HRP20030419A2 - Combination of gaba agonists and aldose reductase inhibitors - Google Patents
Combination of gaba agonists and aldose reductase inhibitors Download PDFInfo
- Publication number
- HRP20030419A2 HRP20030419A2 HR20030419A HRP20030419A HRP20030419A2 HR P20030419 A2 HRP20030419 A2 HR P20030419A2 HR 20030419 A HR20030419 A HR 20030419A HR P20030419 A HRP20030419 A HR P20030419A HR P20030419 A2 HRP20030419 A2 HR P20030419A2
- Authority
- HR
- Croatia
- Prior art keywords
- prodrug
- gaba
- agonist
- pharmaceutically acceptable
- acceptable salt
- Prior art date
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Bioinformatics & Cheminformatics (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25044800P | 2000-11-30 | 2000-11-30 | |
| PCT/IB2001/002214 WO2002043763A2 (en) | 2000-11-30 | 2001-11-19 | Combination of gaba agonists and aldose reductase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20030419A2 true HRP20030419A2 (en) | 2004-08-31 |
Family
ID=22947799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20030419A HRP20030419A2 (en) | 2000-11-30 | 2003-05-22 | Combination of gaba agonists and aldose reductase inhibitors |
Country Status (34)
| Country | Link |
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| US (1) | US6720348B2 (sk) |
| EP (1) | EP1337272A2 (sk) |
| JP (1) | JP2004514700A (sk) |
| KR (1) | KR20030059287A (sk) |
| CN (1) | CN1477976A (sk) |
| AP (1) | AP2001002359A0 (sk) |
| AR (1) | AR031432A1 (sk) |
| AU (1) | AU2002215160A1 (sk) |
| BG (1) | BG107812A (sk) |
| BR (1) | BR0115776A (sk) |
| CA (1) | CA2430309A1 (sk) |
| CR (1) | CR6962A (sk) |
| CZ (1) | CZ20031387A3 (sk) |
| DO (1) | DOP2001000294A (sk) |
| EA (1) | EA200300433A1 (sk) |
| EC (1) | ECSP034629A (sk) |
| EE (1) | EE200300249A (sk) |
| HR (1) | HRP20030419A2 (sk) |
| HU (1) | HUP0302555A3 (sk) |
| IL (1) | IL155710A0 (sk) |
| IS (1) | IS6787A (sk) |
| MA (1) | MA26965A1 (sk) |
| MX (1) | MXPA03004871A (sk) |
| NO (1) | NO20032387D0 (sk) |
| OA (1) | OA12413A (sk) |
| PA (1) | PA8534201A1 (sk) |
| PE (1) | PE20020598A1 (sk) |
| PL (1) | PL365378A1 (sk) |
| SK (1) | SK6092003A3 (sk) |
| SV (1) | SV2003000752A (sk) |
| TN (1) | TNSN01170A1 (sk) |
| UY (1) | UY27044A1 (sk) |
| WO (1) | WO2002043763A2 (sk) |
| ZA (1) | ZA200303340B (sk) |
Families Citing this family (25)
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|---|---|---|---|---|
| NZ332762A (en) | 1996-07-24 | 2000-09-29 | Warner Lambert Co | Isobutylgaba and its derivatives for the treatment of pain |
| US6696407B1 (en) * | 1997-03-21 | 2004-02-24 | The Regents Of The University Of California | Huntington's disease treatment comprising administering aldose reductase inhibitors to increase striatal CNTF |
| US20030162754A1 (en) * | 2001-12-17 | 2003-08-28 | Tufts University | Use of GABA and GABAB agonists |
| WO2003105864A1 (en) * | 2002-06-13 | 2003-12-24 | Board Of Regents, The University Of Texas System | Methods and compositions involving aldose reductase inhibitors |
| KR20090118994A (ko) * | 2002-12-13 | 2009-11-18 | 워너-램버트 캄파니 엘엘씨 | 하부요로증상을 치료하기 위한 알파-2-델타 리간드 |
| US20080318908A1 (en) * | 2002-12-17 | 2008-12-25 | Trustees Of Tufts College | Use of gaba and gabab agonists |
| EP1480631B1 (en) * | 2002-12-20 | 2007-08-01 | Dynogen Pharmaceuticals Inc. | Methods of treating non-painful bladder disorders using alpha2-delta- subunit calcium channel modulators |
