HRP20100153T1 - Antagonisti kemokin receptora - Google Patents

Antagonisti kemokin receptora Download PDF

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Publication number
HRP20100153T1
HRP20100153T1 HR20100153T HRP20100153T HRP20100153T1 HR P20100153 T1 HRP20100153 T1 HR P20100153T1 HR 20100153 T HR20100153 T HR 20100153T HR P20100153 T HRP20100153 T HR P20100153T HR P20100153 T1 HRP20100153 T1 HR P20100153T1
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HR
Croatia
Prior art keywords
piperidin
indole
amide
carboxylic acid
ethyl
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Application number
HR20100153T
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English (en)
Croatian (hr)
Inventor
Hersperger Ren�
Janser Philipp
Pfenninger Emil
Juerg Wuethrich Hans
Miltz Wolfgang
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Novartis Ag
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32011733&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20100153(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HRP20100153T1 publication Critical patent/HRP20100153T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
  • Virology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
HR20100153T 2004-02-11 2010-03-17 Antagonisti kemokin receptora HRP20100153T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0403038.3A GB0403038D0 (en) 2004-02-11 2004-02-11 Organic compounds
PCT/EP2005/001362 WO2005077932A2 (fr) 2004-02-11 2005-02-10 Antagonistes du recepteur de la chimiokine

Publications (1)

Publication Number Publication Date
HRP20100153T1 true HRP20100153T1 (hr) 2010-06-30

Family

ID=32011733

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100153T HRP20100153T1 (hr) 2004-02-11 2010-03-17 Antagonisti kemokin receptora

Country Status (34)

Country Link
US (2) US7858781B2 (fr)
EP (1) EP1720859B1 (fr)
JP (1) JP4550072B2 (fr)
KR (1) KR100883236B1 (fr)
CN (2) CN1946713A (fr)
AR (1) AR047545A1 (fr)
AT (1) ATE452886T1 (fr)
AU (1) AU2005212510B2 (fr)
BR (1) BRPI0507617A (fr)
CA (1) CA2554642C (fr)
CY (1) CY1109936T1 (fr)
DE (1) DE602005018456D1 (fr)
DK (1) DK1720859T3 (fr)
EC (1) ECSP066753A (fr)
ES (1) ES2338898T3 (fr)
GB (1) GB0403038D0 (fr)
HK (1) HK1098464A1 (fr)
HR (1) HRP20100153T1 (fr)
IL (1) IL177183A (fr)
MA (1) MA28432B1 (fr)
MY (1) MY142444A (fr)
NO (1) NO20064077L (fr)
NZ (1) NZ548741A (fr)
PE (1) PE20051169A1 (fr)
PL (1) PL1720859T3 (fr)
PT (1) PT1720859E (fr)
RS (1) RS51203B (fr)
RU (1) RU2395506C2 (fr)
SG (1) SG164288A1 (fr)
SI (1) SI1720859T1 (fr)
TN (1) TNSN06255A1 (fr)
TW (1) TWI346553B (fr)
WO (1) WO2005077932A2 (fr)
ZA (1) ZA200606180B (fr)

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AR065369A1 (es) * 2007-02-19 2009-06-03 Novartis Ag Derivados de ciclohexil - amida del acido aril- carboxilico
US20100035862A1 (en) * 2008-06-25 2010-02-11 Abbott Laboratories Novel aza-cyclic indole-2-carboxamides and methods of use thereof
US8273900B2 (en) * 2008-08-07 2012-09-25 Novartis Ag Organic compounds
SI2513115T1 (sl) 2009-12-18 2014-02-28 Basilea Pharmaceutica Ag Triciklični antibiotiki
ES2594409T3 (es) 2011-02-23 2016-12-20 Lupin Limited Derivados de heteroarilo como moduladores del nAChR á7
US20140005174A1 (en) * 2011-03-17 2014-01-02 Anilkumar G. Nair Indole derivatives useful as ccr2 antagonists
ES2596369T3 (es) 2011-06-17 2017-01-09 Basilea Pharmaceutica Ag Antibióticos N-heterotricíclicos
US8846656B2 (en) 2011-07-22 2014-09-30 Novartis Ag Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as C5a receptor modulators
CN102952062B (zh) * 2011-08-12 2016-06-08 中国医学科学院医药生物技术研究所 取代苯并杂环类化合物及其制备方法和应用
LT2797416T (lt) 2011-12-28 2017-10-25 Global Blood Therapeutics, Inc. Pakeistieji benzaldehido junginiai ir jų panaudojimo būdai, didinant audinių aprūpinimą deguonimi
ES2790358T3 (es) 2011-12-28 2020-10-27 Global Blood Therapeutics Inc Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
IN2014MN01756A (fr) 2012-03-06 2015-07-03 Lupin Ltd
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
KR20150132146A (ko) 2013-03-15 2015-11-25 글로벌 블러드 테라퓨틱스, 인크. 헤모글로빈 조정을 위한 화합물 및 이의 용도
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
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