HRP20030194A2 - Use of triazinetrione sulfones for combating coccidiosis - Google Patents
Use of triazinetrione sulfones for combating coccidiosis Download PDFInfo
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- HRP20030194A2 HRP20030194A2 HR20030194A HRP20030194A HRP20030194A2 HR P20030194 A2 HRP20030194 A2 HR P20030194A2 HR 20030194 A HR20030194 A HR 20030194A HR P20030194 A HRP20030194 A HR P20030194A HR P20030194 A2 HRP20030194 A2 HR P20030194A2
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- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229960005358 monensin Drugs 0.000 description 1
- GAOZTHIDHYLHMS-KEOBGNEYSA-N monensin A Chemical compound C([C@@](O1)(C)[C@H]2CC[C@@](O2)(CC)[C@H]2[C@H](C[C@@H](O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C[C@@]21C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C(O)=O)O2 GAOZTHIDHYLHMS-KEOBGNEYSA-N 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 239000003883 ointment base Substances 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- JCGNDDUYTRNOFT-UHFFFAOYSA-N oxolane-2,4-dione Chemical compound O=C1COC(=O)C1 JCGNDDUYTRNOFT-UHFFFAOYSA-N 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920000151 polyglycol Polymers 0.000 description 1
- 239000010695 polyglycol Substances 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- RWPGFSMJFRPDDP-UHFFFAOYSA-L potassium metabisulfite Chemical compound [K+].[K+].[O-]S(=O)S([O-])(=O)=O RWPGFSMJFRPDDP-UHFFFAOYSA-L 0.000 description 1
- 229940043349 potassium metabisulfite Drugs 0.000 description 1
- 235000010263 potassium metabisulphite Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- ZPWFUIUNWDIYCJ-UHFFFAOYSA-N propan-2-yl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC(C)C ZPWFUIUNWDIYCJ-UHFFFAOYSA-N 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 239000011814 protection agent Substances 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
- RNVYQYLELCKWAN-UHFFFAOYSA-N solketal Chemical compound CC1(C)OCC(CO)O1 RNVYQYLELCKWAN-UHFFFAOYSA-N 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- JNYAEWCLZODPBN-CTQIIAAMSA-N sorbitan Polymers OCC(O)C1OCC(O)[C@@H]1O JNYAEWCLZODPBN-CTQIIAAMSA-N 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000003046 sporozoite Anatomy 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical class [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- UWHCKJMYHZGTIT-UHFFFAOYSA-N tetraethylene glycol Chemical compound OCCOCCOCCOCCO UWHCKJMYHZGTIT-UHFFFAOYSA-N 0.000 description 1
- BSYVTEYKTMYBMK-UHFFFAOYSA-N tetrahydrofurfuryl alcohol Chemical compound OCC1CCCO1 BSYVTEYKTMYBMK-UHFFFAOYSA-N 0.000 description 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 231100000048 toxicity data Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 235000019386 wax ester Nutrition 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/30—Only oxygen atoms
- C07D251/34—Cyanuric or isocyanuric esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10040174A DE10040174A1 (de) | 2000-08-17 | 2000-08-17 | Verwendung von Triazintrion-Sulfonen zur Bekämpfung von Coccidiosen |
| PCT/EP2001/009060 WO2002014288A1 (de) | 2000-08-17 | 2001-08-06 | Verwendung von triazintrion-sulfonen zur bekämpfung von coccidiosen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20030194A2 true HRP20030194A2 (en) | 2005-10-31 |
Family
ID=7652719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20030194A HRP20030194A2 (en) | 2000-08-17 | 2003-03-14 | Use of triazinetrione sulfones for combating coccidiosis |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7915257B2 (sk) |
| EP (1) | EP1311491A1 (sk) |
| JP (1) | JP2004506624A (sk) |
| KR (1) | KR100803078B1 (sk) |
| CN (3) | CN1469868A (sk) |
