HRP20040352B1 - Use of flibanserin in the treatment of sexual disorders - Google Patents
Use of flibanserin in the treatment of sexual disordersInfo
- Publication number
- HRP20040352B1 HRP20040352B1 HR20040352A HRP20040352A HRP20040352B1 HR P20040352 B1 HRP20040352 B1 HR P20040352B1 HR 20040352 A HR20040352 A HR 20040352A HR P20040352 A HRP20040352 A HR P20040352A HR P20040352 B1 HRP20040352 B1 HR P20040352B1
- Authority
- HR
- Croatia
- Prior art keywords
- flibanserin
- treatment
- sexual disorders
- medicament
- optionally
- Prior art date
Links
- PPRRDFIXUUSXRA-UHFFFAOYSA-N flibanserin Chemical compound FC(F)(F)C1=CC=CC(N2CCN(CCN3C(NC4=CC=CC=C43)=O)CC2)=C1 PPRRDFIXUUSXRA-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002053 flibanserin Drugs 0.000 title abstract 2
- 208000012201 sexual and gender identity disease Diseases 0.000 title 1
- 208000015891 sexual disease Diseases 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01125020 | 2001-10-20 | ||
PCT/EP2002/011103 WO2003035072A1 (en) | 2001-10-20 | 2002-10-04 | Use of flibanserin in the treatment of sexual disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP20040352A2 HRP20040352A2 (en) | 2005-02-28 |
HRP20040352B1 true HRP20040352B1 (en) | 2012-02-29 |
Family
ID=8179028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20040352A HRP20040352B1 (en) | 2001-10-20 | 2004-04-19 | Use of flibanserin in the treatment of sexual disorders |
Country Status (31)
Country | Link |
---|---|
US (9) | US7151103B2 (es) |
EP (2) | EP1446122B1 (es) |
JP (3) | JP2005506370A (es) |
KR (3) | KR20090130196A (es) |
CN (4) | CN101347431A (es) |
AR (2) | AR037109A1 (es) |
AT (1) | ATE327757T1 (es) |
AU (1) | AU2002333894B2 (es) |
BR (1) | BR0213358A (es) |
CA (1) | CA2458067C (es) |
CY (1) | CY1105082T1 (es) |
DE (1) | DE60211937T2 (es) |
DK (1) | DK1446122T5 (es) |
EA (1) | EA007274B1 (es) |
EC (1) | ECSP045069A (es) |
ES (1) | ES2266632T3 (es) |
HR (1) | HRP20040352B1 (es) |
HU (1) | HUP0401023A3 (es) |
IL (2) | IL160389A0 (es) |
ME (1) | MEP42808A (es) |
MX (1) | MXPA04003666A (es) |
MY (1) | MY127290A (es) |
NO (1) | NO325556B1 (es) |
NZ (1) | NZ532079A (es) |
PL (1) | PL208744B1 (es) |
PT (1) | PT1446122E (es) |
RS (1) | RS50876B (es) |
SI (1) | SI1446122T1 (es) |
UA (1) | UA78974C2 (es) |
WO (1) | WO2003035072A1 (es) |
ZA (1) | ZA200401366B (es) |
Families Citing this family (45)
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US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
UA78974C2 (en) * | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
US20040048877A1 (en) * | 2002-05-22 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions containing flibanserin |
BRPI0411985A (pt) * | 2003-07-16 | 2006-08-29 | Pfizer | tratamento da disfunção sexual |
US20050065158A1 (en) * | 2003-07-16 | 2005-03-24 | Pfizer Inc. | Treatment of sexual dysfunction |
WO2005030148A2 (en) | 2003-09-25 | 2005-04-07 | Cenomed, Inc. | Tetrahydroindolone derivatives for treatment of neurological conditions |
US7649002B2 (en) | 2004-02-04 | 2010-01-19 | Pfizer Inc | (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists |
US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
NZ551340A (en) * | 2004-04-22 | 2010-10-29 | Boehringer Ingelheim Int | Pharmaceutical composition comprising flibanserin and a melanocortin agonist for the treatment of premenstrual disorder or sexual aversion disorder |
KR101292492B1 (ko) | 2004-05-11 | 2013-08-01 | 이모셔널 브레인 비.브이. | 약제학적 제형물 및 여성 성기능 부전의 치료에서 그것의용도 |
US20060025420A1 (en) * | 2004-07-30 | 2006-02-02 | Boehringer Ingelheimn International GmbH | Pharmaceutical compositions for the treatment of female sexual disorders |
CA2576812A1 (en) * | 2004-09-03 | 2006-03-09 | Boehringer Ingelheim International Gmbh | Method for the treatment of attention deficit hyperactivity disorder |
EP1858515A2 (en) * | 2005-03-04 | 2007-11-28 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders |
WO2006096439A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases |
JP2008538741A (ja) * | 2005-03-04 | 2008-11-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 鬱病の治療用及び/又は予防用の医薬組成物 |
EP1904182A2 (en) * | 2005-05-06 | 2008-04-02 | Boehringer Ingelheim International GmbH | Method for the treatment of drug abuse with flibanserin |
CA2608363A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of drug-induced sexual dysfunction |
WO2006125041A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of sexual dysfunctions due to medical conditions |
EP1940404A2 (en) * | 2005-07-12 | 2008-07-09 | Boehringer Ingelheim International GmbH | Pharmaceutical composition comprising 2,3-disubstituted tropanes for the treatment of disorders of sexual desire |
PL1912650T3 (pl) | 2005-08-03 | 2018-01-31 | Sprout Pharmaceuticals Inc | Zastosowanie flibanseryny w leczeniu otyłości |
WO2007048803A1 (en) | 2005-10-29 | 2007-05-03 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
US20070123540A1 (en) * | 2005-10-29 | 2007-05-31 | Angelo Ceci | Sexual desire enhancing medicaments comprising benzimidazolone derivatives |
US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
EP1790343A1 (en) | 2005-11-11 | 2007-05-30 | Emotional Brain B.V. | Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction |
US8349850B2 (en) | 2006-03-28 | 2013-01-08 | Atir Holding S.A. | Heterocyclic compounds and uses thereof in the treatment of sexual disorders |
PT2021006E (pt) * | 2006-05-09 | 2015-11-12 | Sprout Pharmaceuticals Inc | Uso de flibanserina para o tratamento de distúrbios de desejo sexual pós-menopausa |
US20090312242A1 (en) * | 2006-06-30 | 2009-12-17 | Ramiro Castro | Flibanserin for the treatment of urinary incontinence and related diseases |
EP2043649A2 (en) * | 2006-07-14 | 2009-04-08 | Boehringer Ingelheim International GmbH | Combinations of flibanserin with caffeine, process for their preparation and use thereof as medicaments |
JP2009543839A (ja) * | 2006-07-14 | 2009-12-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 女性の性的障害を治療するためのフリバンセリンの使用 |
WO2008019996A2 (en) | 2006-08-14 | 2008-02-21 | Boehringer Ingelheim International Gmbh | Formulations of flibanserin and method for manufacturing the same |
CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
KR20090045945A (ko) | 2006-08-25 | 2009-05-08 | 베링거 인겔하임 인터내셔날 게엠베하 | 제어 방출 시스템 및 이의 제조방법 |
EP1925307A1 (en) * | 2006-11-03 | 2008-05-28 | Emotional Brain B.V. | Use of 3-alpha-androstanediol in the treatment of sexual dysfunction |
WO2008074795A1 (en) | 2006-12-20 | 2008-06-26 | Boehringer Ingelheim International Gmbh | Sulfated benzimidazolone derivatives having mixed serotonine receptor affinity |
US8304601B2 (en) * | 2007-01-23 | 2012-11-06 | Keiko Fujikawa | Mouse model for eye disease |
EP2129400A2 (en) * | 2007-03-28 | 2009-12-09 | Boehringer Ingelheim International GmbH | Pharmaceutical compositions comprising flibanserin and a further agent in the treatment of sexual disorders |
PE20091188A1 (es) * | 2007-09-12 | 2009-08-31 | Boehringer Ingelheim Int | Compuesto 1-[2-(4-(3-trifluorometil-fenil)piperazin-1-il)etil]-2,3-dihidro-1h-benzimidazol-2-ona (flibanserina), sus sales de adicion y composiciones farmaceuticas que los contienen |
CA2686480A1 (en) | 2008-12-15 | 2010-06-15 | Boehringer Ingelheim International Gmbh | New salts |
DE102011012712A1 (de) | 2011-03-01 | 2012-09-06 | Frank Lehmann-Horn | Verwendung von Aldosteron-Rezeptor-Antagonisten zur Behandlung von weiblicher sexueller Dysfunktion |
US9353067B2 (en) | 2011-04-10 | 2016-05-31 | Atir Holding S.A. | Heterocyclic compounds and uses thereof in the treatment of sexual disorders |
EP2879680A4 (en) * | 2012-08-06 | 2016-06-01 | S1 Biopharma Inc | TREATMENT REGIMES |
CN104926734B (zh) * | 2015-07-07 | 2017-04-05 | 苏州立新制药有限公司 | 氟班色林的制备方法 |
WO2017100324A1 (en) * | 2015-12-10 | 2017-06-15 | Repros Therapeutics Inc. | Combination therapy for treating female hypoactive sexual desire disorders |
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