CN106176863A - 一种医用抗菌剂 - Google Patents

一种医用抗菌剂 Download PDF

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CN106176863A
CN106176863A CN201610628182.6A CN201610628182A CN106176863A CN 106176863 A CN106176863 A CN 106176863A CN 201610628182 A CN201610628182 A CN 201610628182A CN 106176863 A CN106176863 A CN 106176863A
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antibacterial
calomelas
sorbitol
ammonium salt
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陈广圣
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
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    • A61K33/28—Mercury; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
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  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明涉及一种医用抗菌剂，包括苯甲酸钠、白芷、铵盐、山梨糖醇、甘油、二羟基肉桂酸、艾叶、轻粉，各组分的质量份数为：苯甲酸钠7‑18份、白芷5‑8份、铵盐1‑3份、山梨糖醇1‑1.5份、甘油2‑8份、二羟基肉桂酸3.1‑4份、艾叶2‑3份、轻粉2‑6份。此抗菌剂具有稳定性好、使用量低、抗菌菌谱广、高效抗菌性、抗菌效果持续时间长等优点，广泛适用于各种日常生活领域和医学领域。

Description

一种医用抗菌剂
技术领域
本发明涉及一种抗菌剂。特别地，本发明涉及一种抗微生物、抗菌、抗真菌、抗病毒的医用抗菌剂。
背景技术
目前，临床在治疗各种感染性创面时，所采用的常规治疗方法是抗菌、消炎、清创。在治疗过程中所用的外用药物多为抗菌消炎药。但这些药物存在一定的不足之处。如临床上常用的四环素软膏、庆大霉素纱条、呋喃西林纱条等抗生素药物，随着其广泛且大剂量的应用，使敏感菌对其产生相应抗药性，故疗效不佳，再加上抗生素类药物只具有抗菌作用，并不能促进局部组织的血液循环和抑制创面渗出液的渗出，所以，一旦细菌出现抗药性，创面的感染即可进一步恶化，从而造成迁延不愈的恶果。在治疗中细菌虽不易产生抗药性，但其抗菌消炎作用以及促进组织愈合的作用均较弱，故伤口的愈合期较长。天然产品虽然安全，但一般昂贵，对广谱生物体如革兰氏阴性和革兰氏阳性细菌及真菌没有杀生物效果。大多数天然产品在相对高浓度下仅对革兰氏阳性细菌有效，而对革兰氏阴性细菌或真菌无效。
发明内容
针对现有技术中存在的上述不足，本发明所要解决的技术问题是提供一种效果好的医用抗菌剂。
本发明解决其技术问题所采用的技术方案是：提供一种医用抗菌剂，包括苯甲酸钠、白芷、铵盐、山梨糖醇、甘油、二羟基肉桂酸、艾叶、轻粉，各组分的质量份数为：苯甲酸钠7-18份、白芷5-8份、铵盐1-3份、山梨糖醇1-1.5份、甘油2-8份、二羟基肉桂酸3.1-4份、艾叶2-3份、轻粉2-6份。
作为优选，所述的医用抗菌剂，各组分的质量份数为：苯甲酸钠7份、白芷5份、铵盐1份、山梨糖醇1份、甘油2份、二羟基肉桂酸3.1份、艾叶2份、轻粉2份。
作为优选，所述的抗菌剂组份按中草药制剂中常规的提取方法，提取其有效成份，制备成软膏，对创伤面或者感染处进行涂沫。
此抗菌剂具有稳定性好、使用量低、抗菌菌谱广、高效抗菌性、抗菌效果持续时间长等优点，广泛适用于各种日常生活领域和医学领域；
各个组分的有机组合使其增加了改善和调解机体免疫抑制状态的作用，加快了伤口的愈合，可使炎症处的小血管收缩，减轻局部充血、抑制透明脂酸酶的活性，从而降低毛细血管的通透性，使炎症浸润和渗出减少，可缓解炎症所引起的反应，同时还能抑制纤维细胞增生和肉芽组织的形成，可减轻炎症引起的粘连成形的疤痕，具有显著的抗菌作用。
具体实施方式
本发明提供的一种医用抗菌剂，包括苯甲酸钠、白芷、铵盐、山梨糖醇、甘油、二羟基肉桂酸、艾叶、轻粉，各组分的质量份数为：苯甲酸钠7-18份、白芷5-8份、铵盐1-3份、山梨糖醇1-1.5份、甘油2-8份、二羟基肉桂酸3.1-4份、艾叶2-3份、轻粉2-6份。
作为优选，所述的医用抗菌剂，各组分的质量份数为：苯甲酸钠7份、白芷5份、铵盐1份、山梨糖醇1份、甘油2份、二羟基肉桂酸3.1份、艾叶2份、轻粉2份。
作为优选，所述的抗菌剂组份按中草药制剂中常规的提取方法，提取其有效成份，制备成软膏，对创伤面或者感染处进行涂沫。
以上所述，仅是对本发明的较佳实施例而已，并非对本发明做其他形式的限制，任何熟悉本专业的技术人员可能利用上述揭示的技术内容加以变更或改型为同等变化的等效实施例。凡是未脱离本发明方案内容，依据本发明的技术实质对以上实施例所做的任何简单修改、等同变化与改型，均落在本发明的保护范围内。