| AR (1) | AR030378A1 (sk) |
| AU (2) | AU7852201A (sk) |
| BR (1) | BR0113268A (sk) |
| CA (1) | CA2419471C (sk) |
| CZ (1) | CZ300020B6 (sk) |
| DE (1) | DE10040174A1 (sk) |
| HR (1) | HRP20030194A2 (sk) |
| HU (1) | HUP0303701A3 (sk) |
| MX (1) | MXPA03001429A (sk) |
| MY (1) | MY136518A (sk) |
| NO (1) | NO20030585L (sk) |
| NZ (1) | NZ524200A (sk) |
| PL (1) | PL359709A1 (sk) |
| SK (1) | SK1652003A3 (sk) |
| TW (1) | TW200819431A (sk) |
| WO (1) | WO2002014288A1 (sk) |
| YU (1) | YU11703A (sk) |
| ZA (1) | ZA200301225B (sk) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004001558A1 (de) * | 2004-01-10 | 2005-08-18 | Bayer Healthcare Ag | Arzneimittel zur topischen Applikation bei Tieren |
| DE102006038292A1 (de) * | 2006-08-16 | 2008-02-21 | Bayer Healthcare Ag | Transdermale Anwendung von Triazinen zur Bekämpfung von Coccidien-Infektionen |
| DE102007025908A1 (de) * | 2007-06-01 | 2008-12-04 | Bayer Healthcare Ag | Formulierungen enthaltend Triazinone und Eisen |
| SI22751A (sl) * | 2008-04-03 | 2009-10-31 | Krka, D.D., Novo Mesto | Toltrazuril z izboljĺ animi lastnostmi za raztapljanje |
| DE102009012423A1 (de) * | 2009-03-10 | 2010-09-16 | Bayer Animal Health Gmbh | Zubereitung auf Ölbasis |
| EP2740470A1 (en) * | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Treatment of Coccidiosis with intramuscular triazine composition |
| EP2740492A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Triazine formulations with a second active ingredient and surfactant(s) |
| EP2740469A1 (en) * | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | New treatments with triazines |
| CN102973497A (zh) * | 2012-12-13 | 2013-03-20 | 江苏恒丰强生物技术有限公司 | 一种托曲珠利溶液及其制备方法 |
| WO2019162702A1 (en) | 2018-02-26 | 2019-08-29 | AlzeCure Pharma AB | Triazine derivatives for treating diseases relating to neurotrophins |
| EP3578181A1 (en) * | 2018-06-05 | 2019-12-11 | Bayer Animal Health GmbH | Formulation for use in the simultaneous treatment of coccidial infections and iron deficiencies |
| GB201810668D0 (en) | 2018-06-28 | 2018-08-15 | Stiftelsen Alzecure | New compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2413722C3 (de) * | 1974-03-21 | 1982-04-08 | Bayer Ag, 5090 Leverkusen | Neue 1-(4-Phenoxy-phenyl)-1,3,5-triazin-Derivate, ein Verfahren zu ihrer Herstellung sowie ihre Anwendung als Arzneimittel |
| DE2414612A1 (de) | 1974-03-26 | 1975-10-16 | Bayer Ag | 1-aryluracile, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2532363A1 (de) | 1975-07-19 | 1977-02-03 | Bayer Ag | Substituierte 2-phenyl-1,2,4- triazin-3,5(2h,4h)-dione, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2718799A1 (de) * | 1977-04-27 | 1978-11-09 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazin- derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel und wachstumsfoerderer |
| US4255231A (en) * | 1979-06-13 | 1981-03-10 | Congoleum Corporation | Carpet etching |
| DE3314739A1 (de) | 1983-04-23 | 1984-10-25 | Bayer Ag, 5090 Leverkusen | 1-(4-(4-(fluoralkylmethylthio- oder -sulfinyl- oder -sulfonyl-)phenoxy) phenyl)-1,3,5-triazin-2,4,6(1h,3h,5h)-trione, verfahren zu ihrer herstellung und ihre verwendung als coccidiosemittel |
| US4837029A (en) * | 1987-04-06 | 1989-06-06 | Carolina Medical Products, Inc. | Low foaming, aqueously homogenizable rifampin composition |
| US4808404A (en) * | 1988-01-11 | 1989-02-28 | A. H. Robins Company, Inc. | Live vaccine for coccidiosis utilizing coccidial sporozoites |
| DE19824483A1 (de) | 1998-06-02 | 1999-12-09 | Bayer Ag | Halbfeste wäßrige Zubereitungen für orale Applikation von Toltrazuril-Sulfon |
