HRP20030046B1 - Pharmaceutical compositions for the treatment of mucositis, stomatitis and behcet's syndrome - Google Patents
Pharmaceutical compositions for the treatment of mucositis, stomatitis and behcet's syndromeInfo
- Publication number
- HRP20030046B1 HRP20030046B1 HR20030046A HRP20030046A HRP20030046B1 HR P20030046 B1 HRP20030046 B1 HR P20030046B1 HR 20030046 A HR20030046 A HR 20030046A HR P20030046 A HRP20030046 A HR P20030046A HR P20030046 B1 HRP20030046 B1 HR P20030046B1
- Authority
- HR
- Croatia
- Prior art keywords
- pharmaceutical compositions
- mucositis
- behcet
- stomatitis
- syndrome
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000027496 Behcet disease Diseases 0.000 title 1
- 208000009137 Behcet syndrome Diseases 0.000 title 1
- 206010028116 Mucosal inflammation Diseases 0.000 title 1
- 201000010927 Mucositis Diseases 0.000 title 1
- 208000003265 stomatitis Diseases 0.000 title 1
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- MPDGHEJMBKOTSU-UHFFFAOYSA-N Glycyrrhetinsaeure Natural products C12C(=O)C=C3C4CC(C)(C(O)=O)CCC4(C)CCC3(C)C1(C)CCC1C2(C)CCC(O)C1(C)C MPDGHEJMBKOTSU-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 229960003720 enoxolone Drugs 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Physiology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI001732A IT1318649B1 (it) | 2000-07-28 | 2000-07-28 | Composizioni farmaceutiche per il trattamento di mucositi e stomatiti. |
| PCT/EP2001/008303 WO2002009637A2 (en) | 2000-07-28 | 2001-07-18 | Pharmaceutical compositions for the treatment of mucositis, stomatitis and behcet's syndrome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20030046A2 HRP20030046A2 (en) | 2004-04-30 |
| HRP20030046B1 true HRP20030046B1 (en) | 2011-08-31 |
Family
ID=11445589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20030046A HRP20030046B1 (en) | 2000-07-28 | 2003-01-24 | Pharmaceutical compositions for the treatment of mucositis, stomatitis and behcet's syndrome |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20020173485A1 (zh) |
| EP (1) | EP1313489B1 (zh) |
| JP (1) | JP2004505028A (zh) |
| KR (1) | KR100761051B1 (zh) |
| CN (1) | CN1198625C (zh) |
| AR (1) | AR030068A1 (zh) |
| AT (1) | ATE289512T1 (zh) |
| AU (2) | AU2002212113B2 (zh) |
| BR (1) | BRPI0112962B8 (zh) |
| CA (1) | CA2424346C (zh) |
| CZ (1) | CZ301461B6 (zh) |
| DE (1) | DE60109044T2 (zh) |
| ES (1) | ES2236324T3 (zh) |
| HK (1) | HK1059215A1 (zh) |
| HR (1) | HRP20030046B1 (zh) |
| IT (1) | IT1318649B1 (zh) |
| MX (1) | MXPA03000712A (zh) |
| MY (1) | MY130477A (zh) |
| NO (1) | NO329574B1 (zh) |
| NZ (1) | NZ523832A (zh) |
| PL (1) | PL204397B1 (zh) |
| PT (1) | PT1313489E (zh) |
| RU (1) | RU2272636C2 (zh) |
| UA (1) | UA79075C2 (zh) |
| WO (1) | WO2002009637A2 (zh) |
| ZA (1) | ZA200300712B (zh) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2314049T3 (es) | 2001-02-15 | 2009-03-16 | Access Pharmaceuticals, Inc. | Formulaciones liquidas para la prevencion y el tratamiento de enfermedades y trastornos de la mucosa. |
| US7544348B2 (en) | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| US6585997B2 (en) | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
| BR0309890A (pt) | 2002-05-09 | 2005-05-10 | Medigenes | Composição farmacêutica contendo plasma sanguìneo, ou soro sanguìneo utilizada no tratamento de lesões, bem como seu método e processo de aplicação |
| US20060234977A1 (en) * | 2003-01-23 | 2006-10-19 | Gina Wenham | Antiviral compostion comprising a sulphated glucose polymer and a bacteriostatic agent |
