HRP20040793A2 - Treating benign prostate hyperplasia with sarms - Google Patents

Treating benign prostate hyperplasia with sarms

Info

Publication number
HRP20040793A2
HRP20040793A2 HR20040793A HRP20040793A HRP20040793A2 HR P20040793 A2 HRP20040793 A2 HR P20040793A2 HR 20040793 A HR20040793 A HR 20040793A HR P20040793 A HRP20040793 A HR P20040793A HR P20040793 A2 HRP20040793 A2 HR P20040793A2
Authority
HR
Croatia
Prior art keywords
type
subject
sarm
analog
pharmaceutically acceptable
Prior art date
Application number
HR20040793A
Other languages
English (en)
Croatian (hr)
Inventor
Mitchell
A. Veverka Karen
D. Miller Duane
T. Dalton James
Gao Wenqing
Original Assignee
Gtx Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gtx Inc. filed Critical Gtx Inc.
Publication of HRP20040793A2 publication Critical patent/HRP20040793A2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Surgical Instruments (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
HR20040793A 2002-02-07 2003-02-06 Treating benign prostate hyperplasia with sarms HRP20040793A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35430002P 2002-02-07 2002-02-07
US36299702P 2002-03-11 2002-03-11
PCT/US2003/003447 WO2003065992A2 (en) 2002-02-07 2003-02-06 Treating benign prostate hyperplasia with sarms

Publications (1)

Publication Number Publication Date
HRP20040793A2 true HRP20040793A2 (en) 2006-10-31

Family

ID=27737453

Family Applications (2)

Application Number Title Priority Date Filing Date
HR20040793A HRP20040793A2 (en) 2002-02-07 2003-02-06 Treating benign prostate hyperplasia with sarms
HR20100067A HRP20100067A2 (hr) 2002-02-07 2003-02-06 Liječenje benigne hiperplazije prostate selektivnim modulatorima androgenih receptora

Family Applications After (1)

Application Number Title Priority Date Filing Date
HR20100067A HRP20100067A2 (hr) 2002-02-07 2003-02-06 Liječenje benigne hiperplazije prostate selektivnim modulatorima androgenih receptora

Country Status (20)

Country Link
US (2) US7776921B2 (enExample)
EP (1) EP1480634B1 (enExample)
JP (3) JP4677516B2 (enExample)
KR (2) KR101032661B1 (enExample)
CN (2) CN101732298B (enExample)
AT (1) ATE518537T1 (enExample)
AU (2) AU2003216174C1 (enExample)
BR (1) BRPI0307699A2 (enExample)
CA (2) CA2689080C (enExample)
CY (1) CY1111917T1 (enExample)
DK (1) DK1480634T3 (enExample)
EA (2) EA200901492A1 (enExample)
GE (1) GEP20074122B (enExample)
HR (2) HRP20040793A2 (enExample)
IL (2) IL163380A (enExample)
MX (1) MXPA04007639A (enExample)
PT (1) PT1480634E (enExample)
RS (1) RS69704A (enExample)
TW (2) TW200918043A (enExample)
WO (1) WO2003065992A2 (enExample)

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US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
KR101264820B1 (ko) 2006-08-24 2013-05-22 유니버시티 오브 테네시 리서치 파운데이션 치환된 아실아닐리드 및 그의 사용 방법
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US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US7968603B2 (en) 2007-09-11 2011-06-28 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
JP2015509538A (ja) * 2012-03-07 2015-03-30 リガンド・ファーマシューティカルズ・インコーポレイテッド １つに統合された恒常性システムとしてのステロイドホルモン経路およびコレステロール経路
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Also Published As

Publication number Publication date
HK1068103A1 (en) 2005-04-22
AU2003216174B8 (en) 2009-01-15
JP2005522431A (ja) 2005-07-28
TWI374737B (en) 2012-10-21
JP2010209102A (ja) 2010-09-24
WO2003065992A3 (en) 2004-02-26
IL163380A (en) 2010-06-30
CA2689080A1 (en) 2003-08-14
DK1480634T3 (da) 2011-11-14
GEP20074122B (en) 2007-06-11
CN101732298B (zh) 2012-09-19
CA2689080C (en) 2011-07-05
BRPI0307699A2 (pt) 2015-06-16
JP4677516B2 (ja) 2011-04-27
CN1646115B (zh) 2010-06-09
CY1111917T1 (el) 2015-11-04
CA2475108A1 (en) 2003-08-14
EA013399B1 (ru) 2010-04-30
KR20040089606A (ko) 2004-10-21
WO2003065992A2 (en) 2003-08-14
US20040053897A1 (en) 2004-03-18
EA200901492A1 (ru) 2010-08-30
IL202675A (en) 2011-06-30
AU2003216174B2 (en) 2008-12-18
MXPA04007639A (es) 2005-07-13
EP1480634A4 (en) 2008-01-16
PT1480634E (pt) 2011-10-12
AU2003216174A1 (en) 2003-09-02
RS69704A (sr) 2006-12-15
EP1480634B1 (en) 2011-08-03
TW200307537A (en) 2003-12-16
JP2013144713A (ja) 2013-07-25
HRP20100067A2 (hr) 2010-04-30
CN101732298A (zh) 2010-06-16
KR101032661B1 (ko) 2011-05-06
US8088828B2 (en) 2012-01-03
ATE518537T1 (de) 2011-08-15
EP1480634A2 (en) 2004-12-01
AU2009201084A1 (en) 2009-04-09
EA200401043A1 (ru) 2005-06-30
AU2003216174C1 (en) 2010-01-28
KR20100112659A (ko) 2010-10-19
TW200918043A (en) 2009-05-01
US7776921B2 (en) 2010-08-17
CN1646115A (zh) 2005-07-27
US20100280107A1 (en) 2010-11-04

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