NO20084632L - Nye krystaller av 3-[5-[4-(cyclopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]-fenyl]propion syre - Google Patents
Nye krystaller av 3-[5-[4-(cyclopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]-fenyl]propion syreInfo
- Publication number
- NO20084632L NO20084632L NO20084632A NO20084632A NO20084632L NO 20084632 L NO20084632 L NO 20084632L NO 20084632 A NO20084632 A NO 20084632A NO 20084632 A NO20084632 A NO 20084632A NO 20084632 L NO20084632 L NO 20084632L
- Authority
- NO
- Norway
- Prior art keywords
- hydroxybenzoyl
- cyclopentyloxy
- hydroxy
- propionic acid
- benzisoxazol
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 3
- DALCQQSLNPLQFZ-UHFFFAOYSA-N 3-[5-(4-cyclopentyloxy-2-hydroxybenzoyl)-2-[(3-oxo-1,2-benzoxazol-6-yl)methoxy]phenyl]propanoic acid Chemical compound C=1C=C(OCC=2C=C3ON=C(O)C3=CC=2)C(CCC(=O)O)=CC=1C(=O)C(C(=C1)O)=CC=C1OC1CCCC1 DALCQQSLNPLQFZ-UHFFFAOYSA-N 0.000 title abstract 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 abstract 2
- QLDQYRDCPNBPII-UHFFFAOYSA-N 1,2-benzoxazol-3-one Chemical compound C1=CC=C2C(O)=NOC2=C1 QLDQYRDCPNBPII-UHFFFAOYSA-N 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 125000001887 cyclopentyloxy group Chemical group C1(CCCC1)O* 0.000 abstract 1
- 230000005611 electricity Effects 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
- 235000019260 propionic acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Krystallen av 3-{5-[4-(cyklopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]fenyl}propionsyre som har topper i posisjonene 14,0, 16,0, 23,3, 23,7 og 26,3° og krystallen av 3-{5-[4-(cyklopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]fenyl}propionsyre som har topper i posisjonene 14,6, 23,1, 24,7, 25,6 og 26,0° ved diffraksjonsvinkel 2? i et pulver røntgendiffraksjonsmønster, har et lite, spesifikt volum, lar seg vanskelig lade med elektrisitet, er lett håndterbare og er anvendelige som en aktiv farmasøytisk bestanddel i utmerkede antirevmatiske midler.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006146220 | 2006-05-26 | ||
PCT/JP2007/060670 WO2007138996A1 (ja) | 2006-05-26 | 2007-05-25 | 3-{5-[4-(シクロペンチルオキシ)-2-ヒドロキシベンゾイル]-2-[(3-ヒドロキシ-1,2-ベンズイソオキサゾール-6-イル)メトキシ]フェニル}プロピオン酸の新規な結晶 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20084632L true NO20084632L (no) | 2008-12-12 |
Family
ID=38778516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084632A NO20084632L (no) | 2006-05-26 | 2008-11-04 | Nye krystaller av 3-[5-[4-(cyclopentyloksy)-2-hydroksybenzoyl]-2-[(3-hydroksy-1,2-benzisoksazol-6-yl)metoksy]-fenyl]propion syre |
Country Status (27)
Country | Link |
---|---|
US (1) | US7977492B2 (no) |
EP (1) | EP2022788B1 (no) |
JP (1) | JP5117381B2 (no) |
KR (1) | KR101389038B1 (no) |
CN (1) | CN101454298B (no) |
AT (1) | ATE479666T1 (no) |
AU (1) | AU2007268771B2 (no) |
BR (1) | BRPI0712909A2 (no) |
CA (1) | CA2652939C (no) |
CY (1) | CY1111398T1 (no) |
DE (1) | DE602007008882D1 (no) |
DK (1) | DK2022788T3 (no) |
EC (1) | ECSP089000A (no) |
ES (1) | ES2351065T3 (no) |
HR (1) | HRP20100544T1 (no) |
IL (1) | IL195416A (no) |
MA (1) | MA30510B1 (no) |
MX (1) | MX2008014906A (no) |
NO (1) | NO20084632L (no) |
NZ (1) | NZ573034A (no) |
PL (1) | PL2022788T3 (no) |
PT (1) | PT2022788E (no) |
RS (1) | RS51517B (no) |
RU (1) | RU2429233C2 (no) |
SI (1) | SI2022788T1 (no) |
WO (1) | WO2007138996A1 (no) |