| GB0312485D0 (en) * | 2003-05-30 | 2003-07-09 | Dodson & Horrell | Horse food composition |
| ITMI20031291A1 (it) | 2003-06-25 | 2004-12-26 | Ricerfarma Srl | Uso di acido ialuronico per la preparazione di composizioni per il trattamento di afte del cavo orale. |
| AU2003265624B2 (en) * | 2003-08-21 | 2011-03-31 | Abeona Therapeutics Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| WO2008027904A2 (en) * | 2006-08-28 | 2008-03-06 | Rexaderm, Inc. | Dry wound dressing and drug delivery system |
| KR100758636B1 (ko) * | 2006-12-19 | 2007-09-13 | 고려대학교 산학협력단 | 생체 점막 점착성 고분자 접합체 및 이의 제조방법 |
| PL2214679T3 (pl) | 2007-11-13 | 2019-09-30 | Meritage Pharma, Inc. | Kompozycje kortykosteroidów |
| US20090123390A1 (en) | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Compositions for the treatment of gastrointestinal inflammation |
| US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
| GB0813589D0 (en) * | 2008-07-24 | 2008-09-03 | Sinclair Pharmaceuticals Ltd | Composition |
| PL2435021T3 (pl) * | 2009-05-25 | 2014-03-31 | Sofar Swiss Sa | Zastosowanie połączenia glikozoaminoglikanowego o stałych proporcjach i kompozycji do żucia zawierającej wspomniane połączenie o stałych proporcjach |
| EP2557947A1 (en) | 2010-04-14 | 2013-02-20 | Altria Client Services Inc. | Preformed smokeless tobacco product |
| JP2013542250A (ja) * | 2010-11-12 | 2013-11-21 | コルゲート・パーモリブ・カンパニー | オーラルケア製品ならびにその使用方法および製造方法 |
| ES2388281B1 (es) | 2010-12-27 | 2013-10-01 | Laboratorios Viñas S.A. | Composición farmacéutica que comprende ácido hialurónico y un compuesto de zinc y pastilla con palito y procedimiento para preparación correspondientes |
| ITMI20110954A1 (it) * | 2011-05-26 | 2012-11-27 | Professional Dietetics Srl | Combinazioni per il trattamento delle mucositi vaginali o rettali |
| US10799548B2 (en) * | 2013-03-15 | 2020-10-13 | Altria Client Services Llc | Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products |
| EP3079656B8 (en) | 2013-10-16 | 2020-02-26 | Quest Products, LLC | Treating mucosal lesions with hyaluronan delivered from an adhering troche |
| CN105342987A (zh) * | 2015-12-04 | 2016-02-24 | 亚飞（上海）生物医药科技有限公司 | 一种凝胶及其制备方法和应用 |
| ITUA20161822A1 (it) * | 2016-03-18 | 2017-09-18 | Indena Spa | Composizioni utili nella prevenzione e/o nel trattamento di patologie del cavo orale, delle prime vie aeree e dell’esofago |
| JP6281968B1 (ja) * | 2016-07-27 | 2018-02-21 | 株式会社リタファーマ | 口腔粘膜貼付材及びその製造方法 |
| IT201600079773A1 (it) * | 2016-07-29 | 2018-01-29 | Matteo Bevilacqua | Composizioni contenenti oligosaccaridi di acido ialuronico (HA4), condroitin solfato (CS2-4) ed eparan solfato (HS2-4), triterpeni pentaciclici e derivati per uso medico curativo e metodo per la preparazione di tali composizioni. |
| CN106176863A (zh) * | 2016-08-04 | 2016-12-07 | 陈广圣 | 一种医用抗菌剂 |
| CN107802641A (zh) * | 2016-09-09 | 2018-03-16 | 李明典 | 口腔软组织(牙龈、粘膜)抗发炎酸痛剂 |
| EP3459368A1 (en) * | 2017-09-20 | 2019-03-27 | Geophyt S.r.L. | Food integrator for antineoplastic therapies |
| CN109331023A (zh) * | 2018-11-12 | 2019-02-15 | 沈阳药科大学 | 甘草次酸的医药用途 |
| KR102475125B1 (ko) | 2019-08-07 | 2022-12-07 | 고려대학교 산학협력단 | 일산화질소 복합체를 포함하는 구강 점막염 치료용 조성물 및 구강 점막염 치료제 |
| US20220362166A1 (en) * | 2019-10-25 | 2022-11-17 | Mucocort Ab | Treatment of inflammatory condition in mucous membrane or skin |
| IT202100011879A1 (it) * | 2021-05-10 | 2022-11-10 | Aurora Biofarma S R L | Composizione orale per il trattamento delle esofagiti |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2092442A (en) * | 1981-02-06 | 1982-08-18 | Biorex Laboratories Ltd | Pharmaceutical composition for treating diseases of the oral cavity, containing glycyrrhetinic acid or a derivative thereof |
