-03-17 2012-07-18 富山化学工業株式会社 新規なベンゾフェノン誘導体およびその塩
JP4554926B2 (ja) 2001-11-16 2010-09-29 富山化学工業株式会社 新規なベンゾフェノン誘導体またはその塩

Also Published As

Publication number Publication date
BRPI0712909A2 (pt) 2012-10-02
KR101389038B1 (ko) 2014-04-28
DK2022788T3 (da) 2010-12-13
US7977492B2 (en) 2011-07-12
RS51517B (en) 2011-06-30
IL195416A (en) 2012-07-31
DE602007008882D1 (de) 2010-10-14
ES2351065T3 (es) 2011-01-31
MX2008014906A (es) 2008-12-09
ECSP089000A (es) 2009-02-27
KR20090014194A (ko) 2009-02-06
HRP20100544T1 (hr) 2010-11-30
AU2007268771B2 (en) 2011-12-01
ATE479666T1 (de) 2010-09-15
EP2022788A1 (en) 2009-02-11
SI2022788T1 (sl) 2011-01-31
RU2429233C2 (ru) 2011-09-20
EP2022788B1 (en) 2010-09-01
IL195416A0 (en) 2009-08-03
WO2007138996A1 (ja) 2007-12-06
PL2022788T3 (pl) 2011-03-31
CN101454298B (zh) 2011-11-16
CY1111398T1 (el) 2015-08-05
ZA200809922B (en) 2010-02-24
JPWO2007138996A1 (ja) 2009-10-08
EP2022788A4 (en) 2009-06-24
CA2652939C (en) 2014-12-02
AU2007268771A1 (en) 2007-12-06
US20090275757A1 (en) 2009-11-05
NO20084632L (no) 2008-12-12
JP5117381B2 (ja) 2013-01-16
CA2652939A1 (en) 2007-12-06
CN101454298A (zh) 2009-06-10
PT2022788E (pt) 2010-10-04
MA30510B1 (fr) 2009-06-01
NZ573034A (en) 2010-08-27

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Effective date: 20160526