ZA (1) | ZA200809922B (no) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0707989A2 (pt) * | 2006-02-21 | 2011-05-17 | Toyama Chemical Co Ltd | métodos para preparar um derivado de ácido fenilpropiÈnico, um derivado de benzofenona, um derivado de 6-metil-1, 2-benzisoxazol-3(2h) -ona e ácido 2-oxo-2h-cromeno carboxìlico, derivado de 6-(halometil) -1, 2-benzisoxazol-3(2h) -ona, e, derivado de benzofenona ou um sal do mesmo |
CA2719290A1 (en) * | 2008-03-27 | 2009-10-01 | Toyama Chemical Co., Ltd. | Use of benzophenone derivative or salt thereof and tnf.alpha. inhibitor in combination and pharmaceutical composition containing the derivative or salt thereof and the inhibitor |
MX2010011666A (es) | 2008-04-22 | 2010-12-06 | Toyama Chemical Co Ltd | Metodo para usar una combinacion de derivado de benzofenona o sal del mismo y un agente inmunosupresor, y una composicion farmaceutica que consta de estos compuestos. |
CN103183647B (zh) * | 2011-12-28 | 2017-06-09 | 天津市国际生物医药联合研究院有限公司 | 3‑{[2‑[3‑氧‑(1,2‑苯并异噻唑‑6‑基)甲氧基‑5‑(2‑羟基‑4‑环戊氧基苯甲酰基)]苯基}丙酸的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3042150A (en) | 1960-01-26 | 1962-07-03 | Lukawsky Michael | Emergency brake and anti-skid device |
US5637585A (en) * | 1993-07-06 | 1997-06-10 | Yamanouchi Pharmaceutical Co., Ltd. | Crystal form of benzodiazepine derivatives |
KR100702686B1 (ko) * | 1998-11-05 | 2007-04-04 | 토야마 케미칼 컴퍼니 리미티드 | 신규화합물 및 그 의약용도 |
JP4976617B2 (ja) * | 2000-03-17 | 2012-07-18 | 富山化学工業株式会社 | 新規なベンゾフェノン誘導体およびその塩 |
ES2394963T3 (es) * | 2001-11-16 | 2013-02-07 | Toyama Chemical Co., Ltd. | Nuevos derivados de benzofenona o sales de los mismos |
-
2007
- 2007-05-25 CA CA2652939A patent/CA2652939C/en not_active Expired - Fee Related
- 2007-05-25 AU AU2007268771A patent/AU2007268771B2/en not_active Ceased
- 2007-05-25 NZ NZ573034A patent/NZ573034A/en not_active IP Right Cessation
- 2007-05-25 CN CN2007800193483A patent/CN101454298B/zh not_active Expired - Fee Related
- 2007-05-25 KR KR1020087029846A patent/KR101389038B1/ko not_active IP Right Cessation
- 2007-05-25 DE DE602007008882T patent/DE602007008882D1/de active Active
- 2007-05-25 DK DK07744104.6T patent/DK2022788T3/da active
- 2007-05-25 PT PT07744104T patent/PT2022788E/pt unknown
- 2007-05-25 EP EP07744104A patent/EP2022788B1/en active Active
- 2007-05-25 AT AT07744104T patent/ATE479666T1/de active
- 2007-05-25 SI SI200730416T patent/SI2022788T1/sl unknown
- 2007-05-25 JP JP2008517894A patent/JP5117381B2/ja not_active Expired - Fee Related
- 2007-05-25 RS RSP-2010/0522A patent/RS51517B/en unknown
- 2007-05-25 ES ES07744104T patent/ES2351065T3/es active Active
- 2007-05-25 RU RU2008151778/04A patent/RU2429233C2/ru not_active IP Right Cessation
- 2007-05-25 WO PCT/JP2007/060670 patent/WO2007138996A1/ja active Application Filing
- 2007-05-25 US US12/302,375 patent/US7977492B2/en not_active Expired - Fee Related
- 2007-05-25 MX MX2008014906A patent/MX2008014906A/es active IP Right Grant
- 2007-05-25 BR BRPI0712909-2A patent/BRPI0712909A2/pt not_active IP Right Cessation
- 2007-05-25 PL PL07744104T patent/PL2022788T3/pl unknown
-
2008
- 2008-11-04 NO NO20084632A patent/NO20084632L/no unknown
- 2008-11-20 ZA ZA2008/09922A patent/ZA200809922B/en unknown
- 2008-11-20 IL IL195416A patent/IL195416A/en not_active IP Right Cessation
- 2008-12-12 MA MA31468A patent/MA30510B1/fr unknown
- 2008-12-23 EC EC2008009000A patent/ECSP089000A/es unknown
-
2010
- 2010-10-05 HR HR20100544T patent/HRP20100544T1/hr unknown
- 2010-12-01 CY CY20101101102T patent/CY1111398T1/el unknown
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