| KR100742001B1 (ko) * | 2003-03-21 | 2007-07-23 | 다이노젠 파마세우티컬스, 인코포레이티드 | 평활근 모듈레이터 및 알파2 델타 서브유닛 칼슘 채널모듈레이터를 이용한 하부 요로 질환의 치료 방법 |
| KR20050036195A (ko) * | 2003-10-15 | 2005-04-20 | 고재영 | 신규한 망막병증 치료제 조성물 |
| US20110092566A1 (en) * | 2004-11-19 | 2011-04-21 | Srivastava Satish K | Treatment of cancer with aldose reductase inhibitors |
| WO2007053596A1 (en) * | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| MX2008013137A (es) | 2006-04-11 | 2008-10-21 | Novartis Ag | Compuestos organicos. |
| WO2008077597A1 (en) * | 2006-12-22 | 2008-07-03 | Novartis Ag | 1-aminomethyl- l- phenyl- cyclohexane derivatives as ddp-iv inhibitors |
| EP2848252A3 (en) | 2007-03-23 | 2015-06-17 | The Board of Regents of the University of Texas System | Aldose reductase inhibitors for use in treating uveitis |
| US20090270490A1 (en) * | 2008-04-24 | 2009-10-29 | The Board Of Regents Of The University Of Texas System | Methods involving aldose reductase inhibition |
| JP2010043063A (ja) | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
| EP2309858A4 (en) | 2008-07-31 | 2011-09-14 | Dekel Pharmaceuticals Ltd | COMPOSITIONS AND METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES |
| EA016904B1 (ru) * | 2008-09-06 | 2012-08-30 | Бионевия Фармасьютикалс, Инк. | Новый холиновый сокристалл эпалрестата |
| CN103547261A (zh) | 2010-12-23 | 2014-01-29 | 德克萨斯大学系统董事会 | 用于治疗copd的方法 |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| US20180161388A1 (en) * | 2015-05-18 | 2018-06-14 | Beth Israel Deaconess Medical Center, Inc. | Substance p, mast cell degranulation inhibitors, and peripheral neuropathy |
| MX2019012476A (es) * | 2017-04-21 | 2020-02-12 | Hoffman Steven | Composiciones y metodos para tratar la retinopatia. |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| EP3955918A1 (en) | 2019-04-17 | 2022-02-23 | COMPASS Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
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| CH449645A (de) | 1963-07-09 | 1968-01-15 | Ciba Geigy | Verfahren zur Herstellung neuer Aminosäuren |
| CH427803A (de) | 1963-12-06 | 1967-01-15 | Geigy Ag J R | Verfahren zur Herstellung eines neuen Isoxazolderivates |
| DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US3960927A (en) | 1975-03-18 | 1976-06-01 | Richardson-Merrell Inc. | Olefinic derivatives of amino acids |
| FR2319338A1 (fr) | 1975-08-01 | 1977-02-25 | Synthelabo | Nouveaux derives de a- phenyl benzylideniques des acides amines, leur preparation et les medicaments qui en contiennent |
| US4130714A (en) | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| CS234018B2 (en) | 1979-06-01 | 1985-03-14 | Wellcome Found | Method of 3,5-diammino-6-1,2,4-triazine derivatives making |
| JPS5745185A (en) | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
| US4791126A (en) | 1980-08-22 | 1988-12-13 | Ono Pharmaceutical Co., Ltd. | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredients |
| JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
| FR2492258A1 (fr) | 1980-10-17 | 1982-04-23 | Pharmindustrie | Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole |
| CA1176269A (en) | 1981-03-02 | 1984-10-16 | Kazimir Sestanj | N-naphthoylglycine derivatives |
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| GB8801037D0 (en) | 1988-01-18 | 1988-02-17 | Plessey Co Ltd | Improvements relating to fuel supply systems |
