DE602007008882D1 - Neuer kristall von 3-ä5-ä4-(cyclopentyloxy)-2-hydroxybenzoylü-2-ä(3-hydroxy-1,2-benzisoxazol-6-yl)methoxyüphenylüpropionsäure - Google Patents
Neuer kristall von 3-ä5-ä4-(cyclopentyloxy)-2-hydroxybenzoylü-2-ä(3-hydroxy-1,2-benzisoxazol-6-yl)methoxyüphenylüpropionsäureInfo
- Publication number
- DE602007008882D1 DE602007008882D1 DE602007008882T DE602007008882T DE602007008882D1 DE 602007008882 D1 DE602007008882 D1 DE 602007008882D1 DE 602007008882 T DE602007008882 T DE 602007008882T DE 602007008882 T DE602007008882 T DE 602007008882T DE 602007008882 D1 DE602007008882 D1 DE 602007008882D1
- Authority
- DE
- Germany
- Prior art keywords
- cyclopentyloxy
- hydroxy
- hydroxybenzoylü
- benzisoxazole
- new crystal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- RFSUYSZSJYUVMP-UHFFFAOYSA-N COC(CC1=CC2=C(C=C1)C(=O)NO2)(C3=CC=CC=C3)C(=O)O Chemical compound COC(CC1=CC2=C(C=C1)C(=O)NO2)(C3=CC=CC=C3)C(=O)O RFSUYSZSJYUVMP-UHFFFAOYSA-N 0.000 title 1
- -1 CYCLOPENTYLOXY Chemical class 0.000 title 1
- DALCQQSLNPLQFZ-UHFFFAOYSA-N 3-[5-(4-cyclopentyloxy-2-hydroxybenzoyl)-2-[(3-oxo-1,2-benzoxazol-6-yl)methoxy]phenyl]propanoic acid Chemical compound C=1C=C(OCC=2C=C3ON=C(O)C3=CC=2)C(CCC(=O)O)=CC=1C(=O)C(C(=C1)O)=CC=C1OC1CCCC1 DALCQQSLNPLQFZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 230000005611 electricity Effects 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006146220 | 2006-05-26 | ||
| PCT/JP2007/060670 WO2007138996A1 (ja) | 2006-05-26 | 2007-05-25 | ３－｛５－［４－（シクロペンチルオキシ）－２－ヒドロキシベンゾイル］－２－［（３－ヒドロキシ－１，２－ベンズイソオキサゾール－６－イル）メトキシ］フェニル｝プロピオン酸の新規な結晶 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602007008882D1 true DE602007008882D1 (de) | 2010-10-14 |
Family
ID=38778516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602007008882T Active DE602007008882D1 (de) | 2006-05-26 | 2007-05-25 | Neuer kristall von 3-ä5-ä4-(cyclopentyloxy)-2-hydroxybenzoylü-2-ä(3-hydroxy-1,2-benzisoxazol-6-yl)methoxyüphenylüpropionsäure |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7977492B2 (de) |
| EP (1) | EP2022788B1 (de) |
| JP (1) | JP5117381B2 (de) |
| KR (1) | KR101389038B1 (de) |
| CN (1) | CN101454298B (de) |
| AT (1) | ATE479666T1 (de) |
| AU (1) | AU2007268771B2 (de) |
| BR (1) | BRPI0712909A2 (de) |
| CA (1) | CA2652939C (de) |
| CY (1) | CY1111398T1 (de) |
| DE (1) | DE602007008882D1 (de) |
| DK (1) | DK2022788T3 (de) |
| EC (1) | ECSP089000A (de) |
| ES (1) | ES2351065T3 (de) |
| HR (1) | HRP20100544T1 (de) |
| IL (1) | IL195416A (de) |
| MA (1) | MA30510B1 (de) |
| MX (1) | MX2008014906A (de) |
| NO (1) | NO20084632L (de) |
| NZ (1) | NZ573034A (de) |
| PL (1) | PL2022788T3 (de) |
| PT (1) | PT2022788E (de) |
| RS (1) | RS51517B (de) |
| RU (1) | RU2429233C2 (de) |
| SI (1) | SI2022788T1 (de) |
| WO (1) | WO2007138996A1 (de) |
| ZA (1) | ZA200809922B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1988085E (pt) * | 2006-02-21 | 2015-02-05 | Toyama Chemical Co Ltd | Processo para a produção de éster de propionato de 3-[5-[4-(ciclopentiloxi)-2-hidroxibenzoil]-2-[(3- hidroxi-1,2-benzisoxazol-6-il)metoxi]fenilo] e produtos intermédios para o processo |
