HRP20030583B1 - Postupak priprave imidazotriazinona supstituiranih sulfinamidom - Google Patents

Postupak priprave imidazotriazinona supstituiranih sulfinamidom

Info

Publication number
HRP20030583B1
HRP20030583B1 HR20030583A HRP20030583A HRP20030583B1 HR P20030583 B1 HRP20030583 B1 HR P20030583B1 HR 20030583 A HR20030583 A HR 20030583A HR P20030583 A HRP20030583 A HR P20030583A HR P20030583 B1 HRP20030583 B1 HR P20030583B1
Authority
HR
Croatia
Prior art keywords
straight
carbon atoms
chain
hydroxyl
formula
Prior art date
Application number
HR20030583A
Other languages
English (en)
Croatian (hr)
Inventor
Nowakowski Marc
Gehring Reinhold
Heilmann Werner
Wahl Karl-Heinz
Original Assignee
Bayer Schering Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Aktiengesellschaft filed Critical Bayer Schering Pharma Aktiengesellschaft
Publication of HRP20030583A2 publication Critical patent/HRP20030583A2/hr
Publication of HRP20030583B1 publication Critical patent/HRP20030583B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR20030583A 2000-12-18 2001-12-05 Postupak priprave imidazotriazinona supstituiranih sulfinamidom HRP20030583B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10063108A DE10063108A1 (de) 2000-12-18 2000-12-18 Verfahren zur Herstellung von Sulfonamid-substituierten Imidazotriazinonen
PCT/EP2001/014239 WO2002050076A2 (de) 2000-12-18 2001-12-05 Verfahren zur herstellung von sulfonamid-substituierten imidazotriazinonen

Publications (2)

Publication Number Publication Date
HRP20030583A2 HRP20030583A2 (en) 2005-06-30
HRP20030583B1 true HRP20030583B1 (hr) 2011-09-30

Family

ID=7667666

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030583A HRP20030583B1 (hr) 2000-12-18 2001-12-05 Postupak priprave imidazotriazinona supstituiranih sulfinamidom

Country Status (42)

Country Link
US (3) US6777551B2 (cs)
EP (1) EP1345939B1 (cs)
JP (1) JP4441175B2 (cs)
KR (1) KR100787288B1 (cs)
CN (1) CN1227253C (cs)
AR (1) AR032775A1 (cs)
AT (1) ATE328885T1 (cs)
AU (2) AU1708902A (cs)
BG (1) BG66142B1 (cs)
BR (1) BRPI0116227B8 (cs)
CA (1) CA2431933C (cs)
CU (2) CU23341B7 (cs)
CY (1) CY1105197T1 (cs)
CZ (1) CZ297005B6 (cs)
DE (2) DE10063108A1 (cs)
DK (1) DK1345939T3 (cs)
DO (1) DOP2001000295A (cs)
EC (1) ECSP034657A (cs)
EE (1) EE05308B1 (cs)
ES (1) ES2266098T3 (cs)
GT (1) GT200100251A (cs)
HN (1) HN2001000278A (cs)
HR (1) HRP20030583B1 (cs)
HU (1) HU229296B1 (cs)
IL (2) IL156278A0 (cs)
MA (1) MA25927A1 (cs)
MX (1) MXPA03005429A (cs)
MY (1) MY126689A (cs)
NO (1) NO325398B1 (cs)
NZ (1) NZ526477A (cs)
PE (1) PE20020590A1 (cs)
PL (1) PL207294B1 (cs)
PT (1) PT1345939E (cs)
RU (1) RU2299211C2 (cs)
SI (1) SI1345939T1 (cs)
SK (1) SK286894B6 (cs)
SV (1) SV2003000766A (cs)
TW (1) TWI289562B (cs)
UA (1) UA75109C2 (cs)
UY (2) UY27070A1 (cs)
WO (1) WO2002050076A2 (cs)
ZA (1) ZA200304705B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10063108A1 (de) * 2000-12-18 2002-06-20 Bayer Ag Verfahren zur Herstellung von Sulfonamid-substituierten Imidazotriazinonen
DE10107639A1 (de) * 2001-02-15 2002-08-22 Bayer Ag 2-Alkoxyphenyl-substituierte Imidazotriazinone
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE202004006552U1 (de) * 2004-04-26 2004-07-08 Knürr AG Kühlungssystem für Geräte- und Netzwerkschränke
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
US7977478B2 (en) * 2006-03-13 2011-07-12 Dr. Reddy's Laboratories Limited Polymorphic forms of vardenafil
CN101965348B (zh) * 2007-09-06 2013-11-13 上海特化医药科技有限公司 伐地那非的制备方法及其中间体
WO2009082845A1 (fr) 2007-12-28 2009-07-09 Topharman Shanghai Co., Ltd. N-{1-[3-(2-éthoxy-5-(4-éthylpipérazinyl)benzènesulfonyl)-4,5-dihydro-5-oxo-1,2,4-triazin-6-yl]éthyl}butyramide, son procédé de préparation et son utilisation
WO2011016016A1 (en) 2009-08-07 2011-02-10 Ranbaxy Laboratories Limited Processes for the preparation of vardenafil
PL390079A1 (pl) * 2009-12-30 2011-07-04 Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna Sposób otrzymywania wardenafilu i jego izolacji jako soli z kwasem cytrynowym oraz krystaliczna postać tej soli
CN102134242B (zh) 2011-01-21 2013-08-28 浙江大德药业集团有限公司 一种用于治疗阳痿的快速长效的化合物
CZ2011767A3 (cs) * 2011-11-24 2013-06-05 Zentiva, K.S. Zpusob prípravy a izolace solí vardenafilu s kyselinami
US20160317542A1 (en) 2013-12-09 2016-11-03 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
PL223869B1 (pl) 2013-12-16 2016-11-30 Starogardzkie Zakłady Farm Polpharma Spółka Akcyjna Sposób otrzymywania wardenafilu i jego soli
CN107383020A (zh) * 2017-07-29 2017-11-24 合肥创新医药技术有限公司 一种伐地那非杂质的制备方法
CN111655229A (zh) 2017-12-20 2020-09-11 卡里亚制药控股有限公司 包含伐地那非的薄膜制剂、其制备方法及其用途
CN115043757B (zh) * 2022-07-27 2023-08-08 南京桦冠生物技术有限公司 一种连续化制备苄脒盐酸盐的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999024433A1 (de) * 1997-11-12 1999-05-20 Bayer Aktiengesellschaft 2-phenyl-substituierte imidazotriazinone als phosphodiesterase inhibitoren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9311920D0 (en) * 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
DE10063108A1 (de) * 2000-12-18 2002-06-20 Bayer Ag Verfahren zur Herstellung von Sulfonamid-substituierten Imidazotriazinonen
DE10107639A1 (de) * 2001-02-15 2002-08-22 Bayer Ag 2-Alkoxyphenyl-substituierte Imidazotriazinone