| EP0444492A1 (en) * | 1990-02-21 | 1991-09-04 | RICERFARMA Srl | Topically administered compositions based on high molecular weight hyaluronic acid for treating inflammations of the oral cavity, and for oral cavity hygiene and cosmetic treatment |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA82361B (en) * | 1981-02-06 | 1982-12-29 | Biorex Laboratories Ltd | Pharmaceutical composition for treating diseases of the oral cavity |
| JPS6117510A (ja) * | 1984-07-03 | 1986-01-25 | Toyobo Co Ltd | 口腔粘膜適用徐放性ニフエジピン製剤 |
| JPS6440423A (en) * | 1987-08-05 | 1989-02-10 | Kyukyu Yakuhin Kogyo Kk | Patch for mucosa in oral cavity |
| US4965253A (en) * | 1987-10-14 | 1990-10-23 | University Of Florida | Viscoelastic material for ophthalmic surgery |
| JPH09169652A (ja) * | 1995-12-18 | 1997-06-30 | Lion Corp | 水性液状組成物 |
| JPH10182390A (ja) * | 1996-12-25 | 1998-07-07 | Lion Corp | 口腔用組成物 |
| JP2000178185A (ja) * | 1998-12-18 | 2000-06-27 | Lion Corp | 口腔粘膜付着型徐放性錠剤 |
-
2000
- 2000-07-28 IT IT2000MI001732A patent/IT1318649B1/it active
-
2001
- 2001-07-18 UA UA2003010420A patent/UA79075C2/uk unknown
- 2001-07-18 NZ NZ523832A patent/NZ523832A/en not_active IP Right Cessation
- 2001-07-18 AU AU2002212113A patent/AU2002212113B2/en not_active Expired
- 2001-07-18 CA CA002424346A patent/CA2424346C/en not_active Expired - Lifetime
- 2001-07-18 RU RU2003101393/15A patent/RU2272636C2/ru active
- 2001-07-18 MX MXPA03000712A patent/MXPA03000712A/es active IP Right Grant
- 2001-07-18 KR KR1020037001222A patent/KR100761051B1/ko active IP Right Grant
- 2001-07-18 AT AT01980213T patent/ATE289512T1/de active
- 2001-07-18 PL PL362921A patent/PL204397B1/pl unknown
- 2001-07-18 EP EP01980213A patent/EP1313489B1/en not_active Expired - Lifetime
- 2001-07-18 PT PT01980213T patent/PT1313489E/pt unknown
- 2001-07-18 CN CNB018134386A patent/CN1198625C/zh not_active Expired - Lifetime
- 2001-07-18 JP JP2002515192A patent/JP2004505028A/ja active Pending
- 2001-07-18 WO PCT/EP2001/008303 patent/WO2002009637A2/en active IP Right Grant
- 2001-07-18 CZ CZ20030262A patent/CZ301461B6/cs not_active IP Right Cessation
- 2001-07-18 AU AU1211302A patent/AU1211302A/xx active Pending
- 2001-07-18 BR BRPI0112962A patent/BRPI0112962B8/pt not_active IP Right Cessation
- 2001-07-18 ES ES01980213T patent/ES2236324T3/es not_active Expired - Lifetime
- 2001-07-18 DE DE60109044T patent/DE60109044T2/de not_active Expired - Lifetime
- 2001-07-27 AR ARP010103606A patent/AR030068A1/es not_active Application Discontinuation
- 2001-10-13 MY MYPI20014770A patent/MY130477A/en unknown
-
2002
- 2002-02-21 US US10/080,624 patent/US20020173485A1/en not_active Abandoned
-
2003
- 2003-01-24 HR HR20030046A patent/HRP20030046B1/xx not_active IP Right Cessation
- 2003-01-27 NO NO20030411A patent/NO329574B1/no not_active IP Right Cessation
- 2003-01-27 ZA ZA200300712A patent/ZA200300712B/xx unknown
-
2004
- 2004-03-16 HK HK04101910A patent/HK1059215A1/xx not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2092442A (en) * | 1981-02-06 | 1982-08-18 | Biorex Laboratories Ltd | Pharmaceutical composition for treating diseases of the oral cavity, containing glycyrrhetinic acid or a derivative thereof |
| EP0444492A1 (en) * | 1990-02-21 | 1991-09-04 | RICERFARMA Srl | Topically administered compositions based on high molecular weight hyaluronic acid for treating inflammations of the oral cavity, and for oral cavity hygiene and cosmetic treatment |
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