| PT2258361E (pt) * | 2008-03-27 | 2014-10-15 | Toyama Chemical Co Ltd | Utilização de uma combinação de um derivado de benzofenona ou de um seu sal com um inibidor de tnfalfa e composição farmacêutica contendo o referido sal ou derivado e o inibidor |
| KR101525851B1 (ko) | 2008-04-22 | 2015-06-04 | 토야마 케미칼 컴퍼니 리미티드 | 벤조페논 유도체 또는 그 염 및 면역억제제를 조합하여 사용하는 방법 및 이들을 함유하는 의약조성물 |
| CN103183647B (zh) * | 2011-12-28 | 2017-06-09 | 天津市国际生物医药联合研究院有限公司 | 3‑{[2‑[3‑氧‑(1,2‑苯并异噻唑‑6‑基)甲氧基‑5‑(2‑羟基‑4‑环戊氧基苯甲酰基)]苯基}丙酸的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3042150A (en) | 1960-01-26 | 1962-07-03 | Lukawsky Michael | Emergency brake and anti-skid device |
| US5637585A (en) * | 1993-07-06 | 1997-06-10 | Yamanouchi Pharmaceutical Co., Ltd. | Crystal form of benzodiazepine derivatives |
| CN100378063C (zh) * | 1998-11-05 | 2008-04-02 | 富山化学工业株式会社 | 新型化合物及其医药用途 |
| JP4976617B2 (ja) * | 2000-03-17 | 2012-07-18 | 富山化学工業株式会社 | 新規なベンゾフェノン誘導体およびその塩 |
| KR100947253B1 (ko) | 2001-11-16 | 2010-03-11 | 토야마 케미칼 컴퍼니 리미티드 | 신규의 벤조페논유도체 또는 그 염 |
-
2007
- 2007-05-25 PT PT07744104T patent/PT2022788E/pt unknown
- 2007-05-25 EP EP07744104A patent/EP2022788B1/de active Active
- 2007-05-25 NZ NZ573034A patent/NZ573034A/en not_active IP Right Cessation
- 2007-05-25 PL PL07744104T patent/PL2022788T3/pl unknown
- 2007-05-25 AU AU2007268771A patent/AU2007268771B2/en not_active Ceased
- 2007-05-25 JP JP2008517894A patent/JP5117381B2/ja not_active Expired - Fee Related
- 2007-05-25 DK DK07744104.6T patent/DK2022788T3/da active
- 2007-05-25 KR KR1020087029846A patent/KR101389038B1/ko not_active IP Right Cessation
- 2007-05-25 US US12/302,375 patent/US7977492B2/en not_active Expired - Fee Related
- 2007-05-25 RU RU2008151778/04A patent/RU2429233C2/ru not_active IP Right Cessation
- 2007-05-25 CA CA2652939A patent/CA2652939C/en not_active Expired - Fee Related
- 2007-05-25 RS RSP-2010/0522A patent/RS51517B/en unknown
- 2007-05-25 BR BRPI0712909-2A patent/BRPI0712909A2/pt not_active IP Right Cessation
- 2007-05-25 ES ES07744104T patent/ES2351065T3/es active Active
- 2007-05-25 AT AT07744104T patent/ATE479666T1/de active
- 2007-05-25 SI SI200730416T patent/SI2022788T1/sl unknown
- 2007-05-25 MX MX2008014906A patent/MX2008014906A/es active IP Right Grant
- 2007-05-25 WO PCT/JP2007/060670 patent/WO2007138996A1/ja active Application Filing
- 2007-05-25 DE DE602007008882T patent/DE602007008882D1/de active Active
- 2007-05-25 CN CN2007800193483A patent/CN101454298B/zh not_active Expired - Fee Related
-
2008
- 2008-11-04 NO NO20084632A patent/NO20084632L/no unknown
- 2008-11-20 ZA ZA2008/09922A patent/ZA200809922B/en unknown
- 2008-11-20 IL IL195416A patent/IL195416A/en not_active IP Right Cessation
- 2008-12-12 MA MA31468A patent/MA30510B1/fr unknown
- 2008-12-23 EC EC2008009000A patent/ECSP089000A/es unknown
-
2010
- 2010-10-05 HR HR20100544T patent/HRP20100544T1/hr unknown
- 2010-12-01 CY CY20101101102T patent/CY1111398T1/el unknown
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