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999024433A1 (de) * 1997-11-12 1999-05-20 Bayer Aktiengesellschaft 2-phenyl-substituierte imidazotriazinone als phosphodiesterase inhibitoren

Also Published As

Publication number Publication date
WO2002050076A2 (de) 2002-06-27
SV2003000766A (es) 2003-01-13
EP1345939A2 (de) 2003-09-24
ES2266098T3 (es) 2007-03-01
JP4441175B2 (ja) 2010-03-31
AU2002217089B2 (en) 2006-01-12
CZ297005B6 (cs) 2006-08-16
CY1105197T1 (el) 2010-03-03
HUP0302467A2 (hu) 2003-11-28
MA25927A1 (fr) 2003-10-01
NO20032731D0 (no) 2003-06-16
PL207294B1 (pl) 2010-11-30
ZA200304705B (en) 2004-08-12
US6998483B2 (en) 2006-02-14
US20020137930A1 (en) 2002-09-26
DE10063108A1 (de) 2002-06-20
WO2002050076A3 (de) 2002-08-29
HN2001000278A (es) 2002-01-30
MY126689A (en) 2006-10-31
NO325398B1 (no) 2008-04-21
MXPA03005429A (es) 2004-05-04
HK1063799A1 (en) 2005-01-14
HU229296B1 (en) 2013-10-28
EE05308B1 (et) 2010-06-15
HUP0302467A3 (en) 2004-11-29
SK286894B6 (sk) 2009-07-06
CU20080213A7 (es) 2012-06-21
TWI289562B (en) 2007-11-11
CA2431933C (en) 2009-12-01
BR0116227B1 (pt) 2014-08-26
BR0116227A (pt) 2003-12-30
ATE328885T1 (de) 2006-06-15
HRP20030583A2 (en) 2005-06-30
UA75109C2 (en) 2006-03-15
NZ526477A (en) 2004-12-24
CA2431933A1 (en) 2002-06-27
BG107892A (bg) 2004-08-31
EE200300294A (et) 2003-10-15
SK7502003A3 (en) 2003-10-07
EP1345939B1 (de) 2006-06-07
IL156278A (en) 2009-06-15
UY37172A (es) 2017-06-30
CZ20031692A3 (cs) 2003-10-15
CU23341B7 (es) 2009-02-20
ECSP034657A (es) 2003-07-25
US20050014756A1 (en) 2005-01-20
US6777551B2 (en) 2004-08-17
PT1345939E (pt) 2006-08-31
DOP2001000295A (es) 2002-12-15
BRPI0116227B8 (pt) 2021-05-25
JP2004517849A (ja) 2004-06-17
IL156278A0 (en) 2004-01-04
CU23873B1 (es) 2013-04-19
UY27070A1 (es) 2002-07-31
DK1345939T3 (da) 2006-09-25
RU2299211C2 (ru) 2007-05-20
CN1481386A (zh) 2004-03-10
PL365310A1 (en) 2004-12-27
KR20030063430A (ko) 2003-07-28
AU1708902A (en) 2002-07-01
CN1227253C (zh) 2005-11-16
KR100787288B1 (ko) 2007-12-20
GT200100251A (es) 2002-10-01
US20050203298A1 (en) 2005-09-15
BG66142B1 (bg) 2011-07-29
SI1345939T1 (sl) 2006-10-31
AR032775A1 (es) 2003-11-26
DE50110080D1 (de) 2006-07-20
PE20020590A1 (es) 2002-07-13
NO20032731L (no) 2003-06-16

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