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| US4996204A (en) * | 1989-05-11 | 1991-02-26 | Pfizer Inc. | Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors |
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| GB0001662D0 (en) * | 1999-02-06 | 2000-03-15 | Zeneca Ltd | Pharmaceutical compositions |
| US6350769B1 (en) * | 1999-02-24 | 2002-02-26 | The Regents Of The University Of California | Gaba alpha receptors mediate inhibition of T cell responses |
| DK1041068T3 (da) * | 1999-04-01 | 2004-05-10 | Pfizer Prod Inc | Compounds for treating and preventing diabetic complications |
| NZ514813A (en) * | 1999-04-08 | 2004-12-24 | Ortho Mcneil Pharm Inc | Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders |
-
2001
- 2001-11-19 HU HU0302555A patent/HUP0302555A3/hu unknown
- 2001-11-19 EE EEP200300249A patent/EE200300249A/xx unknown
- 2001-11-19 CA CA002430309A patent/CA2430309A1/en not_active Abandoned
- 2001-11-19 CZ CZ20031387A patent/CZ20031387A3/cs unknown
- 2001-11-19 JP JP2002545733A patent/JP2004514700A/ja not_active Withdrawn
- 2001-11-19 AP APAP/P/2001/002359A patent/AP2001002359A0/en unknown
- 2001-11-19 WO PCT/IB2001/002214 patent/WO2002043763A2/en not_active Application Discontinuation
- 2001-11-19 OA OA1200300138A patent/OA12413A/en unknown
- 2001-11-19 SK SK609-2003A patent/SK6092003A3/sk not_active Application Discontinuation
- 2001-11-19 BR BR0115776-0A patent/BR0115776A/pt not_active IP Right Cessation
- 2001-11-19 KR KR10-2003-7007221A patent/KR20030059287A/ko not_active Application Discontinuation
- 2001-11-19 EP EP01983740A patent/EP1337272A2/en not_active Withdrawn
- 2001-11-19 AU AU2002215160A patent/AU2002215160A1/en not_active Abandoned
- 2001-11-19 IL IL15571001A patent/IL155710A0/xx unknown
- 2001-11-19 EA EA200300433A patent/EA200300433A1/ru unknown
- 2001-11-19 CN CNA018195954A patent/CN1477976A/zh active Pending
- 2001-11-19 PL PL01365378A patent/PL365378A1/xx not_active Application Discontinuation
- 2001-11-19 MX MXPA03004871A patent/MXPA03004871A/es unknown
- 2001-11-26 DO DO2001000294A patent/DOP2001000294A/es unknown
- 2001-11-27 PE PE2001001187A patent/PE20020598A1/es not_active Application Discontinuation
- 2001-11-28 AR ARP010105542A patent/AR031432A1/es not_active Application Discontinuation
- 2001-11-28 UY UY27044A patent/UY27044A1/es not_active Application Discontinuation
- 2001-11-29 US US09/997,039 patent/US6720348B2/en not_active Expired - Fee Related
- 2001-11-29 TN TNTNSN01170A patent/TNSN01170A1/fr unknown
- 2001-11-30 SV SV2001000752A patent/SV2003000752A/es unknown
- 2001-11-30 PA PA20018534201A patent/PA8534201A1/es unknown
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2003
- 2003-04-14 IS IS6787A patent/IS6787A/is unknown
- 2003-04-24 CR CR6962A patent/CR6962A/es not_active Application Discontinuation
- 2003-04-30 ZA ZA200303340A patent/ZA200303340B/en unknown
- 2003-05-13 BG BG107812A patent/BG107812A/bg unknown
- 2003-05-20 MA MA27166A patent/MA26965A1/fr unknown
- 2003-05-22 HR HR20030419A patent/HRP20030419A2/hr not_active Application Discontinuation
- 2003-05-27 NO NO20032387A patent/NO20032387D0/no not_active Application Discontinuation
- 2003-05-28 EC EC2003004629A patent/ECSP034629A/es unknown
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