| BR9914385A (pt) | 1998-10-08 | 2001-07-17 | New Ace Res Company | Composição útil para o tratamento e prevenção de infecções protozoárias no homem e em animais, e, método de tratamento de uma infecção protozoária no homem e em animais |
| US6150361A (en) * | 1998-12-22 | 2000-11-21 | Bayer Corporation | Triazineone compounds for treating diseases due to sarcosystis, neospora and toxoplasma |
| CN1331595A (zh) | 1998-12-22 | 2002-01-16 | 美国拜尔公司 | 肉孢子虫属、新孢子虫属(Neospora)和弓形虫属引起的疾病治疗用三嗪酮化合物 |
-
2000
- 2000-08-17 DE DE10040174A patent/DE10040174A1/de not_active Withdrawn
-
2001
- 2001-08-06 US US10/362,038 patent/US7915257B2/en not_active Expired - Lifetime
- 2001-08-06 CZ CZ20030469A patent/CZ300020B6/cs not_active IP Right Cessation
- 2001-08-06 KR KR1020037001319A patent/KR100803078B1/ko not_active IP Right Cessation
- 2001-08-06 BR BR0113268-7A patent/BR0113268A/pt not_active IP Right Cessation
- 2001-08-06 CA CA002419471A patent/CA2419471C/en not_active Expired - Lifetime
- 2001-08-06 CN CNA018175023A patent/CN1469868A/zh active Pending
- 2001-08-06 MX MXPA03001429A patent/MXPA03001429A/es active IP Right Grant
- 2001-08-06 NZ NZ524200A patent/NZ524200A/en unknown
- 2001-08-06 WO PCT/EP2001/009060 patent/WO2002014288A1/de active IP Right Grant
- 2001-08-06 JP JP2002519431A patent/JP2004506624A/ja not_active Withdrawn
- 2001-08-06 CN CNA2008102125294A patent/CN101361743A/zh active Pending
- 2001-08-06 PL PL01359709A patent/PL359709A1/xx not_active Application Discontinuation
- 2001-08-06 YU YU11703A patent/YU11703A/sh unknown
- 2001-08-06 CN CNA2006100588269A patent/CN1853635A/zh active Pending
- 2001-08-06 AU AU7852201A patent/AU7852201A/xx active Pending
- 2001-08-06 SK SK165-2003A patent/SK1652003A3/sk not_active Application Discontinuation
- 2001-08-06 AU AU2001278522A patent/AU2001278522B2/en not_active Ceased
- 2001-08-06 HU HU0303701A patent/HUP0303701A3/hu unknown
- 2001-08-06 EP EP01956583A patent/EP1311491A1/de not_active Withdrawn
- 2001-08-15 MY MYPI20013833A patent/MY136518A/en unknown
- 2001-08-17 TW TW097101085A patent/TW200819431A/zh unknown
- 2001-08-17 AR ARP010103948A patent/AR030378A1/es unknown
-
2003
- 2003-02-06 NO NO20030585A patent/NO20030585L/no not_active Application Discontinuation
- 2003-02-14 ZA ZA200301225A patent/ZA200301225B/en unknown
- 2003-03-14 HR HR20030194A patent/HRP20030194A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002014288A1 (de) | 2002-02-21 |
| CN1469868A (zh) | 2004-01-21 |
| CA2419471A1 (en) | 2003-02-14 |
| AR030378A1 (es) | 2003-08-20 |
| ZA200301225B (en) | 2004-02-16 |
| CA2419471C (en) | 2009-10-13 |
| NO20030585D0 (no) | 2003-02-06 |
| PL359709A1 (en) | 2004-09-06 |
| US20040013699A1 (en) | 2004-01-22 |
| EP1311491A1 (de) | 2003-05-21 |
| SK1652003A3 (en) | 2004-02-03 |
| KR20030017659A (ko) | 2003-03-03 |
| NZ524200A (en) | 2005-02-25 |
| JP2004506624A (ja) | 2004-03-04 |
| CN1853635A (zh) | 2006-11-01 |
| NO20030585L (no) | 2003-02-06 |
| HUP0303701A2 (hu) | 2004-03-29 |
| TW200819431A (en) | 2008-05-01 |
| HUP0303701A3 (en) | 2006-01-30 |
| YU11703A (sh) | 2006-01-16 |
| DE10040174A1 (de) | 2002-02-28 |
| CN101361743A (zh) | 2009-02-11 |
| KR100803078B1 (ko) | 2008-02-18 |
| AU2001278522B9 (en) | 2002-02-25 |
| CZ300020B6 (cs) | 2009-01-14 |
| AU2001278522B2 (en) | 2007-03-22 |
| MXPA03001429A (es) | 2004-05-04 |
| AU7852201A (en) | 2002-02-25 |
| BR0113268A (pt) | 2003-07-08 |
| US7915257B2 (en) | 2011-03-29 |
| MY136518A (en) | 2008-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
| PPPP | Transfer of rights |
Owner name: BAYER ANIMAL HEALTH GMBH, DE |
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| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20090803 Year of fee payment: 9 |
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| ODBI | Application refused |