HRP20000363B1 - Imidazonaphthyridines and their use in inducing cytokine biosynthesis - Google Patents

Imidazonaphthyridines and their use in inducing cytokine biosynthesis

Info

Publication number
HRP20000363B1
HRP20000363B1 HR20000363A HRP20000363A HRP20000363B1 HR P20000363 B1 HRP20000363 B1 HR P20000363B1 HR 20000363 A HR20000363 A HR 20000363A HR P20000363 A HRP20000363 A HR P20000363A HR P20000363 B1 HRP20000363 B1 HR P20000363B1
Authority
HR
Croatia
Prior art keywords
compounds
imidazonaphthyridines
cytokine biosynthesis
inducing cytokine
biosynthesis
Prior art date
Application number
HR20000363A
Other languages
English (en)
Inventor
J. Lindstrom Kyle
F. Gerster John
L. Crooks Stephen
D. Heppner Philip
J. Marszalek Gregory
V. Maye Peter
A. Merrill Bryon
W. Mickelson John
J. Rice Michael
Original Assignee
Minnesota Mining & Manufacturing Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining & Manufacturing Company filed Critical Minnesota Mining & Manufacturing Company
Publication of HRP20000363A2 publication Critical patent/HRP20000363A2/hr
Publication of HRP20000363B1 publication Critical patent/HRP20000363B1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61P11/02—Nasal agents, e.g. decongestants
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
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    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
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    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

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  • Organic Chemistry (AREA)
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  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20000363A 1997-12-11 1998-12-11 Imidazonaphthyridines and their use in inducing cytokine biosynthesis HRP20000363B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6927697P 1997-12-11 1997-12-11
PCT/US1998/026473 WO1999029693A1 (en) 1997-12-11 1998-12-11 Imidazonaphthyridines and their use in inducing cytokine biosynthesis

Publications (2)

Publication Number Publication Date
HRP20000363A2 HRP20000363A2 (en) 2001-06-30
HRP20000363B1 true HRP20000363B1 (en) 2005-06-30

Family

ID=22087889

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000363A HRP20000363B1 (en) 1997-12-11 1998-12-11 Imidazonaphthyridines and their use in inducing cytokine biosynthesis

Country Status (27)

Country Link
US (14) US6194425B1 (enExample)
EP (1) EP1040112B1 (enExample)
JP (4) JP4283438B2 (enExample)
KR (3) KR100642703B1 (enExample)
CN (1) CN1154647C (enExample)
AT (3) ATE338757T1 (enExample)
AU (1) AU753864B2 (enExample)
BR (1) BR9814275A (enExample)
CA (1) CA2311456C (enExample)
CZ (1) CZ307184B6 (enExample)
DE (3) DE69835309T2 (enExample)
DK (1) DK1512686T3 (enExample)
EE (1) EE04314B1 (enExample)
ES (3) ES2270249T3 (enExample)
HR (1) HRP20000363B1 (enExample)
HU (1) HUP0101155A3 (enExample)
IL (4) IL136556A0 (enExample)
NO (3) NO316687B1 (enExample)
NZ (1) NZ504776A (enExample)
PL (1) PL193915B1 (enExample)
PT (3) PT1512686E (enExample)
RU (3) RU2312867C2 (enExample)
SI (1) SI1512686T1 (enExample)
SK (2) SK286304B6 (enExample)
TR (1) TR200001705T2 (enExample)
UA (1) UA67760C2 (enExample)
WO (1) WO1999029693A1 (enExample)

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KR20010101420A (ko) 1999-01-08 2001-11-14 캐롤린 에이. 베이츠 면역반응 조절제로 점막 관련 질환을 치료하기 위한조성물 및 방법
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AU2002232498B2 (en) * 2000-12-08 2006-05-04 3M Innovative Properties Company Screening method for identifying compounds that selectively induce interferon alpha
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US6664260B2 (en) * 2000-12-08 2003-12-16 3M Innovative Properties Company Heterocyclic ether substituted imidazoquinolines
US6664264B2 (en) * 2000-12-08 2003-12-16 3M Innovative Properties Company Thioether substituted imidazoquinolines
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