HRP20070132T3 - Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones - Google Patents
Hydroxyalkyl substituted pyrido-7-pyrimidin-7-onesInfo
- Publication number
- HRP20070132T3 HRP20070132T3 HR20070132T HRP20070132T HRP20070132T3 HR P20070132 T3 HRP20070132 T3 HR P20070132T3 HR 20070132 T HR20070132 T HR 20070132T HR P20070132 T HRP20070132 T HR P20070132T HR P20070132 T3 HRP20070132 T3 HR P20070132T3
- Authority
- HR
- Croatia
- Prior art keywords
- pyrimidin
- ones
- hydroxyalkyl substituted
- substituted pyrido
- hydroxyalkyl
- Prior art date
Links
- 125000002768 hydroxyalkyl group Chemical group 0.000 title abstract 3
- 125000005350 hydroxycycloalkyl group Chemical group 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000005188 oxoalkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51978903P | 2003-11-13 | 2003-11-13 | |
| PCT/EP2004/012475 WO2005047284A1 (en) | 2003-11-13 | 2004-11-04 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20070132T3 true HRP20070132T3 (en) | 2007-05-31 |
Family
ID=34590444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20070132T HRP20070132T3 (en) | 2003-11-13 | 2007-03-30 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US7348331B2 (da) |
| EP (1) | EP1685131B1 (da) |
| JP (1) | JP4616839B2 (da) |
| KR (1) | KR100816321B1 (da) |
| CN (1) | CN100455582C (da) |
| AR (1) | AR046705A1 (da) |
| AT (1) | ATE356124T1 (da) |
| AU (1) | AU2004289428B2 (da) |
| BR (1) | BRPI0416030A (da) |
| CA (1) | CA2544247A1 (da) |
| CO (1) | CO5690600A2 (da) |
| DE (1) | DE602004005238T2 (da) |
| DK (1) | DK1685131T3 (da) |
| ES (1) | ES2281843T3 (da) |
| HK (1) | HK1099021A1 (da) |
| HR (1) | HRP20070132T3 (da) |
| IL (1) | IL175284A0 (da) |
| MY (1) | MY141011A (da) |
| NO (1) | NO20062256L (da) |
| NZ (1) | NZ546634A (da) |
| PL (1) | PL1685131T3 (da) |
| PT (1) | PT1685131E (da) |
| RU (1) | RU2348632C2 (da) |
| SI (1) | SI1685131T1 (da) |
| TW (1) | TWI349670B (da) |
| WO (1) | WO2005047284A1 (da) |
| ZA (1) | ZA200603829B (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7935709B2 (en) | 2006-07-17 | 2011-05-03 | Amgen Inc. | 2-quinazolinone compounds and methods of use |
| EP2097370A2 (en) * | 2006-12-22 | 2009-09-09 | F. Hoffmann-Roche AG | Compounds and methods for amino-alkylenediol synthesis |
| CA2690327A1 (en) * | 2007-06-15 | 2008-12-18 | Thomas P. Cleary | A novel process for the preparation of 3-amino-pentan-1,5-diol |
| US8889696B2 (en) * | 2009-12-18 | 2014-11-18 | Temple University—Of the Commonwealth System of Higher Education | Substituted pyrido[2,3-d]pyrimidin-7(8H)-ones and therapeutic uses thereof |
| DK3102577T3 (da) * | 2014-02-07 | 2018-11-12 | Principia Biopharma Inc | Quinolonderivater som fibroblast-vækstfaktorreceptorinhibitorer |
| JP6940480B2 (ja) | 2015-08-11 | 2021-09-29 | プリンシピア バイオファーマ インコーポレイテッド | Ｆｇｆｒ阻害剤の合成方法 |
| CN105418609B (zh) * | 2015-12-31 | 2017-06-23 | 山东大学 | 4‑(1,2,3‑三氮唑取代苯胺基)‑吡啶骈嘧啶酮衍生物及其制备方法与应用 |
| US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
| AU2017274442B2 (en) | 2016-06-02 | 2021-08-19 | Abbvie Inc. | Glucocorticoid receptor agonist and immunoconjugates thereof |
| HUE053648T2 (hu) | 2016-06-08 | 2021-07-28 | Support Venture Gmbh | Gyógyászati kombinációk rák kezelésére |
| EP3500258A1 (en) | 2016-08-17 | 2019-06-26 | Support-Venture GmbH | Method of preventing or treating hearing loss |
| SG10202110804WA (en) | 2017-04-04 | 2021-11-29 | Kinarus Ag | Methods of preventing or treating ophthalmic diseases |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| PT3691620T (pt) | 2017-10-05 | 2022-10-06 | Fulcrum Therapeutics Inc | Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd |
| EP3884962A1 (en) | 2017-12-01 | 2021-09-29 | AbbVie Inc. | Glucocorticoid receptor agonist and immunoconjugates thereof |
| EP3797107B1 (en) | 2018-05-21 | 2022-08-10 | Nerviano Medical Sciences S.r.l. | Heterocondensed pyridone compounds and their use as idh inhibitors |
| MA53114A (fr) | 2018-07-13 | 2021-05-19 | Kinarus Ag | Combinaisons d'agonistes de ppar et d'inhibiteurs de kinase p38 pour prévenir ou traiter des maladies fibrotiques |
| US20230000871A1 (en) | 2019-11-08 | 2023-01-05 | Nerviano Medical Sciences S.R.L. | Gem-disubstituted heterocyclic compounds and their use as idh inhibitors |
| US20230263803A1 (en) | 2020-08-11 | 2023-08-24 | Kinarus Ag | Methods of preventing or treating covid-19 and related viral diseases or disorders |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215216A (en) | 1979-04-18 | 1980-07-29 | American Home Products Corporation | 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives |
| US5037826A (en) | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
| AU598093B2 (en) | 1987-02-07 | 1990-06-14 | Wellcome Foundation Limited, The | Pyridopyrimidines, methods for their preparation and pharmaceutical formulations thereof |
| WO1993017682A1 (en) | 1992-03-04 | 1993-09-16 | Abbott Laboratories | Angiotensin ii receptor antagonists |
| IL115256A0 (en) | 1994-11-14 | 1995-12-31 | Warner Lambert Co | 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use |
| ES2146782T3 (es) | 1994-11-14 | 2000-08-16 | Warner Lambert Co | 6-aril-pirido(2,3-d)pirimidinas y naftiridinas para la inhibicion de la proliferacion celular inducida por la proteina tirosina quinasa. |
| IL117923A (en) | 1995-05-03 | 2000-06-01 | Warner Lambert Co | Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds |
| US5620981A (en) | 1995-05-03 | 1997-04-15 | Warner-Lambert Company | Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation |
| ATE391719T1 (de) | 1997-02-05 | 2008-04-15 | Warner Lambert Co | Pyrido (2,3-d) pyrimidine und 4-amino-primidine als inhibitoren der zellulären proliferation |
| US5945422A (en) | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| AU763839B2 (en) | 1998-05-26 | 2003-07-31 | Warner-Lambert Company | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
| US7053070B2 (en) | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| BR0017075A (pt) | 2000-01-27 | 2002-11-05 | Warner Lambert Co | Derivados de piridopirimidinona para tratamento de doença neurodegenerativa |
| WO2001070741A1 (en) | 2000-03-06 | 2001-09-27 | Warner-Lambert Company | 5-alkylpyrido[2,3-d]pyrimidines tyrosine kinase inhibitors |
| US6518276B2 (en) | 2000-08-31 | 2003-02-11 | Syntex (U.S.A.) Llc | 7-oxo-pyridopyrimidines (II) |
| CA2420286A1 (en) * | 2000-08-31 | 2002-03-07 | F. Hoffmann-La Roche Ag | 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation |
| IL156872A0 (en) * | 2001-02-12 | 2004-02-08 | Hoffmann La Roche | 6-substituted pyrido-pyrimidines |
| DK1470124T3 (da) * | 2002-01-22 | 2006-04-18 | Warner Lambert Co | 2-(Pyridin-2-yl amino)-pyrido[2,3]pyrimidin-7-oner |
| FR2897336B1 (fr) | 2006-02-10 | 2010-07-30 | Ranger France | Support d'aile pour vehicule automobile |
-
2004
- 2004-11-04 PL PL04797601T patent/PL1685131T3/pl unknown
- 2004-11-04 CA CA002544247A patent/CA2544247A1/en not_active Abandoned
- 2004-11-04 DE DE602004005238T patent/DE602004005238T2/de active Active
- 2004-11-04 AT AT04797601T patent/ATE356124T1/de active
- 2004-11-04 WO PCT/EP2004/012475 patent/WO2005047284A1/en active IP Right Grant
- 2004-11-04 AU AU2004289428A patent/AU2004289428B2/en not_active Ceased
- 2004-11-04 NZ NZ546634A patent/NZ546634A/en not_active IP Right Cessation
- 2004-11-04 DK DK04797601T patent/DK1685131T3/da active
- 2004-11-04 PT PT04797601T patent/PT1685131E/pt unknown
- 2004-11-04 JP JP2006538744A patent/JP4616839B2/ja not_active Expired - Fee Related
- 2004-11-04 CN CNB2004800337221A patent/CN100455582C/zh not_active Expired - Fee Related
- 2004-11-04 ES ES04797601T patent/ES2281843T3/es active Active
- 2004-11-04 SI SI200430261T patent/SI1685131T1/sl unknown
- 2004-11-04 KR KR1020067009146A patent/KR100816321B1/ko not_active IP Right Cessation
- 2004-11-04 BR BRPI0416030-4A patent/BRPI0416030A/pt not_active IP Right Cessation
- 2004-11-04 EP EP04797601A patent/EP1685131B1/en active Active
- 2004-11-04 RU RU2006120486/04A patent/RU2348632C2/ru not_active IP Right Cessation
- 2004-11-09 MY MYPI20044668A patent/MY141011A/en unknown
- 2004-11-10 AR ARP040104138A patent/AR046705A1/es not_active Application Discontinuation
- 2004-11-10 TW TW093134375A patent/TWI349670B/zh not_active IP Right Cessation
- 2004-11-12 US US10/987,656 patent/US7348331B2/en not_active Expired - Fee Related
-
2006
- 2006-04-27 IL IL175284A patent/IL175284A0/en unknown
- 2006-05-12 ZA ZA200603829A patent/ZA200603829B/en unknown
- 2006-05-12 CO CO06045585A patent/CO5690600A2/es not_active Application Discontinuation
- 2006-05-19 NO NO20062256A patent/NO20062256L/no not_active Application Discontinuation
-
2007
- 2007-03-30 HR HR20070132T patent/HRP20070132T3/xx unknown
- 2007-06-18 HK HK07106518.3A patent/HK1099021A1/xx not_active IP Right Cessation
- 2007-11-19 US US11/985,821 patent/US7750016B2/en not_active Expired - Fee Related
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