Claims (3)

1.一种医用抗菌剂，包括苯甲酸钠、白芷、铵盐、山梨糖醇、甘油、二羟基肉桂酸、艾叶、轻粉，各组分的质量份数为：苯甲酸钠7-18份、白芷5-8份、铵盐1-3份、山梨糖醇1-1.5份、甘油2-8份、二羟基肉桂酸3.1-4份、艾叶2-3份、轻粉2-6份。
2.根据权利要求1所述的医用抗菌剂，各组分的质量份数为：苯甲酸钠7份、白芷5份、铵盐1份、山梨糖醇1份、甘油2份、二羟基肉桂酸3.1份、艾叶2份、轻粉2份。
3.将权利要求1-2所述的抗菌剂组份按中草药制剂中常规的提取方法，提取其有效成份，制备成软膏，对创伤面或者感染处进行涂沫。
CN201610628182.6A 2016-08-04 2016-08-04 一种医用抗菌剂 Pending CN106176863A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111676731A (zh) * 2020-05-12 2020-09-18 仙鹤股份有限公司 一种医用皱纹纸的制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1474700A (zh) * 2000-07-28 2004-02-11 ������ҩ�����޹�˾ 用于治疗粘膜炎、口炎和贝赫切特综合征的药物组合物
CN103040922A (zh) * 2012-12-17 2013-04-17 青岛研博电子有限公司 抗菌组合物
CN103495199A (zh) * 2013-10-08 2014-01-08 山东赛克赛斯药业科技有限公司 一种治疗激光灼伤和烧烫伤的水凝胶伤口敷料及其制备方法
CN104448557A (zh) * 2014-11-24 2015-03-25 苏州市贝克生物科技有限公司 一种医用有机硅季铵盐抗菌剂改性pp及其制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1474700A (zh) * 2000-07-28 2004-02-11 ������ҩ�����޹�˾ 用于治疗粘膜炎、口炎和贝赫切特综合征的药物组合物
CN103040922A (zh) * 2012-12-17 2013-04-17 青岛研博电子有限公司 抗菌组合物
CN103495199A (zh) * 2013-10-08 2014-01-08 山东赛克赛斯药业科技有限公司 一种治疗激光灼伤和烧烫伤的水凝胶伤口敷料及其制备方法
CN104448557A (zh) * 2014-11-24 2015-03-25 苏州市贝克生物科技有限公司 一种医用有机硅季铵盐抗菌剂改性pp及其制备方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111676731A (zh) * 2020-05-12 2020-09-18 仙鹤股份有限公司 一种医用皱纹纸的制备方法
CN111676731B (zh) * 2020-05-12 2022-01-18 仙鹤股份有限公司 一种医用皱纹纸的制备方法

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