HK83293A - Composition of pregnanolole comprising a stable oil-in-water emulsion - Google Patents
Composition of pregnanolole comprising a stable oil-in-water emulsion Download PDFInfo
- Publication number
- HK83293A HK83293A HK832/93A HK83293A HK83293A HK 83293 A HK83293 A HK 83293A HK 832/93 A HK832/93 A HK 832/93A HK 83293 A HK83293 A HK 83293A HK 83293 A HK83293 A HK 83293A
- Authority
- HK
- Hong Kong
- Prior art keywords
- amount
- oil
- pregnanolone
- composition
- emulsion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8600632A SE8600632D0 (sv) | 1986-02-13 | 1986-02-13 | Novel pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK83293A true HK83293A (en) | 1993-08-20 |
Family
ID=20363448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK832/93A HK83293A (en) | 1986-02-13 | 1993-08-12 | Composition of pregnanolole comprising a stable oil-in-water emulsion |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5028600A (cs) |
| EP (1) | EP0233849B1 (cs) |
| JP (1) | JPH0788305B2 (cs) |
| AT (1) | ATE64526T1 (cs) |
| CA (1) | CA1301651C (cs) |
| DE (1) | DE3770830D1 (cs) |
| DK (1) | DK175504B1 (cs) |
| ES (1) | ES2037742T3 (cs) |
| FI (1) | FI88676C (cs) |
| GR (1) | GR3002299T3 (cs) |
| HK (1) | HK83293A (cs) |
| NO (1) | NO175040B (cs) |
| SE (1) | SE8600632D0 (cs) |
| SG (1) | SG102892G (cs) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9302295D0 (sv) * | 1993-07-02 | 1993-07-02 | Kabi Pharmacia Ab | New pharmaceutical composition |
| US5616330A (en) * | 1994-07-19 | 1997-04-01 | Hemagen/Pfc | Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same |
| AU8779898A (en) * | 1997-08-11 | 1999-03-01 | Weider Nutrition International, Inc. | Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors |
| HK1040195B (zh) | 1998-08-19 | 2006-06-02 | Skyepharma Canada Inc. | 普鲁泊福的可注射水分散体 |
| WO2002053102A2 (en) * | 2000-12-29 | 2002-07-11 | The Trustees Of Columbia University In The City Of New York | Use of iv emulsions with different triglyceride composition, particle size and apolipoprotein e for targeted tissue delivery of hydrophobic compounds |
| PL224989B1 (pl) * | 2002-07-02 | 2017-02-28 | Nycomed Gmbh | Sposób wytwarzania sterylnej wodnej zawiesiny zawierającej cyklezonid |
| PE20050941A1 (es) | 2003-12-16 | 2005-11-08 | Nycomed Gmbh | Suspensiones acuosas de ciclesonida para nebulizacion |
| MX2007002941A (es) * | 2004-09-13 | 2007-05-24 | Bharat Serums & Vaccines Ltd | Composiciones de emulsion estables para administracion intravenosa que tienen eficacia libre de conservadores. |
| CN104739765A (zh) * | 2011-01-14 | 2015-07-01 | 卡思伯特·O·辛普金斯 | 用于处理与缺乏血液供给、休克和神经损伤相关的疾病的方法和组合物 |
| US10478505B2 (en) | 2011-09-23 | 2019-11-19 | The Regents Of The University Of California | Edible oils to enhance delivery of orally administered steroids |
| MX2014008895A (es) | 2012-01-23 | 2014-11-25 | Sage Therapeutics Inc | Formulaciones de esteroides neuroactivos y metodos para tratar trastornos del cns. |
| WO2014028398A2 (en) | 2012-08-13 | 2014-02-20 | The Regents Of The University Of California | Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids |
| IL294306B2 (en) | 2012-08-21 | 2024-01-01 | Sage Therapeutics Inc | Treatment methods for epilepsy and status epilepticus |
| WO2014085668A1 (en) | 2012-11-30 | 2014-06-05 | The Regents Of The University Of California | Anticonvulsant activity of steroids |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| RU2766155C2 (ru) | 2016-03-08 | 2022-02-08 | Сейдж Терапьютикс, Инк. | Нейроактивные стероиды, их композиции и применения |
| CA3123002A1 (en) * | 2018-12-10 | 2020-06-18 | Halo Science LLC | Stable formulations of anesthetics and associated dosage forms |
| CA3151334C (en) * | 2019-08-19 | 2024-04-09 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Topical neurosteroid formulations |
| US11969434B1 (en) | 2022-08-29 | 2024-04-30 | Lipocine Inc. | Oral allopregnanolone compositions and methods of use |
| CN114344309B (zh) * | 2021-12-30 | 2024-02-06 | 南京迈诺威医药科技有限公司 | 一种别孕烷醇酮衍生物自乳化制剂及其制备方法 |
| US12186327B2 (en) | 2022-08-29 | 2025-01-07 | Lipocine Inc. | Oral allopregnanolone compositions and methods of use |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1215702B (de) * | 1962-07-03 | 1966-05-05 | Merck Ag E | Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen |
| CA895860A (en) * | 1969-11-05 | 1972-03-21 | Kruger Gunther | PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE |
| US3917830A (en) * | 1970-12-17 | 1975-11-04 | Glaxo Lab Ltd | Steroidal anaesthetic composition for intraveneous injection |
| US3900561A (en) * | 1970-12-17 | 1975-08-19 | Glaxo Lab Ltd | Pharmaceutical compositions |
| US4168308A (en) * | 1976-03-12 | 1979-09-18 | Apoteksvarucentralen Vitrum Ab | Composition for enhancing the administration of pharmacologically active agents |
| JPS609726B2 (ja) * | 1980-05-15 | 1985-03-12 | 株式会社 ミドリ十字 | ステロイド製剤 |
| JPS5716818A (en) * | 1981-04-25 | 1982-01-28 | Green Cross Corp:The | Steroid fatty emulsion |
| JPS60258110A (ja) * | 1984-06-05 | 1985-12-20 | Daigo Eiyou Kagaku Kk | 静脈注射可能なプロゲステロン乳化注射液 |
-
1986
- 1986-02-13 SE SE8600632A patent/SE8600632D0/xx unknown
-
1987
- 1987-01-29 DE DE8787850029T patent/DE3770830D1/de not_active Expired - Fee Related
- 1987-01-29 EP EP87850029A patent/EP0233849B1/en not_active Expired - Lifetime
- 1987-01-29 ES ES198787850029T patent/ES2037742T3/es not_active Expired - Lifetime
- 1987-01-29 AT AT87850029T patent/ATE64526T1/de not_active IP Right Cessation
- 1987-02-06 DK DK198700621A patent/DK175504B1/da not_active IP Right Cessation
- 1987-02-12 FI FI870589A patent/FI88676C/fi not_active IP Right Cessation
- 1987-02-12 JP JP62028395A patent/JPH0788305B2/ja not_active Expired - Fee Related
- 1987-02-12 CA CA000529609A patent/CA1301651C/en not_active Expired - Fee Related
- 1987-02-12 NO NO870560A patent/NO175040B/no not_active IP Right Cessation
-
1989
- 1989-02-28 US US07/316,576 patent/US5028600A/en not_active Expired - Lifetime
-
1991
- 1991-07-11 GR GR91400996T patent/GR3002299T3/el unknown
-
1992
- 1992-10-07 SG SG1028/92A patent/SG102892G/en unknown
-
1993
- 1993-08-12 HK HK832/93A patent/HK83293A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI88676B (fi) | 1993-03-15 |
| FI870589A0 (fi) | 1987-02-12 |
| GR3002299T3 (en) | 1992-12-30 |
| ES2037742T3 (es) | 1993-07-01 |
| NO870560D0 (no) | 1987-02-12 |
| EP0233849A1 (en) | 1987-08-26 |
| SG102892G (en) | 1992-12-04 |
| FI88676C (fi) | 1993-06-28 |
| DK62187D0 (da) | 1987-02-06 |
| ATE64526T1 (de) | 1991-07-15 |
| DK62187A (da) | 1987-08-14 |
| SE8600632D0 (sv) | 1986-02-13 |
| EP0233849B1 (en) | 1991-06-19 |
| DE3770830D1 (de) | 1991-07-25 |
| DK175504B1 (da) | 2004-11-15 |
| NO175040C (cs) | 1994-08-24 |
| NO175040B (no) | 1994-05-16 |
| NO870560L (no) | 1987-08-14 |
| JPH0788305B2 (ja) | 1995-09-27 |
| CA1301651C (en) | 1992-05-26 |
| JPS62192322A (ja) | 1987-08-22 |
| FI870589L (fi) | 1987-08-14 |
| US5028600A (en) | 1991-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20060129 |